Page last updated: 2024-08-17

levodopa and acetaminophen

levodopa has been researched along with acetaminophen in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.50)18.7374
1990's8 (25.00)18.2507
2000's9 (28.13)29.6817
2010's10 (31.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Fleming, JS; George, CF; Jones, S; Macklin, B; Renwick, AG; Robertson, DR; Waller, DG1
George, CF; Macklin, B; Renwick, AG; Roseveare, C; Waller, DG1
George, CF; Macklin, B; Renwick, AG; Usman, F; Waller, DG1
Sporer, KA1
George, CF; Higginson, I; Macklin, BS; Renwick, AG; Robertson, DR; Waller, DG1
Cross, N; Fleming, JS; George, CF; Macklin, BS; Renwick, AG; Robertson, DR; Waller, DG; Wood, ND1
Factor, SA; Hefti, F; Weiner, WJ1
Kalow, W1
Andrews, DJ; Lewin, DJ; Scott, PH1
D'Arcy, PF1
Bulling, M; Macklin, BS; O'Shea, N; Roberts, J; von Renwick, AG; Waller, DG1
Hatori, K; Kondo, T; Mizuno, Y1
García-Carmona, F; Valero, E; Varón, R1
Kamimura, N; Murayama, N; Sunagane, N; Terawaki, Y; Uruno, T; Yoshinobu, E1
Herkes, GK; McKay, D; Meagher, LJ; Needham, M1
Anne-Marie, W; Carine, JL; Henri, D; Isariebel, QP; Ulises-Javier, JH1
Asanuma, M; Kikkawa, Y; Kimoto, N; Miyazaki, I; Miyoshi, K; Murakami, S; Takeshima, M1
Aarons, L; Ogungbenro, K; Pertinez, H1
Esteban-Fernández de Ávila, B; Fang, RH; Karshalev, E; Litvan, I; Mundaca-Uribe, R; Nguyen, B; Wang, J; Wei, X; Zhang, L1

Reviews

1 review(s) available for levodopa and acetaminophen

ArticleYear
Ethnic differences in reactions to drugs and xenobiotics. Conjugation reactions.
    Progress in clinical and biological research, 1986, Volume: 214

    Topics: Acetaminophen; Amobarbital; Asian People; Canada; Catechol O-Methyltransferase; Ethnicity; Female; Ghana; Half-Life; Humans; Inactivation, Metabolic; Levodopa; London; Male; Metabolic Clearance Rate; New York; Parkinson Disease; Philippines; Scotland; White People

1986

Trials

6 trial(s) available for levodopa and acetaminophen

ArticleYear
The influence of levodopa on gastric emptying in healthy elderly volunteers.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Acetaminophen; Age Factors; Aged; Gastric Emptying; Humans; Levodopa; Male; Technetium Tc 99m Pentetate

1992
Gastric emptying in healthy volunteers after multiple doses of levodopa.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Acetaminophen; Administration, Oral; Adult; Double-Blind Method; Gastric Emptying; Half-Life; Humans; Levodopa; Male; Random Allocation

1991
Oral amino acids and gastric emptying: an investigation of the mechanism of levodopa-induced gastric stasis.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Acetaminophen; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Gastric Emptying; Glycine; Humans; Levodopa; Male; Tryptophan

1991
The influence of protein containing meals on the pharmacokinetics of levodopa in healthy volunteers.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:4

    Topics: Acetaminophen; Adult; Dietary Proteins; Gastric Emptying; Humans; Intestinal Absorption; Levodopa; Male; Parkinson Disease

1991
The effects of co-administration of benzhexol on the peripheral pharmacokinetics of oral levodopa in young volunteers.
    British journal of clinical pharmacology, 1996, Volume: 41, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiparkinson Agents; Chelating Agents; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Gastric Emptying; Humans; Levodopa; Male; Muscarinic Antagonists; Pentetic Acid; Trihexyphenidyl

1996
[Levodopa loading test as an early marker of Parkinson's disease].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:1

