Page last updated: 2024-08-17

levodopa and leucine

levodopa has been researched along with leucine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's2 (9.09)18.2507
2000's5 (22.73)29.6817
2010's4 (18.18)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S1
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H1
Avdeef, A; Tam, KY1
Boegman, RJ; Wood, PL1
Wick, MM1
Drewes, LR; Gilboe, DD1
Kobayashi, S1
Garcia-Sancho, FJ; Herreros, B1
Burke, WJ; Joh, TH1
Lindström, P; Sehlin, J1
Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ1
Cooper, RL; Linnoila, M1
Fahn, S; Floud, A1
Ahrenstedt, O; Aquilonius, SM; Knutson, L; Lennernäs, H; Nilsson, D; Paalzow, LK1
Dória, S; Gomes, P; Jose, PA; Serrão, P; Soares-da-Silva, P; Xu, J1
Fraga, S; Serrão, MP; Soares-da-Silva, P1
Serrão, MP; Soares-da-Silva, P1
Calas, A; Kurina, A; Pronina, T; Sapronova, A; Sorokin, A; Taxi, J; Ugrumov, M1
de Boer, AH; Frijlink, HW; Grasmeijer, F; Hagedoorn, P; Luinstra, M; Moes, JR1
Kudrin, VS; Kurina, AU; Pronina, TS; Ugrumov, MV1
Bahrainian, S; Gilani, K; Gilani, Z; Mirmoeini, MS1

Other Studies

22 other study(ies) available for levodopa and leucine

ArticleYear
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship

1998
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
    Genomics, 2002, Volume: 79, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis

2002
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Monoamines as possible mediators in the regulation of fast axoplasmic flow.
    Journal of neurochemistry, 1976, Volume: 26, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Axonal Transport; Biogenic Amines; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Combinations; Leucine; Levodopa; Male; Pargyline; Rats; Reserpine; Serotonin; Spinal Cord

1976
L-Dopa methyl ester: prolongation of survival of neuroblastoma-bearing mice after treatment.
    Science (New York, N.Y.), 1978, Feb-17, Volume: 199, Issue:4330

    Topics: Animals; Benserazide; Cell Line; Drug Synergism; Leucine; Levodopa; Male; Mice; Neoplasms, Experimental; Neuroblastoma; Thymidine; Uridine

1978
Nutrient transport systems in dog brain.
    Federation proceedings, 1977, Volume: 36, Issue:2

    Topics: Adenine; Amino Acids; Animals; Biological Transport; Blood-Brain Barrier; Dogs; Erythrocytes; Glutamates; In Vitro Techniques; Ions; Leucine; Levodopa; Oxygenators, Membrane; Palmitic Acids; Perfusion; Thymine; Urea

1977
Uptake and intracellular localization of exogenous L-DOPA, L-leucine and their metabolites in the gastro-enteric endocrine cells of the mouse studied by electron microscope autoradiography.
    Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 1975, Volume: 37, Issue:4

    Topics: Animals; Autoradiography; Cytoplasmic Granules; Duodenum; Gastric Mucosa; Gastrointestinal Hormones; Histocytochemistry; Leucine; Levodopa; Male; Mice; Microscopy, Electron; Stomach; Tritium

1975
Characterization of transport systems for the transfer of 3,4-L-dihydroxyphenylalanine into slices of rat cerebral cortex.
    Biochimica et biophysica acta, 1975, Nov-03, Volume: 406, Issue:4

    Topics: Alanine; Amino Acids; Animals; Biological Transport; Cerebral Cortex; Histidine; Kinetics; Leucine; Levodopa; Male; Potassium; Rats; Sodium

1975
Effect of dopamine on tyrosine hydroxylase in cultured rat adrenal medulla.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Adrenal Medulla; Animals; Culture Techniques; Dopamine; Leucine; Levodopa; Male; Protein Biosynthesis; Rats; Tyrosine 3-Monooxygenase

1988
Effects of substrates for aromatic L-amino acid decarboxylase on insulin secretion.
    Acta endocrinologica, 1987, Volume: 116, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Levodopa; Mice; Mice, Obese; Tyrosine

