levallorphan and naloxone

levallorphan has been researched along with naloxone in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199073 (90.12)18.7374
1990's6 (7.41)18.2507
2000's1 (1.23)29.6817
2010's1 (1.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheney, BV1
Burkard, WP; Eggstein-Aeppli, L; Schmidhammer, H; Smith, CF1
Abel, MS; Dixon, JS; Epstein, JW; Fanshawe, WJ; McKenzie, TC; Meyerson, LR; Osterberg, AC; Regan, BA; Wennogle, LP1
Burgman, M; Grinnell, S; Haselton, N; Majumdar, S; Ocampo, J; Pasternak, AR; Pasternak, GW1
Langrehr, D1
Pasternak, GW; Snyder, SH; Wilson, HA1
Lattin, DL1
Grossman, W; Jurna, I1
Bird, SJ; Kuhar, MJ1
Simantov, R; Snyder, SH1
Wikler, A1
LaMotte, CC; Pert, CB; Snowman, A; Synder, SH1
Cervantes, P; Guyda, H; Lal, S; Nair, NP; Pulman, J1
Fennessy, MR; Laska, FJ1
Doenicke, A; Hug, P; Kugler, J; Spatz, R; Zimmermann, W1
Barritt, PW; Hawkes, RA; Jivani, SK1
Hatano, Y; Toda, N1
Doenicke, A; Hug, P; Kugler, J; Laub, M; Zimmermann, W1
Kuhar, MJ; Pasternak, GW; Simantov, R; Snyder, SH1
Lamotte, C; Pert, CB; Snyder, SH1
Chou, DT; Wang, SC1
Haigh, JC1
Crofford, MJ; Hui, FW; Smith, AA1
Bläsig, J; Herz, A; Höllt, V; Paschelke, G1
Aposhian, D; Goodman, R; Simantov, R; Snyder, SH1
Dahlstrom, J; Medzihradsky, F1
Holtzman, SG; O'Callaghan, JP1
Bläsig, J; Dum, J; Herz, A; Höllt, V; Schubert, P1
Buckett, WR; Shaw, JS1
Murayama, S; Okamoto, Y; Suzuki, T1
Picker, MJ; Yarbrough, J1
Yamada, Y1
Bueno, L; Fioramonti, J; Lopez, Y1
Belleau, B; Jolicoeur, FB; Lemaire, S; Ménard, D1
Bueno, L; Liberge, M; Murillo-Lopez, D; Rivière, PJ1
Dunlap, CE; Rose, JC; Valego, NK1
Inoki, R; Kudo, T; Ohkubo, T; Shibata, M; Takahashi, H1
Hedler, L; Schurr, C; Starke, K; Szabo, B1
Achterrath-Tuckermann, U; Jakovlev, V; Sofia, RD; Thiemer, K; von Schlichtegroll, A1
Kontani, H; Koshiura, R1
Colombo, M; La Regina, A; Petrillo, P; Sbacchi, M; Tavani, A1
Fujiwara, N; Masaoka, T; Namba, S; Namba, Y; Nishigaki, S; Wani, T1
Bianchetti, A; Guidice, A; Manara, L; Nava, F1
Hirose, Y; Kuroda, H; Ogawa, N; Tsukamoto, S1
Bueno, L; Fargeas, MJ; Fioramonti, J1
Gorodetzky, CW1
Pasternak, G; Pert, CB; Snyder, SH1
Pierson, AK1
Pasternak, GW; Pert, CB; Snyder, SH1
Inoki, R; Toyoda, T; Yamamoto, I1
Bläsig, J; Herz, A1
Evans, JM; Hogg, MI; Lunn, JN; Rosen, M2
Hayashi, G; Nurimoto, S; Suzuki, S; Takeda, M1
Crofford, M; Hui, F; Smith, AA1
Murano, T; Nishino, H; Yamamoto, H; Yano, I1
Duberstein, JL; Hegyi, T; Kaufman, DM1
Blatman, S1
Pert, CB; Snyder, SH1
Murphree, HB1
Hui, F; Smith, AA1
Holtzman, SG; Jewett, RE; Steinert, HR1
Dundee, JW; Gupta, PK; Jones, CJ1
Payne, JP1
Montel, H; Starke, K1
Holtzman, SG1
Hudson, HE; Kallos, T; Rouge, JC; Smith, TC1
Masuda, Y; Nishino, H; Yamamoto, H; Yano, I1
Bianchi, G; Fiocchi, R; Manara, L; Peracchia, F; Petrillo, P; Tavani, A1
Kream, RM; Stefano, GB; Zukin, RS1
Ohkawa, H1
Aziz, LA; Forsling, ML1
Bianchetti, A; Cattaneo, C; Dragonetti, M; Ferrarese, N; Giudice, A; Manara, L; Sacilotto, R1
Jurna, I; Rummel, W1
Gairola, RL; Gupta, PK; Pandley, K1
Kameyama, T; Nagasaka, M1
Akiyama, Y; Tagashira, E; Urano, T; Yanaura, S1
Korczyn, AD; Rock, M1
Olds, ME; Williams, KN1
Akers, RM; Barnes, MA; Johnson, DW; Pearson, RE1
Dondio, G; Giardina, G; Hay, DW; Kotzer, CJ; Petrillo, P; Underwood, DC1

