leupeptin has been researched along with leucine in 91 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (28.57) | 18.7374 |
| 1990's | 37 (40.66) | 18.2507 |
| 2000's | 21 (23.08) | 29.6817 |
| 2010's | 6 (6.59) | 24.3611 |
| 2020's | 1 (1.10) | 2.80 |
| Authors | Studies |
|---|---|
| Isobe, N; Kaneko, H; Nakatsuka, I; Saito, K; Yamada, H; Yoshitake, A | 1 |
| Ashall, F; Djamgoz, MB; Floyd, DN | 1 |
| Ivy, GO | 1 |
| Hara, M; Inagaki, C; Omori, K; Otani, H; Zeng, XT | 1 |
| Fukushima, T; Sasaki, H; Sekizawa, K; Takishima, T; Yamauchi, K; Yamaya, M; Zayasu, K | 1 |
| Azuma, M; David, LL; Kadoya, K; Lampi, KJ; Shearer, TR | 1 |
| Kumar, A; Shafiq, S; Stracher, A; Wadgaonkar, R | 1 |
| Benacerraf, B; Colarusso, LJ; Falo, LD; Rock, KL | 1 |
| Bisiau, H; Degand, P; Demeyer, D; Han, KK; Huet, G; Richet, C; Soudan, B; Tetaert, D | 1 |
| Aoyagi, T; Hayashi, H; Hori, M; Moriya, Y; Nagai, M; Otani, T; Sakata, N; Tsuchiya, KS | 1 |
| Choudhuri, S; Klaassen, CD; McKim, JM | 1 |
| Knops, J; Lieberburg, I; Sinha, S | 1 |
| Jani, JP; Lazo, JS; Mistry, JS; Morris, G; Sebti, SM | 1 |
| Chiyotani, A; Isono, K; Kanemura, T; Konno, K; Sakai, N; Takizawa, T; Tamaoki, J; Yamauchi, F | 1 |
| Chiyotani, A; Horii, S; Isono, K; Kanemura, T; Kobayashi, K; Sakai, N; Takeuchi, S; Takizawa, T; Tamaoki, J; Yamawaki, I | 1 |
| Knutson, VP | 1 |
| Hayashi, M; Inomata, M; Ito, H; Kawashima, S; Saito, Y | 1 |
| Olaya, P; Wasserman, M | 1 |
| Mercer, JR; Silva, SV | 1 |
| Nishimura, C; Nishimura, T; Suzuki, H; Tanaka, N | 1 |
| Lasek, RJ; Sahenk, Z | 1 |
| Ivy, GO; Kanai, S; Kitani, K; Nokubo, M; Ohta, M; Otsubo, K; Sato, Y | 1 |
| Ishida, E; Ito, M; Sato, A; Shigeta, S; Takami, Y; Tanabe, F | 1 |
| Berlet, HH; Ilzenhöfer, H | 1 |
| Kurita, Y; Nakao, H; Ogawa, H; Takamori, K; Tsuboi, R | 2 |
| Kosaki, G; Suzuki, K; Tanoue, K; Yamamoto, K; Yamazaki, H | 1 |
| Ballard, FJ; Chandler, CS | 1 |
| Aikawa, M; Leech, JH; McKerrow, JH; Nagasawa, H; Rosenthal, PJ | 1 |
| Ito, M; Katunuma, N; Kominami, E; Kuroda, Y; Miyao, M; Naito, E; Takeda, E; Toshima, K | 1 |
| Ahsan, A; Bain, DL; Ostrowski, LE; Pagast, P; Patel, A; Schultz, RM; Suthar, BP; Wong, C | 1 |
| Iizuka, H; Iwasaki, Y; Konno, H; Yamamoto, H; Yamamoto, T | 1 |
| Hibino, T; Sato, K; Yokozeki, H | 1 |
| Hoppe, W; Kresse, H; Rauch, U | 1 |
| Iizuka, H; Iwasaki, Y; Kadoya, S; Yamamoto, T | 1 |
| Kato, H; Naito, H; Noguchi, T; Takahashi, A; Takahashi, S | 1 |
| Dresden, MH; Xu, YZ | 1 |
| Ishiura, S; Kamakura, K; Sano, M; Sugita, H | 1 |
| Banerjee, A; Burg, J; Sandhoff, K | 1 |
| Beertsen, W; Everts, V; Tigchelaar-Gutter, W | 1 |
| Andersen, KB | 1 |
| Hirano, T; Miyazaki, T; Yamada, H | 1 |
| Aoyagi, T; Harada, S; Kojima, F; Nagai, M; Ohuchi, S; Umezawa, H; Wada, T | 1 |
| Freeman, SJ; Lloyd, JB | 1 |
| Amenta, JS; Mayer, RJ; Russell, SM | 1 |
| Horii, I; Koyama, J; Nomura, J; Suzuki, Y | 1 |
| Drazen, JM; Lilly, CM; Martins, MA | 1 |
| Cho, SY; Chung, YB; Joo, IJ; Kang, SY; Kong, Y | 1 |
| Atsma, DE; Bastiaanse, EM; Jerzewski, A; Van der Laarse, A; Van der Valk, LJ | 1 |
| Rosenthal, PJ | 1 |
| Coombs, GH; North, MJ; Scott, DA | 1 |
| Claeys, E; Demeyer, D; Uytterhaegen, L | 1 |
| Kishore, BK; Maldague, P; Montenez, JP; Tulkens, PM | 1 |
| Cyr, DG; Guest, I; Varma, DR | 1 |
| Homma, Y; Ikeuchi, Y; Kim, K; Suzuki, A | 1 |
| Schnellmann, RG; Yang, X | 1 |
| Cummings, NJ; Groves, MR; Jenkins, JA; Pickersgill, RW; Scott, M; Taylor, MA | 1 |
| Kim, IS; Kim, YB; Lee, KJ | 1 |
| Hasselgren, PO; Luo, GJ; Wang, JJ; Wang, L | 1 |
