levodopa has been researched along with cocaine in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (18.45) | 18.7374 |
| 1990's | 27 (26.21) | 18.2507 |
| 2000's | 37 (35.92) | 29.6817 |
| 2010's | 17 (16.50) | 24.3611 |
| 2020's | 3 (2.91) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Renshaw, DC | 1 |
| Creese, I; Iversen, SD | 1 |
| Heffner, TG; Stricker, EM; Zigmond, MJ | 2 |
| Cuparencu, B; Sandor, V | 1 |
| Moore, KE; Wuerthele, SM | 1 |
| Snyder, SH | 1 |
| Baweja, R; Patil, PN; Sokoloski, TD | 1 |
| Luchins, D | 1 |
| Heninger, GR; Kleber, HD; Kosten, TR; McDougle, CJ; Palumbo, JM; Price, LH | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB | 2 |
| Goshima, Y; Misu, Y; Nakamura, S; Ohno, K | 1 |
| Bergman, J; Madras, BK; Melia, KF; Spealman, RD | 1 |
| Barbanel, G; Kamenka, JM; Maurice, T; Vignon, J | 1 |
| Goshima, Y; Misu, Y; Nakamura, S | 1 |
| Duan, SM; Hori, T; Oomura, Y; Shimizu, N | 1 |
| Angrist, B; Wolfsohn, R | 1 |
| Kruk, ZL; Millar, J; Stamford, JA | 1 |
| Shannon, J; Tennant, F | 1 |
| Kantak, KM; Miczek, KA | 1 |
| Berman, ML; Tennant, F | 1 |
| Flemenbaum, A; Rosen, H; Slater, VL | 1 |
| Goshima, Y; Kubo, T; Misu, Y | 1 |
| Chapman, B; Feldman, JM | 1 |
| Muldoon, SM; Rorie, DK; Tyce, GM | 1 |
| Kashiwabara, K | 1 |
| al-Tikriti, MS; Baldwin, RM; Laruelle, M; Malison, RT; Neumeyer, JL; Sybirska, EH; Wisniewski, G; Zea-Ponce, Y; Zimmermann, RC; Zoghbi, SS | 1 |
| Laihinen, AO; Lehikoinen, PK; Någren, KA; Oikonen, VJ; Rinne, JO; Rinne, UK; Ruotsalainen, UH; Ruottinen, HM | 1 |
| Abi-Dargham, A; Baldwin, RM; Innis, RB; Laruelle, M; Scanley, BE; Seibyl, JP; Wallace, E; Wang, S; Zea-Ponce, Y; Zoghbi, S | 1 |
| Angrist, B; Sanfilipo, M; Wolfsohn, R | 1 |
| Nantwi, KD; Schoener, EP | 1 |
| Boja, JW; Ehlers, MD; Kim, SE; Kuhar, MJ; Scheffel, U; Steinert, C | 1 |
| Pinto-do-O, PC; Soares-da-Silva, P | 1 |
| Bonnet, JJ; Costentin, J; Thibaut, F; Vaugeois, JM | 1 |
| De Souza Silva, MA; Häcker, R; Huston, JP; Mattern, C; Nogueira, PJ; Schwarting, RK | 1 |
| Bunzow, JR; Chester, JA; Dziewczapolski, G; Falzone, TL; Fang, Y; Gershanik, O; Grandy, DK; Larson, JL; Low, MJ; McDougall, JA; Phillips, TJ; Pugsley, TA; Rubinstein, M; Saez, C; Zhang, G | 1 |
| Pothos, EN; Sulzer, D | 1 |
| Caronti, B; Margotta, V; Meco, G; Merante, A; Palladini, G; Ruggieri, S; Venturini, G | 1 |
| Serrão, MP; Soares-Da-Silva, P; Vieira-Coelho, MA | 1 |
| Jeon, BS; Jeong, JM; Lee, MC; Park, SS | 1 |
| Baumann, MH; Horowitz, JM; Kristal, MB; Torres, G | 1 |
| Fujita, M; Ito, Y; Kusuoka, H; Nishimura, T; Okada, T; Shimada, S; Tohyama, M; Watanabe, Y | 1 |
| Castronuovo, J; Feigin, A; Innis, RB; Marek, KL; Seibyl, JP; Sheff, K; Zoghbi, S | 1 |
| Ahlskog, JE; Burnett, OL; Maraganore, DM; Matsumoto, JY; O'Connor, MK; Stark, KF; Turk, MF; Uitti, RJ | 1 |
| Kim, DS; Palmiter, RD; Szczypka, MS | 1 |
| Stoessl, AJ; Van Kampen, JM | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H | 1 |
| McGeer, EG; Stoessl, AJ; Van Kampen, JM | 1 |
| Bergman, J; Eskola, O; Hinkka, SM; Nurmi, E; Rinne, JO; Solin, O; Sonninen, P | 1 |
| Guttman, M; Houle, S; Hussey, D; Kish, S; Stewart, D; Wilson, A | 1 |
| Andersson, M; Cenci, MA; Konradi, C | 1 |
| Mellgren, SI; Sjøholm, H; Sundsfjord, J | 1 |
| Hickey, MA; Morton, AJ; Reynolds, GP | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H | 1 |