Reviews

2 review(s) available for levallorphan and naloxone

ArticleYear
Assays for narcotic antagonist activity in rodents.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analgesics; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Heroin; Hot Temperature; Lens, Crystalline; Levallorphan; Meperidine; Mice; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxymorphone; Phenazocine; Pressure; Rabbits; Rats; Reaction Time; Reflex; Respiration; Tail

1973
Narcotic poisoning of children (1) through accidental ingestion of methadone and (2) in utero.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Administration, Oral; Apgar Score; Birth Weight; Child; Child Care; Female; Gestational Age; Heroin Dependence; Humans; Infant, Newborn; Levallorphan; Maternal-Fetal Exchange; Methadone; Nalorphine; Naloxone; Phenobarbital; Poisoning; Pregnancy; Substance Withdrawal Syndrome; Tablets

1974

Trials

3 trial(s) available for levallorphan and naloxone

ArticleYear
[The effect of naloxone and levallorphane following fentanyl on the blood gases, EEG and psychodiagnostic tests (author's transl)].
    Der Anaesthesist, 1978, Volume: 27, Issue:6

    Topics: Adult; Arrhythmias, Cardiac; Blood Gas Analysis; Double-Blind Method; Fentanyl; Humans; Levallorphan; Male; Naloxone; Psychological Tests; Respiration Disorders

1978
A comparative study of the narcotic against activity of naloxone and levallorphan.
    Anaesthesia, 1974, Volume: 29, Issue:6

    Topics: Blood Pressure; Carbon Dioxide; Depression, Chemical; Drug Synergism; Humans; Injections, Intravenous; Levallorphan; Male; Naloxone; Narcotic Antagonists; Narcotics; Pain; Placebos; Psychological Tests; Pupil; Reaction Time; Respiration

1974
Antagonists of morphine-induced respiratory depression. A study in postoperative patients.
    Anaesthesia, 1980, Volume: 35, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Doxapram; Humans; Levallorphan; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Random Allocation; Respiratory Insufficiency; Thiazoles; Time Factors

1980

Other Studies

76 other study(ies) available for levallorphan and naloxone

ArticleYear
Structure-activity relationships for drugs binding to the agonist and antagonist states of the primary morphine receptor.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Algorithms; Animals; Kinetics; Models, Molecular; Narcotic Antagonists; Narcotics; Protein Conformation; Rats; Receptors, Opioid; Structure-Activity Relationship

1988
Synthesis and biological evaluation of 14-alkoxymorphinans. 2. (-)-N-(cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one, a selective mu opioid receptor antagonist.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphinans; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, mu

1989
5-Aryl-3-azabicyclo[3.2.0]heptan-6-one ketals, compounds with morphine-like analgesic activity.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Analgesia; Analgesics; Animals; Biological Assay; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Gait; Indicators and Reagents; Morphine; Naloxone; Pain; Rats; Receptors, Opioid; Structure-Activity Relationship

1984
Generation of novel radiolabeled opiates through site-selective iodination.
    Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13

    Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Iodine Radioisotopes; Molecular Structure; Neurotransmitter Agents; Oxymorphone; Radioligand Assay; Receptors, Opioid

