levodopa has been researched along with gamma-aminobutyric acid in 159 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (42.77) | 18.7374 |
| 1990's | 18 (11.32) | 18.2507 |
| 2000's | 39 (24.53) | 29.6817 |
| 2010's | 27 (16.98) | 24.3611 |
| 2020's | 7 (4.40) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Shute, CC | 1 |
| Lane, JD; McBride, WJ; Shea, PA; Smith, JE | 1 |
| Lloyd, KG | 1 |
| Rinne, UK | 1 |
| Costentin, J | 1 |
| Carolei, A; Del Castillo, G | 1 |
| Bartholini, G | 2 |
| Marsden, CD; Parkes, JD | 1 |
| Klawans, HL; Weiner, WJ | 1 |
| Chase, TN | 1 |
| Calne, DB; Eisler, T | 1 |
| Jezová-Repceková, D | 1 |
| Lazarova, MB; Roussinov, KS | 1 |
| Georgiev, VP; Markovska, VL; Petkova, BP | 1 |
| Fukuda, N; Miyamoto, M; Nagai, Y; Nagawa, Y; Narumi, S; Shima, T | 1 |
| Hosoki, H; Ofuji, T; Takahara, J | 1 |
| Cottrell, GA; Turner, JD | 1 |
| Calne, DB; Eng, N; Nutt, J; Plotkin, C; Williams, A; Ziegler, M | 1 |
| Agostini, L; Firenze, C; Gallai, V; Piccinin, GL; Piccirilli, M; Rossi, A | 1 |
| Di Giorgio, RM; Lanotte, M; Macaione, S; Nistico, G | 1 |
| Carchedi, F; Casacchia, M; Di Ceglie, M; Meco, G | 1 |
| Fahn, S; Hutt, CS; Snider, SR | 1 |
| Koskinen, V; Laaksonen, H; Lönnberg, P; Rinne, UK; Sonninen, V | 1 |
| Hornykiewics, O; Lloyd, KG | 1 |
| Luchins, D | 1 |
| Burke, M; Earley, B; Leonard, BE | 1 |
| Baev, KV; Rusin, KI; Safronov, BV | 1 |
| Aceves, J; Floran, B; Hernandez, S; Mariscal, S; Martinez-Fong, D; Sierra, A | 1 |
| Chase, TN; Engber, TM; Susel, Z; Walters, JR; Weick, BG | 1 |
| Biswas, S; Poddar, MK | 1 |
| Boyce, S; Clarke, CA; Crossman, AR; Robertson, RG; Sambrook, MA | 1 |
| Persson, B; Rubenson, A; Sillén, U | 2 |
| Klawans, HL | 1 |
| Hulting, AL; Meister, B | 1 |
| Bossi, L; Fournier, V; Morselli, PL; Musch, B | 1 |
| Commissiong, JW | 1 |
| Cassel, G; Persson, SA; Sellström, A | 1 |
| Bathien, N; Fournier, V; Morselli, PL; Rondot, P; Ziegler, M | 1 |
| Agid, Y; Bonnet, AM; De Smet, Y; Grove, J; Saint-Hilaire, MH; Schechter, PJ; Tell, G | 1 |
| Goldstein, M; Lloyd, KG; Willigens, MT | 1 |
| Pranzatelli, MR; Snodgrass, SR | 1 |
| Longo, VG; Massotti, M | 1 |
| Angel, A | 1 |
| Barone, G; Carotti, A; Lucciarini, L; Mugnai, A; Tomassetti, G | 1 |
| Barbeau, A | 1 |
| Bartholini, G; Lloyd, KG | 1 |
| Lloyd, KG; Worms, P | 1 |
| Enna, SJ; Lake, CR; Teychenné, PF; Ziegler, MG | 1 |
| Lazarova, M; Roussinov, K | 1 |
| Ananth, J | 1 |
| Hassler, RG | 1 |
| Bergmann, KJ; Limongi, JC; Lowe, YH; Mendoza, MR; Yahr, MD | 1 |
| Woodbury, DM | 1 |
| Hadjiconstantinou, M; Neff, NH | 1 |
| Kurako, IuL; Volianskiĭ, VE | 1 |
| Colucci d'Amato, C; Cristillo, A; Puccini, A; Vizioli, R | 1 |
| Saeed Dar, M; Wooles, WR | 1 |
| Coletti, A; Mandelli, A; Minoli, G; Tredici, G | 1 |
| Czuczwar, SJ; Kleinrok, Z; Kozicka, M | 1 |
| Cross, AJ; Dashwood, MJ; Deakin, JF; Owen, F | 1 |
| Koulu, M; Lammintausta, R | 1 |
| Gerber, JC; Grossman, MH; Hare, TA; Katz, L; Manyam, NV | 1 |
| Goetz, CG; Klawans, HL; Perlik, S | 1 |
| de Jong, PJ; Lakke, JP; Teelken, AW | 1 |
| Dahlström, S; Koulu, M; Lammintausta, R | 1 |
| Kucharski, LT; Unterwald, EM | 1 |
| Georgiev, V; Markovska, V | 1 |
| Kameyama, M; Nakamura, S | 1 |
| Manyam, BV | 1 |
| Ikeda, K; Krause, DN; Roberts, E | 1 |
| Hosogi, H; Kageyama, J; Ofuji, T; Takahara, J; Yakushiji, W; Yunoki, S | 1 |
| Nistico, G | 1 |
| Ghosh, S; Poddar, MK | 1 |
| Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J | 1 |
| Amabeoku, G; Chikuni, O | 1 |
| Ferracci, F; Fulgente, T; Ghilardi, MF; Malatesta, G; Onofrj, M | 1 |
| Kanazawa, I; Kimura, M; Murata, M | 1 |
| Matsuoka, H; Mizoguchi, K; Nishimura, Y; Obi, T; Takatsu, M | 1 |
| Iacovitti, L; Stull, ND | 1 |
| Goshima, Y; Misu, Y; Miyamae, T; Yue, JL | 1 |
| Ahier, RG; Ashworth, S; Hume, SP; Opacka-Juffry, J | 1 |
| Goshima, Y; Honjo, K; Misu, Y; Miyamae, T | 2 |
| Consolo, S; Di Chiara, G; Giorgi, S; Morelli, M; Rimoldi, M | 1 |
| Bédard, PJ; Doan, VD; Grondin, R; Hadj Tahar, A; Ladure, P | 1 |
| Ebinger, G; Izurieta-Sánchez, P; Michotte, Y; Sarre, S | 1 |
| Schmidt, WJ | 1 |
| Yazaki, I | 1 |
| Akbar, M; Ishihara, K; Misu, Y; Sasa, M | 1 |
| Clauss, W; Milde, H; Salzet, M; Weber, WM | 1 |
| Fisenko, VP | 1 |
| Brotchie, JM; Crossman, AR; Dick, JP; Fox, SH; Hill, M; Sieradzan, KA | 1 |
| Bernardi, G; Federici, M; Mercuri, NB; Natoli, S | 1 |
| Aziz, TZ; Giladi, N; Nandi, D; Stein, JF; Winter, J | 1 |
| Brotchie, J; Crossman, A; Fox, SH; Henry, B; Hill, M | 1 |
| Morikawa, H; Paladini, CA; Palmiter, RD; Robinson, S; Williams, JT | 1 |
| Sethi, KD | 1 |
| Aoyama, S; Bedard, P; Borrelli, E; Chase, TN; Hauser, RA; Ichimura, M; Ikeda, K; Ishii, A; Jenner, P; Kanda, T; Kase, H; Koga, K; Koike, N; Kurokawa, M; Kuwana, Y; Mori, A; Nakamura, J; Nonaka, H; Ochi, M; Richardson, PJ; Saki, M; Shimada, J; Shindou, T; Shiozaki, S; Suzuki, F; Takeda, M; Yanagawa, K | 1 |