1987
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors

1974
Effects of centrally and systemically administered L-tyrosine and L-leucine on ovarian function in the old rat.
    Gerontology, 1980, Volume: 26, Issue:5

    Topics: Aging; Animals; Catecholamines; Estrus; Female; Leucine; Levodopa; Ovary; Pregnancy; Preoptic Area; Rats; Serotonin; Tyrosine

1980
L-DOPA (L-3,4-dihydroxyphenylalanine) uptake by human red blood cells.
    Biochimica et biophysica acta, 1981, Jul-20, Volume: 645, Issue:2

    Topics: Biological Transport; Cell Membrane Permeability; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leucine; Levodopa; Tryptophan

1981
The effect of L-leucine on the absorption of levodopa, studied by regional jejunal perfusion in man.
    British journal of clinical pharmacology, 1993, Volume: 35, Issue:3

    Topics: Adult; Antipyrine; Benserazide; Female; Glucose; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestine, Small; Jejunum; Leucine; Levodopa; Male; Perfusion; Stereoisomerism

1993
Expression and function of sodium transporters in two opossum kidney cell clonal sublines.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:1

    Topics: Amiloride; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biological Transport; Catechol O-Methyltransferase; Clone Cells; Diuretics; Epithelial Cells; Hypertension, Renal; Immunoblotting; Kidney; Leucine; Levodopa; LLC-PK1 Cells; Methylglucosides; Microscopy, Electron, Scanning; Opossums; p-Aminohippuric Acid; Parathyroid Hormone; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Swine

2002
The L-3,4-dihydroxyphenylalanine transporter in human and rat epithelial intestinal cells is a type 2 hetero amino acid exchanger.
    European journal of pharmacology, 2002, Apr-26, Volume: 441, Issue:3

    Topics: Amino Acid Transport Systems; Animals; Caco-2 Cells; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Intestinal Mucosa; Intestines; Leucine; Levodopa; Rats

2002
High- and low-affinity transport of L-leucine and L-DOPA by the hetero amino acid exchangers LAT1 and LAT2 in LLC-PK1 renal cells.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:2

    Topics: Animals; Biological Transport; Hydrogen-Ion Concentration; Kidney; Large Neutral Amino Acid-Transporter 1; Leucine; Levodopa; LLC-PK1 Cells; Sodium; Swine; Transcription, Genetic

2004
Neurons expressing individual enzymes of dopamine synthesis in the mediobasal hypothalamus of adult rats: functional significance and topographic interrelations.
    Neuroscience, 2014, Sep-26, Volume: 277

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatic-L-Amino-Acid Decarboxylases; Central Nervous System Agents; Chromatography, High Pressure Liquid; Dopamine; Immunohistochemistry; Leucine; Levodopa; Male; Microscopy, Electron; Neurons; Rats, Wistar; Substantia Nigra; Tissue Culture Techniques; Tyrosine 3-Monooxygenase

2014
A levodopa dry powder inhaler for the treatment of Parkinson's disease patients in off periods.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 97, Issue:Pt A

    Topics: Administration, Inhalation; Aerosols; Antiparkinson Agents; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Dry Powder Inhalers; Excipients; Humans; Leucine; Levodopa; Parkinson Disease; Reproducibility of Results; Tissue Distribution

2015
Missing proof of cooperative synthesis of dopamine by non-dopaminergic neurons.
    Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1

    Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzophenones; Catechol O-Methyltransferase Inhibitors; Coculture Techniques; Dopamine; Hypothalamus; Isotonic Solutions; Leucine; Levodopa; Male; Neurons; Nitrophenols; Rats, Wistar; Substantia Nigra; Tolcapone; Tyrosine 3-Monooxygenase

2016
Engineering of levodopa inhalable microparticles in combination with leucine and dipalmitoylphosphatidylcholine by spray drying technique.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2021, Dec-01, Volume: 167

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Inhalation; Aerosols; Dry Powder Inhalers; Leucine; Levodopa; Particle Size; Powders; Spray Drying

2021