| Chen, JC; Hwang, JJ; Liao, MH; Lin, KJ; Pan, WH; Ting, G; Wey, SP; Yen, TC | 1 |
| Froelick, GJ; Kim, DS; Palmiter, RD | 1 |
| Andersson, M; Cenci, MA; Westin, JE | 1 |
| KANIIKE, K; NAMBA, J; YOSHIDA, H | 1 |
| Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ | 1 |
| Hanger, D; Joyce, JN; Reploge, M; Yarkov, AV | 1 |
| Beckstead, MJ; Grandy, DK; Wickman, K; Williams, JT | 1 |
| Dohi, T; Hashimoto, W; Kitayama, S; Kumagai, K; Morioka, N; Morita, K | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Tsukada, H | 1 |
| Morgan, J; Sethi, KD | 1 |
| Bunney, BS; Shi, WX; Zhou, Y | 1 |
| Benkelfat, C; Casey, KF; Delaney, JS; Kolivakis, T; Leyton, M | 1 |
| Deleu, D; Hanssens, Y | 1 |
| Andren, PE; Svenningsson, P; Zhang, X | 1 |
| Linazasoro, G; Van Blercom, N | 1 |
| Bernardi, G; Federici, M; Geracitano, R; Mercuri, NB | 1 |
| Di Rocco, A; Nasser, S; Werner, P | 1 |
| Mark, GP; Painter, T; Roseberry, AG; Williams, JT | 1 |
| Andren, PE; Chergui, K; Svenningsson, P; Zhang, X | 1 |
| Gerfen, CR; Paletzki, R; Worley, P | 1 |
| Iida, A; Inoue, N; Kakiuchi, T; Kondo, Y; Muramatsu, S; Nakano, I; Nakayama, T; Okuno, T; Ono, F; Suzuki, Y; Takino, N; Terao, K; Tsukada, H | 1 |
| Calon, F; Di Paolo, T; Grégoire, L; Hornykiewicz, O; Rajput, A; Rajput, AH; Samadi, P | 1 |
| Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK | 1 |
| Di Paolo, T; Gilbert, F; Grégoire, L; Lévesque, D; Mahmoudi, S; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P | 1 |
| Bordia, T; Campos, C; McIntosh, JM; Quik, M | 1 |
| Green, CE; Lindsay, JA; Moeller, FG; Schmitz, JM; Stotts, AL | 1 |
| Bateup, HS; Birnbaum, S; Fisone, G; Greengard, P; Nestler, EJ; Santini, E; Shen, W; Surmeier, DJ; Valjent, E | 1 |
| Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G | 1 |
| Authier, N; Chassain, C; Denizot, H; Durif, F; Hafidi, A; Llorca, PM; Zengin-Toktas, Y | 1 |
| Crossman, AR; Kobylecki, C; Ravenscroft, P | 1 |
| Amalric, M; Beurrier, C; Chabbert, D; Concetta, L; Jaouen, F; Kerkerian-Le Goff, L; Langa, F; Marie, H; Melon, C; Révy, D; Salin, P; Tafi, E | 1 |
| Antinori, S; Devoto, P; Fattore, L; Fratta, W; Frau, R; Gessa, GL; Saba, P | 1 |
| Bordia, T; Drenan, RM; McGregor, M; McIntosh, JM; Quik, M | 1 |
| Atcherley, CW; Burrell, MH; Heien, ML; Lipski, J | 1 |
| Alvarsson, A; Kadkhodaei, B; Millan, MJ; Perlmann, T; Schintu, N; Stan, TL; Svenningsson, P; Zhang, X | 1 |
| Bedi, G; Bisaga, A; Foltin, RW; Nunes, EV; Shiffrin, L; Vadhan, NP | 1 |
| Bordia, T; Perez, XA; Quik, M; Zhang, D | 1 |
| Antinori, S; Devoto, P; Fattore, L; Fratta, W; Gessa, GL; Saba, P | 1 |
| Chen, Y; Lian, Y; Wang, C; Wang, R; Zhang, Y | 1 |
| Green, CE; Lane, SD; Moeller, FG; Schmitz, JM; Suchting, R; Vincent, J; Webber, HE | 1 |
| Algar, S; Ballesteros, JA; Benhamú, B; Brea, J; Cincilla, G; García-Cárceles, J; Ladron de Guevara-Miranda, D; López-Rodríguez, ML; Loza, MI; Roberts, RS; Rodríguez de Fonseca, F; Sánchez-Martínez, M; Sánchez-Merino, A; Teresa de Los Frailes, M; Vázquez-Villa, H | 1 |
| Han, XM; Li, YP; Liu, BP; Wang, RF; Wang, Z; Xu, SS; Zhang, HY | 1 |
2 review(s) available for levodopa and cocaine
| Article | Year |
|---|---|
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
On the effects of psychostimulants, antidepressants, and the antiparkinsonian drug levodopa on dopamine neurons.
