levodopa has been researched along with homovanillic acid in 339 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 152 (44.84) | 18.7374 |
| 1990's | 106 (31.27) | 18.2507 |
| 2000's | 58 (17.11) | 29.6817 |
| 2010's | 20 (5.90) | 24.3611 |
| 2020's | 3 (0.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Davidson, L; Hornykiewicz, O; Lloyd, KG | 1 |
| Butler, IJ; Koslow, SH | 1 |
| Butler, IJ; Holtzman, NA; Kaufman, S; Koslow, SH; Krumholz, A | 1 |
| Grönfors, N; Hietala, P; Lindén, IB | 1 |
| Gordon, JI; Mann, SP | 1 |
| Costentin, J | 1 |
| de Vries, JA; Fremouw-Ottevangers, DC; Muskiet, FA; van der Meulen, J; Wolthers, BG | 1 |
| Moskowitz, MA; Wurtman, RJ | 1 |
| Klawans, H | 1 |
| Sishta, SK; Templer, DI | 1 |
| Bertolino, A; Di Reda, L; Giovine, A; Livrea, P | 1 |
| Abbruzzese, G; Albano, C; La Medica, G; Loeb, C; Roccatagliata, G | 1 |
| Chase, TN | 3 |
| Goetz, C; Klawans, HL; Nausieda, PA; Weiner, WJ | 1 |
| Bernheim-Chatelain, C; Ecoffet, M; Gilbert, JC; Jaillon, P; Willer, JC | 1 |
| Fukuyama, Y; Hayakawa, T; Miyagawa, F; Ochiai, Y | 1 |
| Korf, J; Lakke, JP; van Praagen, HM | 1 |
| Filion, M; Langelier, P; Larochelle, L; Poirier, L | 1 |
| Davidson, L; Gall, DG; Lloyd, KG; McClung, HJ; Price, K | 1 |
| Kobayashi, K; Mori, A | 1 |
| Maître, L; Waldmeier, PC | 2 |
| Comi, R; Fahn, S; Prasad, AL; Snider, SR | 1 |
| Green, JP; Mizoguchi, H; Orlowski, M; Wilk, S | 1 |
| Cremer, H; Neuhoff, V; Osborne, NN; Sontag, KH; Wand, P | 1 |
| Juorio, AV | 1 |
| Sharpless, NS; Tabaddor, K; Wolfson, LI | 1 |
| Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM | 1 |
| Chadwick, D; Driver, MV; Jenner, P; Reynolds, EH; Trimble, M | 1 |
| Inagawa, T; Ishikawa, S; Uozumi, T | 1 |
| Fine, SA; Frohman, LA | 1 |
| Klawans, HL; Kramer, J; Nausieda, PA; Wiener, WJ | 1 |
| Davis, JM; Helgeson, E; Narasimhachari, N; Prakash, U | 1 |
| Farley, IJ; Hornykiewicz, O; Lee, T; Rajput, A; Seeman, P | 1 |
| Barkhatova, VP; Markova, ED | 1 |
| Marttila, R; Rinne, UK | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 2 |
| Bianchine, JR; Shaw, GM | 1 |
| Bronaugh, RL; Garver, DL; Rutledge, CO; Wenger, GR | 1 |
| Krishnamoorthy, MS; Sachdev, KK; Singh, N | 1 |
| Comoy, E; Lhermitte, F; Rosa, A | 1 |
| Algeri, S; Campanella, G; Cerletti, C; Dolfini, E; Jori, A; Rinaldi, F | 1 |
| Fleming, AM; Lenman, JA; Reid, A; Turnbull, MJ | 1 |
| Bunney, WE | 1 |
| Adams, RN; Delcore, R; Plotsky, PM; Strope, E; Wightman, RM | 1 |
| Baudry, M; Martres, MP; Schwartz, JC | 1 |
| Marttila, R; Rinne, UK; Sonninen, V | 2 |
| Delini-Stula, A; Maître, L; Waldmeier, PC | 1 |
| Deruaz, D; Gjessing, L; Greffe, J; Guilluy, R; Mathieu, P | 1 |
| Allen, N; Knopp, W | 1 |
| Bowers, MB; Extein, I; Roth, RH; Van Woert, M | 1 |
| Crowley, TJ; Hoehn, MM; Rutledge, CO | 1 |
| Dolphin, A; Jenner, P; Marsden, CD | 2 |
| Knopp, W; Messiha, FS | 1 |
| Buckingham, RL; Radulovacki, M | 1 |
| Chalmers, RJ; Johnson, RH; McLellan, DL | 1 |
| Corne, SJ; Goodwin, BL; Johnson, RD; Ruthven, CR; Sandler, M; Stephens, RJ | 1 |
| Bronaugh, RL; Hoehn, MM; MacMurtry, RJ; Rutledge, CO | 1 |
| Chase, TN; Shoulson, I | 1 |
| Krane, RJ; Murdock, MI; Olsson, CA; Sax, DS | 1 |
| Watson, E; Wilk, S | 1 |
| Schmidt, RT; Spehlmann, R; Stahl, SM | 1 |
| Fahn, S; Lane, E; Makadon, H; Prasad, AL; Snider, S | 1 |
| Kuschinsky, K | 1 |
| Cheng, LK; Fung, HL | 1 |
| Assael, BM; Bareggi, SR; Calderini, G; Collice, M; Morselli, PL; Porta, M; Rossanda, M; Selenati, A | 1 |
| Corsini, GU; Mangoni, A; Marrosu, F; Spissu, A | 1 |
| Messiha, F; Morgan, JP; Rivera-Calimlim, L; Sundaresan, PR; Trabert, N | 1 |
| Clayton, PT; Hyland, K | 1 |
| Aicardi, J; Goutières, F; Rondot, P; Ziegler, M | 1 |
| Heninger, GR; Kleber, HD; Kosten, TR; McDougle, CJ; Palumbo, JM; Price, LH | 1 |
| De Klippel, N; Deleu, D; Devrieze, A; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Borisenko, SA; Männistö, PT; Törnwall, M; Tuomainen, P; Tuominen, RK | 1 |
| Bjurling, P; Gillberg, PG; Långström, B; Miwa, S; Odano, I; Watanabe, Y; Yumoto, N | 1 |
| Hildebrand, J; Moussa, Z; Przedborski, S; Raftopoulos, C | 1 |
| Brannan, T; Martínez-Tica, J; Yahr, MD | 4 |
| Kaakkola, S; Männistö, PT; Tuomainen, P; Wurtman, RJ | 1 |
| Männistö, PT; Tuomainen, P; Tuominen, RK | 1 |
| De Klippel, N; Deleu, D; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Jenner, P; Marsden, CD; Rose, S | 3 |
| Baronti, F; Berrettini, WH; Brughitta, G; Chase, TN; Conant, KE; Davis, TL; Giuffra, M; Iadarola, MJ; Mouradian, MM | 1 |
| Cramer, H; Kuntzmann, F; Masson, H; Popescu, I; Strubel, D | 1 |
| Lindvall, B; Olsson, JE | 1 |
| Kuhn, W; Przuntek, H | 1 |
| Balottin, U; Borgatti, R; Lanzi, G; Zambrino, CA | 1 |
| Cano, J; Machado, A; Venero, JL | 2 |
| Carey, RJ | 1 |
| Cedarbaum, JM; Gauger, LL; Olanow, CW | 1 |
| Wikberg, T | 1 |
| Abbate, GM; Nieduzak, TR; Schmidt, CJ; Taylor, VL | 1 |
| Bodis-Wollner, I; Chung, E; Ghilardi, MF; Glover, A; Onofrj, M; Pasik, P; Samson, Y | 1 |
| Engel, JA; Hulthe, P; Johannessen, K; Pettersson, G | 1 |
| Bhardwaj, A; Brannan, T; Martinez-Tica, J; Weinberger, J; Yahr, M | 1 |
| De Herdt, P; Maitre, L; Waldmeier, PC | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Yahr, M | 1 |
| Di Paolo, T; Harnois, C | 1 |
| Bédard, PJ; Di Paolo, T; Rouillard, C | 1 |
| Ahlskog, JE; Bailey, PA; Bell, GN; Blexrud, MD; Carmichael, SW; Kelly, PJ; Stoddard, SL; Tyce, GM; van Heerden, JA; Windebank, AJ | 1 |
| Bonnet, JJ; Costentin, J; Vaugeois, JM | 1 |
| Dousa, MK; Muenter, MD; Tyce, GM | 1 |
| Cote, L; Dyrenfurth, I; Frantz, A; Mayeux, R; Stern, Y; Williams, JB | 1 |
| Bédard, P; Boucher, R; Daigle, M; Di Paolo, T | 1 |
| Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A | 1 |
| Andersen, K; Balldin, J; Gottfries, CG; Granérus, AK; Modigh, K; Svennerholm, L; Wallin, A | 1 |
| Barton, N; Burns, RS; Cohen, W; Fink, JK; Hallett, M; Lovenberg, W | 1 |
| Butler, IJ; Caskey, TC; Jankovic, J; Stout, JT | 1 |
| Hashimoto, T; Maekawa, N; Oishi, T; Sasaki, M; Tsuji, S | 1 |
| Araki, H; Kondo, T; Muramoto, S; Narabayashi, H; Nishi, K; Takubo, H | 1 |
| Dissing, IC; Gerdes, AM; Güttler, F; Lou, H; Lykkelund, C; Pakkenberg, H; Rasmussen, V | 1 |
| Kraus, P; Kuhn, W; Przuntek, H | 1 |
| Davoudi, H; Durso, R; Feldman, RG; Szabo, G | 1 |
| Fukuyama, Y; Kato, N; Sugie, H; Sugie, Y | 1 |
| Liu, DK | 2 |
| Aperia, A; Bertorello, A | 1 |
| Commissiong, JW | 2 |
| Cassel, G; Persson, SA; Sellström, A | 1 |
| Cohen, Y; el Gemayel, G; Jacquot, C; Prioux-Guyonneau, M; Trouvin, JH | 2 |
| Cooper, DR; Jenner, P; Marrel, C; Marsden, CD; Testa, B; van de Waterbeemd, H | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Leung, L; Yahr, M | 1 |
| Abeling, NG; Overmars, H; van Gennip, AH; Voûte, PA | 1 |
| Cannon-Spoor, E; Chuang, LW; Costa, E; Freed, WJ; Karoum, F; Wyatt, RJ | 1 |
| Domino, EF; Greenberg, HS; Hood, TW | 1 |
| Akiguchi, I; Itoh, H; Kameyama, M; Nakamura, S; Yamao, S | 1 |
| Byer, DE; Danielson, DR; Messick, JM; Rorie, DK; Tyce, GM; Yaksh, TL | 1 |
| Bankiewicz, KS; Chiueh, CC; Doppman, JL; Jacobowitz, DM; Kopin, IJ; Oldfield, EH | 1 |
| Harvey, NS | 1 |
| Aoki, S; Inukai, K; Kobayashi, M; Koshikawa, N; Sakurai, M | 1 |
| Artal, R; Barnes, RB; Lobo, RA | 1 |
| Algeri, S; Olgiati, VR; Stramentinoli, G | 1 |
| Portin, R; Rinne, UK | 1 |
| Globus, M; Melamed, E; Rosenthal, J; Uzzan, A | 1 |
| Aizenstein, ML; de-Lucia, R; Scavone, C; Steinschreiber, S | 1 |
| Hietala, J; Koulu, M; Scheinin, M; Syvälahti, E | 1 |
| Rorie, DK; Tyce, GM | 1 |
| Bermejo Pareja, F; de Yébenes, JG; Martinez-Martin, P; Muradas, V | 1 |
| Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
| Eplov, L; Nielsen, M; Scheel-Krüger, J | 1 |
| Kohsaka, M; Mori, A; Takeuchi, H | 1 |
| Barbour, P; Fahn, S; Prockop, L | 1 |
| Korf, J; Lakke, JP; Nienhuis, RJ; Schut, D; van Praag, HM | 1 |
| McDowell, FH; Sweet, RD | 1 |
| Hefti, F; Liebman, J; Melamed, E; Schlosberg, AJ; Wurtman, RJ | 1 |
| Lindén, IB | 1 |
| Haracz, JL | 1 |
| Jackson, DM; Miller, LP; Walters, JR | 1 |
| Feenstra, MG; Goedemoed, JH; Horn, AS; Rollema, H | 1 |
| Kikuchi, T; Watanabe, H; Watanabe, K | 1 |
| Colucci d'Amato, C; Cristillo, A; Puccini, A; Vizioli, R | 1 |
| Saeed Dar, M; Wooles, WR | 1 |
| Ito, M; Mikawa, H; Okuno, T; Osumi, Y | 1 |
| Calne, DB; Ebert, MH; Eisler, T; Kopin, IJ; Krebs, H; Lake, CR; Murphy, DL; Nelson, R; Teräväinen, H; Weise, V; Whetzel, N | 1 |
| Gabreëls, FJ; Jongen, PJ; Renier, WO | 1 |
| Gamaleia, NB | 1 |
| MacDonald, E; Rekonen, M; Riekkinen, PJ; Soininen, H | 1 |
| Bistolaki, E; Hadjikonstantinou, M; Markianos, M | 1 |
| Burns, RS; Chiueh, CC; Ebert, MH; Jacobowitz, DM; Kopin, IJ; Markey, SP | 1 |
| Watanabe, Y | 1 |
| Boespflug, O; Demeocq, F; Guyon, A; Malpuech, G; Piton, A; Vanlieferinghen, P | 1 |
| Brown, JW; Kramarcy, NR; Thurmond, JB | 1 |
| Gooskens, RH; van Nieuwenhuizen, O; Westenberg, HG; Willemse, J | 1 |
| Hadjikonstantinou, M; Markianos, M | 1 |
| Jenner, P; Kelly, E; Kilpatrick, G; Lees, A; Marsden, CD; Rose, S; Rupniak, NM | 1 |
| Lobo, RA; Shoupe, D | 1 |
| Goetz, CG; Klawans, HL; Perlik, S | 1 |
| Cooper, DR; Fleminger, S; Hall, MD; Jenner, P; Marsden, CD; Rupniak, NM | 1 |
| Achilli, G; Algeri, S; Perego, C; Ponzio, F; Rinaldi, G | 1 |
| Agid, Y; Bokobza, B; Javoy-Agid, F; Ruberg, M; Scatton, B | 1 |
| Amaral, R; Cunha, L; Dinis, M; Gonçalves, AF; Oliveira, C | 1 |
| Bird, ED; Langlais, PJ; McEntee, WJ | 1 |
| Fahn, S; Reches, A | 1 |
| Alsasua, A; Arias, J; Arias, JI; Durán Sacristán, H; Durán, M; Estebánez, E; García de Jalón, PD; López-Sánchez, ML | 1 |
| Hadjikonstantinou, M; Markianos, M; Sfagos, C | 1 |
| Bierer, DW; Quebbemann, AJ | 1 |
| Chandra, SV; Shukla, GS | 1 |
| Lee, T; Teo, WL; Wong, PT | 1 |
| Kaakkola, S; Kask, A; Männistö, PT; Törnwall, M; Tuomainen, P | 1 |
| Lima, L; Urbina, M | 1 |
| Ishikawa, A; Miyatake, T | 1 |
| Abe, T; Saheki, M; Takahashi, S; Tohgi, H; Tsukamoto, Y; Yamazaki, K | 1 |
| DeMaggio, AJ; Juneau, PL; LeWitt, PA; Loeffler, DA; Matson, WR; Milbury, PE | 1 |
| Bankiewicz, KS; Finberg, JP; Goldstein, DS; Kopin, IJ; Wang, J | 1 |
| Chen, CF; Hsieh, CC; Hsieh, MT; Peng, WH; Su, SH; Tsai, HY | 1 |
| Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J | 1 |
| Hashiguti, H; Ikeda, T; Maruyama, W; Nakahara, D; Naoi, M | 1 |
| Koitabashi, T; Koshiro, A; Sato, S | 1 |