| Kase, H; Ochi, M; Shiozaki, S | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Picconi, B; Rossi, S | 1 |
| Bassetti, CL; Clavadetscher, SC; Gugger, M | 1 |
| Haberal, M; Kut, A; Micozkadioglu, H; Ozdemir, FN; Saatci, U; Sezer, S | 1 |
| Connell, MA; Emborg, ME; Li, Q; Meglasson, MD; Merchant, K; Simmons, C; Stephenson, DT | 1 |
| Brotchie, JM; Crossman, AR; Di Marzo, V; Fox, SH; Hill, M; Petrosino, S; van der Stelt, M | 1 |
| Molnar, MZ; Mucsi, I; Novak, M | 1 |
| Aceves, J; Cortes, H; Erlij, D; Escartín, E; Florán, B; Florán, L; Rangel, C; Silva, I | 1 |
| Pierce, RC; Soghomonian, JJ; Yamamoto, N | 1 |
| Dagostino, P; Katz, J; Soghomonian, JJ; Wang, H | 1 |
| Allis, JC; Pondé, MP; Spolador, T | 1 |
| Marti, M; Morari, M; Trapella, C; Viaro, R | 1 |
| Durif, F; Fraix, V; Kickler, N; Krack, P; Krainik, A; Lamalle, L; Lebas, JF; Pollak, P; Rémy, C; Segebarth, C | 1 |
| Cenci, MA; Danysz, W; Dekundy, A; Marti, M; Mela, F; Morari, M | 1 |
| Hanajima, R; Nomura, Y; Segawa, M; Ugawa, Y | 1 |
| Bishop, C; Dupre, KB; Eskow, KL; Negron, G | 1 |
| Happe, S; Lanz, M | 1 |
| Allen, RP; Hening, W; Tenzer, P; Winkelman, JW | 1 |
| Encarnacion, EV; Hauser, RA | 1 |
| Aceves, J; Erlij, D; Florán, B; Floran, L; García-Ramírez, M; Rangel-Barajas, C; Sánchez-Lemus, E; Silva, I | 1 |
| Grace, AA | 1 |
| Marti, M; Morari, M; Trapella, C | 1 |
| Killick, R; Wong, K; Yee, B | 1 |
| Savolainen, H | 1 |
| Bielicki, G; Chassain, C; Durif, F; Keller, C; Renou, JP | 1 |
| Aceves, J; Erlij, D; Florán, B; Lopéz-Santiago, LM; Rangel-Barajas, C; Silva, I | 1 |
| Gendelman, HE; Hutter-Saunders, JA; Kosloski, LM; McMillan, JM; Mosley, RL; Rinat, T; Yotam, N | 1 |
| Bassi, MS; Bernardi, G; Fedele, E; Galati, S; Marzetti, F; Peppe, A; Pierantozzi, M; Stanzione, P; Stefani, A; Vitek, J | 1 |
| Bido, S; Marti, M; Morari, M | 1 |
| Bido, S; Cenci, MA; Marti, M; Mela, F; Morari, M | 1 |
| de Biase, S; Gigli, GL; Lorenzut, S; Merlino, G; Valente, M | 1 |
| Aurora, RN; Bista, SR; Casey, KR; Kristo, DA; Lamm, CI; Rosenberg, RS; Rowley, JA; Tracy, SL; Zak, RS | 1 |
| Gluck, MA; Herzallah, MM; Moustafa, AA | 1 |
| Bezard, E; Brambilla, R; Calabresi, P; Fasano, S; Guerrini, R; Li, Q; Marti, M; Morari, M; Morella, I; Rodi, D; Simonato, M; Tozzi, A | 1 |
| Auburger, G; Dehorter, N; Gispert, S; Hammond, C; Klinkenberg, M; Lopez, C; Lozovaya, N; Mdzomba, BJ; Michel, FJ; Tsintsadze, T; Tsintsadze, V | 1 |
| Auberson, YP; Budri, M; Calcagno, M; Dekundy, A; Mabrouk, OS; Mela, F; Morari, M; Parsons, CG; Viaro, R | 1 |
| Chae, Y; Choo, HJ; Doo, AR; Kim, SN; Lee, B; Lee, H; Park, HJ; Park, JJ; Park, JY; Shim, I | 1 |
| Greengard, P; Heiman, M; Heintz, N; Kaplitt, MG; Logan, SM; Musatov, S; Peterson, JD; Sagi, Y; Scarduzio, M; Surmeier, DJ | 1 |
| Afshari, D; Azimi, H; Ghadami, MR; Heidarnejadian, J; Razazian, N | 1 |
| Arcuri, L; Brugnoli, A; Mercatelli, D; Morari, M; Paolone, G | 1 |
| McCreary, AC; Newman-Tancredi, A; Varney, MA | 1 |
| Asensio, MJ; García-Sanz, P; Herranz, AS; Moratalla, R; Solís, O | 1 |
| Shubhakaran, K | 1 |
| Bishop, C; Conti, MM; George, JA; Goldenberg, AA; Lindenbach, D; Melikhov-Sosin, M; Nuss, EE; Ostock, CY | 1 |
| Jo, J; Mousa, SA; Sahli, ZT; Tarazi, FI | 1 |
| Ahmadouk, NA; Gopaluni, S; Sherif, M | 1 |
| Battistini, S; Brusa, L; Caltagirone, C; Di Lorenzo, F; Koch, G; Ponzo, V; Ricci, C; Sambucci, M; Schirinzi, T | 1 |
| Babapour, V; Hashemzadeh, M; Panahi, N; Zendehdel, M | 1 |
| Araki, A; Endo, T; Kazuta, T; Terao, S; Torii, R; Yokoi, K | 1 |
| Blicher, JU; Brooks, DJ; Hansen, KV; Lou, HC; Mouridsen, K; Møller, A; Rømer Thomsen, K | 1 |
| Cuboni, E; Di Giovanni, G; Fedele, E; Galati, S; Grandi, LC; Kaelin-Lang, A; Orban, G; Salvadè, A; Song, W; Stefani, A | 1 |
| Arai, A; Ichinohe, N; Kon, T; Mori, F; Nishijima, H; Okada, M; Suzuki, C; Tomiyama, M; Ueno, S; Wakabayashi, K; Zhu, G | 1 |
| Brugnoli, A; Morari, M; Pisanò, CA | 1 |
| Edden, RAE; Gong, T; Mikkelsen, M; Song, Y; Wang, G; Xiang, Y | 1 |
| Asci, F; Berardelli, A; Bologna, M; D'Onofrio, V; Fabbrini, G; Ferreri, F; Guerra, A | 1 |
| Aguirre-Pérez, A; Alfaro-Rodriguez, A; Arias-Montaño, JA; Avila-Luna, A; Bueno-Nava, A; Gálvez-Rosas, A; Hidalgo-Bravo, A; Ríos, C | 1 |
| Abe, Y; Dantsuji, M; Hata, J; Inoue, T; Matsumoto, M; Mochizuki, A; Nambu, A; Ohno, N; Okano, H; Sano, H; Suematsu, M; Sugiura, Y; Suzuki, T; Taira, S; Takeuchi, H; Tanaka, KF; Watanabe, M; Yagishita, S; Yoshimaru, D | 1 |
34 review(s) available for levodopa and gamma-aminobutyric acid
| Article | Year |
|---|---|
Chemical transmitter systems in the brain.