| Baker, SC; Kanjanahaluethai, A; Lai, MM; Oh, JW; Schiller, JJ; Shi, ST | 1 |
| Hunter-Ensor, M; Naidoo, N; Sehgal, A; Song, W | 1 |
| Atkinson, HJ; Brain, P; Glen, DM; Shewry, PR; Urwin, PE; Walker, AJ | 1 |
| Knap, AK; Peppard, JV | 1 |
| Barbato, C; Calissano, P; Canu, N; Ciotti, MT; Dus, L; Serafino, A | 1 |
| Fagard, R; Lijnen, P; Petrov, V | 1 |
| Cooper, BS; Garrett, WM; Guthrie, HD | 1 |
| Hayashi, Y; Inoue, H; Kizu, Y; Mizuno, F; Ono, M; Saito, I; Takada, K; Tsubota, K; Yamada, K; Yanagi, K | 1 |
| Justesen, J; Martensen, PM | 1 |
| Gauthier, P; Grenier, D; Mayrand, D; Nakayama, K; Plamondon, P | 1 |
| Rosenthal, PJ; Semenov, AV; Shenai, BR | 1 |
| Kim, JH; Mullin, CA | 1 |
| Ikeda, T | 1 |
| Beis, I; Gaitanaki, C; Papazafiri, P | 1 |
| Campbell, RL; Cuerrier, D; Davies, PL; Moldoveanu, T | 1 |
| Fujisaki, K; Islam, KM; Kamio, T; Miyoshi, T; Tsuji, N | 1 |
| Ebihara, T; Hattori, S; Irie, S; Matsubara, Y; Miura-Yokota, Y | 1 |
| Alviano, CS; Branquinha, MH; d'Avila-Levy, CM; Dias, FA; Elias, CG; Lopes, AH; Pereira, FM; Ribeiro, RO; Santos, AL; Soares, RM; Souto-Padrón, T | 1 |
| Alcaide-Hidalgo, JM; de Boer, AR; Irth, H; Kolkman, J; Krabbe, JG; Lingeman, H; Niessen, WM; van Emde Boas, CN | 1 |
| Hiroi, Y; Ohshita, T | 1 |
| Alhassan, A; Govind, Y; Igarashi, I; Okubo, K; Yokoyama, N | 1 |
| Ahn, SJ; Chung, JK; Hong, YK; Jang, JH; Jeon, SJ; Kim, KH; Kim, MS; Kim, NY; Lee, HH; Seo, JS | 1 |
| Branquinha, MH; d'Avila-Levy, CM; Dias, FA; Elias, CG; Lopes, AH; Pereira, FM; Santos, AL; Silva, TL | 1 |
| Kim, YS; Kwon, HJ; Lee, HK | 1 |
| Craig, MJ; Pienta, KJ; Roca, H; Sud, S; Varsos, ZS; Ying, C | 1 |
| Hu, Y; Itoh, Y; Morioka, K | 1 |
| Hayakawa, T; Kawase, N; Kishi, J; Nakamura, H | 1 |
| Maemoto, Y; Maki, M; Osako, Y; Shibata, H; Suzuki, H; Tanaka, R | 1 |
| Bai, B; Jäämaa, S; Laiho, M; Latonen, L; Moore, HM | 1 |
| Ahmad, H; Alam, SM; Chou, YW; Kumar, S; Lin, MF; Muniyan, S; Zhang, L | 1 |
| Campbell, RL; Davies, PL; McCartney, CE; Ye, Q | 1 |
| Arafa, FM; Elkerdany, ED; Elnassery, SM; Mady, RF; Zaki, SA | 1 |
91 other study(ies) available for leupeptin and leucine
| Article | Year |
|---|---|
Differences in alpha 2u-globulins increased in male rat kidneys following treatment with several alpha 2u-globulin accumulating agents: cystein protease(s) play(s) an important role in production of kidney-type-alpha 2u-globulin.
Topics: Alpha-Globulins; Animals; Chlorobenzenes; Cyclohexanones; Cyclohexenes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Kidney; Leucine; Leupeptins; Limonene; Male; Naphthalenes; Octanes; Rats; Rats, Sprague-Dawley; Terpenes | 1992 |
Protease activities in carp retina.
Topics: Amino Acid Sequence; Animals; Carps; Coumarins; Endopeptidases; Hydrogen-Ion Concentration; Leucine; Leupeptins; Molecular Sequence Data; Peptides; Phenanthrolines; Protease Inhibitors; Retina; Serine Endopeptidases; Tosyllysine Chloromethyl Ketone | 1992 |
Protease inhibition causes some manifestations of aging and Alzheimer's disease in rodent and primate brain.
Topics: Aging; Alzheimer Disease; Animals; Brain; Dolichols; Endopeptidases; Humans; Immunologic Techniques; Intermediate Filaments; Leucine; Leupeptins; Lipofuscin; Macaca fascicularis; Male; Protease Inhibitors; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Ubiquitins | 1992 |
Different patterns of protein kinase C redistribution mediated by alpha 1-adrenoceptor stimulation and phorbol ester in rat isolated left ventricular papillary muscle.
