levodopa has been researched along with 1-methyl-4-phenylpyridinium in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Marsden, CD | 1 |
| Jarvis, MF; Rubin, JG; Wagner, GC | 1 |
| Ichinose, H; Nagatsu, I; Nagatsu, T; Naoi, M; Takahashi, T | 1 |
| Lewin, R | 1 |
| de Yébenes, JG; Mena, MA; Pardo, B | 1 |
| Himori, N; Mishima, K | 1 |
| Iacovitti, L; Stull, ND | 1 |
| Olanow, CW | 1 |
| Bonnet, JJ; Cleren, C; Costentin, J; Dourmap, N; Vilpoux, C | 1 |
| Freed, WJ; Kishikawa, M; Takashima, H; Tsujihata, M | 1 |
| McGeer, EG; Stoessl, AJ; Van Kampen, JM | 1 |
| Burkhardt, K; Ludolph, AC; Schwarz, J; Storch, A | 1 |
| Engfer, A; Gille, G; Hung, ST; Janetzky, B; Moldzio, R; Ngyuen, A; Rausch, WD; Reichmann, H | 1 |
| Gille, G; Hundemer, HP; Hung, ST; Janetzky, B; Kolter, T; Moldzio, R; Rausch, WD; Reichmann, H | 1 |
| Dryhurst, G; Foster, SB; Han, J; Wrona, MZ | 1 |
| Gille, G; Radad, K; Rausch, WD; Reichmann, H | 1 |
| Acs, A; Farkas, A; Gyori, J; Szabó, H; Vehovszky, A | 1 |
| Chen, Y; Li, L; Tang, J; Yuan, L | 1 |
2 review(s) available for levodopa and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Adrenal Glands; Adult; Antiparkinson Agents; Brain Chemistry; Child; Child, Preschool; Cytoplasmic Granules; Dyskinesia, Drug-Induced; Environmental Pollutants; Fetus; Humans; Levodopa; Middle Aged; Palliative Care; Parkinson Disease; Prevalence; Research; Selegiline; Substantia Nigra; Time Factors | 1990 |
Deprenyl in the treatment of Parkinson's disease: clinical effects and speculations on mechanism of action.
Topics: 1-Methyl-4-phenylpyridinium; Antioxidants; Apoptosis; Clinical Trials as Topic; Dopamine; Double-Blind Method; Drug Therapy, Combination; Humans; Levodopa; Monoamine Oxidase Inhibitors; Multicenter Studies as Topic; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Parkinson Disease; Parkinson Disease, Secondary; Prospective Studies; Randomized Controlled Trials as Topic; Selegiline | 1996 |
1 trial(s) available for levodopa and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
Clinical trial for Parkinson's disease?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Levodopa; Models, Neurological; Monoamine Oxidase Inhibitors; Parkinson Disease; Parkinson Disease, Secondary; Prospective Studies; Pyridines; Pyridinium Compounds; Selegiline | 1985 |
15 other study(ies) available for levodopa and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
L-dopa reverses the effects of MPP+ toxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain Chemistry; Conditioning, Operant; Herbicides; Levodopa; Male; Mice; Psychomotor Performance; Pyridinium Compounds | 1986 |
Reduction of aromatic L-amino acid decarboxylase activity in clonal pheochromocytoma PC12h cells by culture in the presence of N-methyl-4-phenylpyridinium ion (MPP+).
