Page last updated: 2024-08-17

levodopa and folic acid

levodopa has been researched along with folic acid in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	22 (55.00)	29.6817
2010's	13 (32.50)	24.3611
2020's	3 (7.50)	2.80

Authors

Authors	Studies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fedotova, OI; Frol'kis, AV	1
Butler, IJ; Irons, M; Kaufman, S; Langlais, PJ; Levy, HL; Milstien, S; O'Flynn, ME; Stack, CV	1
Kowa, H; Nakashima, K; Nakaso, K; Takeshima, T; Yasui, K	1
Diaz-Arrastia, R; Frol, AB; Rogers, JD; Sanchez-Saffon, A	1
Kuhn, W; Müller, T; Woitalla, D	2
Feldman, RG; Miller, JW; Nadeau, MR; Selhub, J; Thomas, CA; Wolf, PA	1
Armenise, E; de Mari, M; Fraddosio, A; Iliceto, G; Lamberti, P; Livrea, P; Zoccolella, S	1
Bottiglieri, T; Dewey, RB; Diaz-Arrastia, R; O'Suilleabhain, PE; Sharma, S	1
Armenise, E; de Mari, M; Fraddosio, A; Iliceto, G; Lamberti, P; Lamberti, SV; Livrea, P; Mastronardi, R; Zoccolella, S	1
Armenise, E; de Mari, M; Fraddosio, A; Iliceto, G; Lamberti, P; Lamberti, SV; Livrea, P; Zoccolella, S	1
Benetin, J; Blazícek, P; Gmitterová, K; Kukumberg, P; Valkovic, P; Valkovicová, L	1
Bottiglieri, T; Diaz-Arrastia, R; Greenberg, SM; Growdon, JH; Gurol, ME; Hyman, BT; Irizarry, MC; Locascio, JJ; Raju, S; Tennis, M	1
Barcikowska, M; Chodakowska-Zebrowska, M; Czyzewski, K; Lokk, J; Peplonska, B; Religa, D; Stepien, K; Styczynska, M; Winblad, B	1
Camicioli, R; Espay, AJ; Lafontaine, AL; Lang, AE; Martin, WR; Postuma, RB; Ranawaya, R; Suchowersky, O; Zadikoff, C	1
Aydemir, T; Cetin, S; Hanoglu, L; Koldas, M; Meral, H; Ozer, F; Ozturk, O; Seval, H; Yilsen, M	1
Di Rocco, A; Werner, P	1
Angelopoulos, E; Boufidou, F; Evangelopoulos, ME; Kararizou, E; Nikolaou, C; Triantafyllou, NI; Tsounis, S; Vassilopoulos, D	1
Armstrong, VW; Bachmann, CG; Guth, N; Happe, S; Helmschmied, K; Paulus, W	1
Belcastro, V; Caccamo, D; Calabresi, P; Currò, M; Di Iorio, W; Gorgone, G; Ientile, R; Menichetti, C; Parisi, G; Parnetti, L; Pisani, F; Rossi, A	1
Angelopoulos, E; Boufidou, F; Evangelopoulos, ME; Kararizou, E; Nikolaou, C; Rentzos, M; Triantafyllou, NI; Vassilopoulos, D	1
Bouchard, TP; Camicioli, RM; Somerville, MJ	1
Barchak, AG; Busanello, EN; Camargo, D; Carrion, MJ; da Costa, JC; Dalbem, A; de Mello Rieder, CR; de Sousa Miguel, SR; dos Santos, EF; Miglioranza, A; Rosa, C; Saute, J; Vargas, CR; Wajner, M; Zanatta, A	1
de la Fuente-Fernández, R; Grande, M; Llaneza, M; Macías, M; Santos-García, D	1
Juzeniene, A; Moan, J; Nielsen, KP	1
Belcastro, V; Caccamo, D; Calabresi, P; Currò, M; Ferlazzo, N; Gorgone, G; Ientile, R; Parisi, G; Parnetti, L; Pisani, F; Rossi, A; Tambasco, N	1
Martey, J; Rajabally, YA	1
Nyholm, D; Rahne, KE; Tagesson, C	1
Antonini, A; Calandrella, D; Cantello, R; Coletti Moja, M; Comi, C; Dal Fante, M; Lacerenza, M; Mancini, F; Manfredi, L; Oggioni, GD; Pacchetti, C; Riboldazzi, G; Tunesi, S	1
Ghodsi, J; Rafati, AA; Shoja, Y	1
Feng, H; Peng, S; Xiao, J; Xie, Y; Zhang, J	1
Jadavji, NM; Murray, LK	1
Ares-Pensado, B; Castro, A; Fernandez-Pajarin, G; Rivero-de-Aguilar, A; Sesar, A	1
Havaldar, DV; Moholkar, DN; Pawar, KD; Sadalage, PS	1
Anamnart, C; Kitjarak, R	1
de Almeida, AG; Finsterer, J; Rodrigues, AM; Scorza, CA; Scorza, FA	1

Reviews

2 review(s) available for levodopa and folic acid

Article	Year
Association of plasma homocysteine, vitamin B12 and folate levels with cognitive function in Parkinson's disease: A meta-analysis. Neuroscience letters, 2017, 01-01, Volume: 636 Topics: Adult; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Vitamin B 12	2017
The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms. Nutrition research reviews, 2019, Volume: 32, Issue:2 Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex	2019

Article

Year

Association of plasma homocysteine, vitamin B12 and folate levels with cognitive function in Parkinson's disease: A meta-analysis.

Neuroscience letters, 2017, 01-01, Volume: 636

Topics: Adult; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Vitamin B 12

2017

The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms.

Nutrition research reviews, 2019, Volume: 32, Issue:2

Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex

2019

Trials

10 trial(s) available for levodopa and folic acid

Article	Year
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. Neurology, 2003, Apr-08, Volume: 60, Issue:7 Topics: Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Linear Models; Male; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex	2003
Effects of levodopa and COMT inhibitors on plasma homocysteine in Parkinson's disease patients. Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:1 Topics: Aged; Antiparkinson Agents; Case-Control Studies; Catechols; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Levodopa; Linear Models; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12	2005
Plasma homocysteine levels in Parkinson's disease: role of antiparkinsonian medications. Parkinsonism & related disorders, 2005, Volume: 11, Issue:2 Topics: Aged; Antiparkinson Agents; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12	2005
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study. Neurology, 2006, Jun-27, Volume: 66, Issue:12 Topics: Aged; Antiparkinson Agents; Canada; Catechols; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Placebo Effect; Treatment Outcome; United States; Vitamin B 12; Vitamins	2006
Plasma homocysteine levels in patients treated with levodopa: motor and cognitive associations. Neurological research, 2006, Volume: 28, Issue:8 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Case-Control Studies; Cognition; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Motor Activity; Neuropsychological Tests; Parkinson Disease; Statistics, Nonparametric; Vitamin B 12	2006
The influence of levodopa and the COMT inhibitor on serum vitamin B12 and folate levels in Parkinson's disease patients. European neurology, 2007, Volume: 58, Issue:2 Topics: Aged; Analysis of Variance; Antiparkinson Agents; Case-Control Studies; Catechols; Female; Folic Acid; Humans; Immunoassay; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12	2007
Folate and vitamin B12 levels in levodopa-treated Parkinson's disease patients: their relationship to clinical manifestations, mood and cognition. Parkinsonism & related disorders, 2008, Volume: 14, Issue:4 Topics: Affect; Aged; Aged, 80 and over; Analysis of Variance; Antiparkinson Agents; Case-Control Studies; Cognition; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Vitamin B 12	2008
Immediate pigment darkening: its evolutionary roles may include protection against folate photosensitization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:3 Topics: Animals; Biological Evolution; Dermis; Folic Acid; Forearm; Hominidae; Humans; Levodopa; Light; Photolysis; Riboflavin; Skin; Skin Pigmentation; Spectrophotometry; Sunlight; Tetrahydrofolates; Tropical Climate; Ultraviolet Rays; Uroporphyrins	2012
Effects of vitamin B12, folate, and entacapone on homocysteine levels in levodopa-treated Parkinson's disease patients: A randomized controlled study. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 88 Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Research Design; Vitamin B 12	2021
Parkinson's disease: Research puts spotlight on thiamine deficiency and cardiovascular health. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 93 Topics: Folic Acid; Homocysteine; Humans; Levodopa; Parkinson Disease; Thiamine Deficiency; Vitamin B 12	2021

Other Studies

28 other study(ies) available for levodopa and folic acid

Article	Year
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
[Effect of various drugs on membrane digestion]. Klinicheskaia meditsina, 1979, Volume: 57, Issue:7 Topics: Aminophylline; Depression, Chemical; Digestion; Ephedrine; Folic Acid; Humans; Intestinal Mucosa; Jejunum; Levodopa; Nandrolone; Phenobarbital; Prednisolone; Prenylamine; Stimulation, Chemical; Sulfasalazine	1979
Folinic acid therapy in treatment of dihydropteridine reductase deficiency. The Journal of pediatrics, 1987, Volume: 110, Issue:1 Topics: 5-Hydroxytryptophan; Brain; Carbidopa; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Infant, Newborn; Leucovorin; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias	1987
Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD. Neurology, 2000, Aug-08, Volume: 55, Issue:3 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Cysteine; Female; Folic Acid; Genotype; Homocysteine; Humans; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Parkinson Disease; Point Mutation	2000
Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease. Archives of neurology, 2003, Volume: 60, Issue:1 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors; Vitamin B 12	2003
Benefit of folic acid supplementation in parkinsonian patients treated with levodopa. Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:4 Topics: Antiparkinson Agents; Drug Therapy, Combination; Folic Acid; Hematinics; Humans; Levodopa; Parkinson Disease; Risk Assessment	2003
MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease. Journal of neural transmission. Supplementum, 2004, Issue:68 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cytosine; Female; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Tetrahydrofolates; Thymine	2004
Modest increase in plasma homocysteine follows levodopa initiation in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:12 Topics: Aged; Antiparkinson Agents; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Middle Aged; Parkinson Disease; Prospective Studies; Vitamin B 12	2004
Hyperhomocysteinemia in L-dopa treated Parkinson's disease patients: effect of cobalamin and folate administration. European journal of neurology, 2005, Volume: 12, Issue:5 Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12	2005
Reduced plasma homocysteine levels in levodopa/entacapone treated Parkinson patients. Parkinsonism & related disorders, 2005, Volume: 11, Issue:4 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Sectional Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12	2005
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology, 2005, Nov-08, Volume: 65, Issue:9 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12	2005
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease. Neuroscience letters, 2006, Aug-14, Volume: 404, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Reference Values; Vitamin B 12	2006
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study. Neurology, 2007, Apr-24, Volume: 68, Issue:17 Topics: Antiparkinson Agents; Carbon; Catechol O-Methyltransferase Inhibitors; Catechols; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Nitriles; Parkinson Disease; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Time Factors; Vitamin B 12; Vitamin B 6	2007
Homocysteine in restless legs syndrome. Sleep medicine, 2008, Volume: 9, Issue:4 Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Reference Values; Restless Legs Syndrome; Vitamin B 12; Vitamin B 6	2008
Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients. Neuromolecular medicine, 2007, Volume: 9, Issue:3 Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Vitamin B 12	2007
Homocysteine is not associated with global motor or cognitive measures in nondemented older Parkinson's disease patients. Movement disorders : official journal of the Movement Disorder Society, 2009, Jan-30, Volume: 24, Issue:2 Topics: Aged; Antiparkinson Agents; Cognition; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Inactivation, Metabolic; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Motor Skills; Neuropsychological Tests; Parkinson Disease; Severity of Illness Index; Vitamin B Complex	2009
Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease. Metabolic brain disease, 2009, Volume: 24, Issue:2 Topics: Analysis of Variance; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Middle Aged; Nerve Degeneration; Parkinson Disease; Reference Values; Statistics, Nonparametric; Vitamin B 12	2009
Serum vitamin B(12) and folate levels in Parkinson's disease patients treated with duodenal levodopa infusion. Movement disorders : official journal of the Movement Disorder Society, 2011, Feb-15, Volume: 26, Issue:3 Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Male; Middle Aged; Parkinson Disease; Thiamine	2011
Coenzyme Q10, hyperhomocysteinemia and MTHFR C677T polymorphism in levodopa-treated Parkinson's disease patients. Neuromolecular medicine, 2012, Volume: 14, Issue:1 Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Ubiquinone; Vitamin B 12	2012
Levodopa, vitamins, ageing and the neuropathy of Parkinson's disease. Journal of neurology, 2013, Volume: 260, Issue:11 Topics: Adult; Aged; Aging; Antiparkinson Agents; Cross-Sectional Studies; Female; Folic Acid; Humans; Levodopa; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Vitamin B 12	2013
Motor fluctuations and Helicobacter pylori in Parkinson's disease. Journal of neurology, 2013, Volume: 260, Issue:12 Topics: Aged; Antiparkinson Agents; Breath Tests; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Humans; Intestinal Absorption; Levodopa; Male; Parkinson Disease; Treatment Outcome; Vitamin B 12	2013
Prevalence and features of peripheral neuropathy in Parkinson's disease patients under different therapeutic regimens. Parkinsonism & related disorders, 2014, Volume: 20, Issue:1 Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Electromyography; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Peripheral Nervous System Diseases; Prevalence; Vitamin B 12	2014
First report on hemoglobin electrostatic immobilization on WO3 nanoparticles: application in the simultaneous determination of levodopa, uric acid, and folic acid. Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:14 Topics: Animals; Biosensing Techniques; Cattle; Folic Acid; Hemoglobins; Isoelectric Point; Levodopa; Metal Nanoparticles; Oxides; Static Electricity; Tungsten; Uric Acid	2016
[Chronic inflammatory demyelinating polyradiculoneuropathy associated with treatment using intraduodenal infusion of levodopa-carbidopa]. Revista de neurologia, 2019, 10-01, Volume: 69, Issue:7 Topics: Antiparkinson Agents; Carbidopa; Diagnosis, Differential; Dopamine; Drug Combinations; Duodenum; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Metabolic Networks and Pathways; Methionine; Middle Aged; Parkinson Disease; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2019
Engineering the liposomal formulations from natural peanut phospholipids for pH and temperature sensitive release of folic acid, levodopa and camptothecin. Materials science & engineering. C, Materials for biological applications, 2021, Volume: 123 Topics: Arachis; Camptothecin; Folic Acid; Humans; Hydrogen-Ion Concentration; Levodopa; Liposomes; Phospholipids; Temperature	2021