Topics: Acetylcholine; Brain; Chorea; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Humans; Learning; Levodopa; Memory; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Norepinephrine; Parasympathetic Nervous System; Serotonin; Substantia Nigra; Sympathetic Nervous System; Synapses; Synaptic Transmission | 1975 |
Neurotransmitter interactions related to central dopamine neurons.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Central Nervous System; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Mental Disorders; Neural Pathways; Neurons; Neurotransmitter Agents; Norepinephrine; Parasympathetic Nervous System; Parkinson Disease; Serotonin | 1978 |
Recent advances in research on Parkinsonism.
Topics: Acetylcholinesterase; Adult; Apomorphine; Benserazide; Brain; Bromocriptine; Carbidopa; Dopa Decarboxylase; Dopamine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Selegiline; Serotonin; Substance P; Tyrosine 3-Monooxygenase | 1978 |
[Modulation of dopaminergic receptor sensitivity in the central nervous system: important parameters in synaptic function regulation].
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior; Corpus Striatum; Dogs; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hypothermia; Levodopa; Memory; Mice; Opioid-Related Disorders; Parkinson Disease; Psychotic Disorders; Rats; Receptors, Dopamine; Sleep; Stereotyped Behavior; Substantia Nigra; Synapses; Synaptic Transmission | 1979 |
[Recent neurobiological and related pharmaco-therapeutic acquisitions in Huntington's chorea].
Topics: Amphetamine; Antipsychotic Agents; Brain; Butyrophenones; gamma-Aminobutyric Acid; Humans; Huntington Disease; Kainic Acid; Levodopa; Lithium; Neurotransmitter Agents; Phenothiazines; Sympatholytics; Tetrabenazine | 1979 |
The pharmacology of choreatic movement disorders.
Topics: Acetylcholine; Acute Disease; Amphetamine; Chorea; Dopamine; gamma-Aminobutyric Acid; Hepatolenticular Degeneration; Humans; Huntington Disease; Hyperthyroidism; Levodopa; Lupus Erythematosus, Systemic; Movement Disorders; Serotonin | 1976 |
The pathogensis and medical treatment of extrapyramidal disease.
Topics: Adult; Athetosis; Basal Ganglia Diseases; Caudate Nucleus; Chorea; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Administration Schedule; Dystonia; Female; gamma-Aminobutyric Acid; Glutamates; Haloperidol; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Tic Disorders | 1979 |
Chorea.
Topics: Antipsychotic Agents; Cholinergic Fibers; Chorea; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Reserpine; Serotonin; Somatostatin; Substance P | 1987 |
The pharmacology of myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzodiazepines; Brain; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Levodopa; Muscimol; Myoclonus; Narcotics; Papio; Receptors, GABA-A; Receptors, Opioid; Receptors, Serotonin; Serotonin; Thyrotropin-Releasing Hormone | 1985 |
Effect of tremorigenic agents on the cerebellum: a review of biochemical and electrophysiological data.
Topics: Alkaloids; Animals; Cats; Cerebellar Nuclei; Cerebellum; Cyclic GMP; Diazepam; Dopamine; Electroencephalography; gamma-Aminobutyric Acid; Harmaline; Harmine; Levodopa; Medulla Oblongata; Neural Pathways; Olivary Nucleus; Rabbits; Spinal Cord; Synaptic Transmission; Tremor | 1985 |
The clinical physiology of side effects in long-term L-DOPA therapy.
Topics: Acetylcholine; Basal Ganglia; Brain Chemistry; Brain Stem; Creatinine; Diagnosis, Differential; Dopamine; gamma-Aminobutyric Acid; Humans; Hypothalamus; Levodopa; Movement Disorders; Norepinephrine; Parkinson Disease; Potassium; Receptors, Drug; Serotonin; Sodium; Time Factors | 1974 |
The potential of GABA-mimetics in the therapy of extrapyramidal disorders.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Neurons; Parasympathetic Nervous System; Receptors, Drug | 1980 |
Neuropharmacological actions of GABA agonists: predictability for their clinical usefulness.
Topics: Antipsychotic Agents; Brain Chemistry; Dyskinesia, Drug-Induced; Epilepsy; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Muscular Diseases; Schizophrenia | 1981 |
Current psychopathological theories of tardive dyskinesia and their implications for future research.
Topics: Acetylcholine; Adult; Aged; Animals; Antipsychotic Agents; Brain; Dopamine; Dyskinesia, Drug-Induced; Estrogens; Female; gamma-Aminobutyric Acid; Haplorhini; Humans; Levodopa; Norepinephrine; Parkinson Disease, Secondary; Rats; Receptors, Dopamine; Tyrosine 3-Monooxygenase | 1982 |
Catecholamine systems of retina: a model for studying synaptic mechanisms.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Darkness; Dopamine; Electrophysiology; Enzyme Activation; Epinephrine; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Humans; Levodopa; Light; Melatonin; Narcotics; Neurons; Norepinephrine; Parkinson Disease; Receptors, Adrenergic; Retina; Schizophrenia; Serotonin | 1984 |
[New directions in contemporary pharmacotherapy of parkinsonism (review)].
Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antiparkinson Agents; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Bromocriptine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Levodopa; Lisuride; Oxprenolol; Parkinson Disease; Piracetam; Piribedil; Propranolol | 1984 |
[Biochemical bases of Parkinson disease].
Topics: Acetylcholine; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dopa Decarboxylase; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Selegiline; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1984 |
GABA system, GABA receptor agonists and dyskinesia.
Topics: Basal Ganglia; Cholinergic Fibers; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Movement Disorders; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Presymptomatic and early detection in Huntington's disease.
Topics: Blood Platelets; Electrodiagnosis; Evoked Potentials; Eye Movements; gamma-Aminobutyric Acid; Genetic Carrier Screening; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Monoamine Oxidase; Movement; Neurologic Examination; Psychological Tests; Serotonin | 1980 |
[Biochemical aspects of involuntary movements (author's transl)].
Topics: Adenosine Triphosphate; Brain; Calcium; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Movement Disorders; Norepinephrine; Parkinson Disease; Serotonin | 1981 |
An analysis of sea urchin metamorphosis.
Topics: Animals; Apoptosis; Biological Transport; Chlorophyta; Dopamine; Drug Resistance; Environment; gamma-Aminobutyric Acid; Glutamine; Larva; Levodopa; Metamorphosis, Biological; Mitosis; Nerve Net; Nervous System; Norepinephrine; Sea Urchins | 2000 |
Neurochemical relationships in the action of opioid analgesics on cerebral cortex.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Cats; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Iontophoresis; Levodopa; Neurons; Pain; Thalamus | 2001 |
Tremor.
Topics: Acetates; Amines; Anticonvulsants; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electromyography; Essential Tremor; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Motor Cortex; Muscle, Skeletal; Parkinson Disease; Posture; Primidone; Randomized Controlled Trials as Topic; Severity of Illness Index; Somatosensory Cortex; Topiramate; Tremor | 2003 |
Progress in pursuit of therapeutic A2A antagonists: the adenosine A2A receptor selective antagonist KW6002: research and development toward a novel nondopaminergic therapy for Parkinson's disease.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Clinical Trials as Topic; Corpus Striatum; Disease Models, Animal; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Levodopa; Mice; Mice, Knockout; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Primates; Purines; Rats; Receptor, Adenosine A2A; Receptors, Dopamine D2 | 2003 |
Management of restless legs syndrome in patients on dialysis.