| Da Prada, M; Napolitano, A; Zürcher, G | 1 |
| Kawai, H; Mitsui, T; Miyata, M; Saito, S; Sakoda, S | 1 |
| Carey, RJ; Dai, H; Huston, JP; Pinheiro-Carrera, M; Tomaz, C | 2 |
| Carey, RJ; Huston, JP; Pinheiro-Carrera, M; Tomaz, C | 1 |
| Chutorian, AM; Levine, RA; Naini, AB; Nygaard, TG; Waran, SP | 1 |
| Ikawa, K; Kaneno, S; Toru, M; Watanabe, A | 1 |
| Chang, LG; Gibb, WR; Hornykiewicz, O; Kish, S; Rajput, AH; Shannak, KS; Zhong, XH | 1 |
| Gayrard, V; Malpaux, B; Thiéry, JC; Tillet, Y | 1 |
| De Klippel, N; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Betto, P; Meneguz, A; Ricciarello, G | 1 |
| Bennett, JP; Parker, WD; Smith, TS | 1 |
| Asanuma, M; Kawada, Y; Kondo, Y; Mori, A; Ogawa, N; Yamamoto, M | 1 |
| Illi, A; Keränen, T; Myllylä, VV; Sotaniemi, KA; Suominen, K | 1 |
| Calne, DB; Galloway, MP; Levine, RA; Nygaard, TG; Snow, BJ; Takahashi, H | 1 |
| Hossain, MA; Weiner, N | 1 |
| Kuchel, OG; Shigetomi, S | 1 |
| LeWitt, PA | 1 |
| Da Prada, M; Dingemanse, J; Zürcher, G | 1 |
| Baraldo, M; Benetello, P; Furlanut, M; Hassan, E; Zara, G | 1 |
| Gordin, A; Harjola, VP; Karlsson, M; Keränen, T; Korpela, K; Pentikäinen, PJ; Rita, H; Seppälä, L; Wikberg, T | 1 |
| Cohen, G; DiRocco, A; Merchant, CA; Molinari, S; Moros, D; Mytilineou, C; Yahr, MD | 1 |
| O'Connell, MT; Patsalos, PN; Quinn, NP; Wenning, GK | 1 |
| Fernandes, MH; Pestana, M; Pinto-do-O, PC; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Rinne, UK; Ruottinen, HM | 1 |
| Chen, CF; Ho, YF; Hsieh, MT; Peng, WH; Wu, CR | 1 |
| Dethy, S; Goldman, S; Hildebrand, J; Laute, MA; Naini, AB; Przedborski, S; Raftopoulos, C | 1 |
| Maruyama, W; Naoi, M; Narabayashi, H | 1 |
| Ichikawa, M; Matsuyama, K; Nakashima, M; Nakashima, MN; Sakurai, M; Sasaki, H; Zhao, MF | 1 |
| Andre, MH; Bruguerolle, B; Grignon, S | 1 |
| Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J | 1 |
| Brannan, T; Prikhojan, A; Yahr, MD | 1 |
| Bowers, MB | 1 |
| Damhaut, P; Dethy, S; Goldman, S; Hildebrand, J; Laute, MA; Van Blercom, N | 1 |
| Antkiewicz-Michaluk, L; Krygowska-Wajs, A; Romańska, I; Szczudlik, A; Vetulani, J | 1 |
| Browne, TR; Durso, R; Evans, BA; Evans, JE; Handler, JS; Jennings, D; Josephs, E; Szabo, GK | 1 |
| Biaggioni, I; Butler, IJ; Hyland, K; Maller, A; Milstien, S | 1 |
| Bencsics, C; Kang, UJ; Wachtel, SR | 1 |
| Matsuishi, T; Shoji, H; Yamada, S; Zhou, G | 1 |
| Baldaia, J; Faria, MS; Guerra, LE; Oliveira, JG; Pestana, M; Santos, A; Soares-da-Silva, P | 1 |
| Budygin, EA; Gaĭnetdinov, RR; Mannisto, PT; Raevskiĭ, KS | 1 |
| Bankiewicz, K; Finberg, JP; Goldstein, DS; Harvey-White, J; Kopin, IJ; Wang, J | 1 |
| Myers, CS; Wagner, GC; Witten, M; Yu, YL | 1 |
| Hashitani, T; Kumazaki, M; Mizukawa, K; Nishino, H | 1 |
| Jaskowski, P; Kömpf, D; Moser, A; Siebecker, F; Vieregge, P | 1 |
| Cheng, FC; Chia, LG; Dryhurst, G; Kuo, JS | 1 |
| Brannan, T; Martínez-Tica, J; Prikhojan, A; Yahr, MD | 1 |
| Calne, DB; Caselli, RJ; Forno, LS; Hornykiewicz, O; Howard, FM; Kish, SJ; Maraganore, DM; Muenter, MD; Okazaki, H; Snow, BJ | 1 |
| Guerra, L; Jardim, H; Pestana, M; Serrão, P; Soares-da-Silva, P | 1 |
| Bjurling, P; Hartvig, P; Långström, B; Lindner, KJ; Ljungström, A; Tedroff, J | 1 |
| Ebinger, G; Izurieta-Sánchez, P; Michotte, Y; Sarre, S | 1 |
| Afonso, C; Guerra, L; Jardim, H; Pestana, M; Santos, N; Serrão, P; Soares-da-Silva, P | 1 |
| Chen, CF; Chueh, FS; Chueh, FY; Hsieh, MT; Lin, MT; Lin, SM | 1 |
| Mathangi, DC; Mohan, V; Namasivayam, A | 1 |
| Arnold, LA; Camp, DM; Hyland, K; Juneau, PL; LeWitt, PA; Loeffler, DA | 1 |
| Damhaut, P; Dethy, S; Goldman, S; Laute, MA | 1 |
| Halladay, AK; Myers, CS; Wagner, GC; Widmer, DA | 1 |
| Gainetdinov, R; Huotari, M; Männistö, PT | 1 |
| Kannari, K; Maeda, T; Matsunaga, M; Suda, T; Tanaka, H; Tomiyama, M | 1 |
| Alessandrì, MG; Bassi, L; Corsini, GU; Ferrucci, M; Fornai, F; Giorgi, FS | 1 |
| Doroshenko, EM; Etingof, RN; Lavrikova, EV; Pozdeyev, NV | 1 |
| Iacono, RP; Nahab, FB; Nahab, FH | 1 |
| Peng, Y; Shui, H; Tsai, Y; Wu, R | 1 |
| Fitzgerald, RS; Shirahata, M; Wang, HY | 1 |
| Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA | 1 |
| Bräutigam, C; Hoffman, GF; Hyland, K; Knust, A; Sharma, RK; Wevers, RA | 1 |
| Abeling, NG; Barth, PG; Bräutigam, C; Fiumara, A; Hoffmann, GF; Jaeken, J; Knust, A; van Gennip, AH; Wevers, RA | 1 |
| Browne, TR; Durso, R; Evans, B; Evans, JE; Fernandez, HH; Josephs, E; Szabo, G | 1 |
| Asanuma, M; Ogawa, N; Tanaka, K | 1 |
| Maruyama, W; Naoi, M; Strolin-Benedetti, M | 1 |
| DeJesus, OT; Stein, TD | 1 |
| Guimarães, JT; Pestana, M; Serrão, P; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Jenner, P; Rose, S; Treseder, SA | 1 |
| Chang, CK; Cheng, JT; Chi, TC; Lee, JJ; Liu, IM; Yu, HJ | 1 |
| Hainzl, D; Loureiro, AI; Parada, A; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Bettencourt, P; Cerqueira-Gomes, M; Correia, F; Ferreira, A; Martins, L; Pestana, M; Serrão, P; Soares-Da-Silva, P | 1 |
| Ferger, B; Schmidt, N; Schulz, JB; Teismann, P; Xia, XG | 1 |
| Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T | 1 |
| Buhmann, C; Oechsner, M; Strauss, J; Stuerenburg, HJ | 1 |
| Forsberg, M; Gogos, JA; Huotari, M; Hyttinen, J; Karayiorgou, M; Koponen, O; Männistö, PT; Raasmaja, A | 1 |
| Cimini, MG; Haas, JV; Nichols, NF; Staton, BA; Svensson, KA; Tedroff, J | 1 |
| Caudle, WM; Miller, GW; Reverón, ME; Tillerson, JL | 1 |
| Archer, T; Fredriksson, A | 1 |
| Gu, SD; Sun, XF; Wang, W; Zhao, DZ | 1 |
| Bergquist, F; Niazi Shahabi, H; Nissbrandt, H | 1 |
| Iida, Y; Saji, H; Shimazu, S; Takahata, K; Tamashiro, A; Yoneda, F | 1 |
| Jähnel, M | 1 |
| Antkiewicz-Michaluk, L; Herman, ZS; Obuchowicz, E; Romańska, I | 1 |
| Dziubina, A; Gołembiowska, K | 3 |
| Mathangi, DC; Namasivayam, A | 1 |
| Schmidt, WJ; Srinivasan, J | 1 |
| Ben Shachar, D; Stephenson, G; Youdim, MB | 1 |
| Gluck, MR; Granson, H; Santana, LA; Yahr, MD | 1 |
| Gispen-de Wied, CC; Kahn, RS; Kemner, C; Oranje, B; Verbaten, MN; Westenberg, HG | 2 |
| Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Sziray, N | 1 |
| Ogawa, N; Tanaka, K | 1 |
| Birk Møller, L; Diepold, K; Güttler, F; Hougaard, P; Romstad, A; Rostasy, K; Schütz, B; Wilken, B | 1 |
| Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Ogawa, N; Shimizu, M; Tanaka, K | 1 |
| Bezard, E; Bioulac, B; Boraud, T; Gross, CE; Harnack, D; Klitgaard, H; Kupsch, A; Meissner, W; Morgenstern, R; Ravenscroft, P; Reese, R | 1 |
| Arai, A; Baba, M; Kannari, K; Shen, H; Tomiyama, M | 1 |
| Adachi, K; Kondo, T; Kusumoto, H; Miwa, H; Shimazu, S | 1 |
| Cooper, JD; Davies, MI; Heppert, KE; Lunte, SM | 1 |
| Geurtz, PB; Verbeek, MM; Wevers, RA; Willemsen, MA | 1 |
| Gacsalyi, I; Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Megyeri, K; Sziray, N | 1 |
| Arrúe, A; Grandoso, L; Hernández, RM; Linazasoro, G; Manuel, I; Orive, G; Pedraz, JL; Ponce, S; Rodríguez, A; Rodríguez-Puertas, R; Ruiz-Ortega, JA; Ugedo, L; Ulibarri, I; Zumárraga, M | 1 |
| Kanazawa, M; Kitani, Y; Kohno, Y; Ogawa, A; Shintaku, H; Takayanagi, M | 1 |
| Davidson, DF; Grosset, D; Grosset, K | 1 |
| Barbanoj, M; Kulisevsky, J; Pérez, V; Rodríguez-Alvarez, J; Rubio, A; Sosti, V | 1 |
| Buck, K; Ferger, B | 1 |
| Artuch, R; Briones, P; Carrilho, I; Duarte, S; Garcia-Cazorla, A; Garesse, R; Montoya, J; Nascimento, A; Ormazabal, A; Pineda, M; Sala-Castellvi, P; Serrano, M | 1 |
| Antonelli, T; Cassano, T; Cuomo, V; Dipasquale, P; Ferraro, L; Gaetani, S; Giuffrida, A; Laconca, L; Macheda, T; Morgese, MG | 1 |
| Dziubina, A; Gołembiowska, K; Kamińska, K; Kowalska, M | 1 |
| Darvas, M; Palmiter, RD | 1 |
| Butler, IJ; Clement-Cormier, YC; Seifert, WE; Wilner, KD | 1 |
| Fukumura, T; Hosoi, R; Inoue, O; Nakao, R; Okada, M; Suzuki, K; Zhang, MR | 1 |
| Andersen, ML; Barnabé, GF; Dombrowski, PA; Lima, MM; Reksidler, AB; Tufik, S; Vital, MA | 1 |
| Aeby, A; Blau, N; Burlina, A; de Klerk, JB; de Lonlay, P; de Rijk-van Andel, JF; Donati, MA; Geurtz, B; Grattan-Smith, PJ; Haeussler, M; Hoffmann, GF; Jung, H; Kamsteeg, EJ; Kok, F; Leuzzi, V; Megarbane, A; Monaghan, H; Renier, WO; Rondot, P; Ryan, MM; Seeger, J; Smeitink, JA; Steenbergen-Spanjers, GC; van der Knaap, MS; Verbeek, MM; Wassmer, E; Weschke, B; Wevers, RA; Wijburg, FA; Wilcken, B; Willemsen, MA; Zafeiriou, DI | 1 |
| Borah, A; Mohanakumar, KP | 1 |
| Allen, E; Carlson, KM; Cavanaugh, JE; Zigmond, MJ | 1 |
| Armstrong, J; Artuch, R; Barredo-Valderrama, E; Campistol, J; Castro de Castro, P; Cormand, B; Garcia-Cazorla, A; Ormazabal, A; Serrano, M; Toma, C | 1 |
| Birbeck, JA; Bosse, KE; Colombo, ML; France, MM; Maina, FK; Mathews, TA; Roberts, JJ | 1 |
| Ansorge, MS; Esposito, E; Gingrich, JA; Gray, N; Moore, H; Morelli, E; Rebello, TJ; Steele, K | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Ain, NM; Fakurazi, S; Hussein, MZ; Hussein-Al-Ali, SH; Kura, AU | 1 |
| Li, B; Li, Y; Sun, Y; Wu, Y; Yang, J; Yu, J | 1 |
| Deng, M; Fang, Y; Huang, L; Li, L; Zhang, S | 1 |
| Di Paolo, T; Grégoire, L; Morin, N; Morissette, M | 1 |
| Aguirre, N; Barros-Miñones, L; Beitia, G; Goñi-Allo, B; Puerta, E; Suquia, V | 1 |
| Asahina, M; Higuchi, Y; Hirano, S; Kuwabara, S; Uchiyama, T; Yamamoto, T; Yamanaka, Y | 1 |
| Cerroni, R; D'Angelo, V; Fedele, E; Galati, S; Hainsworth, AH; Liguori, C; Olivola, E; Pierantozzi, M; Saviozzi, V; Stefani, A | 1 |
| Andersen, AD; Binzer, M; Blaabjerg, M; Gramsbergen, JBP; Kamal, A; Kjaer, TW; Stenager, E; Thagesen, H | 1 |
| Liu, J; Liu, X; Long, Y; Qin, C; Tong, L; Zheng, F; Zheng, Y | 1 |
| Doyle, KM; Kelly, JP; Moreira da Silva Santos, A | 1 |
| Akenine, U; Andersen, P; de Lange, ECM; Fredborg, W; Hillilä, C; Kivipelto, M; Lebedev, AV; Lindström, J; Lövdén, M; Nilsson, J; Spulber, G; van den Berg, DJ | 1 |
| Janssen, E; Nicolai, J; Oosterloo, M; Rubio-Gozalbo, E; van Gassen, K | 1 |
| Chahine, LM; Coffey, CS; Czech, C; Dukart, J; Dziadek, S; Foroud, T; Galasko, D; Gerken, T; Hutten, SJ; Kremer, T; Marek, K; Mollenhauer, B; Pagano, G; Poston, KL; Seibyl, J; Siebourg-Polster, J; Simuni, T; Staempfli, A; Tanner, CM; Taylor, KI; Toga, AW; Trenkwalder, C; Weintraub, D | 1 |
12 review(s) available for levodopa and homovanillic acid
| Article | Year |
|---|---|
[Modulation of dopaminergic receptor sensitivity in the central nervous system: important parameters in synaptic function regulation].