2011
[Antagonists of morphine-like analgesics].
    Der Anaesthesist, 1978, Volume: 27, Issue:6

    Topics: Analgesics, Opioid; Humans; Levallorphan; Nalorphine; Naloxone; Respiration Disorders

1978
Differentiation of opiate agonist and antagonist receptor binding by protein modifying reagents.
    Nature, 1975, Feb-06, Volume: 253, Issue:5491

    Topics: Animals; Binding Sites; Brain; Chloromercuribenzoates; Ethylmaleimide; Hydromorphone; In Vitro Techniques; Iodoacetates; Levallorphan; Levorphanol; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Receptors, Drug; Structure-Activity Relationship; Sulfhydryl Reagents; Tritium

1975
Treating narcotic overdose: Nalorphine, levallorphan, or naloxone?
    The Journal of the Arkansas Medical Society, 1976, Volume: 72, Issue:11

    Topics: Humans; Levallorphan; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Poisoning

1976
The effect of morphine on the activity evoked in ventrolateral tract axons of the cat spinal cord.
    Experimental brain research, 1976, Mar-15, Volume: 24, Issue:5

    Topics: Afferent Pathways; Animals; Axons; Brain Stem; Cold Temperature; Decerebrate State; Depression, Chemical; Evoked Potentials; Levallorphan; Medulla Oblongata; Morphine; Naloxone; Neural Conduction; Neural Inhibition; Reserpine; Spinal Cord; Synaptic Transmission

1976
Iontophoretic application of opiates to the locus coeruleus.
    Brain research, 1977, Feb-25, Volume: 122, Issue:3

    Topics: Acetylcholine; Animals; Brain Mapping; Cerebral Ventricles; Dextrorphan; Electrophysiology; Levallorphan; Levorphanol; Male; Morphine; Naloxone; Rats; Receptors, Opioid

1977
Opiate receptor binding in the pituitary gland.
    Brain research, 1977, Mar-18, Volume: 124, Issue:1

    Topics: Animals; Brain; Cattle; Diprenorphine; Levallorphan; Morphine; Naloxone; Pituitary Gland; Receptors, Opioid; Sodium; Temperature

1977
Methadone maintenance and narcotic blocking drugs.
    The International journal of the addictions, 1977, Volume: 12, Issue:7

    Topics: Aftercare; Cyclazocine; Extinction, Psychological; Heroin Dependence; Hospitalization; Humans; Levallorphan; Methadone; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Psychotherapy; Receptors, Opioid

1977
Opiate receptor binding in rhesus monkey brain: association with limbic structures.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: Animals; Haplorhini; Levallorphan; Limbic System; Macaca mulatta; Naloxone; Receptors, Opioid

1978
Effect of naloxone or levallorphan on serum prolactin concentrations and apomorphine-induced growth hormone secretion.
    Acta psychiatrica Scandinavica, 1979, Volume: 59, Issue:2

    Topics: Apomorphine; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Levallorphan; Male; Naloxone; Prolactin; Receptors, Dopamine; Schizophrenia

1979
Acute effects of opiate agonists, partial agonists and antagonists on brain monoamines in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 238, Issue:1

    Topics: Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cyclazocine; Dextrorphan; Female; Levallorphan; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Rats

1979
[The effect of the morphine antagonist naloxone on the effect of fentanyl].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:9

    Topics: Arousal; Electroencephalography; Fentanyl; Humans; Hypnotics and Sedatives; Levallorphan; Motor Activity; Naloxone; Time Factors; Wakefulness

1978
Maternal pethidine and neonatal depression.
    British medical journal, 1978, Jan-14, Volume: 1, Issue:6105

    Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levallorphan; Meperidine; Naloxone; Pregnancy

1978
Influence of fentanyl on the chronotropic response of isolated rabbit atria to cholinergic and adrenergic stimulation.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:1

    Topics: Acetylcholine; Animals; Electric Stimulation; Female; Fentanyl; Heart Rate; In Vitro Techniques; Levallorphan; Male; Morphine; Myocardial Contraction; Naloxone; Norepinephrine; Parasympathetic Nervous System; Rabbits; Sympathetic Nervous System