Topics: Adrenergic alpha-Agonists; Animals; Leucine; Leupeptins; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Protease Inhibitors; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1992 |
Opsonized zymosan decreases cytoplasmic motility of alveolar macrophages in dogs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aminopeptidases; Animals; Calcium; Captopril; Cells, Cultured; Cytoplasm; Dogs; Indomethacin; Leucine; Leupeptins; Macrophages; Phagocytosis; Pulmonary Alveoli; Superoxide Dismutase; Zymosan | 1992 |
Comparison of cell-permeable calpain inhibitors and E64 in reduction of cataract in cultured rat lenses.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calpain; Cataract; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Culture Techniques; Cysteine Proteinase Inhibitors; Dipeptides; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Lens, Crystalline; Leucine; Leupeptins; Molecular Sequence Data; Rats; Rats, Sprague-Dawley | 1992 |
The effect of protease inhibitors, leupeptin and E64d, on differentiation of C2C12 myoblasts in tissue culture.
Topics: Animals; Calcium; Calpain; Cell Differentiation; Cell Fusion; Culture Techniques; Leucine; Leupeptins; Mice; Muscles; Protease Inhibitors | 1992 |
Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules.
Topics: Animals; Antigen-Presenting Cells; Cells, Cultured; Cyanogen Bromide; Endopeptidases; In Vitro Techniques; Leucine; Leupeptins; Mice; Molecular Weight; Ovalbumin; Peptides | 1992 |
Characterization of different proteolytic activities in Trypanosoma brucei brucei.
Topics: Amino Acid Sequence; Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dithiothreitol; Endopeptidases; Glycoproteins; Hydrogen-Ion Concentration; Kinetics; Leucine; Leupeptins; Molecular Sequence Data; Protease Inhibitors; Trypanosoma brucei brucei | 1992 |
Aminopeptidase activity of an antitumor antibiotic, C-1027.
Topics: Aminoglycosides; Aminopeptidases; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoproteins; Carcinoma, Ehrlich Tumor; Cell Survival; DNA, Neoplasm; Enediynes; Leucine; Leupeptins; Microsomes; Oligopeptides; Peptides; Proteins; Substrate Specificity; Swine; Tumor Cells, Cultured; Ultraviolet Rays | 1992 |
Role of hepatic lysosomes in the degradation of metallothionein.
Topics: Animals; Cathepsins; Electrophoresis, Polyacrylamide Gel; Leucine; Leupeptins; Liver; Lysosomes; Male; Metallothionein; Pepstatins; Rats; Rats, Inbred Strains | 1992 |
Evidence for a nonsecretory, acidic degradation pathway for amyloid precursor protein in 293 cells. Identification of a novel, 22-kDa, beta-peptide-containing intermediate.
Topics: Amyloid beta-Protein Precursor; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Humans; Kinetics; Leucine; Leupeptins; Molecular Weight; Peptide Fragments; Transfection | 1992 |
Cysteine proteinase inhibitors and bleomycin-sensitive and -resistant cells.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cysteine Proteinase Inhibitors; Drug Resistance; Drug Synergism; Head and Neck Neoplasms; Leucine; Leupeptins; Tumor Cells, Cultured | 1991 |
Effect of neutral endopeptidase inhibition on substance-P-induced increase in short-circuit current of canine cultured tracheal epithelium.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport, Active; Captopril; Cells, Cultured; Complement C1; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Female; Furosemide; Glycopeptides; In Vitro Techniques; Ion Channel Gating; Leucine; Leupeptins; Male; Membrane Potentials; Neprilysin; Substance P; Time Factors; Trachea | 1991 |
Atrial natriuretic factor inhibits ciliary motility in cultured rabbit tracheal epithelium.
Topics: Animals; Atrial Natriuretic Factor; Captopril; Cells, Cultured; Cilia; Enzyme Inhibitors; Epithelium; Glycopeptides; Indomethacin; Kinetics; Leucine; Leupeptins; Male; Masoprocol; Methylene Blue; Movement; Piroxicam; Purinones; Rabbits; Thiorphan; Trachea | 1991 |
Proteolytic processing of the insulin receptor beta subunit is associated with insulin-induced receptor down-regulation.
Topics: Animals; Blotting, Western; Cells, Cultured; Chloroquine; Cycloheximide; Cysteine Endopeptidases; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Insulin; Insulin Antagonists; Leucine; Leupeptins; Mice; Peptide Fragments; Receptor, Insulin | 1991 |
Activation of intracellular calcium-activated neutral proteinase in erythrocytes and its inhibition by exogenously added inhibitors.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blood Proteins; Calcimycin; Calcium; Calpain; Enzyme Activation; Erythrocytes; Female; In Vitro Techniques; Leucine; Leupeptins; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rabbits | 1991 |
Effect of calpain inhibitors on the invasion of human erythrocytes by the parasite Plasmodium falciparum.
Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Erythrocytes; Humans; Leucine; Leupeptins; Oligopeptides; Pepstatins; Plasmodium falciparum | 1991 |
The effect of lysosomal inhibitors on protein degradation in cat hepatocyte monolayers.
Topics: Ammonium Chloride; Animals; Cats; Cells, Cultured; Cycloheximide; Insulin; Leucine; Leupeptins; Liver; Lysosomes; Proteins | 1991 |
Potentiation of the cytotoxicity of peplomycin against Ehrlich ascites carcinoma by bleomycin hydrolase inhibitors.