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior; Corpus Striatum; Dogs; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hypothermia; Levodopa; Memory; Mice; Opioid-Related Disorders; Parkinson Disease; Psychotic Disorders; Rats; Receptors, Dopamine; Sleep; Stereotyped Behavior; Substantia Nigra; Synapses; Synaptic Transmission | 1979 |
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cerebrovascular Disorders; Dopamine; Dysautonomia, Familial; Dystonia Musculorum Deformans; Hepatic Encephalopathy; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Movement Disorders; Multiple Sclerosis; Nervous System Diseases; Parkinson Disease; Phenylketonurias; Seizures; Spinal Cord Injuries; Torticollis; Tourette Syndrome | 1975 |
Amine precursors in neurologic disorders and the psychoses.
Topics: Acetylcholine; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Levodopa; Movement Disorders; Nerve Degeneration; Parkinson Disease; Psychoses, Substance-Induced; Psychotic Disorders | 1975 |
Brain nervous mechanisms involved in the so-called extra pyramidal motor and psychomotor disturbances.
Topics: Animals; Athetosis; Basal Ganglia Diseases; Brain; Brain Stem; Cats; Corpus Striatum; Disease Models, Animal; Dopa Decarboxylase; Dopamine; Extrapyramidal Tracts; Globus Pallidus; Haplorhini; Homovanillic Acid; Humans; Levodopa; Monoamine Oxidase; Neural Pathways; Olivary Nucleus; Psychomotor Disorders; Red Nucleus; Tyrosine 3-Monooxygenase | 1975 |
Brain monoamines in seizure mechanism (review).
Topics: Animals; Brain; Carbonic Anhydrase Inhibitors; Catecholamines; Child; Dextroamphetamine; Dopamine; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Iproniazid; Levodopa; Mice; Mice, Inbred Strains; Norepinephrine; Phenytoin; Rabbits; Rats; Reserpine; Seizures; Serotonin | 1977 |
Clinical pharmacokinetics of levodopa in parkinson's disease.
Topics: Carboxy-Lyases; Cardiovascular Diseases; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Gastric Mucosa; Gastrointestinal Diseases; Homovanillic Acid; Humans; Intestinal Absorption; Kinetics; Levodopa; Mental Disorders; Parkinson Disease; Pyridoxine; Stimulation, Chemical; Time Factors | 1976 |
[Dopa-sensitive dystonia].
Topics: Carbidopa; Child; Child, Preschool; Dystonia; Female; Follow-Up Studies; Homovanillic Acid; Humans; Infant; Levodopa; Male | 1992 |
Psychiatric disorders in parkinsonism. 1. Functional illnesses and personality.
Topics: Antidepressive Agents; Clozapine; Depressive Disorder; Dopamine; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Levodopa; Male; Mental Disorders; Nomifensine; Nortriptyline; Parkinson Disease; Personality; Psychotic Disorders; Serotonin; Tryptophan | 1986 |
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan | 1974 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors | 1974 |
[Biochemical bases of Parkinson disease].
Topics: Acetylcholine; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dopa Decarboxylase; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Selegiline; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1984 |
Presymptomatic and early detection in Huntington's disease.
Topics: Blood Platelets; Electrodiagnosis; Evoked Potentials; Eye Movements; gamma-Aminobutyric Acid; Genetic Carrier Screening; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Monoamine Oxidase; Movement; Neurologic Examination; Psychological Tests; Serotonin | 1980 |
16 trial(s) available for levodopa and homovanillic acid
| Article | Year |
|---|---|
Manipulation of cerebral monoamines in the treatment of human epilepsy: a pilot study.
Topics: Adult; Biogenic Amines; Brain Chemistry; Carbamazepine; Drug Evaluation; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Monoamine Oxidase Inhibitors; Pilot Projects; Serotonin; Tryptophan | 1978 |
Clinical and pharmacological evaluation of the effects of piribedil in patients with parkinsonism.
Topics: Aged; Antiparkinson Agents; Chorea; Clinical Trials as Topic; Confusion; Dioxoles; Dopamine; Drug Evaluation; Electromyography; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Motor Skills; Muscle Rigidity; Nausea; Parkinson Disease; Parkinson Disease, Postencephalitic; Piperazines; Pyrimidines; Tremor | 1975 |
Dopaminergic agonist effects on Parkinsonian clinical features and brain monamine metabolism.
Topics: Aged; Brain; Clinical Trials as Topic; Dopamine; Drug Evaluation; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Piperazines; Piribedil; Placebos; Serotonin | 1975 |
Conjugation of L-DOPA and its metabolites after oral and intravenous administration to Parkinsonian patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Aged; Clinical Trials as Topic; Dopamine; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Infusions, Parenteral; Levodopa; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Tritium | 1975 |
A double-blind evaluation of electroconvulsive therapy in Parkinson's disease with "on-off" phenomena.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease | 1987 |
Tetrahydrobiopterin and Parkinson's disease.
Topics: Adult; Antiparkinson Agents; Benserazide; Biopterins; Clinical Trials as Topic; Drug Combinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine | 1989 |
Deprenyl in Parkinson disease.
Topics: Adult; Aged; Carbidopa; Dopamine; Double-Blind Method; Drug Combinations; Epinephrine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease; Phenethylamines; Selegiline | 1981 |
Effect of entacapone, a COMT inhibitor, on the pharmacokinetics of levodopa and on cardiovascular responses in patients with Parkinson's disease.
Topics: Aged; Blood Pressure; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Hemodynamics; Homovanillic Acid; Humans; Levodopa; Middle Aged; Nitriles; Parkinson Disease; Pulse; Respiration | 1993 |
Human transplacental transfer of carbidopa/levodopa.
Topics: Antiparkinson Agents; Carbidopa; Dopamine; Female; Fetus; Homovanillic Acid; Humans; Levodopa; Maternal-Fetal Exchange; Parkinson Disease; Pregnancy; Tyrosine | 1995 |
Effect of one month's treatment with peripherally acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients.
Topics: Aged; Antiparkinson Agents; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine Agents; Double-Blind Method; Enzyme Inhibitors; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Tyrosine | 1996 |
The metabolism of L-DOPA and L-threo-3,4-dihydroxyphenylserine and their effects on monoamines in the human brain: analysis of the intraventricular fluid from parkinsonian patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antiparkinson Agents; Biogenic Monoamines; Cerebral Ventricles; Combined Modality Therapy; Dopamine; Droxidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease; Reference Values; Stereotaxic Techniques; Thalamus | 1996 |
Increase in salsolinol level in the cerebrospinal fluid of parkinsonian patients is related to dementia: advantage of a new high-performance liquid chromatography methodology.
Topics: Adult; Aged; Antiparkinson Agents; Chromatography, High Pressure Liquid; Dementia; Female; Homovanillic Acid; Humans; Isoquinolines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Tyrosine | 1997 |
Increasing dopaminergic activity: effects of L-dopa and bromocriptine on human sensory gating.
Topics: Acoustic Stimulation; Adult; Brain; Bromocriptine; Cross-Over Studies; Dopamine Agents; Dopamine Agonists; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Homovanillic Acid; Humans; Levodopa; Male; Prolactin; Sensory Deprivation; Time Factors | 2004 |
No effects of l-dopa and bromocriptine on psychophysiological parameters of human selective attention.
Topics: Adult; Antiparkinson Agents; Attention; Bromocriptine; Cross-Over Studies; Dopamine; Dopamine Agonists; Double-Blind Method; Electroencephalography; Electrooculography; Event-Related Potentials, P300; Homovanillic Acid; Humans; Levodopa; Male; Prolactin; Psychomotor Performance; Psychophysiology; Receptors, Dopamine D2 | 2006 |
Parkinson's disease: the effect of L-dopa therapy on urinary free catecholamines and metabolites.
Topics: Adolescent; Adult; Aged; Antiparkinson Agents; Catecholamines; Creatinine; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Metanephrine; Middle Aged; Norepinephrine; Normetanephrine; Parkinson Disease; Pheochromocytoma | 2007 |
Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial.
Topics: Aged; Body Mass Index; Brain; Cognition; Dopamine Agents; Double-Blind Method; Female; Homovanillic Acid; Humans; Learning; Levodopa; Magnetic Resonance Imaging; Male; Memory, Short-Term; Placebos | 2020 |
311 other study(ies) available for levodopa and homovanillic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The neurochemistry of Parkinson's disease: effect of L-dopa therapy.
Topics: Aged; Brain; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Monoamine Oxidase; Parkinson Disease; Tyrosine 3-Monooxygenase | 1975 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine | 1977 |
A disorder of biogenic amines in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Brain; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Liver; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Vanilmandelic Acid | 1978 |
The effect of simultaneous administration of 3,4-dihydroxyphenylpyruvic acid and L-dopa on the bioavailability of L-dopa in rat and mouse.
Topics: Animals; Biological Availability; Brain Chemistry; Dopamine; Drug Interactions; Homovanillic Acid; Levodopa; Male; Mice; Motor Activity; Phenylpyruvic Acids; Reserpine | 1979 |
Inhibition of guinea-pig brain tyrosine hydroxylase by catechols and biopterin.
Topics: Animals; Biopterins; Calcium; Catechols; Caudate Nucleus; Cyclic AMP; Dopamine; Guinea Pigs; Homovanillic Acid; Kinetics; Levodopa; Norepinephrine; Pteridines; Tyrosine 3-Monooxygenase | 1979 |
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Infant; Infant, Newborn; Lactates; Levodopa; Middle Aged; Neuroblastoma; Phenylethyl Alcohol | 1978 |
Levodopa in Huntingtons chorea.
Topics: Adult; Aged; Behavior; Drug Administration Schedule; Electroencephalography; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Levodopa; Long-Term Care; Male; Middle Aged; Probenecid | 1976 |
Effects of tetrahydropapaveroline on dopamine and 5-hydroxytryptamine metabolism in rat brain in vivo.
Topics: Animals; Brain; Dopamine; Fenclonine; Homovanillic Acid; Isoquinolines; Levodopa; Male; Papaverine; Rats; Serotonin | 1976 |
Levodopa and Huntington's chorea.