Topics: Amphetamine; Animals; Antiparkinson Agents; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Neurons; Psychotropic Drugs; Rats | 2006 |
11 trial(s) available for levodopa and cocaine
| Article | Year |
|---|---|
A placebo-controlled trial of L-dopa/carbidopa in early cocaine abstinence.
Topics: Adult; Breath Tests; Carbidopa; Cocaine; Drug Combinations; Electrocardiography; Humans; Levodopa; Substance Withdrawal Syndrome | 1993 |
Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT.
Topics: Aged; Antiparkinson Agents; Biological Transport; Carbidopa; Cocaine; Corpus Striatum; Dopamine; Drug Therapy, Combination; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Monoamine Oxidase; Occipital Lobe; Parkinson Disease; Selegiline; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 1999 |
The effect of dopamine agonist therapy on dopamine transporter imaging in Parkinson's disease.
Topics: Aged; Brain; Brain Mapping; Carbidopa; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Motor Skills; Nerve Tissue Proteins; Parkinson Disease; Pergolide; Putamen; Tomography, Emission-Computed, Single-Photon | 1999 |
Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.
Topics: Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Dyskinesias; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Proportional Hazards Models; Quality of Life; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2000 |
Reproducibility and effect of levodopa on dopamine transporter function measurements: a [18F]CFT PET study.
Topics: Adult; Aged; Antiparkinson Agents; Biological Transport; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reproducibility of Results; Tomography, Emission-Computed | 2000 |
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Receptors, Dopamine; Thiazoles; Tomography, Emission-Computed | 2001 |
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2002 |
Levodopa and the progression of Parkinson's disease.
Topics: Aged; Cocaine; Corpus Striatum; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Presynaptic Terminals; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2005 |
Cocaine craving, euphoria, and self-administration: a preliminary study of the effect of catecholamine precursor depletion.
Topics: Adult; Catecholamines; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Diet, Protein-Restricted; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Humans; Levodopa; Male; Phenylalanine; Self Administration; Time Factors; Tyrosine | 2005 |
Contingency management and levodopa-carbidopa for cocaine treatment: a comparison of three behavioral targets.
Topics: Adult; Behavior Therapy; Carbidopa; Cocaine; Cocaine-Related Disorders; Dopamine Agents; Female; Humans; Levodopa; Male; Medication Adherence; Middle Aged; Proportional Hazards Models; Reinforcement, Psychology; Treatment Outcome | 2010 |
The effects of combination levodopa-ropinirole on cognitive improvement and treatment outcome in individuals with cocaine use disorder: A bayesian mediation analysis.
Topics: Adult; Bayes Theorem; Cocaine; Cognition; Double-Blind Method; Humans; Indoles; Levodopa; Mediation Analysis; Treatment Outcome | 2021 |
90 other study(ies) available for levodopa and cocaine
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Sex and drugs.
Topics: Amphetamine; Antidepressive Agents; Antihypertensive Agents; Aphrodisiacs; Cannabis; Cocaine; Cyproterone; Ethanol; Hallucinogens; Histamine H1 Antagonists; Hormones; Humans; Hypnotics and Sedatives; Levodopa; Lithium; Parasympatholytics; Sexual Behavior; Tranquilizing Agents | 1978 |
The pharmacological and anatomical substrates of the amphetamine response in the rat.
Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Cerebral Cortex; Cocaine; Dextroamphetamine; Drinking Behavior; Feeding Behavior; Humans; Hydroxydopamines; Levodopa; Locomotion; Male; Neural Pathways; Norepinephrine; Rats; Receptors, Adrenergic; Stereotyped Behavior; Stimulation, Chemical; Substantia Nigra; Tyrosine 3-Monooxygenase | 1975 |
Effects of dopaminergic agonists and antagonists of feeding in intact and 6-hydroxydopamine-treated rats.
Topics: Animals; Apomorphine; Benztropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; Cocaine; Dextroamphetamine; Dopamine; Dopamine Antagonists; Eating; Hydroxydopamines; Levodopa; Male; Methylphenidate; Methyltyrosines; Motor Activity; Rats; Spiperone; Telencephalon | 1977 |
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol | 1977 |
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan | 1977 |
Biochemical factors in Schizophrenia.
Topics: Amphetamines; Animals; Binding Sites; Brain; Cocaine; Dopamine; Humans; Levodopa; Parkinson Disease, Secondary; Psychoses, Substance-Induced; Receptors, Dopamine; Schizophrenia; Tranquilizing Agents | 1977 |
Competitive binding between cocaine and various drugs to synthetic levodopa melanin.
Topics: Binding, Competitive; Cocaine; In Vitro Techniques; Kinetics; Levodopa; Melanins; Protein Binding | 1977 |
The dopamine hypothesis of schizophrenia. A critical analysis.
Topics: Acetylcholine; Amphetamine; Apomorphine; Cocaine; Dopamine; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Levodopa; Methyldopa; Methyltyrosines; Models, Neurological; Psychoses, Substance-Induced; Schizophrenia; Tranquilizing Agents | 1975 |
Dopaminergic responsivity during cocaine abstinence: a pilot study.
Topics: Adult; Carbidopa; Cocaine; Dopamine Agents; Drug Combinations; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Prolactin; Receptors, Dopamine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Actions of levodopa on rat substantia nigra zona compacta neurons.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cocaine; Female; Levodopa; Male; Neurons; Nomifensine; Rats; Rats, Wistar; Substantia Nigra; Sulpiride | 1992 |
Picomolar concentrations of L-dopa stereoselectively potentiate activities of presynaptic beta-adrenoceptors to facilitate the release of endogenous noradrenaline from rat hypothalamic slices.
Topics: Animals; Cocaine; Electric Stimulation; Hydrazines; Hypothalamus; In Vitro Techniques; Isoproterenol; Levodopa; Male; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stereoisomerism | 1991 |
Discriminative stimulus effects of cocaine in squirrel monkeys: involvement of dopamine receptor subtypes.
Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Dopamine Agents; Dopamine Antagonists; Levodopa; Male; Oxazines; Receptors, Dopamine; Saimiri; Time Factors | 1991 |
Modulation by dopamine of [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP, a phencyclidine derivative) binding to the dopamine uptake complex.
Topics: alpha-Methyltyrosine; Animals; Benserazide; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Haloperidol; In Vitro Techniques; Levodopa; Male; Membrane Proteins; Methyltyrosines; Mice; Nerve Tissue Proteins; Phencyclidine; Piperazines; Rats; Reserpine | 1991 |
Dopamine uptake inhibition potentiates the effects of L-DOPA on rat substantia nigra zona compacta neurons.
Topics: Action Potentials; Amphetamine; Animals; Biological Transport; Cocaine; Dopamine; Dopamine Antagonists; Drug Synergism; Female; In Vitro Techniques; Levodopa; Male; Neurons; Neurotransmitter Uptake Inhibitors; Nomifensine; Rats; Rats, Inbred Strains; Substantia Nigra; Sulpiride | 1991 |
L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices.
Topics: Animals; Binding, Competitive; Carbidopa; Cocaine; Hydrazines; Hypothalamus; In Vitro Techniques; Levodopa; Norepinephrine; Propranolol; Rats; Structure-Activity Relationship; Sulpiride | 1991 |
Glutamate modulates dopamine release in the striatum as measured by brain microdialysis.
Topics: alpha-Methyltyrosine; Amino Acids; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dialysis; Dopamine; Glutamates; Levodopa; Methyltyrosines; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
A pilot trial of levodopa/carbidopa in early cocaine abstinence.
Topics: Adult; Arousal; Carbidopa; Cocaine; Drug Therapy, Combination; Humans; Levodopa; Pilot Projects; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |
Dissociation of the actions of uptake blockers upon dopamine overflow and uptake in the rat nucleus accumbens: in vivo voltammetric data.