Topics: Animals; Bleomycin; Carcinoma, Ehrlich Tumor; Cell Survival; Cysteine Endopeptidases; Drug Synergism; Female; Glycoside Hydrolases; Leucine; Leupeptins; Mice; Oligopeptides; Peplomycin | 1987 |
Inhibition of proteolysis blocks anterograde-retrograde conversion of axonally transported vesicles.
Topics: Animals; Axonal Transport; Axons; Leucine; Leupeptins; Male; Microscopy, Electron; Oligopeptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve | 1988 |
Morphological, physiological and biochemical alterations in livers of rodents induced by protease inhibitors: a comparison with old livers.
Topics: Aging; Animals; Biological Transport; Dolichols; Leucine; Leupeptins; Liver; Male; Mice; Mice, Inbred C57BL; Ouabain; Protease Inhibitors; Rats; Rats, Inbred F344; Rats, Inbred Strains; Sulfobromophthalein | 1989 |
The thiol proteinase inhibitors improve the abnormal rapid down-regulation of protein kinase C and the impaired natural killer cell activity in (Chediak-Higashi syndrome) beige mouse.
Topics: Animals; Calpain; Chediak-Higashi Syndrome; Cysteine Proteinase Inhibitors; Cytotoxicity, Immunologic; Disease Models, Animal; Killer Cells, Natural; Killer Factors, Yeast; Leucine; Leupeptins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Protein Biosynthesis; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1989 |
Elucidation of cathepsin B-like activity associated with extracts of human myelin basic protein.
Topics: 4-Chloromercuribenzenesulfonate; Cathepsin B; Cathepsins; Dithioerythritol; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Leucine; Leupeptins; Myelin Basic Protein; Protease Inhibitors | 1985 |
Differences in induction of lysosomal protease activity by protease inhibitors in B16 melanoma cell lines.
Topics: Acid Phosphatase; Animals; Cathepsin B; Enzyme Induction; Leucine; Leupeptins; Melanoma, Experimental; Mice; Oligopeptides; Pepstatins; Peptide Hydrolases; Protease Inhibitors; Subcellular Fractions; Tumor Cells, Cultured | 1989 |
Cleavage site of calcium-dependent protease in human platelet membrane glycoprotein Ib.
Topics: Animals; Calcimycin; Calcium; Calpain; Chickens; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Humans; Isoelectric Point; Leucine; Leupeptins; Membrane Proteins; Molecular Weight; Phenotype; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins | 1986 |
Regulation of the breakdown rates of biotin-containing proteins in Swiss 3T3-L1 cells.
Topics: Adenine; Biotin; Cell Line; Electrophoresis, Polyacrylamide Gel; Insulin; Leucine; Leupeptins; Proteins | 1988 |
A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.
Topics: Animals; Cysteine Endopeptidases; Hemoglobins; Leucine; Leupeptins; Malaria; Microscopy, Electron; Molecular Weight; Plasmodium falciparum; Protease Inhibitors | 1988 |
Involvement of thiol proteases in galactosialidosis.
Topics: beta-Galactosidase; Cathepsin B; Cathepsin H; Cathepsins; Cells, Cultured; Coumarins; Cysteine Endopeptidases; Diazomethane; Dipeptides; Endopeptidases; Fibroblasts; Galactosidases; Humans; Leucine; Leupeptins; Neuraminidase; Protease Inhibitors | 1986 |
Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis.
Topics: Animals; Cathepsin B; Cathepsins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Endopeptidases; Female; Fibrinolysis; Leucine; Leupeptins; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Peptide Hydrolases; Plasminogen Activators; Plasminogen Inactivators; Protease Inhibitors; Serine Endopeptidases; Thrombin; Thrombosis | 1986 |
Suppression of neurofilament degradation by protease inhibitors in experimental spinal cord injury.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Intermediate Filament Proteins; Leucine; Leupeptins; Male; Nerve Tissue Proteins; Neurofilament Proteins; Oligopeptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Cord Injuries | 1987 |
Partial purification and characterization of cysteine proteinases in eccrine sweat.
Topics: Benzoylarginine-2-Naphthylamide; Chromatography, Affinity; Chromatography, Gel; Cysteine Endopeptidases; Dithiothreitol; Eccrine Glands; Edetic Acid; Endopeptidases; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoenzymes; Leucine; Leupeptins; Molecular Weight; Sweat; Sweat Glands | 1987 |
Degradation of endocytosed dermatan sulfate proteoglycan in human fibroblasts.
Topics: Ammonium Chloride; Biological Transport; Cells, Cultured; Chondroitin; Chondroitin Sulfate Proteoglycans; Cycloheximide; Dermatan Sulfate; Diazomethane; Endocytosis; Fibroblasts; Half-Life; Humans; Kinetics; Leucine; Leupeptins; Lysosomes; Molecular Weight; Protease Inhibitors; Proteoglycans; Sulfates | 1988 |
Morphometric assessment of drug effects in experimental spinal cord injury.
Topics: Animals; Axons; Leucine; Leupeptins; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Spinal Cord Injuries | 1986 |
Induction and inhibition of cathepsin B and hemoglobin-hydrolase activity in murine B16 melanoma by thiol protease inhibitors.
