Page last updated: 2024-08-17

levodopa and mavoglurant

levodopa has been researched along with mavoglurant in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Destee, A; Gao, H; Graf, A; Hattori, N; Hauser, RA; Kenney, C; Lang, AE; Merschhemke, M; Nagel, J; Poewe, W; Rascol, O; Stacy, M; Stocchi, F; Tolosa, E; Trenkwalder, C1
Dronamraju, N; Graf, A; Hauser, RA; Kenney, C; Kumar, R; Merschhemke, M; Mostillo, J1
Auladell, C; Beas-Zarate, C; Camins, A; Canudas, AM; de Lemos, ML; Folch, J; Lazarowski, A; Pallàs, M; Pedros, I; Petrov, D1
Bilbe, G; Bouhelal, R; Desrayaud, S; Enz, A; Flor, PJ; Gasparini, F; Kuhn, R; McAllister, K; Ofner, S; Vranesic, I1
Dronamraju, N; Graf, A; Kenney, C; Poewe, W; Shah, A; Stocchi, F; Trenkwalder, C; von Raison, F1
Ahmed, H; Aziz, MAE; Bahbah, EI; Ebada, MA; Fala, SY; Ghaith, HS; Negida, A1

Reviews

2 review(s) available for levodopa and mavoglurant

ArticleYear
Mavoglurant as a treatment for Parkinson's disease.
    Expert opinion on investigational drugs, 2014, Volume: 23, Issue:8

    Topics: Allosteric Regulation; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Indoles; Levodopa; Parkinson Disease; Quality of Life; Receptor, Metabotropic Glutamate 5

2014
Mavoglurant (AFQ056) for the treatment of levodopa-induced dyskinesia in patients with Parkinson's disease: a meta-analysis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:8

    Topics: Activities of Daily Living; Antiparkinson Agents; Dyskinesias; Humans; Indoles; Levodopa; Parkinson Disease

2021

Trials

3 trial(s) available for levodopa and mavoglurant

ArticleYear
AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study.
    Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:13

    Topics: Aged; Antiparkinson Agents; Cognition Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Humans; Indoles; International Cooperation; Levodopa; Male; Middle Aged; Outcome Assessment, Health Care; Parkinson Disease; Psychiatric Status Rating Scales; Severity of Illness Index; Time Factors

2013
Mavoglurant (AFQ056) in combination with increased levodopa dosages in Parkinson's disease patients.
    The International journal of neuroscience, 2016, Volume: 126, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Early Termination of Clinical Trials; Excitatory Amino Acid Antagonists; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Kainic Acid; Sample Size; Severity of Illness Index; Tremor

2016
Mavoglurant in Parkinson's patients with l-Dopa-induced dyskinesias: Two randomized phase 2 studies.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:7

    Topics: Aged; Antiparkinson Agents; Dopamine Agents; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Outcome Assessment, Health Care; Parkinson Disease

2016

Other Studies

1 other study(ies) available for levodopa and mavoglurant

ArticleYear
AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization.
    Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

    Topics: Animals; Brain; Dyskinesia, Drug-Induced; Half-Life; High-Throughput Screening Assays; Humans; Hyperthermia, Induced; Indoles; Levodopa; Male; Mice; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship

2014