Topics: 1-Methyl-4-phenylpyridinium; Animals; Aromatic-L-Amino-Acid Decarboxylases; Cell Count; Cell Line; Levodopa; Pheochromocytoma; Pyridinium Compounds; Rats; Serotonin; Tumor Cells, Cultured | 1988 |
L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Ascorbic Acid; Brain; Catecholamines; Electron Transport; Electron Transport Complex IV; Humans; Levodopa; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Rats; Tumor Cells, Cultured | 1995 |
The COMT inhibitor tolcapone potentiates the anticataleptic effect of Madopar in MPP(+)-lesioned mice.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Benserazide; Benzophenones; Catalepsy; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Drug Synergism; Haloperidol; Kinetics; Levodopa; Male; Mice; Mice, Inbred C57BL; Nitrophenols; Tolcapone; Tyrosine | 1994 |
Acidic fibroblast growth factor and catecholamines synergistically up-regulate tyrosine hydroxylase activity in developing and damaged dopamine neurons in culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Catecholamines; Cells, Cultured; Dopamine; Embryo, Mammalian; Fibroblast Growth Factor 1; gamma-Aminobutyric Acid; Kinetics; Levodopa; Mesencephalon; Neurons; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Rats; Serotonin; Tyrosine 3-Monooxygenase | 1996 |
Acute interactions between L-DOPA and the neurotoxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine in mice.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Biological Transport; Drug Interactions; Hypothalamus; Injections, Intraventricular; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 1999 |
Bromocriptine protects dopaminergic neurons from levodopa-induced toxicity by stimulating D(2)receptors.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Antisense Elements (Genetics); Autoreceptors; Bromocriptine; Cell Survival; Cells, Cultured; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Fetus; Fluoresceins; Free Radicals; Gene Expression; Levodopa; Mesencephalon; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sulpiride; Tyrosine 3-Monooxygenase | 1999 |
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Apomorphine; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Cytoprotection; Dopamine Plasma Membrane Transport Proteins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Tissue Proteins; Oligonucleotides, Antisense; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tritium | 2000 |
Protective effects of riluzole on dopamine neurons: involvement of oxidative stress and cellular energy metabolism.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Chlorides; Dopamine; Dose-Response Relationship, Drug; Energy Metabolism; Ferric Compounds; Humans; Levodopa; Lipid Peroxidation; Neuroglia; Neurons; Oxidative Stress; Oxidopamine; Rats; Riluzole | 2000 |
Protection of dopaminergic neurons in primary culture by lisuride.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Cells, Cultured; Cytoprotection; Dopamine; Levodopa; Lisuride; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Oxidative Stress | 2002 |
Pergolide protects dopaminergic neurons in primary culture under stress conditions.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Survival; Cells, Cultured; Dopamine; Dopamine Agents; Dopamine Agonists; Levodopa; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Pergolide; Stress, Physiological; Tyrosine 3-Monooxygenase | 2002 |
The parkinsonian neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)) mediates release of l-3,4-dihydroxyphenylalanine (l-DOPA) and inhibition of l-DOPA decarboxylase in the rat striatum: a microdialysis study.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Aromatic Amino Acid Decarboxylase Inhibitors; Body Temperature; Chromatography, High Pressure Liquid; Dopa Decarboxylase; Hydroxyindoleacetic Acid; Levodopa; Male; Mannitol; Microdialysis; Neostriatum; Parkinsonian Disorders; Perfusion; Rats; Rats, Sprague-Dawley; Salicylates; Serotonin; Time Factors | 2003 |
Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbidopa; Cell Count; Cells, Cultured; Dihydroergocryptine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Synergism; Female; Lactic Acid; Levodopa; Mice; Neuroglia; Neurons; Pregnancy; Sulpiride; Tyrosine 3-Monooxygenase | 2006 |
Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Artemia; Biological Assay; Biotransformation; Electron Transport Complex I; Glutathione Transferase; Herbicides; Inactivation, Metabolic; Levodopa; Rotenone | 2010 |
Evaluation of efficiency omega 3 fatty acid improves the behavioural phenotype and protects against oxidative stress against MPP+ induces Parkinson's disease in mice.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Behavior, Animal; Catalase; Fatty Acids, Omega-3; Freezing Reaction, Cataleptic; Frontal Lobe; Glutathione; Glutathione Peroxidase; Levodopa; Male; Mesencephalon; Mice; Open Field Test; Oxidative Stress; Parkinsonian Disorders; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2021 |