leupeptins and bicyclo(3.3.1)nonane

leupeptins has been researched along with bicyclo(3.3.1)nonane* in 1 studies

Other Studies

1 other study(ies) available for leupeptins and bicyclo(3.3.1)nonane

Article	Year
Discovery of bicyclo[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors. Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12 Bicyclo[3,3,1]non-2-ene was used as a novel three-dimensional skeleton for the design and synthesis of hypoxia-inducible factor (HIF)-1 inhibitors. Among the compounds synthesized, compound 4b was found to be a potent inhibitor of HIF-1α protein accumulation under hypoxia and inhibited HIF-1α transcriptional activity in HeLa (human cervical carcinoma) cells (half maximal inhibitory concentration [IC Topics: Bridged Bicyclo Compounds; Drug Design; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Proteasome Endopeptidase Complex; Transcription, Genetic	2018

Article

Year

Discovery of bicyclo[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors.

Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

Bicyclo[3,3,1]non-2-ene was used as a novel three-dimensional skeleton for the design and synthesis of hypoxia-inducible factor (HIF)-1 inhibitors. Among the compounds synthesized, compound 4b was found to be a potent inhibitor of HIF-1α protein accumulation under hypoxia and inhibited HIF-1α transcriptional activity in HeLa (human cervical carcinoma) cells (half maximal inhibitory concentration [IC

Topics: Bridged Bicyclo Compounds; Drug Design; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Proteasome Endopeptidase Complex; Transcription, Genetic

2018