Topics: Animals; Antipain; Cathepsin B; Kinetics; Leucine; Leupeptins; Melanoma, Experimental; Mice; Oligopeptides; Peptide Hydrolases; Protease Inhibitors | 1986 |
Mode of action of bestatin and leupeptin to induce the accumulation of acid soluble peptides in rat liver in vivo and the properties of the accumulated peptides. The important role of bestatin- and leupeptin-sensitive proteases in the protein degradation
Topics: Aminopeptidases; Animals; Glucagon; Kinetics; Leucine; Leupeptins; Liver; Male; Models, Biological; Oligopeptides; Peptide Mapping; Peptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Solubility | 1987 |
Leucine aminopeptidase and hatching of Schistosoma mansoni eggs.
Topics: Animals; Cold Temperature; Darkness; Leucine; Leucyl Aminopeptidase; Leupeptins; Ovum; Schistosoma mansoni; Sodium Chloride | 1986 |
Isolation of two forms of the high-molecular-mass serine protease, ingensin, from porcine skeletal muscle.
Topics: Animals; Antipain; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, High Pressure Liquid; Coumarins; Cysteine Endopeptidases; Endopeptidases; Isoenzymes; Leucine; Leupeptins; Multienzyme Complexes; Muscles; Oligopeptides; Pepstatins; Proteasome Endopeptidase Complex; Sodium Dodecyl Sulfate; Swine | 1985 |
Molecular forms of GM2-activator protein. A study on its biosynthesis in human skin fibroblasts.
Topics: Cells, Cultured; Endocytosis; Enzyme-Linked Immunosorbent Assay; Fibroblasts; G(M2) Activator Protein; G(M2) Ganglioside; Gangliosides; Gangliosidoses; Humans; Kinetics; Leucine; Leupeptins; Lysosomes; Pepstatins; Phenylmethylsulfonyl Fluoride; Protein Biosynthesis; Skin; Tritium | 1985 |
The digestion of phagocytosed collagen is inhibited by the proteinase inhibitors leupeptin and E-64.
Topics: 2,2'-Dipyridyl; Animals; Ascorbic Acid; Bone and Bones; Collagen; Culture Techniques; Cycloheximide; Cytochalasin B; Fibroblasts; Leucine; Leupeptins; Mice; Microscopy, Electron; Oligopeptides; Phagocytosis; Vacuoles | 1985 |
The fate of the surface protein gp70 during entry of retrovirus into mouse fibroblasts.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glucosamine; Kinetics; Leucine; Leupeptins; Mice; Retroviridae; Retroviridae Proteins; Tritium; Viral Envelope Proteins | 1985 |
Inhibition of cell adhesion in Dictyostelium discoideum by tunicamycin is prevented by leupeptin.
Topics: Aspartic Acid Endopeptidases; Cell Adhesion; Dictyostelium; Edetic Acid; Endopeptidases; Glucosamine; Leucine; Leupeptins; Oligopeptides; Tunicamycin | 1983 |
Similar effects of various low-molecular-weight enzyme inhibitors on enzyme networks in dystrophic mice.
Topics: Alkaline Phosphatase; Aminopeptidases; Animals; Esterases; Forelimb; Glutamyl Aminopeptidase; Glycine; Hindlimb; Leucine; Leucyl Aminopeptidase; Leupeptins; Male; Mice; Mice, Mutant Strains; Molecular Weight; Muscles; Muscular Dystrophy, Animal; Oligopeptides; Spleen | 1984 |
Inhibition of proteolysis in rat yolk sac as a cause of teratogenesis. Effects of leupeptin in vitro and in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Leucine; Leupeptins; Oligopeptides; Pinocytosis; Povidone; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Yolk Sac | 1983 |
Degradation of proteins in rat liver mitochondrial outer membrane transplanted into different cell types. Evidence for alternative processing.
Topics: Ammonium Chloride; Animals; Cell Line; Cricetinae; Cycloheximide; Half-Life; Humans; Intracellular Membranes; Leucine; Leupeptins; Liver Neoplasms, Experimental; Membrane Proteins; Mice; Microscopy, Fluorescence; Mitochondria, Liver; Rats | 1984 |
The role of proteases in stratum corneum: involvement in stratum corneum desquamation.
Topics: Antipain; Aprotinin; Detergents; Endopeptidases; Epidermis; Ethylmaleimide; Humans; Leucine; Leupeptins; Oligopeptides; Pepstatins; Protease Inhibitors; Sunburn | 1994 |
Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs.
Topics: Animals; Aprotinin; Captopril; Dose-Response Relationship, Drug; Endopeptidases; Guinea Pigs; Leucine; Leupeptins; Lung; Male; Muscle Relaxation; Muscle, Smooth; Perfusion; Protease Inhibitors; Time Factors; Trachea; Trypsin Inhibitors; Vasoactive Intestinal Peptide | 1993 |
Excystment of Paragonimus westermani metacercariae by endogenous cysteine protease.
Topics: Animals; Chromatography, Ion Exchange; Collagen; Coumarins; Cysteine Endopeptidases; Dipeptides; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Fibronectins; Hydrogen-Ion Concentration; Iodoacetamide; Leucine; Leupeptins; Myosins; Oligopeptides; Pancreatic Elastase; Paragonimus; Temperature; Trypsin | 1995 |
Role of calcium-activated neutral protease (calpain) in cell death in cultured neonatal rat cardiomyocytes during metabolic inhibition.
Topics: Animals; Animals, Newborn; Calcium; Calpain; Cell Death; Cells, Cultured; Chromatography, Affinity; Chromatography, Ion Exchange; Cysteine Proteinase Inhibitors; Enzyme Activation; Leucine; Leupeptins; Myocardium; Protease Inhibitors; Rats; Rats, Wistar | 1995 |
Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites.