Topics: Adult; Female; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Pedigree; Serotonin | 1976 |
Rational approaches to the pharmacotherapy of chorea.
Topics: Acetylcholine; Chorea; Dopamine; Drug Evaluation; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Norepinephrine; Serotonin | 1976 |
Recent advances in the biochemical pharmacology of extrapyramidal movement disorders.
Topics: Animals; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Parkinson Disease; Receptors, Dopamine; Stereotyped Behavior; Synapses; Tranquilizing Agents | 1977 |
[Letter: Narcolepsy. Suppression of paradoxical sleep by L-dopa].
Topics: Catecholamines; Cyproterone; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Narcolepsy; Serotonin; Sleep, REM; Vanilmandelic Acid | 1976 |
Overnight sleep EEG and cerebrospinal fluid monoamines in seizures induced by movement.
Topics: Child; Electroencephalography; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Movement; Pedigree; Phenylacetates; Phenytoin; Seizures; Sleep; Sleep, REM | 1979 |
[Parkinson's disease: neuro-anatomical, biochemical and pharmicotherapeutic aspects].
Topics: Basal Ganglia; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Middle Aged; Neurotransmitter Agents; Parkinson Disease | 1975 |
Catecholamine and octopamine concentrations in brains of patients with Reye syndrome.
Topics: Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Hypothalamus; Levodopa; Octopamine; Reye Syndrome | 1977 |
Neurochemical investigations of the interaction of N,N-dimethyltryptamine with dopaminergic system in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Levodopa; Monoamine Oxidase; N,N-Dimethyltryptamine; Norepinephrine; Normetanephrine; Rats; Time Factors; Tryptamines; Tyramine | 1977 |
Effect of a catechol-O-methyl transferase inhibitor, U-0521, with levodopa administration.
Topics: Animals; Behavior, Animal; Brain; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Methyldopa; Propiophenones; Rats; Time Factors | 1979 |
gamma-Glutamyl DOPA and gamma-glutamyl dopamine: effect on plasma glucose levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Glucose; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Levodopa; Pancreas; Rats; Time Factors | 1979 |
Electromyographical and biochemical studies on mutant Han-Wistar rats with progressive spastic paresis.
Topics: Adenylyl Cyclases; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Electromyography; Female; Homovanillic Acid; Levodopa; Male; Mutation; Paresis; Rats; Serotonin | 1979 |
Effect of stress and L-DOPA administration on mouse striatal tyramine and homovanillic acid levels.
Topics: Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Levodopa; Male; Mice; Phenylacetates; Receptors, Dopamine; Stress, Physiological; Tyramine | 1979 |
Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders.
Topics: Adult; Aged; Cerebral Palsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Middle Aged; Movement Disorders; Multiple Sclerosis; Parkinson Disease; Phenylacetates | 1978 |
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Hepatolenticular Degeneration; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Movement Disorders; Parkinson Disease; Parkinson Disease, Postencephalitic; Serotonin; Tetrabenazine; Torticollis | 1977 |
[Cerebrospinal fluid amine metabolites and L-dopa in vegetative state patients (author's transl)].
Topics: Adult; Aged; Child; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Phenylacetates; Unconsciousness | 1978 |
Loss of central nervous system component of dopaminergic inhibition of prolactin secretion in patients with prolactin-secreting pituitary tumors.
Topics: Adult; Carbidopa; Dopamine; Female; Homovanillic Acid; Humans; Hypothalamo-Hypophyseal System; Levodopa; Male; Middle Aged; Pituitary Neoplasms; Prolactin | 1978 |
Paradoxial response to dopaminergic agents in parkinsonism.
Topics: Acetonitriles; Aged; Carbidopa; Ergolines; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Receptors, Dopamine | 1978 |
Simultaneous determination by GC-MS-SIM of o-, m-, p-hydroxyphenylacetic acid, 3:4-dihydroxyphenylacetic acid and homovanillic acid in biological samples using a common selected ion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, Gas; Homovanillic Acid; Humans; Levodopa; Mass Spectrometry; Methods; Phenylacetates | 1978 |
Receptor basis for dopaminergic supersensitivity in Parkinson's disease.
Topics: Adult; Aged; Apomorphine; Caudate Nucleus; Dopamine; Haloperidol; Homovanillic Acid; Humans; Levodopa; Middle Aged; Parkinson Disease; Putamen; Receptors, Dopamine; Synaptic Membranes | 1978 |
[Pathogenesis and treatment of torsion dystonia].
Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; Homovanillic Acid; Humans; Hydrazines; Jews; Levodopa; Norepinephrine; Vanilmandelic Acid | 1978 |
Brain dopamine receptor stimulation and the relief of Parkinsonism: relationship between bromocriptine and levodopa.
Topics: Benserazide; Brain; Bromocriptine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine | 1978 |
L-deprenyl treatment of on-off phenomena in Parkinson's disease.
Topics: Aged; Benserazide; Dopamine; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline; Vanilmandelic Acid | 1978 |
Effect of carbidopa on the metabolism of L-dopa in the pigtail monkey.
Topics: Animals; Carbidopa; Dopa Decarboxylase; Female; Haplorhini; Homovanillic Acid; Hydrazines; Lactates; Levodopa; Time Factors | 1976 |
Juvenile parkinsonism treated with levodopa.
Topics: Age Factors; Child; Child, Preschool; Drug Evaluation; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parkinson Disease; Serotonin | 1977 |
[Abnormal movements of patients with Parkinsonism treated with L-dopa and anomalies of dopamine metabolism].
Topics: Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA + RO 4-4602.
Topics: Benserazide; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Time Factors | 1977 |
Urinary monoamine metabolite excretion in disorders of movement. Effects of amantadine and levodopa.
Topics: Amantadine; Chorea; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methylhistamines; Middle Aged; Movement Disorders; Parkinson Disease; Phenylacetates; Tremor | 1977 |
Nonstriatal dopaminergic neurons: Section XI. Dopaminergic neurons and mental diseases: Introduction: dopaminergic neurons and mental diseases.
Topics: Apomorphine; Bromocriptine; Catecholamines; Depression; Dopamine; Homovanillic Acid; Humans; Levodopa; Mental Disorders; Neurons; Schizophrenia | 1977 |
Liquid chromatographic monitoring of CSF metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Rabbits; Rats; Serotonin | 1977 |
In vivo binding of 3H-pimozide in mouse striatum: effects of dopamine agonists and antagonists.
Topics: Animals; Apomorphine; Cerebellum; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; Haloperidol; Homovanillic Acid; Levodopa; Male; Mice; Pimozide; Receptors, Dopamine; Sulpiride | 1977 |
Brain dopamine turnover and the relief of parkinsonism.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Bromocriptine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parkinson Disease; Piperazines; Piribedil; Probenecid; Receptors, Dopamine | 1977 |
Preferential deamination of dopamine by an A type monoamine oxidase in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clorgyline; Corpus Striatum; Deamination; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Normetanephrine; Phenethylamines; Rats; Reserpine; Serotonin; Tyramine | 1976 |
N-Acetyl, 4-O-methyldopa, a major metabolite of L-4-O-methyldopa in man and rat.
Topics: Acetylation; Adult; Animals; Dopamine; Female; Homovanillic Acid; Humans; Isomerism; Lactates; Levodopa; Male; Methyldopa; Pyruvates; Rats; Species Specificity | 1976 |
Hereditary Parkinsonism-dystonia with sustained control by L-DOPA and anticholinergic medication.
Topics: Adolescent; Adult; Aged; Dopamine beta-Hydroxylase; Dystonia Musculorum Deformans; Female; Growth Hormone; Handwriting; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parkinson Disease; Pedigree; Prolactin; Reflex, Pupillary; Syndrome; Trihexyphenidyl | 1976 |
14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa.
Topics: Aged; Brain; Carbidopa; Carboxy-Lyases; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Sensory Receptor Cells | 1976 |
Dopamine correlates of neurological and psychological status in untreated Parkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Affect; Aged; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; MMPI; Parkinson Disease; Psychopathology | 1976 |
Noradrenaline synthesis from L-DOPA in rodents and its relationship to motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Rats; Reserpine; Time Factors | 1976 |
Comparison of short and long-lasting effects of pargyline on cerebral dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cisterna Magna; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Injections; Injections, Intravenous; Levodopa; Methyldopa; Monoamine Oxidase; Pargyline; Rats; Time Factors; Tyrosine | 1976 |
A study of endogenous dopamine metabolism in Gilles de la Tourette's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Epinephrine; Haloperidol; Homovanillic Acid; Humans; Imipramine; Levodopa; Male; Tourette Syndrome | 1976 |
The effects of reserpine, L-dopa and 5-hydroxytryptophan on 5-hydroxyindoleacetic and homovanillic acids in cerebrospinal fluid, behaviour and EEG in cats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cats; Electroencephalography; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Phenylacetates; Reserpine; Time Factors | 1976 |
Metatyramine as a dopaminergic agonist.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Dopamine; Drug Interactions; Exploratory Behavior; Homovanillic Acid; Levodopa; Motor Activity; Phenylacetates; Rats; Receptors, Drug; Reserpine; Tyramine; Tyrosine | 1975 |
Dopaminergic mechanisms in patients with extrapyramidal disease.
Topics: Animals; Biogenic Amines; Brain; Caffeine; Clonidine; Dopamine; Drug Evaluation; Drug Therapy, Combination; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parasympatholytics; Parkinson Disease; Piperazines; Piribedil; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Drug; Stimulation, Chemical | 1975 |
Effects of levodopa on the bladder outlet.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Ureter; Urinary Bladder; Urinary Bladder Neck Obstruction; Urination | 1975 |
Assessment of cerebrospinal fluid levels of dopamine metabolites by gas chromatography.
Topics: 3,4-Dihydroxyphenylacetic Acid; Chromatography, Gas; Dopamine; Homovanillic Acid; Levodopa; Parkinson Disease; Phenylacetates; Propionates | 1975 |
A pharmacologic study of the stiff-man syndrome. Correlation of clinical symptoms with urinary 3-methoxy-4-hydroxy-phenyl glycol excretion.
Topics: Diazepam; Glycine; Glycols; Homovanillic Acid; Humans; Levodopa; Male; Metanephrine; Methoxyhydroxyphenylglycol; Middle Aged; Muscle Rigidity; Normetanephrine; Physostigmine; Spasm; Syndrome; Vanilmandelic Acid | 1975 |
Normalization of brain serotonin by L-tryptophan in levodopa-treated rats.
Topics: Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Serotonin; Tryptophan | 1975 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
Effects of chronic oral administration on the disposition of laevodopa and its major metabolites in the plasma of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Catecholamines; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Time Factors; Vanilmandelic Acid | 1975 |
Homovanillic acid and 5-hydroxyindole-acetic acid in the csf of patients after a severe head injury. I. Lumbar csf concentration in chronic brain post-traumatic syndromes.
Topics: Adolescent; Adult; Brain Damage, Chronic; Child; Child, Preschool; Coma; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Phenylacetates | 1975 |
Proceedings: Biochemical evidence for the involvement of noradrenaline in motor activity produced by L-DOPA in rodents.
Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Mice; Motor Activity; Norepinephrine | 1975 |
Treatment of Sydenham's chorea with a combination of L-dopa and a peripheral dopa decarboxylase inhibitor.
Topics: Acute Disease; Adolescent; Carbidopa; Chorea; Drug Therapy, Combination; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Recurrence | 1975 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Metanephrine; Middle Aged; Normetanephrine; Parkinson Disease; Tyramine; Vanilmandelic Acid | 1975 |
Imipramine-mediated interference with levodopa absorption from the gastrointestinal tract in man.
Topics: Adult; Depression, Chemical; Dopamine; Gastric Juice; Homovanillic Acid; Humans; Imipramine; Intestinal Absorption; Levodopa; Male; Polyethylene Glycols; Vanilmandelic Acid | 1975 |
Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology.
Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dopa Decarboxylase; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Liver; Metabolism, Inborn Errors; Reference Values; Tyrosine | 1992 |
Dopaminergic responsivity during cocaine abstinence: a pilot study.
Topics: Adult; Carbidopa; Cocaine; Dopamine Agents; Drug Combinations; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Prolactin; Receptors, Dopamine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Biotransformation of L-dopa in striatum and substantia nigra of rats with a unilateral, nigrostriatal lesion: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthetics; Animals; Biotransformation; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1992 |
Effect of nitecapone and clorgyline, given intracerebro-ventricularly on L-dopa metabolism in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Catechols; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraventricular; Levodopa; Male; Pentanones; Prolactin; Rats; Rats, Wistar; Thyrotropin | 1992 |
Assessment of dopamine and its metabolites in the intracellular and extracellular compartments of the rat striatum after peripheral administration of L-[11C]dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Extracellular Space; Homovanillic Acid; Injections, Intravenous; Intracellular Fluid; Kinetics; Levodopa; Male; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Lack of changes in ventricular cerebrospinal fluid concentrations of homovanillic acid following acute challenge with levodopa.
Topics: Aged; Carbidopa; Cerebral Ventricles; Drug Combinations; Female; Homovanillic Acid; Humans; Hydrocephalus, Normal Pressure; Levodopa; Male; Middle Aged; Parkinson Disease | 1992 |
Catechol-O-methyltransferase inhibition increases striatal L-dopa and dopamine: an in vivo study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Nitrophenols; Rats; Rats, Inbred Strains; Tolcapone | 1992 |
Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Depression, Chemical; Dialysis; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraperitoneal; Levodopa; Male; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat.
Topics: Amidines; Animals; Benzophenones; Biogenic Monoamines; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Homovanillic Acid; Hypothalamus; Levodopa; Male; Methyldopa; Nitriles; Nitrophenols; Pyridones; Rats; Rats, Inbred Strains; Tolcapone | 1992 |
High-performance liquid chromatography with electrochemical detection for the determination of levodopa, catecholamines and their metabolites in rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Injections, Intraperitoneal; Levodopa; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Substantia Nigra | 1992 |
Peripheral pharmacokinetic handling and metabolism of L-dopa in the rat: the effect of route of administration and carbidopa pretreatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Aorta, Thoracic; Carbidopa; Chromatography, High Pressure Liquid; Homovanillic Acid; Injections, Intravenous; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1991 |
Opioid peptides in Parkinson's disease: effects of dopamine repletion.