1978
The regional distribution of a morphine-like factors enkephalin in monkey brain.
    Brain research, 1976, Apr-16, Volume: 106, Issue:1

    Topics: Animals; Binding, Competitive; Brain; Brain Chemistry; Carboxypeptidases; Cerebellum; Cerebral Cortex; Corpus Striatum; Haplorhini; Leucyl Aminopeptidase; Levallorphan; Limbic System; Macaca mulatta; Medulla Oblongata; Membranes; Mesencephalon; Molecular Weight; Naloxone; Nerve Tissue Proteins; Oligopeptides; Rats; Receptors, Drug; Sodium Chloride; Spinal Cord; Thalamus

1976
Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section.
    Brain research, 1976, Aug-13, Volume: 112, Issue:2

    Topics: Animals; Haplorhini; Levallorphan; Macaca mulatta; Naloxone; Opium; Receptors, Drug; Spinal Cord

1976
Unit activity of amygdala and hippocampal neurons: effects of morphine and benzodiazepines.
    Brain research, 1977, May-13, Volume: 126, Issue:3

    Topics: Action Potentials; Amygdala; Animals; Atropine; Cats; Chlordiazepoxide; Depression, Chemical; Diazepam; Hippocampus; Levallorphan; Morphine; Naloxone; Neurons

1977
Fallow deer immobilisation with fentanyl and a neuroleptic.
    The Veterinary record, 1977, Apr-30, Volume: 100, Issue:18

    Topics: Animals; Azaperone; Deer; Female; Fentanyl; Immobilization; Injections, Intramuscular; Injections, Intravenous; Levallorphan; Male; Naloxone; Thiazines; Time Factors; Xylazine

1977
Inhibition of growth in young mice treated with d,1-methadone.
    European journal of pharmacology, 1977, Jun-15, Volume: 43, Issue:4

    Topics: Animals; Animals, Newborn; Appetite Depressants; Body Weight; Depression, Chemical; Drug Tolerance; Female; Growth; Levallorphan; Methadone; Methadyl Acetate; Mice; Nalorphine; Naloxone; Reaction Time; Stereoisomerism; Time Factors

1977
Comparison of withdrawal precipitating properties of various morphine antagonists and partial agonists in relation to their stereospecific binding to brain homogenates.
    Psychopharmacologia, 1976, Volume: 46, Issue:1

    Topics: Benzomorphans; Binding Sites; Brain; Humans; Levallorphan; Morphine Dependence; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Pentazocine; Receptors, Drug; Sodium; Stereoisomerism; Subcellular Fractions; Substance Withdrawal Syndrome

1976
Phylogenetic distribution of a morphine-like peptide 'enkephalin'.
    Brain research, 1976, Jul-23, Volume: 111, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Cell Membrane; Levallorphan; Manganese; Molecular Weight; Naloxone; Nerve Tissue Proteins; Oligopeptides; Phylogeny; Receptors, Drug; Sodium; Species Specificity; Stereoisomerism

1976
Concurrent determination of narcotic drugs in plasm by gas-liquid chromatography.
    Pharmacological research communications, 1975, Volume: 07, Issue:1

    Topics: Chromatography, Gas; Cocaine; Codeine; Cyclazocine; Humans; Levallorphan; Levorphanol; Methadone; Methods; Nalorphine; Naloxone; Narcotics; Pentazocine

1975
Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:3

    Topics: Analgesia; Analysis of Variance; Animals; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Hot Temperature; Humans; Levallorphan; Male; Methods; Morphine; Naloxone; Narcotic Antagonists; Pentazocine; Rats; Reaction Time; Substance Withdrawal Syndrome

1975
Comparison of in vivo and in vitro parameters of opiate receptor binding in naive and tolerant dependent rodents.
    Life sciences, 1975, Jun-15, Volume: 16, Issue:12

    Topics: Animals; Autoradiography; Brain; Cyclopropanes; Drug Tolerance; Etorphine; Humans; Levallorphan; Mice; Morphine; Naloxone; Opium; Pain; Rats; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
Dopaminergic drugs antagonize the psychotomimetic effects of partial-agonist analgesics.
    Psychopharmacologia, 1975, Jun-19, Volume: 42, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior; Benztropine; Cyclazocine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Levodopa; Male; Motor Activity; Naloxone; Piribedil; Rats; Rats, Inbred Strains; Stereotyped Behavior