Topics: Animals; Benztropine; Bupropion; Cocaine; Dopamine; Electric Stimulation; Electrochemistry; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Quantitative urine testing. A new tool for diagnosing and treating cocaine use.
Topics: Adolescent; Adult; Amantadine; Amino Acids; Cocaine; Female; Humans; Levodopa; Male; Radioimmunoassay; Substance-Related Disorders | 1989 |
Social, motor, and autonomic signs of morphine withdrawal: differential sensitivities to catecholaminergic drugs in mice.
Topics: Animals; Apomorphine; Autonomic Nervous System; Catecholamines; Clonidine; Cocaine; Dextroamphetamine; Levodopa; Mice; Mice, Inbred Strains; Morphine Dependence; Psychomotor Performance; Reaction Time; Social Behavior; Substance Withdrawal Syndrome | 1988 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1988 |
Clinical trial of carbidopa-L-dopa combination for cocaine abuse.
Topics: Carbidopa; Cocaine; Drug Therapy, Combination; Humans; Levodopa; Substance-Related Disorders | 1986 |
Biphasic actions of L-DOPA on the release of endogenous dopamine via presynaptic receptors in rat striatal slices.
Topics: Animals; Brocresine; Cocaine; Corpus Striatum; Dopamine; Drug Interactions; In Vitro Techniques; Levodopa; Male; Propranolol; Rats; Rats, Inbred Strains; Sulpiride | 1986 |
Mechanisms of catecholamine inactivation by the endocrine pancreas.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cells, Cultured; Cocaine; Cricetinae; Culture Media; Dopamine; Drug Synergism; Imipramine; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nortriptyline; Pargyline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Tranylcypromine | 1974 |
Effects of L-dopa and L-tyrosine on adrenergic transmission in the canine saphenous vein.
Topics: Animals; Blood Vessels; Calcium; Cocaine; Corticosterone; Dogs; Dopamine; In Vitro Techniques; Levodopa; Norepinephrine; Saphenous Vein; Sympathetic Nervous System; Synaptic Transmission; Tyrosine; Vasoconstriction | 1982 |
[A long-term qualitative behavioral change following chronic methamphetamine administration in Japanese monkeys (Macaca fuscata)].
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Levodopa; Macaca; Male; Methamphetamine | 1983 |
The effect of altered dopaminergic activity on food intake in the rat: evidence for an optimal level of dopaminergic activity for behavior.
Topics: Amphetamine; Amphetamines; Animals; Apomorphine; Brain; Cocaine; Dextroamphetamine; Dopamine; Feeding Behavior; Haloperidol; Levodopa; Methylphenidate; Rats; Spiperone | 1980 |
SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.
Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Chlorocebus aethiops; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Indans; Iodine Radioisotopes; Levodopa; Ligands; Maprotiline; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Papio; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 1993 |
PET studies on brain monoamine transporters with carbon-11-beta-CIT in Parkinson's disease.
Topics: Adult; Aged; Brain; Carbon Radioisotopes; Caudate Nucleus; Cerebellum; Cocaine; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Putamen; Serotonin; Thalamus; Tomography, Emission-Computed | 1995 |
Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.
Topics: Adult; Aged; Antiparkinson Agents; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reference Values; Tomography, Emission-Computed, Single-Photon | 1993 |
Cocaine and dopaminergic actions in rat neostriatum.
Topics: Animals; Benzazepines; Cocaine; Depression, Chemical; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Infusions, Intravenous; Levodopa; Male; Neostriatum; Neurons; Procaine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1993 |
Effect of dopaminergic drugs on the in vivo binding of [3H]WIN 35,428 to central dopamine transporters.
Topics: Amphetamine; Animals; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins | 1996 |
Studies on the pharmacology of the inward transport of L-DOPA in rat renal tubules.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Kidney; Levodopa; Male; Rats; Rats, Wistar | 1996 |
Pharmacological modifications of dopamine transmission do not influence the striatal in vivo binding of [3H]mazindol or [3H]cocaine in mice.
Topics: 4-Butyrolactone; Analysis of Variance; Animals; Cerebellum; Cocaine; Dextroamphetamine; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; GABA Modulators; Injections, Intravenous; Levodopa; Mazindol; Mice; Neostriatum; Protein Binding; Tritium | 1996 |
Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat.