Topics: Adult; Aged; Aged, 80 and over; Dopamine; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Homovanillic Acid; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Peptide Fragments | 1991 |
Somatostatin-like immunoreactivity in the cerebrospinal fluid of aged patients with Parkinson's disease. The effect of dopatherapy.
Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Cognition Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Parkinson Disease; Severity of Illness Index; Somatostatin | 1990 |
Monoamine metabolites and neuropeptides in patients with Parkinson's disease, Huntington's chorea, Shy-Drager syndrome, and torsion dystonia.
Topics: Dystonia Musculorum Deformans; Enkephalin, Methionine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Neuropeptides; Neurotransmitter Agents; Parkinson Disease; Shy-Drager Syndrome; Somatostatin | 1990 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPS, HIAA, and HVA levels of cerebrospinal fluid.
Topics: Carboxy-Lyases; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease; Selegiline | 1990 |
Consideration on two cases of dystonia-parkinsonism.
Topics: Carbidopa; Child; Dystonia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease, Secondary | 1991 |
Age effects on monoamine turnover of the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydrazines; In Vitro Techniques; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1991 |
Effect of dietary protein on striatal dopamine formation following L-dopa administration: an in vivo study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dialysis; Dietary Proteins; Dopamine; Extracellular Space; Homovanillic Acid; In Vitro Techniques; Levodopa; Male; Rats; Rats, Inbred Strains | 1991 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effect in Parkinson's disease.
Topics: Aged; Carbidopa; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1991 |
Simultaneous determination of levodopa, its main metabolites and carbidopa in plasma by liquid chromatography.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, High Pressure Liquid; Chromatography, Liquid; Freeze Drying; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Levodopa; Solutions; Tyrosine | 1991 |
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Anti-Arrhythmia Agents; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Homovanillic Acid; Levodopa; Male; Nomifensine; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Stereoisomerism; Time Factors | 1991 |
Effect of long-term L-dopa administration on striatal extracellular dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Acetyl-levo-carnitine protects against MPTP-induced parkinsonism in primates.
Topics: Acetylcarnitine; Animals; Carbidopa; Caudate Nucleus; Electroretinography; Female; Homovanillic Acid; Immunohistochemistry; Levodopa; Macaca fascicularis; Male; MPTP Poisoning; Parkinson Disease, Secondary; Substantia Nigra | 1991 |
Effect of amperozide on the synthesis and turnover of monoamines in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Levodopa; Male; Methyltyrosines; Norepinephrine; Piperazines; Psychotropic Drugs; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Striatal L-dopa metabolism studied in vivo in rats with nigrostriatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1990 |
Effects of the COMT inhibitor, CGP 28014, on plasma homovanillic acid and O-methylation of exogenous L-dopa in the rat.
Topics: Amidines; Animals; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Electrochemistry; Female; Homovanillic Acid; Levodopa; Pyridones; Rats; Rats, Inbred Strains; Tyrosine | 1990 |
In vivo studies of striatal dopamine release and metabolism following administration of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission | 1990 |
Decreased dopamine in the retinas of patients with Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Retina | 1990 |
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone | 1990 |
Adrenal medullary transplantation into the brain for treatment of Parkinson's disease: clinical outcome and neurochemical studies.
Topics: Activities of Daily Living; Adrenal Medulla; Adult; Caudate Nucleus; Cells, Cultured; Dopamine; Epinephrine; Follow-Up Studies; Homovanillic Acid; Humans; Hydrocortisone; Levodopa; Male; Middle Aged; Movement Disorders; Nerve Growth Factors; Norepinephrine; Parkinson Disease | 1990 |
Relationship between the effects of dexamphetamine on locomotion and on striatal [3H]GBR 12783 binding in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Antagonists; Homovanillic Acid; Levodopa; Male; Mice; Motor Activity; Piperazines; Reserpine | 1990 |
MAO and L-dopa treatment of Parkinson's disease.
Topics: Aged; Carbidopa; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase; Parkinson Disease | 1990 |
Clinical and biochemical features of depression in Parkinson's disease.
Topics: Aged; Depressive Disorder; Dexamethasone; Growth Hormone; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease; Prolactin; Psychomotor Performance; Self Concept; Thyrotropin-Releasing Hormone | 1986 |
Long-term effects of MPTP on central and peripheral catecholamine and indoleamine concentrations in monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Bromocriptine; Catecholamines; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Macaca fascicularis; Parkinson Disease, Secondary; Prolactin; Pyridines | 1986 |
Neurotransmitter therapy and diet in malignant phenylketonuria.
Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias | 1987 |
Dystonia with marked diurnal variation associated with biopterin deficiency.
Topics: Adolescent; Adult; Biopterins; Carbidopa; Child; Child, Preschool; Circadian Rhythm; Drug Combinations; Dystonia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Neopterin; Sibling Relations | 1988 |
Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters.
Topics: Carbidopa; Catecholamines; Child; Child, Preschool; Fluphenazine; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syndrome; Levodopa; Male; Methoxyhydroxyphenylglycol; Movement Disorders; Self Mutilation; Tetrabenazine | 1988 |
[A study on catecholamine metabolites in CSF in a patient with progressive dystonia with marked diurnal fluctuation].
Topics: Adolescent; Catecholamines; Circadian Rhythm; Dystonia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol | 1988 |
Unresponsiveness to L-DOPA in parkinsonian patients: a study of homovanillic acid concentration in the cerebrospinal fluid.
Topics: Aged; Biomarkers; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Parkinson Disease | 1989 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Activity; Parkinson Disease; Phenethylamines; Selegiline | 1989 |
Magnitude of response to levodopa in Parkinson disease as it relates to peripheral and central measurements of levodopa and associated metabolites.
Topics: Aged; Carbidopa; Drug Combinations; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1989 |
A patient with infantile spasms and low homovanillic acid levels in cerebrospinal fluid: L-dopa dependent seizures?
Topics: Dopamine; Female; Homovanillic Acid; Humans; Infant; Levodopa; Pyridoxine; Spasms, Infantile | 1989 |
[The concentration of homovanillic acid and leucine-enkephalin in the lumbar CSF of patients with Parkinson's disease before and after madopar treatment].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Drug Combinations; Enkephalin, Leucine; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1989 |
Effect of L-DOPA, dopamine, dihydroxyphenyl acetic acid and homovanillic acid on Na,K-ATPase activity in rat proximal tubule segments.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Kidney Tubules, Proximal; Levodopa; Male; Phenylacetates; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1987 |
The synthesis and metabolism of catecholamines in the spinal cord of the rat after acute and chronic transections.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Cordotomy; Dopamine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homovanillic Acid; Levodopa; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord | 1985 |
Acute cyanide intoxication and central transmitter systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Apomorphine; Brain; Cyanides; Cyclic GMP; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Spiperone | 1985 |
Re-evaluation of the L-dopa loading effect on dopamine metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
Dopaminergic metabolism in various rat brain areas after L-dopa loading.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Methoxytryptamine; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Hippocampus; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains | 1986 |
L-dopa esters as potential prodrugs: effect on brain concentration of dopamine metabolites in reserpinized mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Mice; Olfactory Bulb; Pharmaceutical Preparations; Prodrugs; Reserpine | 1987 |
Intracerebral dialysis monitoring of striatal dopamine release and metabolism in response to L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains | 1989 |
Biochemical monitoring of children with neuroblastoma.
Topics: Aminoisobutyric Acids; Child; Cystathionine; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Levodopa; Monitoring, Physiologic; Neuroblastoma; Norepinephrine; Prognosis | 1986 |
D-dopa and L-dopa similarly elevate brain dopamine and produce turning behavior in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Cerebral Ventricles; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Structure-Activity Relationship | 1988 |
The effect of carbidopa on plasma and muscle levels of L-dopa, dopamine, and their metabolites following L-dopa administration to rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Synergism; Homovanillic Acid; Levodopa; Muscles; Rats; Tyrosine | 1988 |
Possible treatment of Parkinson's disease with intrathecal medication in the MPTP model.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Homovanillic Acid; Infusion Pumps; Injections, Spinal; Levodopa; Parkinson Disease, Secondary; Pyridines; Time Factors | 1988 |
[Levodopa therapy in a patient with ALS-dementia complex].
Topics: Amyotrophic Lateral Sclerosis; Dementia; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged | 1987 |
Amine sulfate formation in the central nervous system.
Topics: Animals; Arylsulfotransferase; Brain; Carbidopa; Chlorocebus aethiops; Contraceptives, Oral, Combined; Dopamine; Homovanillic Acid; Humans; Levodopa; Norepinephrine; Serotonin; Sulfurtransferases | 1986 |
Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Brain; Brain Chemistry; Carbidopa; Carotid Artery, Internal; Disease Models, Animal; Dominance, Cerebral; Dopamine; Homovanillic Acid; Injections, Intra-Arterial; Levodopa; Macaca fascicularis; Movement; Neurons; Parkinson Disease, Secondary; Pyridines | 1986 |
Monitoring of dopamine metabolism by in vivo voltammetry and high performance liquid chromatography in L-dopa-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechols; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Norepinephrine; Oxidation-Reduction; Proteins; Rats | 1987 |
Peripheral dopamine metabolism in polycystic ovary syndrome.
Topics: Adult; Carbidopa; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Methoxyhydroxyphenylglycol; Norepinephrine; Polycystic Ovary Syndrome | 1987 |
Biochemical and behavioural indices of striatal dopaminergic activity after 6-methyltetrahydropterin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Levodopa; Male; Neurons; Pterins; Rats; Rats, Inbred Strains; Reserpine | 1987 |
Predictive factors for cognitive deterioration and dementia in Parkinson's disease.
Topics: Cognition Disorders; Dementia; Electroencephalography; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Prognosis | 1987 |
Biochemical effects of chronic L-dopa treatment in rats: implications for emergence of tolerance phenomena in patients with Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Brain; Dopamine; Drug Administration Schedule; Drug Tolerance; Homovanillic Acid; Humans; Levodopa; Male; Parkinson Disease; Rats | 1987 |
Differential changes in dopaminergic receptor sensitivity induced by agonist drugs.
Topics: Animals; Apomorphine; Benserazide; Brain Chemistry; Catalepsy; Drug Therapy, Combination; Haloperidol; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred Strains; Receptors, Dopamine | 1985 |
Neuroendocrine aspects in monitoring of dopaminergic drugs in man.
Topics: Apomorphine; Bromocriptine; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Metoclopramide; Monitoring, Physiologic; Neurosecretory Systems; Prolactin; Receptors, Dopamine; Schizophrenia; Selegiline; Time Factors | 1985 |
Metabolism of catecholamines in the developing spinal cord of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Fetus; Homovanillic Acid; Levodopa; Norepinephrine; Rats; Spinal Cord; Tissue Distribution | 1985 |
Effects of L-dopa and L-tyrosine on release of free and conjugated dopamine, homovanillic acid and dihydroxyphenylacetic acid from slices of rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Corpus Striatum; Dopamine; Homovanillic Acid; In Vitro Techniques; Levodopa; Male; Phenethylamines; Phenylacetates; Potassium; Rats; Tyrosine | 1985 |
Carbidopa dosage modifies L-dopa induced side effects and blood levels of L-dopa and other amino acids in advanced parkinsonism.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan; Tyrosine | 1985 |
Protriptyline induced inhibition of the in vivo 3H-noradrenaline synthesis from 3H-L-dopa in the rat brain.
Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Brain Chemistry; Catecholamines; Cerebral Ventricles; Chromatography, Ion Exchange; Dibenzocycloheptenes; Homovanillic Acid; Injections; Levodopa; Male; Norepinephrine; Propylamines; Rats; Specific Pathogen-Free Organisms; Spectrometry, Fluorescence; Time Factors; Tritium; Tyrosine | 1974 |
[Effect of catecholamines and their analogs on the electric activity of a giant neuron identified in the subesophageal ganglia of the giant african snail (Achatina fulica Ferussac)].
Topics: Action Potentials; Animals; Catecholamines; Dopamine; Epinephrine; Homovanillic Acid; Levodopa; Mandelic Acids; Methoxyhydroxyphenylglycol; Neural Conduction; Neurons; Norepinephrine; Normetanephrine; Octopamine; Phenylalanine; Snails; Structure-Activity Relationship; Synephrine; Tyramine; Tyrosine | 1974 |
Clinical studies of dopaminergic mechanisms.
Topics: Antiparkinson Agents; Dioxoles; Dopamine; Drug Evaluation; Haloperidol; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Piperidines; Probenecid; Pyrimidines | 1974 |
Homovanillic acid: entry rate kinetics for transfer from plasma to cerebrospinal fluid.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Carbon Radioisotopes; Dogs; Homovanillic Acid; Injections, Intravenous; Kinetics; Levodopa; Mannitol; Phenylacetates | 1974 |
Parkinson's disease and amine metabolites in cerebrospinal fluid: implications for L-Dopa therapy.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Depression, Chemical; Dopa Decarboxylase; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Stimulation, Chemical; Time Factors | 1974 |
Plasma dopa concentrations and the "on-off" effect after chronic treatment of Parkinson's disease.
Topics: Dietary Proteins; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Movement Disorders; Parkinson Disease | 1974 |
Serotonergic neurones are not involved in action of L-dopa in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Stem; Disease Models, Animal; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Levodopa; Parkinson Disease; Raphe Nuclei; Rats; Serotonin; Tyrosine 3-Monooxygenase | 1980 |
Effects of 3,4-dihydroxyphenylpyruvic acid and L-glutamic acid on some pharmacokinetic parameters of L-dopa in the rat.