Topics: Amines; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Narcotics; Pramipexole; Renal Dialysis; Restless Legs Syndrome; Thiazoles; Uremia | 2006 |
Treatment of restless legs syndrome.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agents; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Randomized Controlled Trials as Topic; Restless Legs Syndrome | 2006 |
[When the legs have to keep moving at night--the restless legs syndrome].
Topics: Adult; Amines; Analgesics, Opioid; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Polysomnography; Pregnancy; Quality of Life; Restless Legs Syndrome; Sleep Wake Disorders; Time Factors | 2007 |
Restless legs syndrome: nonpharmacologic and pharmacologic treatments.
Topics: Amines; Anemia, Iron-Deficiency; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ferritins; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron; Levodopa; Pramipexole; Restless Legs Syndrome; Trace Elements | 2007 |
Levodopa-induced dyskinesias in Parkinson's disease: etiology, impact on quality of life, and treatments.
Topics: Aged; Animals; Antiparkinson Agents; Basal Ganglia; Corpus Striatum; Deep Brain Stimulation; Dopamine; Dopamine Agonists; Drug Administration Schedule; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Levodopa; Multicenter Studies as Topic; Parkinson Disease; Quality of Life; Receptors, Glutamate; Severity of Illness Index | 2008 |
Physiology of the normal and dopamine-depleted basal ganglia: insights into levodopa pharmacotherapy.
Topics: Antiparkinson Agents; Basal Ganglia; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Neurons; Nucleus Accumbens; Parkinson Disease; Receptors, Dopamine; Synapses; Synaptic Transmission | 2008 |
ADMET considerations for restless leg syndrome drug treatments.
Topics: Amines; Anticonvulsants; Benzothiazoles; Carbamates; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ergolines; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Levodopa; Neuralgia; Pramipexole; Pregabalin; Randomized Controlled Trials as Topic; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome | 2012 |
The treatment of restless legs syndrome and periodic limb movement disorder in adults--an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline.
Topics: Academies and Institutes; Benzothiazoles; Cabergoline; Carbamates; Dopamine Agents; Ergolines; Evidence-Based Medicine; gamma-Aminobutyric Acid; Humans; Indoles; Levodopa; Nocturnal Myoclonus Syndrome; Pergolide; Peripheral Nervous System Diseases; Pramipexole; Restless Legs Syndrome; Sleep Medicine Specialty; United States; Venous Insufficiency | 2012 |
Clinical management of restless legs syndrome in end-stage renal disease patients.
Topics: Amines; Analgesics, Opioid; Benzodiazepines; Benzothiazoles; Comorbidity; Cyclohexanecarboxylic Acids; Dopamine Agonists; Excitatory Amino Acid Antagonists; Exercise Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Intermittent Pneumatic Compression Devices; Kidney Failure, Chronic; Levodopa; Massage; Pramipexole; Quality of Life; Renal Dialysis; Restless Legs Syndrome; Sleep Hygiene; Tetrahydronaphthalenes; Thiophenes | 2017 |
Interventions for chronic kidney disease-associated restless legs syndrome.
Topics: Amines; Anticonvulsants; Ascorbic Acid; Cyclohexanecarboxylic Acids; Dopamine Agonists; Exercise Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron-Dextran Complex; Levodopa; Quality of Life; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Renal Replacement Therapy; Resistance Training; Restless Legs Syndrome; Vitamin E; Vitamins | 2016 |
7 trial(s) available for levodopa and gamma-aminobutyric acid
| Article | Year |
|---|---|
Treatment of Parkinson's disease with sodium valproate: clinical, pharmacological, and biochemical observations.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Valproic Acid | 1979 |
Clinical activity of GABA agonists in neuroleptic- and L-dopa-induced dyskinesia.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Electromyography; gamma-Aminobutyric Acid; Humans; Levodopa | 1985 |
Therapeutic response to progabide in neuroleptic- and L-dopa-induced dyskinesias.
Topics: Adult; Aged; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Placebos | 1987 |
Potentiation of the "dopa" effect in parkinsonism by a direct GABA receptor agonist.
Topics: Anticonvulsants; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; gamma-Aminobutyric Acid; Humans; Levodopa; Parkinson Disease; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study.
Topics: Aged; Animals; Cross-Over Studies; Culture Techniques; Double-Blind Method; Dronabinol; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug | 2001 |
Gabapentin versus levodopa for the treatment of Restless Legs Syndrome in hemodialysis patients: an open-label study.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Male; Middle Aged; Quality of Life; Renal Dialysis; Restless Legs Syndrome; Severity of Illness Index; Treatment Outcome | 2004 |
Gabapentin versus levodopa-c for the treatment of restless legs syndrome in hemodialysis patients: a randomized clinical trial.
Topics: Adult; Aged; Amines; Carbidopa; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Levodopa; Male; Middle Aged; Motor Activity; Renal Dialysis; Restless Legs Syndrome; Sleep; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2015 |
118 other study(ies) available for levodopa and gamma-aminobutyric acid
| Article | Year |
|---|---|
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Neurochemical changes following the administration of precursors of biogenic amines.
Topics: 5-Hydroxytryptophan; Acetylcholine; Amino Acids; Animals; Brain; Choline; Dopamine; gamma-Aminobutyric Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine | 1977 |
[Potential therapeutic activity of GABA-mimetic drugs in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Basal Ganglia Diseases; Bicuculline; Dopamine; Dyskinesia, Drug-Induced; Epilepsy; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Limbic System; Neural Pathways; Neurons; Neurotransmitter Agents; Parkinson Disease; Psychopharmacology | 1979 |
Success and problems of long-term levodopa therapy in Parkinson's disease.
Topics: Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Humans; Levodopa; Motor Neurons; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Serotonin; Time Factors | 1977 |
Rational approaches to the pharmacotherapy of chorea.
Topics: Acetylcholine; Chorea; Dopamine; Drug Evaluation; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Huntington Disease; Levodopa; Norepinephrine; Serotonin | 1976 |
[Regulation of the hypothalamo-pituitary-adrenocortical axis from the aspect of its monitoring using a pharmacological approach].
Topics: Adrenocorticotropic Hormone; Animals; Carbachol; Dogs; gamma-Aminobutyric Acid; Humans; Hypothalamo-Hypophyseal System; Levodopa; Monitoring, Physiologic; Norepinephrine; Pituitary-Adrenal System | 1977 |
On certain relationships between gamma-aminobutyric acid (GABA) and dopaminergic agents in pentylenetetrazol convulsions.
Topics: Amantadine; Animals; Apomorphine; Dextroamphetamine; Ditiocarb; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Haloperidol; Levodopa; Male; Mice; Pentylenetetrazole; Seizures | 1978 |
Apomorphine stereotypies and transmitter mechanisms in the striatum. I. Changes in the apomorphine stereotypies caused by drugs acting on the GABA-ergic, dopaminergic and cholinergic transmission.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Behavior; Corpus Striatum; Diazepam; Ditiocarb; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Levodopa; Male; Methyltyrosines; Mice; Parasympathetic Nervous System; Picrotoxin; Semicarbazides; Stereotyped Behavior; Synaptic Transmission | 1978 |
[Thyrotropin-releasing hormone (TRH): Enhancement of dopamine dependent circling behavior and its own circling-inducing effect in unilateral striatal lesioned animals (author's transl)].