1975
Effects of naloxone and levallorphan on the spinal cord reflex potentials under the spinal ischemic condition in cats.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:4

    Topics: Animals; Blood Pressure; Cats; Electric Stimulation; Female; Ischemia; Levallorphan; Male; Membrane Potentials; Naloxone; Reflex; Spinal Cord; Time Factors

1992
Cross-tolerance and enhanced sensitivity to the response rate-decreasing effects of opioids with varying degrees of efficacy at the mu receptor.
    Psychopharmacology, 1991, Volume: 105, Issue:4

    Topics: Animals; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Levallorphan; Nalorphine; Naloxone; Narcotics; Receptors, Opioid; Receptors, Opioid, mu

1991
[Role of substance P on neurogenic inflammation in the rat dental pulp and inferior lip].
    Fukuoka Shika Daigaku Gakkai zasshi, 1990, Volume: 17, Issue:2

    Topics: Animals; Capillary Permeability; Cheilitis; Dental Pulp; Evoked Potentials; Histamine Release; Levallorphan; Lip; Morphine; Naloxone; Pulpitis; Rats; Substance P

1990
Central and peripheral control of postprandial pyloric motility by endogenous opiates and cholecystokinin in dogs.
    Gastroenterology, 1991, Volume: 101, Issue:5

    Topics: Animals; Benzodiazepinones; Central Nervous System; Cholecystokinin; Dietary Fats; Dogs; Eating; Endorphins; Gastric Emptying; Levallorphan; Naloxone; Peripheral Nerves; Pylorus

1991
In vivo opioid activity of S-methyl and S-allyl morphinan derivatives.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Analgesics; Animals; Levallorphan; Levorphanol; Male; Morphinans; Naloxone; Pain Measurement; Rats; Receptors, Opioid; Structure-Activity Relationship

1990
Opposite central and peripheral control by endogenous opioids of intestinal motility in fed rats.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Administration, Oral; Animals; Captopril; Electromyography; Endorphins; Enkephalin, Methionine; Gastrointestinal Motility; Glycopeptides; Injections, Intraperitoneal; Injections, Intraventricular; Levallorphan; Male; Naloxone; Rats; Rats, Inbred Strains

1989
Comparison of high-dose opioid antagonist effects on ovine fetal cardiovascular function.
    Developmental pharmacology and therapeutics, 1989, Volume: 13, Issue:1

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Fetus; Gestational Age; Heart Rate; Levallorphan; Naloxone; Naltrexone; Sheep

1989
[Peripheral analgesic actions of opioid peptides and morphine analogues].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:2

    Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; Levallorphan; Lidocaine; Male; Mice; Morphine; Naloxone; Pain; Peptide Fragments

1986
Peripheral sympatho-inhibitory cardiovascular effects of opioid peptides in anaesthetized rabbits.
    British journal of pharmacology, 1988, Volume: 94, Issue:3

    Topics: Animals; Decerebrate State; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Hemodynamics; Levallorphan; Male; Naloxone; Norepinephrine; Pentobarbital; Quaternary Ammonium Compounds; Rabbits; Sympathetic Nervous System

1988
[The pharmacologic effect of flupirtine, a structurally new analgesic].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Drug Tolerance; Guinea Pigs; In Vitro Techniques; Kinetics; Lethal Dose 50; Levallorphan; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Reaction Time; Receptors, Opioid; Species Specificity

1985
The effects of morphine and morphine-related compounds on the rate of afferent discharges from the pulmonary receptors in bullfrog.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:3

    Topics: Animals; Apomorphine; Capsaicin; Dextromethorphan; In Vitro Techniques; Levallorphan; Lung; Morphine; Morphine Derivatives; Naloxone; Neurons, Afferent; Pentazocine; Rana catesbeiana; Receptors, Opioid

1985
Antagonism by N-methyl levallorphan-methane sulphonate (SR 58002 C) of morphine-elicited acute and chronic central and peripheral effects.
    Life sciences, 1988, Volume: 42, Issue:21

    Topics: Animals; Behavior, Animal; Brain; Buprenorphine; Gastrointestinal Motility; Intestine, Small; Levallorphan; Male; Morphine; Muscle, Smooth; Naloxone; Nociceptors; Rats