Topics: Animals; Biological Availability; Brain Chemistry; Dopamine; Drug Interactions; Glutamates; Homovanillic Acid; Kinetics; Levodopa; Male; Methyldopa; Motor Activity; Phenylpyruvic Acids; Rats | 1980 |
The dopamine hypothesis: an overview of studies with schizophrenic patients.
Topics: Adenylyl Cyclases; Brain; Catechol O-Methyltransferase; Dextroamphetamine; Dopa Decarboxylase; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Receptors, Dopamine; Schizophrenia; Synapses; Tyrosine 3-Monooxygenase | 1982 |
Chronic L-DOPA-pretreatment of rats: an electrophysiological and biochemical study in the basal ganglia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Basal Ganglia; Benserazide; Corpus Striatum; Dextroamphetamine; Dopamine; Evoked Potentials; Homovanillic Acid; Levodopa; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1982 |
Possible anomalous behaviour of apomorphine in relation to other dopamine receptor agonists.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Female; Homovanillic Acid; Levodopa; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes | 1983 |
Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Alkaloids; Animals; Antipsychotic Agents; Benzylisoquinolines; Corpus Striatum; Homovanillic Acid; Injections, Intraventricular; Isoquinolines; Levodopa; Male; Mice; Phenylacetates | 1983 |
The effect of acute ethanol on dopamine metabolism and other neurotransmitters in the hypothalamus and the corpus striatum of mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; gamma-Aminobutyric Acid; Homovanillic Acid; Hypothalamus; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Norepinephrine | 1984 |
Elevated homovanillic acid in cerebrospinal fluid of children with infantile spasms.
Topics: Adrenocorticotropic Hormone; Age Factors; Child, Preschool; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Phenylacetates; Spasms, Infantile | 1980 |
Seven cases of Huntington's disease in childhood and levodopa induced improvement in the hypokinetic--rigid form.
Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Infant; Levodopa; Male; Muscle Rigidity | 1980 |
[Catecholamine and indoleamine metabolism in groups of patients with paranoid and simple forms of schizophrenia].
Topics: Adult; Biogenic Amines; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Norepinephrine; Schizophrenia; Schizophrenia, Paranoid; Serotonin | 1981 |
Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type.
Topics: Aged; Alzheimer Disease; Butyrophenones; Dementia; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Phenothiazines; Phenylacetates | 1981 |
Urinary noradrenaline and serotonin metabolites in drug-free Parkinson patients and the effect of L-dopa treatment.
Topics: Aged; Cyclic AMP; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Parkinson Disease; Serotonin | 1982 |
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Macaca mulatta; Male; Neurons; Parkinson Disease; Posture; Pyridines; Substantia Nigra | 1983 |
[Interactions of cerebral serotonin and catecholamines].
Topics: 5,7-Dihydroxytryptamine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Catecholamines; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Nerve Endings; Neurons; Norepinephrine; Rats; Serotonin; Tryptophan | 1983 |
[Malignant phenylketonuria caused by biopterin synthetase deficiency. Study of neuromediator catabolites in the cerebrospinal fluid during treatment].
Topics: Alcohol Oxidoreductases; Biopterins; Carbidopa; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Male; Neurotransmitter Agents; Phenylketonurias; Serotonin | 1984 |
Effects of drug-induced changes in brain monoamines on aggression and motor behavior in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Biogenic Amines; Brain Chemistry; Diet; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; Motor Activity; Tyrosine | 1984 |
Treatment of non-fluctuating progressive dystonia: a neuropharmacological approach.
Topics: Adolescent; Basal Ganglia; Child; Chromatography, High Pressure Liquid; Dystonia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Phenylacetates; Synaptic Transmission; Syndrome | 1984 |
Urinary homovanillic acid and c-AMP in drug-free Parkinson patients: effect of L-dopa treatment.
Topics: Aged; Carbidopa; Cyclic AMP; Drug Combinations; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates | 1981 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Callitrichinae; Caudate Nucleus; Dopamine; Female; Homovanillic Acid; Levodopa; Parkinson Disease, Secondary; Putamen; Pyridines | 1984 |
Evidence for altered catecholamine metabolism in polycystic ovary syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Carbidopa; Catecholamines; Drug Therapy, Combination; Female; Follicle Stimulating Hormone; Homovanillic Acid; Humans; Levodopa; Luteinizing Hormone; Methoxyhydroxyphenylglycol; Pituitary Hormone-Releasing Hormones; Polycystic Ovary Syndrome | 1984 |
Behavioural and biochemical alterations in the function of dopamine receptors following repeated administration of L-DOPA to rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Body Weight; Brain Chemistry; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior | 1984 |
Does acute L-DOPA increase active release of dopamine from dopaminergic neurons?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Nerve Endings; Rats; Rats, Inbred Strains | 1983 |
[3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy.
Topics: Aged; Brain; Butyrophenones; Caudate Nucleus; Dopamine; Homovanillic Acid; Humans; Levodopa; Nucleus Accumbens; Paralysis; Parkinson Disease; Phenylacetates; Putamen; Receptors, Dopamine; Spiperone; Substantia Nigra | 1984 |
[Madopar in the treatment of paralysis agitans: II. TRH activation test, EMG examination and HVA level in cerebrospinal fluid before and after treatment].
Topics: Aged; Benserazide; Drug Combinations; Electromyography; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Thyrotropin; Thyrotropin-Releasing Hormone | 1980 |
Homovanillic acid in the cerebrospinal fluid of Parkinsonian patients.
Topics: Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid | 1983 |
Rapid liquid-chromatographic measurement of 3-methoxy-4-hydroxyphenylglycol and other monoamine metabolites in human cerebrospinal fluid.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Aged; Carbidopa; Chromatography, High Pressure Liquid; Glycols; Homovanillic Acid; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Vanilmandelic Acid | 1980 |
3-O-methyldopa blocks dopa metabolism in rat corpus striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Levodopa; Male; Methyltyrosines; Parkinson Disease; Rats; Rats, Inbred Strains; Tyrosine | 1982 |
[Effect of levodopa on brain levels of noradrenaline, dopamine and homovanillic acid in experimental portosystemic encephalopathy].
Topics: Animals; Brain Chemistry; Dopamine; Hepatic Encephalopathy; Homovanillic Acid; Levodopa; Male; Norepinephrine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains | 1982 |
Normal plasma dopamine-beta-hydroxylase in non-treated and treated Parkinson patients.
Topics: Aged; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1981 |
Interference of levodopa and its metabolites with colorimetry of uric acid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Colorimetry; Dopamine; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Uric Acid | 1981 |
Striatal dopamine turnover and L-dopa treatment after short-term exposure of rats to manganese.
Topics: Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Manganese; Manganese Poisoning; Rats | 1981 |
A microdialysis study on striatal dopamine, 5-HT and metabolites in conscious rats after various treatments: evidence for extravesicular release of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Kainic Acid; Levodopa; Male; Microdialysis; Neurons; Putamen; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin; Tyramine | 1993 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Prefrontal Cortex; Probenecid; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Animals; Biogenic Monoamines; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Neostriatum; Nitriles; Pyridones; Rats; Rats, Wistar; Stereotaxic Techniques; Tryptophan; Tyrosine | 1994 |
Dopamine and serotonin turnover rate in the retina of rabbit, rat, goldfish, and Eugerres plumieri: light effects in goldfish and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Carbidopa; Dopamine; Fenclonine; Goldfish; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Light; Male; Methyltyrosines; Pargyline; Perciformes; Rabbits; Rats; Rats, Sprague-Dawley; Retina; Serotonin; Species Specificity | 1994 |
A family with hereditary juvenile dystonia-parkinsonism.
Topics: Adult; Aged; Antiparkinson Agents; Chromosome Aberrations; Chromosome Disorders; Dystonia; Female; Follow-Up Studies; Genes, Dominant; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Pedigree; Torticollis | 1995 |
Effects of the catechol-O-methyltransferase inhibitor tolcapone in Parkinson's disease: correlations between concentrations of dopaminergic substances in the plasma and cerebrospinal fluid and clinical improvement.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Dopamine; Homovanillic Acid; Humans; Levodopa; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine | 1995 |
Markers of dopamine depletion and compensatory response in striatum and cerebrospinal fluid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Parkinson Disease; Rabbits; Reserpine | 1995 |
Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Indans; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra | 1995 |
Effects of palmatine on motor activity and the concentration of central monoamines and its metabolites in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Benserazide; Berberine Alkaloids; Brain; Brain Stem; Cerebral Cortex; Dopamine; Drug Interactions; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methyltyrosines; Motor Activity; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin | 1993 |
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Mice; Mice, Inbred BALB C; Seizures; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Effect of repeated electroconvulsive shock on striatal L-dopa and dopamine metabolism: an in vivo study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1993 |
Simultaneous determination of in vivo hydroxylation of tyrosine and tryptophan in rat striatum by microdialysis-HPLC: relationship between dopamine and serotonin biosynthesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1993 |
Pharmacokinetic and pharmacodynamic studies of L-dopa in rats. II. Effect of L-dopa on dopamine and dopamine metabolite concentration in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Levodopa; Male; Models, Biological; Neostriatum; Rats; Rats, Wistar | 1994 |
Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Homovanillic Acid; Levodopa; Male; Methylation; Microdialysis; Neostriatum; Nitrophenols; Rats; Tolcapone | 1995 |
Hereditary parkinsonism with multiple system degeneration: beneficial effect of anticholinergics, but not of levodopa.
Topics: Adult; Amantadine; Basal Ganglia; Carbidopa; Cerebellar Ataxia; Cholinergic Antagonists; Consanguinity; Drug Resistance; Female; Genes, Recessive; Globus Pallidus; Homovanillic Acid; Humans; Levodopa; Magnetic Resonance Imaging; Male; Parkinson Disease; Pedigree; Trihexyphenidyl | 1994 |
'Priming' enhances the relationship of striatal L-dopa concentration to behavior.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dopamine; Homovanillic Acid; Levodopa; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 1994 |
Early L-dopa treatment initially retards but later enhances dopamine receptor supersensitivity following unilateral dopamine denervation.
Topics: Animals; Behavior, Animal; Denervation; Functional Laterality; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Rotation; Time Factors | 1994 |
Dopa-responsive dystonia simulating cerebral palsy.
Topics: Adolescent; Adult; Biopterins; Carbidopa; Cerebral Palsy; Child; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Dystonia; Female; Follow-Up Studies; Homovanillic Acid; Humans; Levodopa; Male; Neopterin; Neurologic Examination; Parkinson Disease, Secondary | 1994 |
Modulation of [3H]mazindol binding sites in rat striatum by dopaminergic agents.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Binding Sites; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Mazindol; Methyltyrosines; Neostriatum; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Wistar; Receptors, Presynaptic; Tyrosine 3-Monooxygenase | 1993 |
Dopa-responsive dystonia: pathological and biochemical observations in a case.
Topics: Adult; Brain; Child; Dopamine; Dystonia; Female; Homovanillic Acid; Humans; Levodopa; Radioligand Assay; Tyrosine 3-Monooxygenase | 1994 |
Estradiol increases tyrosine hydroxylase activity of the A15 nucleus dopaminergic neurons during long days in the ewe.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dialysis; Dopamine; Estradiol; Female; Homovanillic Acid; Hypothalamus; Levodopa; Luteinizing Hormone; Neurons; Nomifensine; Norepinephrine; Ovariectomy; Oxidopamine; Photoperiod; Sheep; Tyrosine 3-Monooxygenase | 1994 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Nomifensine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Tetrodotoxin | 1994 |
Different effects of harmine on plasma concentrations of L-dopa and on cerebral dopamine metabolism in rabbits and rats.
Topics: Animals; Brain Chemistry; Corpus Striatum; Dopamine; Harmine; Homovanillic Acid; Injections, Intravenous; Levodopa; Male; Rabbits; Rats; Rats, Wistar | 1994 |
L-dopa increases nigral production of hydroxyl radicals in vivo: potential L-dopa toxicity?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Hydroxyl Radical; Levodopa; Microdialysis; Mitochondria; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Selegiline; Stereotaxic Techniques; Substantia Nigra | 1994 |
Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with or without pretreatment with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Homovanillic Acid; Levodopa; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurons; Oxidopamine; Thiobarbituric Acid Reactive Substances | 1994 |
Biochemical and fluorodopa positron emission tomographic findings in an asymptomatic carrier of the gene for dopa-responsive dystonia.
Topics: Adolescent; Adult; Aged; Biopterins; Dystonia; Female; Fluorine Radioisotopes; Heterozygote; Homovanillic Acid; Humans; Levodopa; Male; Neopterin; Pedigree; Tomography, Emission-Computed | 1994 |
Chronic administration does not alter the accumulation of L-dopa into muscle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Carbidopa; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Long-Term Care; Male; Metabolic Clearance Rate; Muscles; Rats; Rats, Wistar | 1994 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, Dopamine D2; Sensitivity and Specificity; Substantia Nigra; Time Factors | 1993 |
Dopaminergic abnormalities in hypertension associated with moderate renal insufficiency.
Topics: 3,4-Dihydroxyphenylacetic Acid; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Diastole; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hypertension; Kidney Failure, Chronic; Levodopa; Male; Middle Aged; Reference Values; Sodium | 1994 |
Assessment of the dopaminergic lesion in Parkinson's disease by CSF markers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Brain; Dopamine; Homovanillic Acid; Humans; Levodopa; Neurons; Parkinson Disease | 1993 |
Potent COMT inhibition by Ro 40-7592 in the periphery and in the brain. Preclinical and clinical findings.