Topics: Animals; Apomorphine; Corpus Striatum; Cyclic AMP; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Levodopa; Male; Mice; Motor Activity; Perfusion; Rats; Rotation; Thyrotropin-Releasing Hormone; Time Factors | 1979 |
[Effects of various amines and amino acids on hypothalamic somatostatin volume].
Topics: 5-Hydroxytryptophan; Amines; Animals; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; Levodopa; Male; Rats; Somatostatin | 1978 |
Cellular accumulation of amines and amino acids in the central ganglia of a gastropod mollusc, Planorbis corneus: an autoradiographic study.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Dopamine; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glycine; Histamine; Levodopa; Mollusca; Neurons; Serotonin; Tyramine | 1978 |
[Neurochemical aspects of Parkinson tremor].
Topics: Antiparkinson Agents; gamma-Aminobutyric Acid; Histamine; Humans; Levodopa; Parkinson Disease, Secondary; Serotonin; Tremor | 1979 |
Effects of L-DOPA on GABA metabolism in chick brain and retina.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Chickens; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Levodopa; Retina | 1979 |
[Sleep: biochemical correlations and pharmacological considerations].
Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Catecholamines; gamma-Aminobutyric Acid; Humans; Levodopa; Peptides; Serotonin; Serotonin Antagonists; Sleep; Vasopressins | 1979 |
Interaction between bromocriptine and levodopa. Biochemical basis for an improved treatment for parkinsonism.
Topics: Animals; Brain; Bromocriptine; Carbidopa; Dopamine; Drug Interactions; Ergolines; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Parkinson Disease; Rats; Serotonin | 1977 |
GABA receptor binding in the parkinsonian brain.
Topics: Aged; Aminobutyrates; Brain; Cerebellar Cortex; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Drug; Substantia Nigra | 1978 |
Effect of chronic neuroleptic or L-DOPA administration on GABA levels in the rat substantia nigra.
Topics: Aminobutyrates; Animals; Clozapine; Dibenzazepines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Haloperidol; Levodopa; Male; Rats; Substantia Nigra | 1977 |
The dopamine hypothesis of schizophrenia. A critical analysis.
Topics: Acetylcholine; Amphetamine; Apomorphine; Cocaine; Dopamine; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Levodopa; Methyldopa; Methyltyrosines; Models, Neurological; Psychoses, Substance-Induced; Schizophrenia; Tranquilizing Agents | 1975 |
Behavioural, biochemical and histological effects of trimethyltin (TMT) induced brain damage in the rat.
Topics: Animals; Aspartate Aminotransferases; Avoidance Learning; Brain; Brain Damage, Chronic; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; L-Lactate Dehydrogenase; Levodopa; Male; Motor Activity; Neurotransmitter Agents; Norepinephrine; Organ Specificity; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Muscarinic; Reference Values; Serotonin; Stereotyped Behavior; Trimethyltin Compounds | 1992 |
Primary receptor for inhibitory transmitters in lamprey spinal cord neurons.
Topics: Animals; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Lampreys; Levodopa; Mathematics; Models, Neurological; Neurons; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine; Taurine | 1992 |
L-dopa stimulates the release of [3H]gamma-aminobutyric acid in the basal ganglia of 6-hydroxydopamine lesioned rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia; Benzazepines; Brain Chemistry; Dopamine Antagonists; gamma-Aminobutyric Acid; Hydrazines; Hydroxydopamines; In Vitro Techniques; Levodopa; Male; Nerve Degeneration; Oxidopamine; Potassium; Rats; Rats, Inbred Strains; Sulpiride; Sympathectomy, Chemical | 1991 |
Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Electrophysiology; gamma-Aminobutyric Acid; Hydroxydopamines; Injections, Intravenous; Iontophoresis; Levodopa; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical | 1990 |
Does GABA act through dopaminergic/cholinergic interaction in the regulation of higher environmental temperature-induced change in body temperature?
Topics: Animals; Body Temperature; Carbidopa; Choline; Cold Temperature; Dopamine; Environment; gamma-Aminobutyric Acid; Levodopa; Male; Muscimol; Neurons; Rats; Temperature | 1990 |
The role of striatopallidal neurones utilizing gamma-aminobutyric acid in the pathophysiology of MPTP-induced parkinsonism in the primate: evidence from [3H]flunitrazepam autoradiography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Carbidopa; Corpus Striatum; Deoxyglucose; Flunitrazepam; gamma-Aminobutyric Acid; Globus Pallidus; Levodopa; Macaca fascicularis; Neurons; Organ Specificity; Parkinson Disease; Parkinson Disease, Secondary; Tritium | 1990 |
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Influence of coexisting hypothalamic messengers on growth hormone secretion from rat anterior pituitary cells in vitro.
Topics: Animals; Cells, Cultured; Dopamine; Galanin; gamma-Aminobutyric Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Hypothalamus; Levodopa; Male; Neurotensin; Peptides; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains | 1987 |
The synthesis and metabolism of catecholamines in the spinal cord of the rat after acute and chronic transections.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Cordotomy; Dopamine; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homovanillic Acid; Levodopa; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord | 1985 |
Acute cyanide intoxication and central transmitter systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Apomorphine; Brain; Cyanides; Cyclic GMP; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Spiperone | 1985 |
Cerebrospinal fluid GABA and homocarnosine concentrations in patients with Friedreich's ataxia, Parkinson's disease, and Huntington's chorea.
Topics: Adult; Aged; Carnosine; Dipeptides; Female; Friedreich Ataxia; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Parkinson Disease | 1987 |
Induction and reversal of dopamine dyskinesia in rat, cat, and monkey.
Topics: Animals; Apomorphine; Brain; Cats; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haplorhini; Humans; Levodopa; Motor Activity; Muscimol; Nomifensine; Piribedil; Rats; Receptors, Dopamine; Receptors, GABA-A; Stereotyped Behavior | 1985 |
Animal models of myoclonus using 1,2-dihydroxybenzene (catechol) and chloralose.
Topics: Acetylcholine; Animals; Brain; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Chloralose; Disease Models, Animal; Electromyography; Evoked Potentials; Female; gamma-Aminobutyric Acid; Glycolysis; Levodopa; Monoamine Oxidase Inhibitors; Myoclonus; Rats; Reserpine | 1986 |
[Trial use of L-dopa associated with a dopa-decarboxylase inhibitor in Parkinson's syndrome].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Diphenhydramine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Histamine H1 Antagonists; Levodopa; Parasympatholytics; Parkinson Disease, Secondary; Trihexyphenidyl | 1974 |
Low CSF GABA in Parkinsonian patients who respond poorly to therapy or suffer from the "on-off" phenomenon.
Topics: Antiparkinson Agents; Bromocriptine; Carbidopa; Ergolines; Female; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prognosis; Radioligand Assay | 1982 |
Role of the relationships between the neurotransmitter systems in the convulsive-seizure reactions.
Topics: 5-Hydroxytryptophan; Amantadine; Amphetamine; Animals; Dopamine; Electroshock; gamma-Aminobutyric Acid; Kindling, Neurologic; Levodopa; Mice; Neurotransmitter Agents; Rats; Seizures; Serotonin | 1982 |
Chairman's introduction: role of the pallidum and its transmitters in the therapy of parkinsonian rigidity and akinesia.
Topics: Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Levodopa; Neurotransmitter Agents; Parkinson Disease; Receptors, Dopamine; Stereotaxic Techniques | 1984 |
Neurotransmitters and epilepsy: distinguishing characteristics and unifying precepts.