1988
Opiate-antagonist reversal of neurological deficits--experimental and clinical studies.
    The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:1

    Topics: Adult; Aged; Animals; Blood Flow Velocity; Brain Ischemia; Cats; Cerebrovascular Circulation; Chick Embryo; Disease Models, Animal; Dogs; Female; Humans; Injections, Intravenous; Levallorphan; Male; Middle Aged; Naloxone; Narcotic Antagonists; Nervous System Diseases; Tomography, X-Ray Computed

1986
Dissociation of morphine withdrawal diarrhea and jumping in mice by the peripherally selective opioid antagonist SR 58002 C.
    Life sciences, 1986, Dec-15, Volume: 39, Issue:24

    Topics: Animals; Body Weight; Diarrhea; Levallorphan; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome

1986
Survival effect of coenzyme Q10 and naloxone on experimental stroke gerbils.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: Animals; Cerebrovascular Disorders; Coenzymes; Electron Transport; Gerbillinae; Levallorphan; Naloxone; Time Factors; Ubiquinone

1986
Different targets for i.v. vs. i.c.v. administered morphine for its effect on colonic motility in dogs.
    European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1

    Topics: Animals; Colon; Dogs; Gastrointestinal Motility; Injections, Intravenous; Injections, Intraventricular; Levallorphan; Morphine; Naloxone; Narcotic Antagonists

1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
Opiate agonists and antagonists discriminated by receptor binding in brain.
    Science (New York, N.Y.), 1973, Dec-28, Volume: 182, Issue:4119

    Topics: Analgesics; Animals; Binding, Competitive; Brain; Hydromorphone; In Vitro Techniques; Levallorphan; Levorphanol; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxymorphone; Receptors, Drug; Sodium; Tritium

1973
The opiate receptor.
    Annals of internal medicine, 1974, Volume: 81, Issue:4

    Topics: Animals; Brain; Depression, Chemical; Haplorhini; Humans; Levallorphan; Monoamine Oxidase; Morphine Derivatives; Naloxone; Opium; Potassium; Protein Binding; Rats; Receptors, Drug; Sodium Chloride; Tritium

1974
Elaboration of a bradykinin-like substance in dog's canine pulp during electrical stimulation and its inhibition by narcotic and nonnarcotic analgesics.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:4

    Topics: Aminopyrine; Analgesics; Animals; Aspirin; Biological Assay; Bradykinin; Dental Pulp; Dogs; Electric Stimulation; Hypnotics and Sedatives; Levallorphan; Meperidine; Morphine; Nalorphine; Naloxone; Pentazocine

1973
[Problems in quantification of provoked morphine withdrawal in rats].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Animals; Behavior, Animal; Cyclazocine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Levallorphan; Morphine Dependence; Motor Activity; Naloxone; Rats; Substance Withdrawal Syndrome

1974
Homobenzomorphan compounds with a potent narcotic antagonist property.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:3

    Topics: Analgesics; Animals; Benzomorphans; Blood Pressure; Depression, Chemical; Lethal Dose 50; Levallorphan; Male; Mice; Mice, Inbred Strains; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Pentazocine; Rabbits; Reaction Time; Respiration

1974
Trophic functions of the neuron. VI. Other trophic systems. Inhibition of growth by methadone and other cholinolytic drugs.
    Annals of the New York Academy of Sciences, 1974, Mar-22, Volume: 228, Issue:0

    Topics: Ambystoma; Animals; Animals, Newborn; Cell Differentiation; Choline; Depression, Chemical; Female; Growth; Hemicholinium 3; Larva; Levallorphan; Levorphanol; Male; Methadone; Mice; Mice, Inbred Strains; Naloxone; Parasympatholytics; Regeneration; Taste Buds

1974
Studies on the physical dependence liability of analgesics. 1. Electron microscopic studies on the ultra-structural transformation of mitochondria in the cells of zona fasciculata of the adrenal cortex in morphine addicted rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Adrenal Glands; Animals; Cold Temperature; Dactinomycin; Formaldehyde; Humans; Levallorphan; Male; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Morphine Dependence; Naloxone; Pituitary Gland; Rats; Substance Withdrawal Syndrome