Topics: Administration, Intranasal; Amphetamine; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Sodium Chloride | 1997 |
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Sequence; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Depressants; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Ethanol; Genotype; Humans; Levodopa; Locomotion; Maternal Behavior; Methamphetamine; Mice; Mice, Knockout; Molecular Sequence Data; Motor Activity; Mutagenesis, Site-Directed; Narcotics; Nucleus Accumbens; Receptors, Dopamine D2; Receptors, Dopamine D4; Sensitivity and Specificity; Substantia Nigra; Transcription, Genetic | 1997 |
Modulation of quantal dopamine release by psychostimulants.
Topics: Animals; Axons; Cells, Cultured; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Evoked Potentials; Levodopa; Nalidixic Acid; Naphthyridines; Neurons; PC12 Cells; Potassium; Quantum Theory; Rats; Spider Venoms; Tegmentum Mesencephali | 1998 |
Effects of cocaine treatment on the nervous system of planaria (Dugesia gonocephala s. l.). Histochemical and ultrastructural observations.
Topics: Animals; Catecholamines; Cocaine; Levodopa; Microscopy, Electron; Movement; Neurons; Physical Stimulation; Planarians; Reserpine; Synaptic Vesicles | 1997 |
Apical and basolateral uptake and intracellular fate of dopamine precursor L-dopa in LLC-PK1 cells.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Biological Transport; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Epithelial Cells; Kidney Tubules, Proximal; Kinetics; Levodopa; LLC-PK1 Cells; Piperazines; Swine | 1998 |
Dopa-responsive dystonia: a syndrome of selective nigrostriatal dopamine deficiency.
Topics: Adolescent; Adult; Age of Onset; Biopterins; Child; Cocaine; Corpus Striatum; DNA Mutational Analysis; Dopamine; Dopamine Agents; Dystonia; Female; GTP Cyclohydrolase; Humans; Iodine Radioisotopes; Levodopa; Male; Mutation; Neopterin; Pedigree; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 1998 |
Effects of cocaethylene on dopamine and serotonin synthesis in Long-Evans and Sprague-Dawley brains.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Levodopa; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin | 1998 |
Comparison between the decrease of dopamine transporter and that of L-DOPA uptake for detection of early to advanced stage of Parkinson's disease in animal models.
Topics: Animals; Biological Transport; Brain; Carrier Proteins; Cocaine; Disease Models, Animal; Dopa Decarboxylase; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease, Secondary; Radioligand Assay; Rats; Rats, Wistar; Rotation; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 1999 |
Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.
Topics: Animals; Autoradiography; Benzamides; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine beta-Hydroxylase; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Pyrrolidines; Receptors, Dopamine; Tyrosine 3-Monooxygenase | 2000 |
Effects of oligonucleotide antisense to dopamine D(1A) receptor messenger RNA in a rodent model of levodopa-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Cocaine; Denervation; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Gene Expression; Levodopa; Male; Oligonucleotides, Antisense; Oxidopamine; Phenotype; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Rotation; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Ketamine decreased striatal [(11)C]raclopride binding with no alterations in static dopamine concentrations in the striatal extracellular fluid in the monkey brain: multiparametric PET studies combined with microdialysis analysis.
Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Ketamine; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Osmolar Concentration; Raclopride; Tomography, Emission-Computed | 2000 |
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Apomorphine; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Cytoprotection; Dopamine Plasma Membrane Transport Proteins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Tissue Proteins; Oligonucleotides, Antisense; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tritium | 2000 |
cAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatum.
Topics: Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Denervation; DNA; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalins; Female; Gene Expression; Levodopa; Oligonucleotides, Antisense; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor AP-1 | 2001 |
Beta-CIT-SPECT combined with UPDRS appears to distinguish different parkinsonian conditions.
Topics: Aged; Antiparkinson Agents; Basal Ganglia; Cocaine; Diagnosis, Differential; Female; Humans; Levodopa; Linear Models; Male; Middle Aged; Motor Skills; Parkinsonian Disorders; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2002 |
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate | 2002 |
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys.
Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed | 2002 |
Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Cocaine; Dopamine Agents; Humans; Levodopa; Male; Methylphenidate; Mice; Mice, Inbred ICR; Organotechnetium Compounds; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Tropanes | 2002 |
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Immunohistochemistry; Levodopa; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Opioid, mu; Signal Transduction; Sodium Chloride | 2002 |
Time course of striatal DeltaFosB-like immunoreactivity and prodynorphin mRNA levels after discontinuation of chronic dopaminomimetic treatment.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Cocaine; Denervation; Dopamine; Dopamine Uptake Inhibitors; Enkephalins; Enzyme Inhibitors; Female; Hydroxydopamines; Immunohistochemistry; In Situ Hybridization; Levodopa; Neostriatum; Neural Pathways; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathectomy, Chemical | 2003 |
INHIBITIONS BY OUABAIN AND PROTOVERATRINE ON ACTIVE TRANSPORT OF L-DOPA INTO BRAIN SLICES.