Topics: Animals; Brain; Disease Models, Animal; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Kindling, Neurologic; Levodopa; Mice; Neurotransmitter Agents; Norepinephrine; Papio; Rats; Seizures; Serotonin | 1984 |
The effect of acute ethanol on dopamine metabolism and other neurotransmitters in the hypothalamus and the corpus striatum of mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; gamma-Aminobutyric Acid; Homovanillic Acid; Hypothalamus; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Norepinephrine | 1984 |
Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs.
Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hypoxia; Levodopa; Middle Aged; Myoclonus | 1980 |
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures | 1980 |
Involvement of central GABA receptors in the regulation of the urinary bladder function of anaesthetized rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Glycine; Levodopa; Male; Muscimol; Muscle Contraction; Rats; Receptors, Cell Surface; Urinary Bladder | 1980 |
Studies on possible mechanisms of action of electroconvulsive therapy; effects of repeated electrically induced seizures on rat brain receptors for monoamines and other neurotransmitters.
Topics: Animals; Brain Chemistry; Dihydroalprenolol; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Levodopa; Norepinephrine; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Serotonin; Tranylcypromine | 1981 |
Human growth hormone and dopaminergic drugs, with special reference to deprenyl (selegiline): a summary of studies on volunteers.
Topics: Apomorphine; Bromocriptine; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Phenethylamines; Receptors, Dopamine; Selegiline; Synapses | 1983 |
Levels of gamma-aminobutyric acid in cerebrospinal fluid in various neurologic disorders.
Topics: Brain Chemistry; Cerebellar Diseases; Creatine Kinase; Dementia; Diet; Encephalitis; Epilepsy; gamma-Aminobutyric Acid; Humans; Huntington Disease; Hypoxia; Levodopa; Multiple Sclerosis; Muscular Dystrophies; Nervous System Diseases; Parkinson Disease; Tissue Preservation | 1980 |
CSF GABA levels in Parkinson's disease.
Topics: Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Parkinson Disease; Probenecid | 1984 |
Effects of some gamma-aminobutyric acid (GABA)-ergic drugs on the dopaminergic control of human growth hormone secretion.
Topics: Adult; Apomorphine; Baclofen; Diazepam; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Male; Valproic Acid | 1980 |
Symptomatic treatment of tardive dyskinesia: a word of caution.
Topics: Animals; Brain; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Haplorhini; Humans; Levodopa; Muscimol; Rats; Receptors, Cholinergic; Receptors, Dopamine | 1981 |
Interrelations between dopaminergic and GABA-ergic transmitter mechanisms in apomorphine stereotypy.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Levodopa; Male; Picrotoxin; Rats; Stereotyped Behavior; Valproic Acid | 1982 |
Low CSF gamma-aminobutyric acid levels in Parkinson's Disease. Effect of levodopa and carbidopa.
Topics: Aged; Carbidopa; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1982 |
Dose-conductance relationships for GABA agonists and the effect of uptake inhibitors in crayfish stretch receptor neurons.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Levodopa; Mechanoreceptors; Muscimol; Neurons | 1981 |
Concomitant increases in serum growth hormone and hypothalamic somatostatin in rats after injection of gamma-aminobutyric acid, aminooxyacetic acid, or gamma-hydroxybutyric acid.
Topics: Acetates; Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; Growth Hormone; Hydroxybutyrates; Hypothalamus; Levodopa; Male; Rats; Somatostatin | 1980 |
Relations between dopaminergic and GABAergic mechanisms in avian brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Apomorphine; Brain; Chickens; Ethanolamines; gamma-Aminobutyric Acid; Injections, Intraventricular; Levodopa | 1980 |
Higher environmental temperature-induced increase of body temperature: involvement of central opioidergic-GABAergic interaction.
Topics: Animals; Body Temperature; Body Temperature Regulation; Carbidopa; Dopamine Agents; Dopamine Antagonists; Endorphins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Haloperidol; Hot Temperature; Levodopa; Male; Narcotic Antagonists; Parasympathetic Nervous System; Rats; Receptors, Opioid | 1995 |
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Mice; Mice, Inbred BALB C; Seizures; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice.
Topics: Animals; Bicuculline; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Pyrimethamine; Seizures | 1994 |
Effects of drug manipulations on anterior components of somatosensory evoked potentials in a parkinsonian animal model.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cholinergic Antagonists; Electric Stimulation; Electrophysiology; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Levodopa; Macaca fascicularis; Median Nerve; Norepinephrine; Parkinson Disease, Secondary; Receptors, N-Methyl-D-Aspartate | 1994 |
Roles of dopamine and its receptors in generation of choreic movements.
Topics: Afferent Pathways; Animals; Brain Mapping; Cerebral Cortex; Choline O-Acetyltransferase; Chorea; Corpus Striatum; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Levodopa; Macaca; Neurons; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase | 1993 |
Muscle cramp as the result of impaired GABA function--an electrophysiological and pharmacological observation.
Topics: Amyotrophic Lateral Sclerosis; Baclofen; Clomipramine; Diazepam; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Levodopa; Lidocaine; Male; Middle Aged; Motor Neurons; Muscle Cramp; Muscular Atrophy, Spinal; Nerve Block; Neural Conduction; Sensory Thresholds; Ulnar Nerve | 1993 |
Acidic fibroblast growth factor and catecholamines synergistically up-regulate tyrosine hydroxylase activity in developing and damaged dopamine neurons in culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Catecholamines; Cells, Cultured; Dopamine; Embryo, Mammalian; Fibroblast Growth Factor 1; gamma-Aminobutyric Acid; Kinetics; Levodopa; Mesencephalon; Neurons; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Rats; Serotonin; Tyrosine 3-Monooxygenase | 1996 |
Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats?
Topics: Afferent Pathways; alpha-Methyltyrosine; Animals; gamma-Aminobutyric Acid; Hypertension; Levodopa; Microdialysis; Neurotransmitter Agents; Phenylephrine; Potassium; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Solitary Nucleus; Tetrodotoxin | 1998 |
Modulatory effects of L-DOPA on D2 dopamine receptors in rat striatum, measured using in vivo microdialysis and PET.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Globus Pallidus; Hydrazines; Kinetics; Levodopa; Male; Microdialysis; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides; Time Factors; Tomography, Emission-Computed | 1998 |
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Binding, Competitive; Bradycardia; Dopamine Agents; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hypotension; Levodopa; Male; Microinjections; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus; Tritium | 1999 |
The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus | 1999 |
Increased striatal expression of glutamate decarboxylase 67 after priming of 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Isoenzymes; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Time Factors; Transcription, Genetic | 1999 |
Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Idazoxan; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Norepinephrine; Parkinson Disease | 2000 |
Muscarinic antagonists in substantia nigra influence the decarboxylation of L-dopa in striatum.
Topics: Analysis of Variance; Animals; Corpus Striatum; Decarboxylation; Diamines; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Muscarinic Antagonists; Neurotransmitter Agents; Parasympatholytics; Perfusion; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Substantia Nigra; Time Factors; Trihexyphenidyl | 2000 |
Neurobiology of the ventral basal ganglia loop.
Topics: Basal Ganglia; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Levodopa; Receptors, N-Methyl-D-Aspartate | 2000 |
Inhibition by L-3,4-dihydroxyphenylalanine of hippocampal CA1 neurons with facilitation of noradrenaline and gamma-aminobutyric acid release.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Bicuculline; Dopamine Agents; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Levodopa; Male; Neurons; Norepinephrine; Phentolamine; Rats; Rats, Wistar | 2001 |
Regulation of Na(+) transport across leech skin by peptide hormones and neurotransmitters.