Topics: Animals; Antimalarials; Chymotrypsin; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Fluorescent Dyes; Globins; Humans; Hydrolysis; Leucine; Leupeptins; Oligopeptides; Pepstatins; Plasmodium falciparum; Vacuoles | 1995 |
Trichomonas vaginalis: amoeboid and flagellated forms synthesize similar proteinases.
Topics: Animals; Caseins; Culture Media; Cysteine Proteinase Inhibitors; Diazomethane; Endopeptidases; Leucine; Leupeptins; Lipoproteins; Trichomonas vaginalis | 1995 |
Effects of exogenous protease effectors on beef tenderness development and myofibrillar degradation and solubility.
Topics: Animals; Calcimycin; Calcium; Calpain; Cathepsins; Cattle; Cysteine Proteinase Inhibitors; Diazomethane; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glycoproteins; Leucine; Leupeptins; Male; Meat; Muscle Proteins; Muscles; Octoxynol; Pepstatins; Phenylmethylsulfonyl Fluoride; Postmortem Changes; Solubility | 1994 |
Leupeptin and E-64, inhibitors of cysteine proteinases, prevent gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts.
Topics: Animals; Cells, Cultured; Cysteine Proteinase Inhibitors; Fibroblasts; Gentamicins; Leucine; Leupeptins; Lysosomes; Phospholipids; Rats | 1994 |
Mechanism of trimethylamine-induced inhibition of macromolecular synthesis by mouse embryos in culture.
Topics: Animals; Blood; Culture Techniques; Embryo, Mammalian; Extremities; Female; Insulin; Insulin-Like Growth Factor II; Leucine; Leupeptins; Male; Methylamines; Mice; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sucrose; Vitamin A; Yolk Sac | 1994 |
Effect of high hydrostatic pressure on the conversion of alpha-connectin to beta-connectin.
Topics: Animals; Antibodies, Monoclonal; Calcium; Calpain; Connectin; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Hydrostatic Pressure; Leucine; Leupeptins; Molecular Weight; Muscle Proteins; Muscles; Protein Kinases; Rabbits | 1993 |
Proteinases in renal cell death.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Antipain; Carboxypeptidases; Cathepsin A; Cathepsin B; Cell Death; Coumarins; Cysteine; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endopeptidases; Hydrocarbons, Fluorinated; Hydroquinones; Isocoumarins; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Leucine; Leupeptins; Lysosomes; Membrane Potentials; Pepstatins; Peroxides; Rabbits; Reactive Oxygen Species; Serine Proteinase Inhibitors; tert-Butylhydroperoxide; Tosyllysine Chloromethyl Ketone | 1996 |
The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Cathepsin B; Computer Simulation; Crystallography, X-Ray; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Fruit; Hydrogen Bonding; Leucine; Leupeptins; Models, Molecular; Molecular Sequence Data; Mutation; Oligopeptides; Papain; Plant Proteins; Protein Processing, Post-Translational; Protein Structure, Secondary; Sequence Homology, Amino Acid | 1996 |
Characterization of the leupeptin-inactivating enzyme from Streptomyces exfoliatus SMF13 which produces leupeptin.
Topics: Amino Acid Sequence; Chromatography; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Leucine; Leupeptins; Metalloendopeptidases; Microscopy, Electron, Scanning; Molecular Weight; Peptide Fragments; Phenanthrolines; Streptomyces; Substrate Specificity | 1998 |
Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.
Topics: Adenosine Triphosphate; Animals; Calcium; Calpain; Cathepsin B; Cathepsin D; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Deoxyglucose; Dexamethasone; Leucine; Leupeptins; Methylamines; Mifepristone; Multienzyme Complexes; Muscle, Skeletal; Proteasome Endopeptidase Complex; Proteins; Rats; Tyrosine; Ubiquitins | 1998 |
Colocalization and membrane association of murine hepatitis virus gene 1 products and De novo-synthesized viral RNA in infected cells.
Topics: Animals; Cell Line; Cell Membrane Permeability; Chlorides; Cysteine Proteinase Inhibitors; DNA-Directed RNA Polymerases; HeLa Cells; Humans; Intracellular Membranes; Leucine; Leupeptins; Mice; Murine hepatitis virus; Rabbits; RNA, Viral; Staining and Labeling; Time Factors; Viral Proteins; Zinc Compounds | 1999 |
A role for the proteasome in the light response of the timeless clock protein.
Topics: Acetylcysteine; Animals; Biological Clocks; Cells, Cultured; Circadian Rhythm; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Darkness; Drosophila; Drosophila Proteins; Feedback; Insect Proteins; Leucine; Leupeptins; Light; Multienzyme Complexes; Neurons; Phosphorylation; Phosphotyrosine; Protease Inhibitors; Proteasome Endopeptidase Complex; Ubiquitins | 1999 |
Transgenic Arabidopsis leaf tissue expressing a modified oryzacystatin shows resistance to the field slug Deroceras reticulatum (Müller).
Topics: Animals; Arabidopsis; Cystatins; Cysteine Proteinase Inhibitors; Leucine; Leupeptins; Mollusca; Plant Leaves; Plants, Genetically Modified; Recombinant Proteins | 1999 |
Effect of the selective and non-selective cysteine protease inhibitors on the intracellular processing of interleukin 6 by HEPG2 cells.