Topics: Animals; Benserazide; Benzophenones; Brain; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Homovanillic Acid; Humans; Levodopa; Male; Nitrophenols; Peripheral Nerves; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tolcapone | 1993 |
Plasma levels of levodopa and its main metabolites in parkinsonian patients after conventional and controlled-release levodopa-carbidopa associations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Blood-Brain Barrier; Carbidopa; Delayed-Action Preparations; Dopamine; Dose-Response Relationship, Drug; Drug Combinations; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Tyrosine | 1993 |
The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Electrocardiography; Half-Life; Homovanillic Acid; Humans; Levodopa; Male; Nitriles; Reference Values; Tyrosine | 1993 |
A clinical and pharmacokinetic case study of an interaction of levodopa and antituberculous therapy in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antitubercular Agents; Dopa Decarboxylase; Homovanillic Acid; Humans; Isoniazid; Levodopa; Male; Middle Aged; Parkinson Disease; Rifampin; Tuberculosis, Pulmonary | 1995 |
L-DOPA and psychosis: evidence for L-DOPA-induced increases in prefrontal cortex dopamine and in serum corticosterone.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Corticosterone; Dopamine; Homovanillic Acid; Levodopa; Male; Prefrontal Cortex; Psychoses, Substance-Induced; Rats; Rats, Sprague-Dawley; Regression Analysis; Risk Factors | 1995 |
Assessment of renal dopaminergic system activity during cyclosporine A administration in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Catechol O-Methyltransferase; Creatinine; Cyclosporine; Dopamine; Homovanillic Acid; In Vitro Techniques; Injections, Subcutaneous; Kidney Cortex; Kidney Tubules; Levodopa; Male; Monoamine Oxidase; Potassium; Rats; Rats, Wistar; Sodium; Urea | 1995 |
Effects of Hemerocallis flava on motor activity and the concentration of central monoamines and its metabolites in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Amines; Analysis of Variance; Animals; Benserazide; Brain Stem; Cerebral Cortex; Dopamine; Dopamine Agents; Enzyme Inhibitors; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Mandelic Acids; Methyltyrosines; Motor Activity; Norepinephrine; Plant Extracts; Plants, Medicinal; Rats; Serotonin; Serotonin Agents | 1996 |
Slow increase of homovanillic acid in cerebrospinal fluid after levodopa administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Carbidopa; Drug Administration Schedule; Drug Combinations; Female; Homovanillic Acid; Humans; Hydrocephalus; Levodopa; Male; Middle Aged | 1996 |
In vivo microdialysis to determine the relative pharmacokinetics of drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benserazide; Brain Chemistry; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Interactions; Electrochemistry; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Microdialysis; Neostriatum; Rats; Rats, Wistar | 1996 |
Circadian phase dependent pharmacokinetics of L-dopa, its main metabolites (3-OMD, HVA, DOPAC) and carbidopa in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Area Under Curve; Carbidopa; Circadian Rhythm; Half-Life; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Wistar | 1996 |
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine | 1996 |
Peripheral and central inhibitors of catechol-O-methyl transferase: effects on liver and brain COMT activity and L-DOPA metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Homovanillic Acid; Levodopa; Liver; Male; Nitriles; Rats; Rats, Sprague-Dawley | 1997 |
Plasma HVA and MHPG in psychiatric patients with renal failure and levodopa-treated Parkinson's disease.
Topics: Adult; Aged; Depressive Disorder; Female; Homovanillic Acid; Humans; Kidney Failure, Chronic; Levodopa; Male; Mental Disorders; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease; Psychotic Disorders; Renal Dialysis | 1996 |
Microdialysis-HPLC for plasma levodopa and metabolites monitoring in parkinsonian patients.
Topics: Aged; Carbidopa; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Kinetics; Levodopa; Microdialysis; Middle Aged; Parkinson Disease | 1997 |
Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa.
Topics: Adult; Aged; Homovanillic Acid; Humans; Levodopa; Middle Aged; Parkinson Disease | 1997 |
Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a second family.
Topics: 5-Hydroxytryptophan; Amino Acids, Cyclic; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; Child, Preschool; Consanguinity; Developmental Disabilities; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Iran; Levodopa; Longitudinal Studies; Male; Methoxyhydroxyphenylglycol; Muscle Hypotonia; Pyridoxine | 1997 |
Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Catecholamines; Cell Transplantation; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Female; Fibroblasts; Genetic Therapy; GTP Cyclohydrolase; Homovanillic Acid; Levodopa; Microdialysis; Parkinson Disease; Rats; Rats, Inbred F344; Recombinant Proteins; Transfection; Tyrosine 3-Monooxygenase | 1997 |
Decreased beta-phenylethylamine in CSF in Parkinson's disease.
Topics: Aged; Chromatography, Gas; Female; Homovanillic Acid; Humans; Levodopa; Male; Mass Spectrometry; Middle Aged; Parkinson Disease; Peripheral Nervous System Diseases; Phenethylamines; Psychotropic Drugs; Severity of Illness Index | 1997 |
Assessment of renal dopaminergic system activity during the recovery of renal function in human kidney transplant recipients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kidney; Kidney Transplantation; Levodopa; Male; Middle Aged; Postoperative Period | 1997 |
[Effect of subchronic administration of tolcapone on release of striatum dopamine and its metabolites induced by L-DOPA and carbidopa].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dopamine; Dopamine Agents; Drug Synergism; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Nitrophenols; Rats; Rats, Wistar; Tolcapone | 1998 |
Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Homovanillic Acid; Indans; Isoenzymes; Levodopa; Macaca mulatta; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 1998 |
L-DOPA exacerbates amphetamine-induced dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Synergism; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; Organ Specificity; Serotonin | 1998 |
Dopamine metabolism in the striatum of hemiparkinsonian model rats with dopaminergic grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetal Tissue Transplantation; Functional Laterality; Haloperidol; Homovanillic Acid; Kinetics; Levodopa; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Methamphetamine; Microdialysis; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Tritium; Tyrosine 3-Monooxygenase | 1998 |
Salsolinol, catecholamine metabolites, and visual hallucinations in L-dopa treated patients with Parkinson's disease.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Biomarkers; Catecholamines; Female; Hallucinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Isoquinolines; Levodopa; Male; Parkinson Disease; Reference Values; Regression Analysis; Tyrosine | 1996 |
Elevated 5-S-cysteinyldopamine/homovanillic acid ratio and reduced homovanillic acid in cerebrospinal fluid: possible markers for and potential insights into the pathoetiology of Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Biomarkers; Chromatography, High Pressure Liquid; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Parkinson Disease; Reference Values | 1996 |
In vivo comparison of the effects of inhibition of MAO-A versus MAO-B on striatal L-DOPA and dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline | 1995 |
Hereditary form of parkinsonism--dementia.
Topics: Adult; Antiparkinson Agents; Choline O-Acetyltransferase; Dementia; Dopamine; Family Health; Female; Genes, Dominant; Hippocampus; Homovanillic Acid; Humans; Levodopa; Lewy Bodies; Locus Coeruleus; Male; Middle Aged; Neostriatum; Nerve Degeneration; Neuropsychological Tests; Parkinson Disease; Pedigree; Substantia Innominata; Substantia Nigra; Temporal Lobe; Tomography, Emission-Computed | 1998 |
Reduced urinary excretion of dopamine and metabolites in chronic renal parenchymal disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Biopsy; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Chronic Disease; Creatinine; Dopamine; Female; Follow-Up Studies; Glomerulonephritis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kidney Tubules; Levodopa; Male; Middle Aged; Monoamine Oxidase; Phosphates; Potassium; Sodium | 1998 |
Liquid chromatographic analysis of brain homogenates and microdialysates for the quantification of L-[beta-11C]DOPA and its metabolites for the validation of positron emission tomography studies.
Topics: Animals; Brain Chemistry; Carbon Radioisotopes; Chromatography, Liquid; Dopamine; Homovanillic Acid; Isotope Labeling; Levodopa; Male; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed | 1995 |
Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Biotransformation; Corpus Striatum; Decarboxylation; Dopamine; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Muscarinic Antagonists; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Trihexyphenidyl | 1998 |
Renal dopaminergic system in nephrotic syndrome and after remission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Child; Dopamine; Drug Therapy, Combination; Edema; Female; Follow-Up Studies; Glucocorticoids; Homovanillic Acid; Humans; Immunosuppressive Agents; Levodopa; Male; Nephrosis, Lipoid; Norepinephrine; Proteinuria; Remission Induction; Sodium | 1998 |
Catecholaminergic mechanisms-mediated hypothermia induced by magnolol in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Body Temperature; Catecholamines; Colon; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Homovanillic Acid; Hypothalamus; Hypothermia, Induced; Injections, Intraperitoneal; Injections, Intraventricular; Levodopa; Lignans; Male; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley | 1998 |
Effect of Cassava on motor co-ordination and neurotransmitter level in the albino rat.
Topics: Analysis of Variance; Animals; Brain; Dopamine; Homovanillic Acid; Indoles; Levodopa; Male; Manihot; Motor Skills; Neurotransmitter Agents; Protein-Energy Malnutrition; Rats; Rats, Wistar; Serotonin; Solanum tuberosum | 1999 |
Time-dependent effects of levodopa on regional brain dopamine metabolism and lipid peroxidation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebellum; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Lipid Peroxidation; Male; Mesencephalon; Oxidative Stress; Parkinson Disease, Secondary; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Pergolide potentiates L-DOPA-induced dopamine release in rat striatum after lesioning with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Synergism; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Pergolide; Rats; Rats, Wistar | 1999 |
Neurotoxic effects of amphetamine plus L-DOPA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Frontal Lobe; Homovanillic Acid; Hypothalamus; Levodopa; Male; Mice; Neurons; Neurotoxins; Organ Specificity; Serotonin; Time Factors | 1999 |
Microdialysis studies on the action of tolcapone on pharmacologically-elevated extracellular dopamine levels in conscious rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Extracellular Space; Haloperidol; Homovanillic Acid; Levodopa; Male; Microdialysis; Nitrophenols; Piperazines; Rats; Rats, Wistar; Time Factors; Tolcapone; Visual Cortex | 1999 |
Reserpine pretreatment prevents increases in extracellular striatal dopamine following L-DOPA administration in rats with nigrostriatal denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Denervation; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Reserpine; Substantia Nigra | 2000 |
Modulation of dihydroxyphenylacetaldehyde extracellular levels in vivo in the rat striatum after different kinds of pharmacological treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Homovanillic Acid; Levodopa; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley | 2000 |
The effects of melatonin and L-DOPA on the diurnal rhythms of free amino acids content in the rat retina.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Lighting; Male; Melatonin; Rats; Rats, Wistar; Retina | 2000 |
Serotonergic decompensation in the akinetic expression of Parkinson's disease.
Topics: Brain; Chromatography, High Pressure Liquid; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Levodopa; Methoxyhydroxyphenylglycol; Norepinephrine; Parkinson Disease; Serotonin; Synaptic Transmission | 2000 |
Evaluation of L-DOPA biotransformation during repeated L-DOPA infusion into the striatum in freely-moving young and old rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Locomotion; Male; Microdialysis; Rats; Rats, Wistar | 2000 |
L-DOPA and high oxygen influence release of catecholamines from the cat carotid body.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotid Body; Catecholamines; Cats; Chemoreceptor Cells; Dopamine; Female; Homovanillic Acid; In Vitro Techniques; Levodopa; Male; Norepinephrine; Oxygen | 2000 |
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid | 2000 |
The influence of L-dopa on methylation capacity in aromatic L-amino acid decarboxylase deficiency: biochemical findings in two patients.
Topics: Amino Acid Metabolism, Inborn Errors; Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypokinesia; Levodopa; Methoxyhydroxyphenylglycol; Methylation; Muscle Hypotonia; Tetrahydrofolates; Tyrosine | 2000 |
Pathobiochemical implications of hyperdopaminuria in patients with aromatic L-amino acid decarboxylase deficiency.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aromatic-L-Amino-Acid Decarboxylases; Dopamine; Homovanillic Acid; Humans; Levodopa | 2000 |
Variable absorption of carbidopa affects both peripheral and central levodopa metabolism.
Topics: Absorption; Adult; Aged; Antiparkinson Agents; Brain; Carbidopa; Child; Homovanillic Acid; Humans; Levodopa; Middle Aged | 2000 |
Bromocriptine markedly suppresses levodopa-induced abnormal increase of dopamine turnover in the parkinsonian striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bromocriptine; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2000 |
N-methyl(R)salsolinol and a neutral N-methyltransferase as pathogenic factors in Parkinson's disease.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Brain; Female; Homovanillic Acid; Humans; Levodopa; Lymphocytes; Male; Methyltransferases; Middle Aged; Parkinson Disease; Salsoline Alkaloids; Statistics, Nonparametric; Tetrahydroisoquinolines | 2000 |
Effect of 6-fluoro-m-tyrosine on dopamine release and metabolism in rat striatum using in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Fluorine Radioisotopes; Homovanillic Acid; Levodopa; Male; Microdialysis; Neostriatum; Neurons; Rats; Rats, Sprague-Dawley; Tyrosine | 2000 |
Concerted action of dopamine on renal and intestinal Na(+)-K(+)-ATPase in the rat remnant kidney.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaline Phosphatase; Animals; Aromatic-L-Amino-Acid Decarboxylases; Catechol O-Methyltransferase; Dopamine; Electrolytes; gamma-Glutamyltransferase; Homovanillic Acid; Intestines; Jejunum; Kidney; Levodopa; Male; Monoamine Oxidase; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Water-Electrolyte Imbalance | 2000 |
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine | 2001 |
Changes in endogenous monoamines in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Catechol O-Methyltransferase; Cerebral Cortex; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Serotonin | 2001 |
BIA 3-202, a novel catechol-O-methyltransferase inhibitor, enhances the availability of L-DOPA to the brain and reduces its O-methylation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetophenones; Animals; Biological Availability; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Methylation; Rats; Rats, Wistar; Time Factors; Tyrosine | 2001 |
Heart failure, aging, and renal synthesis of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Aging; Aldosterone; Cardiac Output, Low; Case-Control Studies; Creatinine; Diet, Sodium-Restricted; Dopamine; Echocardiography; Female; Homovanillic Acid; Humans; Kidney; Levodopa; Male; Middle Aged; Norepinephrine; Statistics as Topic; Urine | 2001 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbidopa; Carrier Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Succinate Dehydrogenase; Sulpiride; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypokinesia; Immunohistochemistry; Isoquinolines; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Serotonin; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 2001 |
COMT-inhibition increases serum levels of dihydroxyphenylacetic acid (DOPAC) in patients with advanced Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine | 2002 |
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Carbidopa; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Female; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyldopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Norepinephrine | 2002 |
PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2002 |
Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Forelimb; Homovanillic Acid; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Neuropeptides; Parkinsonian Disorders; Postural Balance; Recovery of Function; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins; Walking | 2002 |
An antihypokinesic action of alpha2-adrenoceptors upon MPTP-induced behaviour deficits in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clonidine; Dopamine; Dopamine Agonists; Drug Interactions; Drug Therapy, Combination; Guanfacine; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Parkinsonian Disorders; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Yohimbine | 2003 |
[The effect of shourong compound formula on levels of dopamine and its metabolites in brain of Parkinson's disease mice induced by reserpine].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Dopamine; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Homovanillic Acid; Levodopa; Male; Mice; Parkinson Disease, Secondary; Plant Extracts; Plants, Medicinal; Reserpine | 2002 |
An investigation of dopaminergic metabolites in the striatum and in the substantia nigra in vivo utilising radiolabelled L-DOPA and high performance liquid chromatography: a new approach in the search for transmitter metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Enzyme Inhibitors; Homovanillic Acid; Isothiocyanates; Levodopa; Male; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tritium | 2003 |
Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Ditiocarb; Dopamine; Drug Synergism; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Parkinsonian Disorders; Reaction Time; Recovery of Function; Selegiline; Serotonin | 2003 |
[Pseudopheochromocytoma in Parkinson disease and depression].