Topics: Amiloride; Angiotensin II; Animals; Arginine Vasopressin; Biological Transport; Cyclic AMP; Dopamine; gamma-Aminobutyric Acid; Invertebrate Hormones; Leeches; Levodopa; Lypressin; Lysine; Nerve Tissue Proteins; Neurotransmitter Agents; Oxytocin; Serotonin; Skin; Sodium; Vasopressins | 2001 |
Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action.
Topics: 4-Aminopyridine; Animals; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Hypoglycemic Agents; Levodopa; Male; Membrane Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, GABA-B; Receptors, Presynaptic; Serotonin; Synaptic Transmission; Tolbutamide | 2002 |
Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Bicuculline; Cholinergic Fibers; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Levodopa; Macaca mulatta; Male; Motor Activity; Neural Inhibition; Neural Pathways; Parkinsonian Disorders; Pons; Receptors, GABA-A; Recovery of Function; Tegmentum Mesencephali; Treatment Outcome | 2002 |
Stimulation of cannabinoid receptors reduces levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benserazide; Callithrix; Corpus Striatum; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Globus Pallidus; Levodopa; Male; Motor Skills; Parkinsonian Disorders; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism.
Topics: Amphetamine; Amphetamines; Animals; Cell Membrane; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred C57BL; Neurons; Quinpirole; Time Factors | 2003 |
L-DOPA-induced modulation of GABA and glutamate release in substantia nigra pars reticulata in a rodent model of Parkinson's disease.
Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2004 |
Therapeutic doses of L-dopa reverse hypersensitivity of corticostriatal D2-dopamine receptors and glutamatergic overactivity in experimental parkinsonism.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Dopamine Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Models, Animal; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Transmission | 2004 |
Restless legs syndrome: clinical experience with long-term treatment.
Topics: Adult; Aged; Amines; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Long-Term Care; Male; Middle Aged; Narcotics; Prospective Studies; Restless Legs Syndrome; Treatment Outcome | 2004 |
Expression of GAD65 and GAD67 immunoreactivity in MPTP-treated monkeys with or without L-DOPA administration.
Topics: Animals; Basal Ganglia; Cell Count; Cerebral Cortex; Disease Models, Animal; Dopamine Agents; gamma-Aminobutyric Acid; Globus Pallidus; Glutamate Decarboxylase; Immunohistochemistry; Isoenzymes; Levodopa; Male; Neural Inhibition; Neurons; Parkinsonian Disorders; Saimiri; Transcriptional Activation; Up-Regulation | 2005 |
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
Topics: Animals; Arachidonic Acids; Callithrix; Cannabinoid Receptor Modulators; Dyskinesia, Drug-Induced; Endocannabinoids; Female; gamma-Aminobutyric Acid; Glycerides; Levodopa; Male; MPTP Poisoning; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2005 |
L-DOPA inhibits depolarization-induced [3H]GABA release in the dopamine-denervated globus pallidus of the rat: the effect is dopamine independent and mediated by D2-like receptors.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Data Interpretation, Statistical; Decarboxylation; Denervation; Dopamine; Dopamine Agents; Dopamine Antagonists; Enzyme Inhibitors; gamma-Aminobutyric Acid; Globus Pallidus; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride; Sympathectomy, Chemical; Sympatholytics | 2006 |
Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata.
Topics: Animals; Antiparkinson Agents; Dopamine; Dopamine Agents; Drug Administration Schedule; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2006 |
Unilateral 6-hydroxydopamine lesion of dopamine neurons and subchronic L-DOPA administration in the adult rat alters the expression of the vesicular GABA transporter in different subsets of striatal neurons and in the substantia nigra, pars reticulata.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Down-Regulation; Drug Administration Schedule; Enkephalins; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Synaptic Transmission; Up-Regulation; Vesicular Inhibitory Amino Acid Transport Proteins | 2007 |
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Bicuculline; Drug Synergism; Drug Therapy, Combination; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections; Levodopa; Male; Microdialysis; Motor Activity; Neural Pathways; Nociceptin Receptor; Oxidopamine; Parkinsonian Disorders; Perfusion; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium Channel Blockers; Stereotaxic Techniques; Substantia Nigra; Tetrodotoxin; Thalamus | 2007 |
Glutamate measurement in Parkinson's disease using MRS at 3 T field strength.
Topics: Antiparkinson Agents; Aspartic Acid; Corpus Striatum; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Levodopa; Magnetic Resonance Spectroscopy; Parkinson Disease; Reference Values | 2007 |
Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Brain; Disease Models, Animal; Drug Interactions; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Microdialysis; Neural Inhibition; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Substantia Nigra; Synaptic Transmission | 2007 |
Intracortical inhibition of the motor cortex in Segawa disease (DYT5).
Topics: Adult; Basal Ganglia; Biopterins; Brain Diseases, Metabolic; Diagnosis, Differential; Dopamine; Dopamine Agents; Dystonic Disorders; Evoked Potentials, Motor; Female; gamma-Aminobutyric Acid; GTP Cyclohydrolase; Humans; Interneurons; Levodopa; Male; Middle Aged; Motor Cortex; Muscle, Skeletal; Neural Inhibition; Neural Pathways; Phenotype; Transcranial Magnetic Stimulation | 2007 |
The differential effects of 5-HT(1A) receptor stimulation on dopamine receptor-mediated abnormal involuntary movements and rotations in the primed hemiparkinsonian rat.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Agents; Drug Interactions; Dyskinesias; gamma-Aminobutyric Acid; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine; Serotonin Receptor Agonists; Stereotyped Behavior; Triglycerides | 2007 |
6-OHDA-induced hemiparkinsonism and chronic L-DOPA treatment increase dopamine D1-stimulated [(3)H]-GABA release and [(3)H]-cAMP production in substantia nigra pars reticulata of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Cyclic AMP; Disease Models, Animal; Dopamine Agents; Functional Laterality; gamma-Aminobutyric Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Receptors, Dopamine D1; Substantia Nigra; Time Factors; Tritium | 2008 |
The novel nociceptin/orphanin FQ receptor antagonist Trap-101 alleviates experimental parkinsonism through inhibition of the nigro-thalamic pathway: positive interaction with L-DOPA.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Motor Activity; Narcotic Antagonists; Neural Pathways; Nociceptin Receptor; Oxidopamine; Parkinsonian Disorders; Psychomotor Performance; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Substantia Nigra; Thalamus; Time Factors | 2008 |
Restless legs syndrome.
Topics: Algorithms; Amines; Analgesics, Opioid; Benzodiazepines; Carbidopa; Causality; Cyclohexanecarboxylic Acids; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Levodopa; Middle Aged; Oxycodone; Practice Guidelines as Topic; Restless Legs Syndrome; Treatment Outcome | 2009 |
High toxicity of hydrogen sulfide by the inhibition of mitochondrial respiration.
Topics: Animals; Antioxidants; Cell Respiration; Dopamine; Electron Transport Complex IV; gamma-Aminobutyric Acid; Hydrogen Sulfide; Levodopa; Lipid Peroxidation; Mitochondria; Neuroglia; Rats | 2010 |
Metabolic changes detected in vivo by 1H MRS in the MPTP-intoxicated mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Dopamine Agents; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Levodopa; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurotoxins; Protons | 2010 |
L-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata.