1973
Heroin intoxication in adolescents.
    Pediatrics, 1972, Volume: 50, Issue:5

    Topics: Adolescent; Atrial Fibrillation; Blood Gas Analysis; Blood Pressure; Female; Heroin; Humans; Hypoxia; Intubation, Intratracheal; Levallorphan; Male; Nalorphine; Naloxone; Pneumonia, Aspiration; Positive-Pressure Respiration; Pulmonary Edema; Pupil; Respiration; Substance-Related Disorders

1972
Opiate receptor: demonstration in nervous tissue.
    Science (New York, N.Y.), 1973, Mar-09, Volume: 179, Issue:4077

    Topics: Analgesics; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Codeine; Colchicine; Dextromethorphan; Dextropropoxyphene; Guinea Pigs; Histamine; Intestinal Mucosa; Levallorphan; Methadone; Mice; Morphine; Nalorphine; Naloxone; Phenazocine; Phenobarbital; Rats; Receptors, Drug; Serotonin; Tritium

1973
Opiate antagonists and 'blockers'.
    American family physician, 1973, Volume: 7, Issue:4

    Topics: Cyclazocine; Humans; Levallorphan; Methadone; Nalorphine; Naloxone; Narcotic Antagonists; Substance-Related Disorders

1973
Inhibition of neurotrophic activity in salamanders treated with opioids.
    Experimental neurology, 1973, Volume: 39, Issue:1

    Topics: Animals; Hindlimb; Levallorphan; Levorphanol; Methadone; Mitosis; Naloxone; Nerve Regeneration; Taste Buds; Urodela

1973
Naloxone and levallorphan: a comparative study of agonist activity.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Blood Pressure; Carbon Dioxide; Depression, Chemical; Humans; Levallorphan; Naloxone; Pupil; Respiration

1973
Some agonistic actions of the morphone antagonist levallorphan on behavior and brain monoamines in the rat.
    Psychopharmacologia, 1973, Jul-04, Volume: 31, Issue:1

    Topics: Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Levallorphan; Male; Motor Activity; Naloxone; Norepinephrine; Rats; Serotonin

1973
Modification of the analgesic action of pethidine and morphine by three opiate antagonists, a respiratory stimulant (doxapram) and an analeptic (nikethamide); a study using an experimental pain stimulus in man.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Analgesia; Doxapram; Drug Interactions; Female; Humans; Levallorphan; Male; Meperidine; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Nikethamide; Respiration

1973
Narcotic antagonists and their uses in obstetrics.
    British journal of anaesthesia, 1973, Volume: 45

    Topics: Drug Interactions; Female; Humans; Labor, Obstetric; Levallorphan; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Obstetrics; Pentazocine; Pregnancy

1973
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
    British journal of pharmacology, 1973, Volume: 49, Issue:4

    Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System

1973
Narcotic antagonists as stimulants of behavior in the rat: specific and nonspecific effects.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Conditioning, Operant; Cyclazocine; Dopamine; Dose-Response Relationship, Drug; Electroshock; Levallorphan; Male; Mice; Mice, Inbred Strains; Motor Activity; Naloxone; Narcotic Antagonists; Norepinephrine; Pentazocine; Rats; Stimulation, Chemical

1973
Interaction of the effects of naloxone and oxymorphone on human respiration.
    Anesthesiology, 1972, Volume: 36, Issue:3

    Topics: Adult; Analgesics; Carbon Dioxide; Drug Interactions; Female; Humans; Levallorphan; Male; Morphinans; Naloxone; Narcotic Antagonists; Oxygen; Oxymorphone; Partial Pressure; Preanesthetic Medication; Respiration; Ventilation-Perfusion Ratio

1972
[Dependence on central analgesics. 4. Electron microscopic studies of the changes of the zona fasciculata in the adrenal cortex of codeine addicted rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:6

    Topics: Adrenal Glands; Animals; Codeine; Humans; Levallorphan; Male; Microscopy, Electron; Mitochondria; Naloxone; Rats; Substance-Related Disorders

1971
The peripheral narcotic antagonist N-allyl levallorphan-bromide (CM 32191) selectively prevents morphine antipropulsive action and buprenorphine in-vivo binding in the rat intestine.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:5