Topics: Cathepsin B; Cathepsins; Cell Membrane Permeability; Cysteine Proteinase Inhibitors; Dipeptides; Humans; Interleukin-6; Intracellular Fluid; Iodine Radioisotopes; Isotope Labeling; Ketones; Leucine; Leupeptins; Recombinant Proteins; Time Factors; Tumor Cells, Cultured | 1999 |
Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Leucine; Leupeptins; Multienzyme Complexes; Neurons; Oligopeptides; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Rats, Wistar; Ubiquitins | 2000 |
Effect of protease inhibitors on angiotensin-converting enzyme activity in human T-lymphocytes.
Topics: Adult; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Calpain; Captopril; Cathepsins; Chymotrypsin; Cysteine Proteinase Inhibitors; Humans; Leucine; Leupeptins; Lisinopril; Lymphocyte Activation; Male; Oligopeptides; Peptidyl-Dipeptidase A; Protease Inhibitors; T-Lymphocytes | 2000 |
Inhibition of apoptosis in cultured porcine granulosa cells by inhibitors of caspase and serine protease activity.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Membrane; Cysteine Proteinase Inhibitors; DNA Fragmentation; Electrophoresis, Agar Gel; Estradiol; Female; Flow Cytometry; Granulosa Cells; Leucine; Leupeptins; Microscopy, Fluorescence; Phenylmethylsulfonyl Fluoride; Progesterone; Radioimmunoassay; Regression Analysis; Serine Proteinase Inhibitors; Swine; Tosylphenylalanyl Chloromethyl Ketone | 2000 |
Possible involvement of EBV-mediated alpha-fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Aprotinin; Autoantigens; Carrier Proteins; Caspases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Herpesvirus 4, Human; Humans; Hydrolysis; Leucine; Leupeptins; Microfilament Proteins; Molecular Weight; Organ Specificity; Pepstatins; Sjogren's Syndrome; Trans-Activators; Tumor Cells, Cultured; Viral Proteins; Virus Activation | 2001 |
Specific inhibitors prevent proteolytic degradation of recombinant proteins expressed in High Five cells.
Topics: Animals; Baculoviridae; Cell Line; Cysteine Proteinase Inhibitors; Genetic Vectors; Insecta; Leucine; Leupeptins; Recombinant Proteins; Transfection | 2001 |
Studies on the aminopeptidase activities of Porphyromonas gingivalis.
Topics: Adhesins, Bacterial; Aminopeptidases; Anti-Bacterial Agents; Carbon Radioisotopes; Cathepsins; Chromogenic Compounds; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptidyl Peptidase 4; Gingipain Cysteine Endopeptidases; Guanidines; Hemagglutinins; Humans; Hydroxamic Acids; Leucine; Leupeptins; Mutation; Oligopeptides; Peptides; Porphyromonas gingivalis; Protease Inhibitors; Radiopharmaceuticals | 2001 |
Stage-specific antimalarial activity of cysteine protease inhibitors.
Topics: Animals; Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Gene Expression Regulation, Developmental; Hemoglobins; Hydrolysis; Leucine; Leupeptins; Plasmodium falciparum; Time Factors | 2002 |
Impact of cysteine proteinase inhibition in midgut fluid and oral secretion on fecundity and pollen consumption of western corn rootworm (Diabrotica virgifera virgifera).
Topics: Animals; Coleoptera; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Digestive System; Eating; Female; Fertility; Leucine; Leupeptins; Male; Oligopeptides; Pollen; Zea mays | 2003 |
Involvement of cysteine proteinases in excystment of Paragonimus ohirai metacercariae induced by sodium cholate and A23187.
Topics: Animals; Calcimycin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Ionophores; Leucine; Leupeptins; Paragonimus; Parasitology; Reproduction; Serine Proteinase Inhibitors; Sodium Cholate | 2003 |
The calpain-calpastatin system and the calcium paradox in the isolated perfused pigeon heart.
Topics: Animals; Antipain; Barium; Calcium; Calcium-Binding Proteins; Calpain; Cobalt; Columbidae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Heart; In Vitro Techniques; Kinetics; Leucine; Leupeptins; Magnesium; Manganese; Molecular Weight; Myocardium; Nickel; Phenylmethylsulfonyl Fluoride; Strontium; Time Factors | 2003 |
Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.
Topics: Amino Acid Sequence; Animals; Calpain; Catalytic Domain; Cathepsin K; Cathepsins; Crystallization; Crystallography, X-Ray; Cysteine Proteinase Inhibitors; Glycoproteins; Leucine; Leupeptins; Molecular Sequence Data; Papain; Protein Structure, Tertiary; Rats | 2004 |
Enzymatic characterization of a cubilin-related serine proteinase from the hard tick Haemaphysalis longicornis.
Topics: Animals; Antipain; Chromogenic Compounds; Escherichia coli; Fluorescent Dyes; Hydrogen-Ion Concentration; Ixodidae; Leucine; Leupeptins; Pepstatins; Phenylmethylsulfonyl Fluoride; Recombinant Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Temperature | 2004 |
A cysteine-activated protease isolated from Todarodes pacificus squid degrades collagen below its denaturation temperature.
Topics: Amino Acid Sequence; Animals; Cattle; Collagen; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Decapodiformes; Hydrogen-Ion Concentration; Leucine; Leupeptins; Molecular Sequence Data; Molecular Weight; Muscles; Octopodiformes; Protein Denaturation; Snails; Species Specificity; Temperature | 2004 |
Phytomonas serpens: cysteine peptidase inhibitors interfere with growth, ultrastructure and host adhesion.
Topics: Animals; Antibodies, Protozoan; Antipain; Cell Division; Cells, Cultured; Cystatins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Detergents; Flow Cytometry; Heteroptera; Immunohistochemistry; Iodoacetamide; Leucine; Leupeptins; Membrane Proteins; Microscopy, Electron; Octoxynol; Plant Proteins; Polyethylene Glycols; Protozoan Proteins; Salivary Glands; Trypanosomatina | 2006 |
High-temperature liquid chromatography coupled on-line to a continuous-flow biochemical screening assay with electrospray ionization mass spectrometric detection.
Topics: Cathepsin B; Chromatography, Liquid; Dipeptides; Drug Stability; Hot Temperature; Leucine; Leupeptins; Online Systems; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tea | 2005 |
Cathepsin L plays an important role in the lysosomal degradation of L-lactate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Cathepsin L; Cathepsins; Chromatography, Gel; Cystatins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; L-Lactate Dehydrogenase; Leucine; Leupeptins; Lysosomes; Male; Molecular Sequence Data; Rats; Rats, Wistar; Sequence Alignment | 2006 |
Babesia bovis: effects of cysteine protease inhibitors on in vitro growth.
Topics: Animals; Babesia bovis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Erythrocytes; Leucine; Leupeptins | 2007 |
Cloning, site-directed mutagenesis and expression of cathepsin L-like cysteine protease from Uronema marinum (Ciliophora: Scuticociliatida).
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Protozoan; Enzyme Stability; Escherichia coli; Gene Expression; Gene Library; Hydrogen-Ion Concentration; Leucine; Leupeptins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligohymenophorea; Protein Folding; Protozoan Proteins; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2007 |
Cysteine peptidases in the tomato trypanosomatid Phytomonas serpens: influence of growth conditions, similarities with cruzipain and secretion to the extracellular environment.
Topics: Animals; Blotting, Western; Culture Media; Cystatins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Hemiptera; Hydrogen-Ion Concentration; Leucine; Leupeptins; Microscopy, Fluorescence; Protozoan Proteins; Reducing Agents; Salivary Proteins and Peptides; Solanum lycopersicum; Trypanosomatina | 2008 |
The comparison of parathyroid hormone degradation effect by various protease inhibitors in blood specimen.
Topics: Aprotinin; Blood Specimen Collection; Edetic Acid; Female; Humans; Leucine; Leupeptins; Male; Parathyroid Hormone; Protease Inhibitors; Time Factors | 2009 |
CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization.
Topics: Autophagy; bcl-X Protein; Caspase 8; Caspases; CD11b Antigen; Cell Survival; Chemokine CCL2; Cytokines; Humans; Interleukin-6; Leucine; Leukocytes, Mononuclear; Leupeptins; Lipopolysaccharide Receptors; Macrophages; Monocytes; Proto-Oncogene Proteins c-bcl-2 | 2009 |
Participation of cysteine protease cathepsin L in the gel disintegration of red bulleye (Priacanthus macracanthus) surimi gel paste.
Topics: Animals; Cathepsin L; Cysteine Proteases; Electrophoresis, Polyacrylamide Gel; Fish Products; Fish Proteins; Gels; Hot Temperature; Hydrolysis; Leucine; Leupeptins; Perciformes; Protease Inhibitors | 2010 |
Collagenolytic activity in sonic extracts of Tannerella forsythia.
Topics: Bacteroides; Calcium Chloride; Cathepsins; Cell Line, Tumor; Chelating Agents; Collagen Type I; Cysteine; Cysteine Proteinase Inhibitors; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Ethylmaleimide; Gelatinases; Humans; Iodoacetamide; Iodoacetic Acid; Leucine; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine Proteinase Inhibitors; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone | 2010 |
Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Biocatalysis; Blotting, Western; Calpain; Catalytic Domain; Cysteine Proteinase Inhibitors; Endosomal Sorting Complexes Required for Transport; Ethylmaleimide; Glutathione Transferase; Green Fluorescent Proteins; HEK293 Cells; Humans; Hydrolysis; Immunoprecipitation; Leucine; Leupeptins; Mutation; Oncogene Proteins; Protein Binding; Recombinant Fusion Proteins; Transfection | 2010 |
Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.
Topics: Acetylcysteine; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Nucleolus; Checkpoint Kinase 1; Cyclin-Dependent Kinases; Cyclins; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; Leucine; Leupeptins; Nuclear Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin | 2011 |
Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways.
Topics: Androgens; cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Dihydrotestosterone; Humans; Leucine; Leupeptins; Lysosomes; Male; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Receptors, Androgen; Transcriptome; Up-Regulation | 2013 |
Insertion sequence 1 from calpain-3 is functional in calpain-2 as an internal propeptide.
Topics: Calcium; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; DNA Transposable Elements; Isoenzymes; Leucine; Leupeptins; Muscle Proteins; Protein Conformation; Proteolysis; Recombinant Proteins | 2018 |
In vitro effect of a novel protease inhibitor cocktail on Toxoplasma gondii tachyzoites.
Topics: Analysis of Variance; Animals; Aprotinin; Culture Media, Serum-Free; Cysteine Proteinase Inhibitors; Drug Combinations; Hep G2 Cells; Humans; Leucine; Leupeptins; Mice; Microscopy, Electron, Transmission; Organelles; Pilot Projects; Protease Inhibitors; Serine Proteinase Inhibitors; Statistics, Nonparametric; Sulfones; Toxoplasma | 2020 |