Topics: Adenine Nucleotides; Animals; Biological Transport, Active; Calcium; Calcium, Dietary; Cerebral Cortex; Cocaine; Dihydroxyphenylalanine; Edetic Acid; Guinea Pigs; Ions; Levodopa; Magnesium; Metabolism; Ouabain; Potassium; Protoveratrines; Research; Sodium; Strophanthins; Veratrum; Veratrum Alkaloids | 1963 |
Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Benzopyrans; Carbidopa; Cocaine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Grooming; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Oxazines; Pyrroles; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Stereotyped Behavior | 2003 |
Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cocaine; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Antagonists; In Vitro Techniques; Iontophoresis; Levodopa; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Organophosphorus Compounds; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Dopamine D2; Receptors, Dopamine D3; Reserpine; Sodium Channel Blockers; Sulpiride; Tetrodotoxin | 2004 |
Transport of dopamine and levodopa and their interaction in COS-7 cells heterologously expressing monoamine neurotransmitter transporters and in monoaminergic cell lines PC12 and SK-N-SH.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; Carrier Proteins; Catecholamines; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Levodopa; PC12 Cells; Rats; Transfection | 2005 |
Acute NMDA receptor antagonism induces biphasic striatal utilization of L-[beta-11C]DOPA: PET studies in the conscious monkey brain.
Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Cocaine; Consciousness; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Levodopa; Macaca mulatta; Male; Neural Pathways; Positron-Emission Tomography; Presynaptic Terminals; Raclopride; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2005 |
Differential effects of cocaine on firing rate and pattern of dopamine neurons: role of alpha1 receptors and comparison with L-dopa and apomorphine.
Topics: Action Potentials; Animals; Apomorphine; Cocaine; Dopamine; Dopamine Agents; Levodopa; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Ventral Tegmental Area | 2006 |
Long-term 24-hour duodenal infusion of levodopa: outcome and dose requirements.
Topics: Animals; Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Duodenum; Humans; Indoles; Infusion Pumps; Levodopa; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome | 2006 |
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinson Disease; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subthalamic Nucleus; Tritium | 2006 |
Severe stuttering and motor tics responsive to cocaine.
Topics: Adult; Cocaine; Dopamine Agonists; Fluoxetine; Humans; Levodopa; Male; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Stuttering; Tics | 2007 |
Inhaled cocaine used to relieve "off" periods in patients with Parkinson disease and unpredictable motor fluctuations: a report of 2 cases.
Topics: Administration, Inhalation; Cocaine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Self Medication | 2006 |
Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice.
Topics: Animals; Cocaine; Colforsin; Cytoplasmic Vesicles; Dendrites; Dopamine; Dopamine Agonists; Inhibitory Postsynaptic Potentials; Leptin; Levodopa; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Obesity; Organ Culture Techniques; Receptors, Dopamine D2; Receptors, Leptin; Ventral Tegmental Area | 2007 |
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase | 2008 |
Differences between dorsal and ventral striatum in Drd1a dopamine receptor coupling of dopamine- and cAMP-regulated phosphoprotein-32 to activation of extracellular signal-regulated kinase.
Topics: Amphetamine; Animals; Basal Ganglia; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Green Fluorescent Proteins; Levodopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Receptors, Dopamine D1 | 2008 |
Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Embryonic Stem Cells; Levodopa; Macaca fascicularis; Methamphetamine; Movement Disorders; Neurons; Parkinson Disease; Positron-Emission Tomography; Putamen; Raclopride; Tyrosine 3-Monooxygenase | 2009 |
Metabotropic glutamate receptor II in the brains of Parkinsonian patients.
Topics: Aged; Aged, 80 and over; Amino Acids; Antiparkinson Agents; Brain; Cocaine; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Parkinsonian Disorders; Postmortem Changes; Radioligand Assay; Receptors, Metabotropic Glutamate; Tritium; Xanthenes | 2009 |
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides.
Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors | 2010 |
Nur77 mRNA levels and L-Dopa-induced dyskinesias in MPTP monkeys treated with docosahexaenoic acid.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Brain; Cocaine; Disease Models, Animal; Docosahexaenoic Acids; Drug Interactions; Dyskinesia, Drug-Induced; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; MPTP Poisoning; Nuclear Receptor Subfamily 4, Group A, Member 1; Protein Binding; RNA, Messenger; Statistics as Topic | 2009 |
Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.
Topics: Amphetamine; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Conotoxins; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereotyped Behavior | 2010 |
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors.
Topics: Animals; Catalepsy; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Fluorescent Antibody Technique; Green Fluorescent Proteins; Haloperidol; Immunohistochemistry; Levodopa; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Motor Activity; Neuronal Plasticity; Neurons; Synaptic Potentials | 2010 |
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists | 2012 |
Motivational properties of D2 and D3 dopamine receptors agonists and cocaine, but not with D1 dopamine receptors agonist and L-dopa, in bilateral 6-OHDA-lesioned rat.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Agonists; Dopaminergic Neurons; Levodopa; Male; Motivation; Motor Activity; Oxidopamine; Rats; Receptors, Dopamine; Rotarod Performance Test; Substantia Nigra; Tyrosine 3-Monooxygenase | 2013 |
Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia.
Topics: Adamantane; Alternative Splicing; Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Iodine Isotopes; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Sympatholytics | 2013 |
Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions.
Topics: Animals; Antiparkinson Agents; Anxiety; Cholinergic Neurons; Cocaine; Corpus Striatum; Diphtheria Toxin; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Heparin-binding EGF-like Growth Factor; Humans; Interneurons; Levodopa; Mice, Transgenic; Monosaccharide Transport Proteins; Movement; Neural Pathways; Neurotoxins; Promoter Regions, Genetic; Substantia Nigra | 2014 |
Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Imidazoles; Levodopa; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Self Administration; Thiones | 2016 |
Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Mice, Transgenic; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinsonian Disorders; Protein Binding; Receptors, Nicotinic | 2015 |
A novel electrochemical approach for prolonged measurement of absolute levels of extracellular dopamine in brain slices.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Amphetamine; Animals; Carbon; Carbon Fiber; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Electric Stimulation; Electrochemical Techniques; Extracellular Space; Levodopa; Microelectrodes; Pargyline; Rats, Wistar; Tissue Culture Techniques | 2015 |
Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, L-DOPA Responsivity, and Glutamatergic Neurotransmission.
Topics: Adrenergic Agents; Akathisia, Drug-Induced; Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligodeoxyribonucleotides, Antisense; Oxidopamine; Parkinsonian Disorders; Radiopharmaceuticals; Receptors, G-Protein-Coupled; Stereotyped Behavior; Synaptic Transmission; Time Factors; Tyrosine 3-Monooxygenase | 2015 |
Effects of levodopa-carbidopa-entacapone and smoked cocaine on facial affect recognition in cocaine smokers.
Topics: Adult; Carbidopa; Catechols; Cocaine; Cocaine-Related Disorders; Drug Interactions; Face; Female; Humans; Levodopa; Male; Middle Aged; Nitriles; Smoke; Young Adult | 2016 |
Striatal D1 medium spiny neuron activation induces dyskinesias in parkinsonian mice.
Topics: Animals; Antiparkinson Agents; Channelrhodopsins; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Female; Gene Expression Regulation; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxidopamine; Parkinsonian Disorders; Receptors, Dopamine D1; Sympatholytics | 2017 |
Levodopa prevents the reinstatement of cocaine self-administration in rats via potentiation of dopamine release in the medial prefrontal cortex.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Levodopa; Prefrontal Cortex; Rats; Self Administration | 2018 |
Hypnic Headache with Dopaminergic Neuron Dysfunction: New Insight from a Rare Case.
Topics: Benserazide; Brain; Cocaine; Dopamine Agents; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Drug Combinations; Fluorodeoxyglucose F18; Headache Disorders, Primary; Humans; Levodopa; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Putamen; Radiopharmaceuticals | 2019 |
2-(Fluoromethoxy)-4'-(
Topics: Animals; Biphenyl Compounds; Cocaine; Dopamine; Dopamine Agents; Dopamine Agonists; Humans; Indazoles; Levodopa; Ligands; Mice; Nitrofurans; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D1 | 2022 |
Sleep benefit in patients with Parkinson's disease is associated with the dopamine transporter expression in putamen.
Topics: Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Parkinson Disease; Putamen; Sleep; Tremor | 2023 |