Topics: Adenylyl Cyclases; Animals; Dyskinesia, Drug-Induced; Enzyme Inhibitors; gamma-Aminobutyric Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Severity of Illness Index; Substantia Nigra; Up-Regulation | 2011 |
BL-1023 improves behavior and neuronal survival in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice.
Topics: Animals; Behavior, Animal; Brain; Cell Survival; Drug Combinations; gamma-Aminobutyric Acid; Immunohistochemistry; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Neuroprotective Agents; Parkinsonian Disorders | 2011 |
The clinical efficacy of L-DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus.
Topics: Aged; Antiparkinson Agents; Cyclic GMP; Deep Brain Stimulation; gamma-Aminobutyric Acid; Humans; Levodopa; Middle Aged; Parkinson Disease; Statistics, Nonparametric; Subthalamic Nucleus; Thalamus | 2011 |
Amantadine attenuates levodopa-induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels.
Topics: Amantadine; Animals; Antiparkinson Agents; Behavior, Animal; Data Interpretation, Statistical; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Hydroxydopamines; Levodopa; Male; Mice; Microdialysis; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2011 |
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels.
Topics: Animals; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Microdialysis; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 2012 |
Dissociating the cognitive effects of levodopa versus dopamine agonists in a neurocomputational model of learning in Parkinson's disease.
Topics: Animals; Basal Ganglia; Cognition; Dopamine Agonists; Dopaminergic Neurons; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Learning; Levodopa; Memory; Models, Neurological; Parkinson Disease; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2013 |
Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias.
Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Autoradiography; Behavior, Animal; Dyskinesia, Drug-Induced; Electrophysiological Phenomena; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Macaca; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Microinjections; Nociceptin; Opioid Peptides; Oxidopamine; Postural Balance; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2012 |
Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Electric Conductivity; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Kainic Acid; Levodopa; Male; Mice; Mice, Knockout; Neurons; Parkinsonian Disorders; Patch-Clamp Techniques; Protein Kinases; Subthalamic Nucleus | 2012 |
GluN2A and GluN2B NMDA receptor subunits differentially modulate striatal output pathways and contribute to levodopa-induced abnormal involuntary movements in dyskinetic rats.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Phenols; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 2013 |
Combined treatment with acupuncture reduces effective dose and alleviates adverse effect of L-dopa by normalizing Parkinson's disease-induced neurochemical imbalance.
Topics: Acupuncture Therapy; Animals; Antiparkinson Agents; Brain Chemistry; Combined Modality Therapy; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Movement; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Substantia Nigra | 2014 |
Nitric oxide regulates synaptic transmission between spiny projection neurons.
Topics: Animals; Axons; Basal Ganglia; Cyclic AMP; Dopamine; Electrophysiology; Feedback, Physiological; Female; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Guanylate Cyclase; Levodopa; Male; Mice; Neuronal Plasticity; Neurons; Nitric Oxide; Oxidopamine; Signal Transduction; Synaptic Transmission; Vesicular Inhibitory Amino Acid Transport Proteins | 2014 |
Eltoprazine prevents levodopa-induced dyskinesias by reducing striatal glutamate and direct pathway activity.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Levodopa; Male; MAP Kinase Signaling System; Motor Activity; Oxidopamine; Parkinson Disease; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Time Factors | 2015 |
The novel 5-HT1A receptor agonist, NLX-112 reduces l-DOPA-induced abnormal involuntary movements in rat: A chronic administration study with microdialysis measurements.
Topics: Animals; Anti-Dyskinesia Agents; Corpus Striatum; Cross-Over Studies; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Parkinsonian Disorders; Piperidines; Pyridines; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2016 |
L-DOPA Reverses the Increased Free Amino Acids Tissue Levels Induced by Dopamine Depletion and Rises GABA and Tyrosine in the Striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Forelimb; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Levodopa; Mice; Oxidopamine; Rotarod Performance Test; Taurine; Tyrosine | 2016 |
Restless leg syndrome and its treatment.
Topics: Amines; Carbidopa; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Renal Dialysis; Restless Legs Syndrome | 2016 |
The Role of Primary Motor Cortex (M1) Glutamate and GABA Signaling in l-DOPA-Induced Dyskinesia in Parkinsonian Rats.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Motor Cortex; Movement; Oxidopamine; Parkinsonian Disorders; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Signal Transduction; Sympatholytics; Tardive Dyskinesia | 2016 |
Impaired intracortical transmission in G2019S leucine rich-repeat kinase Parkinson patients.
Topics: Aged; Antiparkinson Agents; Case-Control Studies; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Long-Term Potentiation; Male; Middle Aged; Motor Cortex; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Parkinson Disease; Synaptic Transmission; Transcranial Magnetic Stimulation | 2017 |
Interaction between central GABAA receptor and dopaminergic system on food intake in neonatal chicks: role of D
Topics: Adrenergic Agents; Analysis of Variance; Animals; Animals, Newborn; Benzazepines; Chickens; Dopamine; Dopamine Agents; Eating; Female; Food Deprivation; GABA Agents; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Levodopa; Oxidopamine; Receptors, Dopamine D1; Receptors, GABA-A | 2018 |
Effectiveness of levodopa treatment for diabetic chorea with reduced striatal accumulation in dopamine transporter SPECT: a case report.
Topics: Aged; Amines; Chorea; Corpus Striatum; Cyclohexanecarboxylic Acids; Diabetes Complications; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Levodopa; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2017 |
Attenuation of dopamine-induced GABA release in problem gamblers.
Topics: Adult; Azides; Benzodiazepines; Dopamine; Dopamine Agents; Double-Blind Method; Frontal Lobe; Gambling; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Positron-Emission Tomography; Self-Control; Synaptic Transmission | 2019 |
Acute and Chronic Dopaminergic Depletion Differently Affect Motor Thalamic Function.
Topics: Adrenergic Agents; Animals; Basal Ganglia; Cerebral Cortex; Deep Brain Stimulation; Dopamine; Dopamine Agents; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Levodopa; Male; Medial Forebrain Bundle; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Thalamus | 2020 |
GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming.
Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Levodopa; Male; Neuronal Plasticity; Neurons; Parkinsonian Disorders; Rats; Rats, Wistar; Synaptic Transmission | 2020 |
Striatal and nigral muscarinic type 1 and type 4 receptors modulate levodopa-induced dyskinesia and striato-nigral pathway activation in 6-hydroxydopamine hemilesioned rats.
Topics: Allosteric Regulation; Animals; Dopamine Agents; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Microdialysis; Muscarinic Antagonists; Neostriatum; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Substantia Nigra; Sympatholytics | 2020 |
Single-dose L-dopa increases upper brainstem GABA in Parkinson's disease: A preliminary study.
Topics: Brain Stem; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Parkinson Disease | 2021 |
Assessing the interaction between L-dopa and γ-transcranial alternating current stimulation effects on primary motor cortex plasticity in Parkinson's disease.
Topics: Dopamine; Evoked Potentials, Motor; gamma-Aminobutyric Acid; Humans; Levodopa; Motor Cortex; Neuronal Plasticity; Parkinson Disease; Transcranial Direct Current Stimulation; Transcranial Magnetic Stimulation | 2023 |
Chronic H
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Oxidopamine; Rats; RNA, Messenger | 2023 |
Shared GABA transmission pathology in dopamine agonist- and antagonist-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Dopamine; Dopamine Agonists; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Levodopa; Mice; Oxidopamine; Parkinsonian Disorders | 2023 |