    Topics: Animals; Binding, Competitive; Buprenorphine; Central Nervous System; Gastrointestinal Motility; Intestinal Mucosa; Intestines; Levallorphan; Male; Morphinans; Morphine; Naloxone; Narcotic Antagonists; Oxymorphone; Rats; Reaction Time

1984
Demonstration of stereospecific opiate binding in the nervous tissue of the marine mollusc Mytilus edulis.
    Brain research, 1980, Jan-13, Volume: 181, Issue:2

    Topics: Animals; Dextrorphan; Dopamine; Enkephalins; Ganglia; Levallorphan; Mollusca; Naloxone; Receptors, Opioid

1980
Effects of enkephalin and endorphin on the inhibitory junction potentials in the duodenal smooth muscle cells of the guinea-pig.
    The Japanese journal of physiology, 1984, Volume: 34, Issue:1

    Topics: Animals; beta-Endorphin; Duodenum; Endorphins; Enkephalin, Methionine; Female; Gastrointestinal Motility; Guinea Pigs; Levallorphan; Male; Membrane Potentials; Muscle, Smooth; Naloxone; Neural Inhibition; Neuromuscular Junction; Synaptic Transmission

1984
Release of vasopressin in response to hypoxia and the effect of aminergic and opioid antagonists.
    The Journal of endocrinology, 1983, Volume: 99, Issue:1

    Topics: Animals; Arginine Vasopressin; Blood Pressure; Guanethidine; Heart Rate; Hypoxia; Levallorphan; Male; Metoclopramide; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sympatholytics

1983
Levallorphan methyl iodide (SR 58002), a potent narcotic antagonist with peripheral selectivity superior to that of other quaternary compounds.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Animals; Constipation; Female; Gastrointestinal Motility; Levallorphan; Mice; Morphine; Naloxone; Structure-Activity Relationship

1983
Depression by morphine and levorphanol of activity in sympathetic nerve fibres in anaesthetized rats.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Adrenergic Fibers; Anesthesia; Animals; Blood Pressure; Dextrorphan; Heart Rate; Levallorphan; Levorphanol; Male; Morphine; Naloxone; Pentazocine; Rats; Rats, Inbred Strains

1984
The effects of analgesics on quickly-learned conditioned suppression in mice.
    Neuropharmacology, 1982, Volume: 21, Issue:12

    Topics: Aging; Analgesics; Animals; Conditioning, Psychological; Electroshock; Emotions; Levallorphan; Male; Mice; Motor Activity; Naloxone

1982
Studies of physical dependence on cinepazide in rats.
    The Journal of toxicological sciences, 1980, Volume: 5, Issue:2

    Topics: Animals; Barbiturates; Behavior, Animal; Body Weight; Central Nervous System Depressants; Dose-Response Relationship, Drug; Humans; Levallorphan; Morphine; Naloxone; Piperazines; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1980
Antagonism of opiate mydriasis in mice.
    British journal of pharmacology, 1981, Volume: 73, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Levallorphan; Male; Mice; Morphine; Mydriatics; Nalorphine; Naloxone; Pupil

1981
Self-administration of D-Ala2-Met-enkephalinamide at hypothalamic self-stimulation sites.
    Brain research, 1980, Jul-21, Volume: 194, Issue:1

    Topics: Animals; Dextrorphan; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Hypothalamus; Levallorphan; Levorphanol; Male; Morphine; Naloxone; Naltrexone; Rats; Self Stimulation

1980
A synthetic opioid peptide increases plasma growth hormone and prolactin in Holstein calves.
    Journal of animal science, 1993, Volume: 71, Issue:4

    Topics: Animals; Blood-Brain Barrier; Cattle; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Female; Growth Hormone; Injections, Intravenous; Least-Squares Analysis; Levallorphan; Naloxone; Narcotic Antagonists; Prolactin; Random Allocation

1993
The antitussive activity of delta-opioid receptor stimulation in guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Animals; Carbazoles; Cell Line; CHO Cells; Cloning, Organism; Codeine; Cough; Cricetinae; Dextromethorphan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Humans; Hydrocodone; Levallorphan; Male; Naloxone; Narcotic Antagonists; Protein Binding; Pyridines; Pyrroles; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2000