Compounds > levodopa

Page last updated: 2024-08-17

levodopa and dextromethorphan

levodopa has been researched along with dextromethorphan in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (42.86)	18.2507
2000's	4 (28.57)	29.6817
2010's	4 (28.57)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Kaur, S; Starr, MS	1
Blin, O; Fabre, N; Montastruc, JL; Rascol, O; Senard, JM	1
Chase, TN; Del Dotto, P; Natté, R; van den Munckhof, P; Verhagen Metman, L	1
Blanchet, PJ; Chase, TN; Del Dotto, P; van den Munckhof, P; Verhagen Metman, L	1
Lalonde, R; Lestienne, F; Thullier, F	1
Bonastre, M; Jiménez, A; Marin, C; Tolosa, E	1
Bonastre, M; Chase, TN; Jimenez, A; Marin, C; Tolosa, E	1
Martin, CM	1
Berger, SP; Brudney, EG; Johnson, SW; Meshul, CK; Paquette, MA; Putterman, DB	1
Berger, SP; Giuffrida, A; Johnson, SW; Macheda, T; Martinez, AA; Meshul, CK; Paquette, MA	1
Brodsky, M; Factor, SA; Fox, SH; Knowles, N; Lang, AE; Metman, LV; Nutt, JG; Pope, LE; Siffert, J	1
Blumberger, DM; Chen, R; Daskalakis, ZJ; Pollock, BG; Rajji, TK; Salavati, B; Zomorrodi, R	1

Trials

3 trial(s) available for levodopa and dextromethorphan

Article	Year
Dextromethorphan improves levodopa-induced dyskinesias in Parkinson's disease. Neurology, 1998, Volume: 51, Issue:1 Topics: Aged; Antiparkinson Agents; Antitussive Agents; Dextromethorphan; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, N-Methyl-D-Aspartate	1998
Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:6 Topics: Aged; Antiparkinson Agents; Cross-Over Studies; Dextromethorphan; Double-Blind Method; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Humans; Levodopa; Male; Middle Aged; Outcome Assessment, Health Care; Parkinson Disease; Pilot Projects; Quinidine	2017
Pharmacological Manipulation of Cortical Inhibition in the Dorsolateral Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:2 Topics: Adult; Baclofen; Cholinesterase Inhibitors; Cross-Over Studies; Dextromethorphan; Dopamine Agents; Double-Blind Method; Electroencephalography; Excitatory Amino Acid Antagonists; Female; GABA-B Receptor Agonists; Humans; Levodopa; Male; Neural Inhibition; Prefrontal Cortex; Rivastigmine; Transcranial Magnetic Stimulation; Young Adult	2018

Other Studies

11 other study(ies) available for levodopa and dextromethorphan

Article	Year
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Antiparkinsonian action of dextromethorphan in the reserpine-treated mouse. European journal of pharmacology, 1995, Jul-04, Volume: 280, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Behavior, Animal; Dextromethorphan; Dopamine Agonists; Drug Interactions; Levodopa; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; Parkinson Disease, Secondary; Phenethylamines; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine	1995
N-methyl-D-aspartate (NMDA) antagonist and Parkinson's disease: a pilot study with dextromethorphan. Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:2 Topics: Aged; Dextromethorphan; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; N-Methylaspartate; Neurologic Examination; Parkinson Disease; Receptors, N-Methyl-D-Aspartate	1994
Blockade of glutamatergic transmission as treatment for dyskinesias and motor fluctuations in Parkinson's disease. Amino acids, 1998, Volume: 14, Issue:1-3 Topics: Amantadine; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Levodopa; Movement Disorders; Parkinson Disease; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate	1998
Effects of dopaminergic agents and of an NMDA receptor antagonist on motor coordination in Lurcher mutant mice. Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Carbidopa; Dextromethorphan; Dopamine Agonists; Dopamine Antagonists; Female; Levodopa; Male; Mice; Mice, Neurologic Mutants; Olivopontocerebellar Atrophies; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate	1999
Narrow beneficial effect of dextromethorphan on levodopa-induced motor response alterations in an experimental model of parkinsonism. Brain research, 1999, Aug-21, Volume: 839, Issue:1 Topics: Animals; Antiparkinson Agents; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Treatment Outcome	1999
Non-NMDA receptor-mediated mechanisms are involved in levodopa-induced motor response alterations in Parkinsonian rats. Synapse (New York, N.Y.), 2000, Jun-15, Volume: 36, Issue:4 Topics: Animals; Antiparkinson Agents; Dextromethorphan; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Parkinsonian Disorders; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Riluzole; Rotation	2000
It's nothing to laugh about: understanding disorders of emotional expression. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2007, Volume: 22, Issue:9 Topics: Affective Symptoms; Antidepressive Agents; Crying; Dextromethorphan; Diagnosis, Differential; Dopamine Agents; Drug Combinations; Excitatory Amino Acid Antagonists; Expressed Emotion; Humans; Laughter; Levodopa; Quinidine; Treatment Outcome; Volition	2007
Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias. Neuroreport, 2008, Jan-08, Volume: 19, Issue:1 Topics: Adrenergic Agents; Amphetamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Dextromethorphan; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Ligands; Male; N-Methylaspartate; Neurotoxicity Syndromes; Oxidopamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors	2008
Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson's disease: role of NMDA vs. 5-HT1A receptors. The European journal of neuroscience, 2012, Volume: 36, Issue:9 Topics: Amantadine; Animals; Antiparkinson Agents; Cycloserine; Dextromethorphan; Dopamine Agents; Dyskinesias; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists	2012