    Topics: Acetaminophen; Aged; Biomarkers; Gastric Emptying; Humans; Intestinal Absorption; Levodopa; Middle Aged; Parkinson Disease

1997

Other Studies

25 other study(ies) available for levodopa and acetaminophen

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Carbidopa-levodopa overdose.
    The American journal of emergency medicine, 1991, Volume: 9, Issue:1

    Topics: Acetaminophen; Carbidopa; Carisoprodol; Female; Humans; Hydrocodone; Ibuprofen; Levodopa; Middle Aged; Poisoning

1991
The influence of levodopa on gastric emptying in man.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:1

    Topics: Acetaminophen; Adult; Gastric Emptying; Half-Life; Humans; Levodopa; Male; Organotechnetium Compounds; Pentetic Acid; Technetium Tc 99m Pentetate

1990
Acetaminophen metabolism by cytochrome P450 monooxygenases in Parkinson's disease.
    Annals of neurology, 1989, Volume: 26, Issue:2

    Topics: Acetaminophen; Carbidopa; Cytochrome P-450 Enzyme System; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1989
Interference by levodopa and related compounds with paracetamol estimation.
    Lancet (London, England), 1982, May-22, Volume: 1, Issue:8282

    Topics: Acetaminophen; Drug Interactions; Female; Humans; Levodopa

1982
Early reports on drug interactions.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2

    Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine

1983
Tyrosinase-mediated oxidation of acetaminophen to 4-acetamido-o-benzoquinone.
    Biological chemistry, 2002, Volume: 383, Issue:12

    Topics: Acetaminophen; Agaricales; Analgesics, Non-Narcotic; Benzoquinones; Chromatography, High Pressure Liquid; Kinetics; Levodopa; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen Consumption; Polarography; Spectrophotometry, Ultraviolet

2002
[Simple method for precognition of drug interaction between oral iron and phenolic hydroxyl group-containing drugs].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:2

    Topics: Acetaminophen; Animals; Biological Availability; Biopharmaceutics; Citric Acid; Colorimetry; Droxidopa; Drug Interactions; Ferrous Compounds; Iron Compounds; Levodopa; Male; Mice; Mice, Inbred Strains; Suspensions

2005
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:8

    Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antiparkinson Agents; Antiviral Agents; Anxiety; Carbidopa; Ceftriaxone; Cervical Vertebrae; Depression; Dexamethasone; Diazepam; Doxepin; Electroconvulsive Therapy; Humans; Levodopa; Male; Middle Aged; Neuroleptic Malignant Syndrome; Oxycodone; Pain; Parkinson Disease; Selegiline; Spinal Injuries

2006
Sonolysis of levodopa and paracetamol in aqueous solutions.
    Ultrasonics sonochemistry, 2009, Volume: 16, Issue:5

    Topics: Acetaminophen; Free Radicals; Hydrogen Peroxide; Levodopa; Molecular Structure; Solutions; Ultrasonics

2009
Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity.
    Neurochemical research, 2012, Volume: 37, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dopamine Agents; Dopaminergic Neurons; Glutathione; Indomethacin; Levodopa; Meloxicam; Methyldopa; Mice; Neurons; Neuroprotective Agents; Quinones; Sympatholytics; Thiazines; Thiazoles

2012
Empirical and semi-mechanistic modelling of double-peaked pharmacokinetic profile phenomenon due to gastric emptying.
    The AAPS journal, 2015, Volume: 17, Issue:1

    Topics: Acetaminophen; Gastric Emptying; Humans; Levodopa; Models, Biological; Radionuclide Imaging; Time Factors

2015
A Microstirring Pill Enhances Bioavailability of Orally Administered Drugs.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:12

    Topics: Acetaminophen; Administration, Oral; Animals; Aspirin; Biological Availability; Drug Delivery Systems; Female; Levodopa; Magnesium; Male; Mice; Models, Animal; Nanoparticles; Swine

2021