Topics: Adrenal Gland Neoplasms; Antidepressive Agents; Antiparkinson Agents; Catecholamines; Depressive Disorder; Diagnosis, Differential; Dopamine Agonists; Drug Therapy, Combination; Female; Flushing; Homovanillic Acid; Humans; Hypertension; Indoles; Levodopa; Middle Aged; Parkinson Disease; Pheochromocytoma; Vanilmandelic Acid | 2003 |
Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Dopamine; Homovanillic Acid; Immunohistochemistry; Levodopa; Male; Mice; MPTP Poisoning; Neuropeptide Y; Neuroprotective Agents; Selegiline; Serotonin | 2003 |
Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl)caffeine on L-DOPA biotransformation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Benserazide; Brain Chemistry; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Reserpine | 2004 |
Calcium ions: its role in cyanide neurotoxicity.
Topics: Animals; Calcium; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Corpus Striatum; Diltiazem; Dopamine; Drug Antagonism; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Ions; Lethal Dose 50; Levodopa; Male; Poisons; Rats; Rats, Wistar; Serotonin; Sodium Cyanide | 2004 |
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzylamines; Brain Chemistry; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Statistics, Nonparametric; Tyrosine | 2004 |
Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain; Brocresine; Chromatography, High Pressure Liquid; Deferoxamine; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Functional Laterality; Homovanillic Acid; Iron; Iron Chelating Agents; Levodopa; Male; Motor Activity; Neurodegenerative Diseases; Neurotransmitter Agents; Oxidopamine; Parkinson Disease; Piperazines; Quinolines; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Novel dopamine releasing response of an anti-convulsant agent with possible anti-Parkinson's activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Isoxazoles; Levodopa; Microdialysis; Oxidopamine; Parkinson Disease; Rats; Zonisamide | 2004 |
Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Area Under Curve; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Malonates; Methyltyrosines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reserpine; Serotonin; Substantia Nigra; Time Factors; Triazines; Triazoles; Xanthines | 2004 |
AMPA receptor blockade potentiates the stimulatory effect of L-DOPA on dopamine release in dopamine-deficient corticostriatal slice preparation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Dopamine Agents; Electric Stimulation; Homovanillic Acid; In Vitro Techniques; Levodopa; Neostriatum; Oxidopamine; Rats; Receptors, AMPA; Sympatholytics | 2004 |
Dopamine agonist cabergoline inhibits levodopa-induced caspase activation in 6-OHDA-lesioned mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cabergoline; Carbidopa; Caspases; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Drug Combinations; Drug Interactions; Enzyme Activation; Ergolines; Glutathione; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2005 |
Levodopa-responsive infantile parkinsonism due to a novel mutation in the tyrosine hydroxylase gene and exacerbation by viral infections.
Topics: Animals; Antiparkinson Agents; Central Nervous System Viral Diseases; Child, Preschool; DNA Mutational Analysis; Female; Histidine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Mice; Mutation; Parkinsonian Disorders; Rats; Treatment Outcome; Tyrosine; Tyrosine 3-Monooxygenase | 2005 |
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Benzoquinones; Benzothiazoles; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electron Spin Resonance Spectroscopy; Functional Laterality; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Oxidopamine; Parkinson Disease; Pramipexole; Thiazoles; Time Factors | 2005 |
Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dyskinesias; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Membrane Potentials; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 2006 |
Reuptake of L-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Fluoxetine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2006 |
Effects of subchronic treatment with selegiline on L-DOPA-induced increase in extracellular dopamine level in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Space; Homovanillic Acid; Injections, Intraperitoneal; Levodopa; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Time Factors | 2006 |
Evaluation of an osmotic pump for microdialysis sampling in an awake and untethered rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain Chemistry; Dopamine; Extracellular Fluid; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusion Pumps; Levodopa; Male; Microdialysis; Neurochemistry; Neurotransmitter Agents; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Serotonin; Up-Regulation; Wakefulness | 2007 |
Aromatic L-amino acid decarboxylase enzyme activity in deficient patients and heterozygotes.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic-L-Amino-Acid Decarboxylases; Child; Child, Preschool; Heterozygote; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa | 2007 |
Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agents; Drug Interactions; Functional Laterality; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2007 |
Long-term survival of encapsulated GDNF secreting cells implanted within the striatum of parkinsonized rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cell Line; Cell Survival; Corpus Striatum; Dopamine; Drug Compounding; Drug Delivery Systems; Fibroblasts; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Levodopa; Male; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2007 |
A case of 6-pyruvoyl-tetrahydropterin synthase deficiency demonstrates a more significant correlation of L-Dopa dosage with serum prolactin levels than CSF homovanillic acid levels.
Topics: 5-Hydroxytryptophan; Biomarkers; Biopterins; Brain Diseases, Metabolic; Child, Preschool; Dopamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hypothalamo-Hypophyseal System; Levodopa; Phosphorus-Oxygen Lyases; Predictive Value of Tests; Prolactin | 2008 |
Modulation of the motor response to dopaminergic drugs in a parkinsonian model of combined dopaminergic and noradrenergic degeneration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Benzylamines; Brain; Caffeine; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2007 |
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Benserazide; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar | 2008 |
Mitochondrial diseases mimicking neurotransmitter defects.
Topics: Alanine; Brain; Child, Preschool; Consanguinity; Diagnosis, Differential; Dopamine Agents; Dystonia; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Lactic Acid; Levodopa; Male; Mitochondrial Diseases; Neurotransmitter Agents; Pterins; Radiography; Treatment Outcome | 2008 |
Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2.
Topics: Amphetamine; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Corpus Striatum; Dopamine; Dyskinesias; Glutamine; Homovanillic Acid; Levodopa; Male; Morpholines; Naphthalenes; Oxidopamine; Rats; Rats, Wistar | 2009 |
Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Area Under Curve; Benserazide; Catalepsy; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Time Factors; Triazines; Triazoles; Xanthines | 2009 |
Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Body Weight; Cognition; Conditioning, Operant; Corpus Striatum; Discrimination Learning; Dopamine; Dopamine Agents; Exploratory Behavior; Feeding Behavior; Female; Gene Expression Regulation; Gene Transfer Techniques; Homovanillic Acid; Levodopa; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuropsychological Tests; Recognition, Psychology; Signal Transduction; Tyrosine 3-Monooxygenase | 2010 |
Biochemical alterations of dopamine receptor responses following chronic L-dopa therapy.
Topics: Adenylyl Cyclases; Animals; Carbidopa; Corpus Striatum; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spiperone | 1980 |
Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Enzyme Inhibitors; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Microdialysis; Monoamine Oxidase Inhibitors; Neostriatum; Pargyline; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2011 |
Distinct effects of intranigral L-DOPA infusion in the MPTP rat model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Cell Count; Disease Models, Animal; Dopamine; Drug Interactions; Gene Expression Regulation; Homovanillic Acid; Levodopa; Male; Movement; Neurons; Neurotoxins; Parkinsonian Disorders; Rats; Rats, Wistar; Reaction Time; Substantia Nigra; Tyrosine 3-Monooxygenase | 2009 |
Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis.
Topics: Age of Onset; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Catecholamines; Child, Preschool; Disease Progression; Dopamine Agents; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypokinesia; Infant; Levodopa; Muscle Rigidity; Mutation, Missense; Phenotype; Promoter Regions, Genetic; Severity of Illness Index; Tyrosine 3-Monooxygenase | 2010 |
Salicylic acid protects against chronic L-DOPA-induced 6-OHDA generation in experimental model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Salicylates | 2010 |
L-DOPA reverses motor deficits associated with normal aging in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Psychomotor Performance | 2011 |
Deletion in the tyrosine hydroxylase gene in a patient with a mild phenotype.
Topics: Antiparkinson Agents; Carbidopa; DNA Mutational Analysis; Drug Combinations; Female; Homovanillic Acid; Humans; Infant; Levodopa; Movement Disorders; Phenotype; Sequence Deletion; Tyrosine 3-Monooxygenase; Video Recording | 2011 |
Aberrant striatal dopamine transmitter dynamics in brain-derived neurotrophic factor-deficient mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain-Derived Neurotrophic Factor; Chromatography, Liquid; Corpus Striatum; Dopamine; Electric Stimulation; Electrochemical Techniques; Extracellular Fluid; Homeostasis; Homovanillic Acid; Levodopa; Linear Models; Mice; Mice, Knockout; Microdialysis; Motor Activity; Potassium Chloride; Time Factors | 2012 |
Chronic 5-HT transporter blockade reduces DA signaling to elicit basal ganglia dysfunction.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Basal Ganglia; Cell Count; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Fluoxetine; Homovanillic Acid; Levodopa; Male; Mice; Mice, Transgenic; Movement Disorders; Psychomotor Performance; Random Allocation; Rotarod Performance Test; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Substantia Nigra; Ventral Tegmental Area | 2011 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Triazines; Triazoles; Vesicular Monoamine Transport Proteins | 2012 |
Toxicity and metabolism of layered double hydroxide intercalated with levodopa in a Parkinson's disease model.
Topics: Aluminum; Animals; Cell Line; Cell Survival; Homovanillic Acid; Hydroxides; Levodopa; Nanocomposites; Nanoconjugates; Nanoparticles; Parkinsonian Disorders; PC12 Cells; Rats; Zinc | 2014 |
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetus; Herbicides; Homovanillic Acid; Levodopa; Maternal-Fetal Exchange; Nuclear Receptor Subfamily 4, Group A, Member 2; Pregnancy; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2014 |
Coadministration of β-asarone and levodopa increases dopamine in rat brain by accelerating transformation of levodopa: a different mechanism from Madopar.
Topics: 3,4-Dihydroxyphenylacetic Acid; Allylbenzene Derivatives; Animals; Anisoles; Benserazide; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Drug Combinations; Drug Interactions; Homovanillic Acid; Levodopa; Male; Monoamine Oxidase; Rats; Serotonin; Tyrosine 3-Monooxygenase | 2014 |
Effect of a chronic treatment with an mGlu5 receptor antagonist on brain serotonin markers in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Levodopa; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Protein Binding; Pyridines; Serotonin | 2015 |
Contribution of dopamine to mitochondrial complex I inhibition and dopaminergic deficits caused by methylenedioxymethamphetamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aconitate Hydratase; alpha-Methyltyrosine; Animals; Body Temperature; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Gene Expression Regulation; Hallucinogens; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Tyrosine 3-Monooxygenase | 2015 |
Subthalamic Nucleus Deep Brain Stimulation Modulate Catecholamine Levels with Significant Relations to Clinical Outcome after Surgery in Patients with Parkinson's Disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Area Under Curve; Catecholamines; Deep Brain Stimulation; Female; Homovanillic Acid; Humans; Levodopa; Linear Models; Male; Middle Aged; Parkinson Disease; Postoperative Period; Quality of Life; ROC Curve; Severity of Illness Index; Subthalamic Nucleus; Treatment Outcome | 2015 |
Homovanillic acid in CSF of mild stage Parkinson's disease patients correlates with motor impairment.
Topics: Aged; Antiparkinson Agents; Biomarkers; Disease Progression; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Motor Skills Disorders; Parkinson Disease | 2017 |
Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aging; Antiparkinson Agents; Catecholamines; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease | 2017 |
Preliminary Analysis of Parkinson-like Motor Coordination Abnormityin Brain-specific hS100B Transgenic Mice.
Topics: Animals; Brain; Disease Models, Animal; Dopamine; G-Protein-Coupled Receptor Kinase 2; Homovanillic Acid; Levodopa; Mice; Mice, Knockout; Mice, Transgenic; Parkinson Disease; Receptors, Dopamine D2; S100 Calcium Binding Protein beta Subunit; Tyrosine 3-Monooxygenase | 2017 |
Dose-Dependent Effects of Binge-Like Methamphetamine Dosing on Dopamine and Neurotrophin Levels in Rat Brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Gene Expression Regulation; Homovanillic Acid; Levodopa; Locomotion; Male; Methamphetamine; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Time Factors | 2017 |
Teaching Video NeuroImage: Improvement in Motor Development After Start of Levodopa in Tyrosine Hydroxylase Deficiency.
Topics: Developmental Disabilities; Dopamine Agents; Dystonic Disorders; Exome; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Male; Mutation; Treatment Outcome | 2021 |
Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Homovanillic Acid; Humans; Levodopa; Neurotransmitter Agents; Parkinson Disease | 2021 |