leupeptin has been researched along with cycloheximide in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bang, YJ; Danielpour, D; Kim, KY; Kim, SJ; Myers, CE; O'Reilly, MA; Trepel, JB | 1 |
| Bianchi, CP; Booz, GW | 1 |
| Homma, S; Oppenheim, RW; Prevette, D; Tytell, M | 1 |
| Collins, AR; Grubb, A | 1 |
| Knutson, VP | 1 |
| Edwards, RH; MacLennan, PA; McArdle, A | 1 |
| Mercer, JR; Silva, SV | 1 |
| Hoppe, W; Kresse, H; Rauch, U | 1 |
| Ballard, FJ | 1 |
| Kovács, AL; Kovács, J; László, L | 1 |
| Beertsen, W; Everts, V; Tigchelaar-Gutter, W | 1 |
| Khairallah, EA | 1 |
| Grinde, B; Jahnsen, R | 1 |
| Hashida, S; Katunuma, N; Khairallah, EA; Kominami, E | 1 |
| Dunn, WA; Hubbard, AL | 1 |
| Curtis, AS; Forrester, JV; Lawrie, F; McInnes, C | 1 |
| Amenta, JS; Mayer, RJ; Russell, SM | 1 |
| Delaissé, JM; Kishore, BK; Montenez, JP; Tulkens, PM | 1 |
| Lodish, HF; Neumann, D; Watowich, SS; Wikström, L | 1 |
| Biber, J; Lederer, E; Murer, H; Pfister, MF; Ruf, I; Stange, G; Ziegler, U | 1 |
| Ahmad, F; Blaesse, P; Kaila, K; Puskarjov, M | 1 |
22 other study(ies) available for leupeptin and cycloheximide
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.
Topics: 1-Methyl-3-isobutylxanthine; Aprotinin; Blotting, Northern; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leupeptins; Male; Pentoxifylline; Phenylmethylsulfonyl Fluoride; Prostatic Neoplasms; RNA, Neoplasm; Theophylline; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Stimulation-enhanced 3-O-methylglucose efflux from the frog sartorius: kinetics and properties of the system.
Topics: 3-O-Methylglucose; Animals; Calcium; Cycloheximide; Dipeptides; Electric Stimulation; Humans; Kinetics; Leupeptins; Male; Methylglucosides; Muscles; Phloretin; Rana pipiens; Tetradecanoylphorbol Acetate | 1992 |
Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes.
Topics: Animals; Cell Survival; Chick Embryo; Chloroquine; Curare; Cycloheximide; Dactinomycin; Ganglia, Spinal; Gene Expression; Genotype; Leupeptins; Microscopy, Electron; Motor Neurons; Protein Biosynthesis; Puromycin; RNA; Spinal Cord | 1990 |
Inhibitory effects of recombinant human cystatin C on human coronaviruses.
Topics: Antiviral Agents; Cathepsin B; Cells, Cultured; Coronaviridae; Cycloheximide; Cystatin C; Cystatins; Escherichia coli; Humans; Leupeptins; Papain; Recombinant Proteins; Virus Replication | 1991 |
Proteolytic processing of the insulin receptor beta subunit is associated with insulin-induced receptor down-regulation.
Topics: Animals; Blotting, Western; Cells, Cultured; Chloroquine; Cycloheximide; Cysteine Endopeptidases; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Insulin; Insulin Antagonists; Leucine; Leupeptins; Mice; Peptide Fragments; Receptor, Insulin | 1991 |
Effects of calcium on protein turnover of incubated muscles from mdx mice.
Topics: Animals; Calcium; Cycloheximide; Kinetics; Leupeptins; Methylamines; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscles; Muscular Dystrophy, Animal; Proteins; Tyrosine | 1991 |
The effect of lysosomal inhibitors on protein degradation in cat hepatocyte monolayers.
Topics: Ammonium Chloride; Animals; Cats; Cells, Cultured; Cycloheximide; Insulin; Leucine; Leupeptins; Liver; Lysosomes; Proteins | 1991 |
Degradation of endocytosed dermatan sulfate proteoglycan in human fibroblasts.
Topics: Ammonium Chloride; Biological Transport; Cells, Cultured; Chondroitin; Chondroitin Sulfate Proteoglycans; Cycloheximide; Dermatan Sulfate; Diazomethane; Endocytosis; Fibroblasts; Half-Life; Humans; Kinetics; Leucine; Leupeptins; Lysosomes; Molecular Weight; Protease Inhibitors; Proteoglycans; Sulfates | 1988 |
Regulation of protein breakdown by epidermal growth factor in A431 cells.
Topics: Adenine; Ammonium Chloride; Autolysis; Carcinoma, Squamous Cell; Cell Line; Cycloheximide; Epidermal Growth Factor; Fibroblasts; Humans; Hydrogen-Ion Concentration; Insulin; Leupeptins; Lung; Proteins; Time Factors; Vinblastine | 1985 |
Effect of amino acids and cycloheximide on changes caused by vinblastine, leupeptin and methylamine in the autophagic/lysosomal system of mouse hepatocytes in vivo.
Topics: Amino Acids; Animals; Autophagy; Cycloheximide; Leupeptins; Liver; Lysosomes; Male; Methylamines; Mice; Organoids; Phagocytosis; Proteins; Vacuoles; Vinblastine | 1985 |
The digestion of phagocytosed collagen is inhibited by the proteinase inhibitors leupeptin and E-64.
Topics: 2,2'-Dipyridyl; Animals; Ascorbic Acid; Bone and Bones; Collagen; Culture Techniques; Cycloheximide; Cytochalasin B; Fibroblasts; Leucine; Leupeptins; Mice; Microscopy, Electron; Oligopeptides; Phagocytosis; Vacuoles | 1985 |
Quantitative assessment of the contribution of autophagy to intracellular protein breakdown.
Topics: Animals; Autolysis; Cathepsins; Cycloheximide; Cytoplasm; Drug Administration Schedule; Fasting; Homeostasis; Leupeptins; Liver; Lysosomes; Microtubules; Protein Conformation; Proteins; Rats | 1985 |
Effects of protein-degradation inhibitors on the inactivation of tyrosine aminotransferase, tryptophan oxygenase and benzopyrene hydroxylase in isolated rat hepatocytes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Cell Separation; Cycloheximide; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Leupeptins; Liver; Male; Methylamines; Oligopeptides; Rats; Rats, Inbred Strains; Tryptophan Oxygenase; Tyrosine Transaminase | 1982 |
Sequestration of cytoplasmic enzymes in an autophagic vacuole-lysosomal system induced by injection of leupeptin.
Topics: Acid Phosphatase; Aminopeptidases; Animals; Autophagy; Cathepsin D; Cathepsin H; Cathepsins; Centrifugation, Density Gradient; Cycloheximide; Cysteine Endopeptidases; Cytoplasm; Dexamethasone; Fructose-Bisphosphate Aldolase; