Page last updated: 2024-08-17

levodopa and fluorodopa f 18

levodopa has been researched along with fluorodopa f 18 in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (7.84)	18.7374
1990's	20 (39.22)	18.2507
2000's	18 (35.29)	29.6817
2010's	9 (17.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Calne, DB; Fahn, S; Heiman, GA; Nygaard, TG; Snow, BJ; Takahashi, H	1
Argentini, M; Cogoli-Greuter, M; Mäder, T; Weinreich, R; Wiese, C; Winterhalter, KH	1
Brooks, DJ; Findley, LJ; Ibanez, V; Marsden, CD; Playford, ED; Sawle, GV; Thompson, PD	1
Cogoli-Greuter, M; Weinreich, R; Wiese, C; Winterhalter, KH	1
Barrio, JR; Luxen, A; Melega, WP; Nissenson, CH; Perlmutter, MM; Phelps, ME	1
Chirakal, R; Firnau, G; Garnett, ES	2
Chirakal, R; Firnau, G; Garnett, ES; Nahmias, C; Sood, S	1
Adam, MJ; Ammann, W; Bergstrom, M; Harrop, R; Laihinen, A; Martin, WR; Rogers, JG; Ruth, TJ; Sayre, CI; Stoessl, AJ	1
Gordin, A; Kaakkola, S; Männistö, PT	1
Brooks, DJ; Burn, DJ; Lammertsma, AA; Luthra, S; Morrish, PK; Osman, S; Sawle, GV; Snow, BJ	1
Defer, GL; Degos, JD; Malapert, D; Remy, P; Ricolfi, F; Samson, Y	1
Björklund, A; Brooks, D; Brundin, P; Frackowiak, R; Lindvall, O; Marsden, CD; Odin, P; Rothwell, JC; Sawle, G; Widner, H	1
Calne, DB; Nygaard, TG; Snow, BJ; Takahashi, H	2
Cedarbaum, JM; Evans, A; Gjedde, A; Guttman, M; Kuwabara, H; Léger, G; Reches, A	1
Bhatia, K; Brooks, DJ; Burn, DJ; Marsden, CD; Sawle, GV; Turjanski, N	1
Bhatt, MH; Calne, DB; Nakamura, K; Nomoto, M; Okada, A; Osame, M; Snow, BJ	1
Aquilonius, SM; Hartvig, PG; Långström, B; Tedroff, J	1
Akiguchi, I; Fukuyama, H; Hanakawa, T; Kato, M; Kimura, J; Shibasaki, H	1
Cabaret, M; Caparros-Lefebvre, D; Godefroy, O; Petit, H; Rémy, P; Samson, Y; Steinling, M	1
Brown, WD; DeJesus, OT; Holden, JE; Malischke, LM; Nickles, RJ; Oakes, TR; Roberts, AD; Schueller, MJ; Taylor, MD	1
Fasth, KJ; Hartvig, P; Långström, B; Tedroff, J; Torstenson, R	1
Aigner, TG; Doudet, D; Fernández-Ruiz, J	1
Imahori, Y; Kawano, H; Misawa, A; Sawada, T; Takeuchi, Y	1
Calne, DB; de la Fuente-Fernández, R; Kishore, A; Mak, EK; Pal, PK; Ruth, TJ; Schulzer, M; Snow, BJ; Stoessl, AJ; Vingerhoets, FJ	1
Brooks, DJ	2
Bergman, J; Eronen, E; Eskola, O; Niinivirta, M; Oikonen, V; Rinne, UK; Ruottinen, HM; Solin, O; Sonninen, P	1
Barrio, JR; Cheng, DW; Huang, SC; Namavari, M; Satyamurthy, N; Yee, RE	1
DeJesus, OT; Holden, JE; Nickles, RJ; Roberts, AD; Shelton, SE	1
Jennings, D; Marek, K; Seibyl, J	1
Bailey, DL; Brooks, DJ; Ito, K; Morrish, PK; Pavese, N; Rakshi, JS; Uema, T	1
Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ	1
Bergman, J; Eskola, O; Forsback, S; Grönroos, T; Haapalinna, A; Haaparanta, M; Marjamäki, P; Niemi, R; Rinne, J; Solin, O	1
DeJesus, OT; Doudet, DJ; Endres, CJ; Holden, JE; Nickles, JR; Uno, H	1
Bailey, DL; Brooks, DJ; Pavese, N; Remy, P; Whone, AL	1
Cumming, P; Danielsen, EH; Gjedde, A; Kumakura, Y; Reilhac, A	1
Adams, J; de la Fuente-Fernández, R; Schulzer, M; Sossi, V; Stoessl, J	1
Deleu, D; Hanssens, Y	1
Brown, L; Dickson, D; Farrer, M; Skipper, L; Solida, A; Vingerhoets, FJ; Wider, C; Wszolek, ZK	1
Cumming, P; Kumakura, Y	1
Bakay, RA; Deogaonkar, M; Lieu, CA; Subramanian, T	1
Endres, CJ; Hayashi, T; Iida, H; Kumakura, Y; Matsubara, K; Minato, K; Watabe, H	1
Brooks, DJ; Lewis, SJ; Pavese, N; Rivero-Bosch, M; Whone, AL	1
Bours, V; Caberg, JH; Dive, D; Garraux, G; Jamar, M; Moonen, G; Vanbellinghen, JF	1
Eskola, O; Jokinen, P; Joutsa, J; Kaasinen, V; Rinne, JO	1
Arbizu, J; Collantes, M; DiCaudo, C; Luquin, MR; Marcilla, I; Ordóñez, C; Peñuelas, I; Riverol, M	1
Bendlin, BB; Buyan-Dent, L; Christian, BT; DeJesus, OT; Gallagher, CL; Harding, SJ; Holden, JE; Li, CT; Nickles, RJ; Oh, J; Okonkwo, O; Palotti, M; Stone, CK	1
Harada, N; Kakiuchi, T; Kanazawa, M; Muramatsu, S; Ohba, H; Tsukada, H	1
Barclay, CL; Barua, NU; Blinder, S; Boca, M; Boiko, C; Broadfoot, J; Cronin, D; Dharia, S; Fibiger, HC; Gill, SS; Harrison, R; Howell, M; Irving, C; Johnson, D; Johnson, GA; Kinch, S; Lawrence, AD; Lewis, O; Longpre, L; Luz, M; Marshall, C; Mohr, E; Mooney, L; Pritchard, G; Schroers, C; Skinner, P; Sossi, V; Stoessl, AJ; Whone, AL; Woolley, M	1

Reviews

6 review(s) available for levodopa and fluorodopa f 18

Article	Year
General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase. General pharmacology, 1994, Volume: 25, Issue:5 Topics: Animals; Behavior, Animal; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Dihydroxyphenylalanine; Humans; Levodopa; Microdialysis; Nitriles; Nitrophenols; Pentanones; Tolcapone; Tomography, Emission-Computed	1994
Functional positron emission tomographic studies of striatal dopaminergic activity. Changes induced by drugs and nigrostriatal degeneration. Advances in neurology, 1996, Volume: 69 Topics: Animals; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Neostriatum; Nerve Degeneration; Substantia Nigra; Tomography, Emission-Computed	1996
PET studies and motor complications in Parkinson's disease. Trends in neurosciences, 2000, Volume: 23, Issue:10 Suppl Topics: Antiparkinson Agents; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dyskinesia, Drug-Induced; Fluorine Radioisotopes; Humans; Levodopa; Neural Pathways; Opioid Peptides; Parkinson Disease; Pulse Therapy, Drug; Putamen; Receptors, Opioid; Tomography, Emission-Computed	2000
Do dopamine agonists or levodopa modify Parkinson's disease progression? European journal of neurology, 2002, Volume: 9 Suppl 3 Topics: Animals; Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Dihydroxyphenylalanine; Disease Progression; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; Indoles; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Tropanes	2002
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease. Experimental neurology, 2003, Volume: 184 Suppl 1 Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2003
PET studies of cerebral levodopa metabolism: a review of clinical findings and modeling approaches. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2009, Volume: 15, Issue:6 Topics: Animals; Brain; Computer Simulation; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Humans; Levodopa; Parkinson Disease; Pharmacokinetics; Positron-Emission Tomography	2009

Trials

4 trial(s) available for levodopa and fluorodopa f 18

Article	Year
The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease. Neurology, 1994, Volume: 44, Issue:7 Topics: Aged; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Drug Synergism; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Tomography, Emission-Computed	1994
A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: an 18F-dopa PET study. Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:12 Topics: Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Disease Progression; Fluorine Radioisotopes; Follow-Up Studies; Humans; Indoles; Levodopa; Middle Aged; Parkinson Disease; Tomography, Emission-Computed	2002
A technique for standardized central analysis of 6-(18)F-fluoro-L-DOPA PET data from a multicenter study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:7 Topics: Algorithms; Antiparkinson Agents; Canada; Dihydroxyphenylalanine; Dopamine Agents; France; Germany; Humans; Image Interpretation, Computer-Assisted; Indoles; Levodopa; Parkinson Disease; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed; Treatment Outcome; United Kingdom	2004
Levodopa effect on [18F]fluorodopa influx to brain: normal volunteers and patients with Parkinson's disease. Acta neurologica Scandinavica, 2004, Volume: 110, Issue:3 Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Blood-Brain Barrier; Body Fluid Compartments; Brain; Cerebellum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Drug Synergism; Female; Humans; Levodopa; Magnetic Resonance Imaging; Male; Metabolic Clearance Rate; Middle Aged; Parkinson Disease; Presynaptic Terminals; Putamen; Reference Values; Tomography, Emission-Computed	2004

Other Studies

41 other study(ies) available for levodopa and fluorodopa f 18

Article	Year
Long-term treatment response and fluorodopa positron emission tomographic scanning of parkinsonism in a family with dopa-responsive dystonia. Annals of neurology, 1992, Volume: 32, Issue:5 Topics: Adult; Aged; Brain; Child; Child, Preschool; Dihydroxyphenylalanine; Dystonia; Family; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pedigree; Tomography, Emission-Computed	1992
Metabolism of 5-fluoro-dopa and 6-fluoro-dopa enantiomers in aggregating cell cultures of fetal rat brain. Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Cells, Cultured; Dihydroxyphenylalanine; Female; Fetus; Levodopa; Rats; Rats, Inbred Strains; Stereoisomerism; Time Factors	1992
Isolated tremor and disruption of the nigrostriatal dopaminergic system: an 18F-dopa PET study. Neurology, 1992, Volume: 42, Issue:8 Topics: Adult; Aged; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Levodopa; Middle Aged; Parkinson Disease; Posture; Reference Values; Substantia Nigra; Tomography, Emission-Computed; Tremor	1992
Comparative metabolism of fluorinated 3,4-dihydroxyphenylalanine isomers in aggregating brain cell cultures. Journal of neurochemistry, 1992, Volume: 58, Issue:1 Topics: Animals; Brain; Cell Aggregation; Cells, Cultured; Decarboxylation; Dihydroxyphenylalanine; Levodopa; Methylation; Stereoisomerism	1992
Comparative in vivo metabolism of 6-[18F]fluoro-L-dopa and [3H]L-dopa in rats. Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12 Topics: Animals; Brain; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorine Radioisotopes; Injections, Intravenous; Kinetics; Levodopa; Male; Rats; Rats, Inbred Strains; Tritium	1990
High yield synthesis of 6-[18F]fluoro-L-dopa. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1986, Volume: 27, Issue:3 Topics: Arsenic; Arsenicals; Boranes; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorides; Fluorine; Isomerism; Isotope Labeling; Levodopa; Radioisotopes; Silanes; Silicon Compounds; Solvents	1986
Cerebral metabolism of 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine in the primate. Journal of neurochemistry, 1987, Volume: 48, Issue:4 Topics: Animals; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Frontal Lobe; Kinetics; Levodopa; Macaca mulatta; Male; Occipital Lobe	1987
Positron emission tomography in Parkinson's disease: glucose and DOPA metabolism. Advances in neurology, 1987, Volume: 45 Topics: Adult; Aged; Blood Glucose; Brain; Caudate Nucleus; Cerebellum; Deoxyglucose; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Humans; Levodopa; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed	1987
Aromatic radiofluorination with [18F]fluorine gas: 6-[18F]fluoro-L-dopa. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1984, Volume: 25, Issue:11 Topics: Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorine; Isotope Labeling; Levodopa; Magnetic Resonance Spectroscopy; Radioisotopes	1984
Rest tremor and extrapyramidal symptoms after midbrain haemorrhage: clinical and 18F-dopa PET evaluation. Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:8 Topics: Adult; Basal Ganglia Diseases; Dihydroxyphenylalanine; Electromyography; Fluorine Radioisotopes; Humans; Intracranial Arteriovenous Malformations; Levodopa; Male; Mesencephalon; Posture; Rest; Rupture, Spontaneous; Subarachnoid Hemorrhage; Thalamus; Tomography, Emission-Computed; Tremor	1994
Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease. Annals of neurology, 1994, Volume: 35, Issue:2 Topics: Brain Tissue Transplantation; Dihydroxyphenylalanine; Dopamine; Fetal Tissue Transplantation; Humans; Levodopa; Mesencephalon; Parkinson Disease; Putamen	1994
Positron emission tomographic studies of dopa-responsive dystonia and early-onset idiopathic parkinsonism. Annals of neurology, 1993, Volume: 34, Issue:5 Topics: Adolescent; Adult; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prognosis; Tomography, Emission-Computed	1993
Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa. Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:3 Topics: Animals; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Nitriles; Parkinson Disease; Tomography, Emission-Computed	1993
Comparison of striatal 18F-dopa uptake in adult-onset dystonia-parkinsonism, Parkinson's disease, and dopa-responsive dystonia. Neurology, 1993, Volume: 43, Issue:8 Topics: Adult; Age Factors; Caudate Nucleus; Dihydroxyphenylalanine; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed	1993
Clinical heterogeneity of dopa-responsive dystonia: PET observations. Advances in neurology, 1993, Volume: 60 Topics: Adult; Aged; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Tomography, Emission-Computed	1993
PET scan study on the dopaminergic system in a Japanese patient with hereditary progressive dystonia (Segawa's disease). Case report. Advances in neurology, 1993, Volume: 60 Topics: Corpus Striatum; Dihydroxyphenylalanine; Dystonia; Female; Humans; Japan; Levodopa; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed	1993
[A case of familial juvenile dystonia-parkinsonism: 18F-6-fluorodopa and 18F-fluoro-2-deoxyglucose PET study]. Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:5 Topics: Adult; Age of Onset; Brain; Deoxyglucose; Dihydroxyphenylalanine; Dystonia; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Levodopa; Parkinson Disease; Tomography, Emission-Computed	1996
PET study and neuropsychological assessment of a long-lasting post-encephalitic parkinsonism. Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:4-5 Topics: Aged; Antiparkinson Agents; Brain; Dihydroxyphenylalanine; Encephalitis, Arbovirus; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Levodopa; Memory Disorders; Neuropsychological Tests; Obsessive-Compulsive Disorder; Parkinson Disease; Phobic Disorders; Tomography, Emission-Computed	1998
FluoroDOPA PET shows the nondopaminergic as well as dopaminergic destinations of levodopa. Neurology, 1999, Oct-12, Volume: 53, Issue:6 Topics: Aged; Brain; Dihydroxyphenylalanine; Dopamine; Female; Humans; Kinetics; Levodopa; Male; Middle Aged; Tomography, Emission-Computed	1999
A comparison of 11C-labeled L-DOPA and L-fluorodopa as positron emission tomography tracers for the presynaptic dopaminergic system. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:10 Topics: Animals; Antiparkinson Agents; Benzophenones; Carbon Radioisotopes; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Levodopa; Macaca mulatta; Nitrophenols; Presynaptic Terminals; Tolcapone; Tomography, Emission-Computed	1999
Spatial memory improvement by levodopa in parkinsonian MPTP-treated monkeys. Psychopharmacology, 1999, Volume: 147, Issue:1 Topics: Animals; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine Agents; Fluorine Radioisotopes; Levodopa; Macaca mulatta; Male; Memory; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Psychomotor Performance; Space Perception	1999
Putaminal necrosis presenting with hemidystonia. Pediatric neurology, 2000, Volume: 22, Issue:3 Topics: Antiparkinson Agents; Brain Diseases; Child; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Dystonia; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Levodopa; Magnetic Resonance Imaging; Necrosis; Putamen; Tomography, Emission-Computed; Treatment Outcome	2000
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:1 Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Motor Neurons; Movement Disorders; Parkinson Disease; Presynaptic Terminals; Substantia Nigra; Tomography, Emission-Computed	2000
Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging. Synapse (New York, N.Y.), 2001, Volume: 40, Issue:1 Topics: Aged; Antiparkinson Agents; Brain; Catechol O-Methyltransferase; Catechols; Dihydroxyphenylalanine; Female; Humans; Levodopa; Male; Middle Aged; Movement; Nitriles; Parkinson Disease; Time Factors; Tomography, Emission-Computed	2001
Blood-brain barrier and neuronal membrane transport of 6-[18F]fluoro-L-DOPA. Biochemical pharmacology, 2001, Nov-15, Volume: 62, Issue:10 Topics: Animals; Biological Transport; Blood-Brain Barrier; Cell Membrane; Dihydroxyphenylalanine; Fluorine Radioisotopes; Levodopa; Male; Models, Animal; Neurons; Rats; Rats, Sprague-Dawley	2001
Effect of tetrabenazine on the striatal uptake of exogenous L-DOPA in vivo: a PET study in young and aged rhesus monkeys. Synapse (New York, N.Y.), 2002, Jun-15, Volume: 44, Issue:4 Topics: Adrenergic Uptake Inhibitors; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopamine Agents; Image Processing, Computer-Assisted; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Neuropeptides; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2002
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease. Synapse (New York, N.Y.), 2004, Volume: 51, Issue:2 Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Central Nervous System Stimulants; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Immunohistochemistry; Levodopa; Male; Oxidopamine; Parkinson Disease; Propionates; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase	2004
Time profile of cerebral [18F]6-fluoro-L-DOPA metabolites in nonhuman primate: implications for the kinetics of therapeutic L-DOPA. Frontiers in bioscience : a journal and virtual library, 2004, Jan-01, Volume: 9 Topics: Animals; Dihydroxyphenylalanine; Dopamine Agents; Fluorine Radioisotopes; Levodopa; Macaca nemestrina; Models, Biological; Time Factors	2004
Age-related differences in levodopa dynamics in Parkinson's: implications for motor complications. Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 4 Topics: Adult; Age Factors; Age of Onset; Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed	2006
Long-term 24-hour duodenal infusion of levodopa: outcome and dose requirements. Neurology, 2006, May-23, Volume: 66, Issue:10 Topics: Animals; Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Duodenum; Humans; Indoles; Infusion Pumps; Levodopa; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome	2006
Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model. Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:19-20 Topics: Antiparkinson Agents; Arousal; Brain; Brain Mapping; Diagnostic Imaging; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Movement; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon	2006
Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss family. Parkinsonism & related disorders, 2008, Volume: 14, Issue:6 Topics: Adult; Aged; Antiparkinson Agents; Brain; Chromosome Disorders; Dihydroxyphenylalanine; DNA Mutational Analysis; Female; Genes, Dominant; Humans; Levodopa; Male; Middle Aged; Mutation; Parkinson Disease; Pedigree; Phenotype; Positron-Emission Tomography; Radiopharmaceuticals	2008
Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys. Parkinsonism & related disorders, 2011, Volume: 17, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Carotid Arteries; Conditioning, Operant; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Dyskinesia, Drug-Induced; Dystonia; Female; Injections, Intravenous; Levodopa; Macaca mulatta; MPTP Poisoning; Parkinson Disease, Secondary; Psychomotor Performance; Radionuclide Imaging; Radiopharmaceuticals; Substantia Nigra	2011
Sensitivity of kinetic macro parameters to changes in dopamine synthesis, storage, and metabolism: a simulation study for [¹⁸F]FDOPA PET by a model with detailed dopamine pathway. Synapse (New York, N.Y.), 2011, Volume: 65, Issue:8 Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Levodopa; Linear Models; Macaca fascicularis; Models, Neurological; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity	2011
Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study. NeuroImage, 2011, Jun-01, Volume: 56, Issue:3 Topics: Amino Acid Transport Systems, Neutral; Antiparkinson Agents; Biogenic Monoamines; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Levodopa; Longitudinal Studies; Male; Middle Aged; Norepinephrine; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Serotonin	2011
Partial trisomy 4q associated with young-onset dopa-responsive parkinsonism. Archives of neurology, 2012, Volume: 69, Issue:3 Topics: Adult; Age of Onset; alpha-Synuclein; Antiparkinson Agents; Chromosomes, Human, Pair 4; Dihydroxyphenylalanine; Dopamine Agonists; Female; Gene Duplication; Humans; Intellectual Disability; Karyotyping; Levodopa; Magnetic Resonance Imaging; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Trisomy	2012
Seasonality of striatal dopamine synthesis capacity in Parkinson's disease. Neuroscience letters, 2012, Nov-14, Volume: 530, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Seasons	2012
Levodopa induces long-lasting modification in the functional activity of the nigrostriatal pathway. Neurobiology of disease, 2014, Volume: 62 Topics: Animals; Antiparkinson Agents; Aromatic-L-Amino-Acid Decarboxylases; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Neural Pathways; Parkinsonian Disorders; Positron-Emission Tomography; Substantia Nigra	2014
A dual-tracer study of extrastriatal 6-[18F]fluoro-m-tyrosine and 6-[18F]-fluoro-L-dopa uptake in Parkinson's disease. Synapse (New York, N.Y.), 2014, Volume: 68, Issue:8 Topics: Brain; Dihydroxyphenylalanine; Disease Progression; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Time Factors; Tyrosine	2014
Evaluation of 6-11C-Methyl-m-Tyrosine as a PET Probe for Presynaptic Dopaminergic Activity: A Comparison PET Study with β-11C-l-DOPA and 18F-FDOPA in Parkinson Disease Monkeys. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:2 Topics: Animals; Brain; Carbidopa; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Enzyme Inhibitors; Levodopa; Macaca fascicularis; MPTP Poisoning; Parkinson Disease, Secondary; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Presynaptic; Tyrosine	2016
Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson's Disease. Journal of Parkinson's disease, 2019, Volume: 9, Issue:2 Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Glial Cell Line-Derived Neurotrophic Factor; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Randomized Controlled Trials as Topic	2019