Page last updated: 2024-08-17

levodopa and cimetidine

levodopa has been researched along with cimetidine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's9 (34.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Barbieri, C; Bierti, L; Caldara, R; Cambielli, M; Ferrari, C; Romussi, M1
Chamuleau, RA1
Reus, VI1
Barreca, T; Masturzo, P; Rolandi, E1
Alberetto, M; De Pasqua, A; Girardi, AM; Pellicciotta, G; Pontiroli, AE; Pozza, G1
Gangat, AE; Naidoo, LR; Simpson, MA1
Galmozzi, G; Marinoni, S; Zanoboni, A; Zanoboni-Muciaccia, W1
Carlson, HE; Chang, RJ1
D'Arcy, PF1
Gugler, R; Musch, E1
Frohman, LA; Gonzalez-Villapando, C; Szabo, M1

Reviews

2 review(s) available for levodopa and cimetidine

ArticleYear
Treatment of acute hepatic encephalopathy.
    The Netherlands journal of medicine, 1979, Volume: 22, Issue:6

    Topics: Acid-Base Imbalance; Acute Disease; Adrenal Cortex Hormones; Antacids; Anti-Bacterial Agents; Blood Coagulation Disorders; Bromocriptine; Cimetidine; Critical Care; Cross Circulation; Diuretics, Osmotic; Exchange Transfusion, Whole Blood; Extracorporeal Circulation; Gastrointestinal Hemorrhage; Hemoperfusion; Hepatic Encephalopathy; Hepatitis B Antibodies; Humans; Lactulose; Levodopa; Liver Circulation; Liver Transplantation; Neomycin; Parenteral Nutrition; Peritoneal Dialysis; Plasma; Renal Dialysis; Serum Albumin; Transplantation, Homologous

1979
Medication as a potential cause of depression.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Aug-16, Volume: 70, Issue:4

    Topics: Antihypertensive Agents; Antipsychotic Agents; Cardiovascular Agents; Cimetidine; Contraceptives, Oral; Depression; Humans; Levodopa; Steroids

1986

Trials

1 trial(s) available for levodopa and cimetidine

ArticleYear
Inhibition of cimetidine-induced hyperprolactinaemia by pretreatment with levodopa or bromocriptine.
    Clinical endocrinology, 1979, Volume: 10, Issue:1

    Topics: Adult; Bromocriptine; Cimetidine; Guanidines; Humans; Levodopa; Male; Middle Aged; Prolactin

1979

Other Studies

23 other study(ies) available for levodopa and cimetidine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Prolactin release by intravenous cimetidine in man: evidence for a suprapituitary locus on action.
    Clinical endocrinology, 1979, Volume: 11, Issue:6

    Topics: Adult; Cimetidine; Dopamine; Female; Guanidines; Histamine H2 Antagonists; Humans; Infusions, Parenteral; Levodopa; Male; Middle Aged; Prolactin; Sex Factors

1979
Behavioral side effects of medical drugs.
    Primary care, 1979, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Antihypertensive Agents; Antitubercular Agents; Aspirin; Behavior; Caffeine; Cimetidine; Contraceptives, Oral, Hormonal; Digitalis Glycosides; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Levodopa; Male; Mental Disorders; Parasympatholytics; Placebos; Propranolol; Psychoses, Substance-Induced; Reserpine; Sympathomimetics; Thyroid Hormones

1979
Cimetidine and L-dopa in the control of prolactin secretion in man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:3

    Topics: Cimetidine; Guanidines; Humans; Kinetics; Levodopa; Male; Prolactin

1979
Inhibitory effect of cimetidine on L-dopa-stimulated growth hormone release in normal man.
    Clinical endocrinology, 1984, Volume: 21, Issue:5

    Topics: Adult; Cimetidine; Depression, Chemical; Growth Hormone; Humans; Levodopa; Male; Prolactin; Secretory Rate

1984
Studies on the role of histamine in human pituitary function.
    Clinical endocrinology, 1980, Volume: 12, Issue:5

    Topics: Adult; Betazole; Cimetidine; Diphenhydramine; Female; Growth Hormone; Histamine; Humans; Levodopa; Male; Middle Aged; Pituitary Function Tests; Pituitary Gland; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine

1980
Early reports on drug interactions.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2

    Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine

1983
[Metabolic effects of antacids and interactions with other drugs].
    Zeitschrift fur Gastroenterologie, 1983, Volume: 21 Suppl

    Topics: Absorption; Alkalosis; Antacids; Cimetidine; Drug Interactions; Gastric Acid; Humans; Hypercalcemia; Levodopa

1983
Central nervous system-mediated stimulation of prolactin secretion by cimetidine, a histamine H2-receptor antagonist: impaired responsiveness in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: Adenoma; Adolescent; Adult; Animals; Carbidopa; Cimetidine; Female; Guanidines; Humans; Levodopa; Male; Metoclopramide; Pituitary Neoplasms; Postpartum Period; Pregnancy; Prolactin; Rats; Sex Factors

1980