Page last updated: 2024-08-17

levodopa and indomethacin

levodopa has been researched along with indomethacin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's2 (9.09)18.2507
2000's7 (31.82)29.6817
2010's10 (45.45)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Avgoustakis, K; Bariamis, SE; Drainas, D; Hadjipavlou-Litina, D; Magoulas, GE; Papaioannou, D1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dinari, G; Kiro, A; Marcus, H; Zahavi, I1
Hashimoto, H; Hasui, M; Igarashi, N; Kato, E; Minami, S; Okabe, T; Sato, T1
Catron, PW; Flynn, ET1
Castaneda, AA; Cross, JM; Gunter, JA; Mercer, DW1
Drukarch, B; Jongenelen, CA; LaFleur, MV; Peters, GJ; Riemers, FM; Siegel, D; van Muiswinkel, FL1
Kohút, A; Sarisský, M; Sedlakova, A1
Asanuma, M; Kikkawa, Y; Kimoto, N; Miyazaki, I; Miyoshi, K; Murakami, S; Takeshima, M1
Egan, T; Kuriakose, A; Rentsch, P; Stayte, S; Vissel, B1

Reviews

1 review(s) available for levodopa and indomethacin

ArticleYear
Adjuvant drug therapy for decompression sickness: a review.
    Undersea biomedical research, 1982, Volume: 9, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Anti-Arrhythmia Agents; Aspirin; Bronchodilator Agents; Coumarins; Cyproheptadine; Decompression Sickness; Dextrans; Diazepam; Dipyridamole; Fluid Therapy; Heparin; Humans; Indomethacin; Levodopa; Niacin; Vasoconstrictor Agents; Vasodilator Agents

1982

Other Studies

21 other study(ies) available for levodopa and indomethacin

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?
    Bioorganic & medicinal chemistry, 2010, Dec-01, Volume: 18, Issue:23

    Topics: Acitretin; Animals; Anti-Inflammatory Agents; Antioxidants; Edema; Levodopa; Lipid Peroxidation; Rats; Spermine; Tretinoin

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
L-dopa is protective against indomethacin-induced small intestinal ulceration in the rat: possible role of an alpha-2-adrenergic mechanism.
    Life sciences, 1992, Volume: 51, Issue:14

    Topics: Animals; Clonidine; Haloperidol; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Ulcer; Yohimbine

1992
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
    Acta endocrinologica, 1988, Volume: 117, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinoprostone; Dopamine; Epinephrine; Female; Humans; Hypertension; Indomethacin; Levodopa; Metoclopramide; Norepinephrine; Periodicity; Prostaglandins E; Psychotic Disorders; Recurrence; Syndrome; Vomiting

1988
Gastroprotective actions of bombesin, L-DOPA, and mild irritants: roles of prostaglandins and sensory neurons.
    Surgery, 1998, Volume: 124, Issue:5

    Topics: Adaptation, Physiological; Animals; Bombesin; Capsaicin; Cyclooxygenase Inhibitors; Dopamine Agents; Ethanol; Female; Indomethacin; Irritants; Levodopa; Neurons, Afferent; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Stomach

1998
L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H:quinone oxidoreductase (NQO) in cultured astroglial cells.
    Free radical biology & medicine, 2000, Sep-01, Volume: 29, Issue:5

    Topics: Animals; Animals, Newborn; Astrocytes; Astrocytoma; Cells, Cultured; Dicumarol; Gene Expression Regulation, Enzymologic; Indomethacin; Levodopa; NAD(P)H Dehydrogenase (Quinone); Polymerase Chain Reaction; Rats; Tumor Cells, Cultured

2000
Changes of gastric lipase activity after ethanol and indomethacin administration: influence of pretreatment with allopurinol, pentoxifylline and L-DOPA.
    Physiological research, 2001, Volume: 50, Issue:3

    Topics: Allopurinol; Animals; Central Nervous System Depressants; Cyclooxygenase Inhibitors; Dopamine Agents; Enzyme Inhibitors; Ethanol; Fatty Acids, Nonesterified; Gastric Mucosa; Indomethacin; Levodopa; Lipase; Male; Pentoxifylline; Rats; Rats, Wistar; Triglycerides; Xanthine Oxidase

2001
Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity.
    Neurochemical research, 2012, Volume: 37, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dopamine Agents; Dopaminergic Neurons; Glutathione; Indomethacin; Levodopa; Meloxicam; Methyldopa; Mice; Neurons; Neuroprotective Agents; Quinones; Sympatholytics; Thiazines; Thiazoles

2012
The ratio of M1 to M2 microglia in the striatum determines the severity of L-Dopa-induced dyskinesias.
    Journal of neurochemistry, 2023, Volume: 167, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antiparkinson Agents; Corpus Striatum; Dyskinesias; Indomethacin; Inflammation; Levodopa; Mice; Microglia; Minocycline; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley

2023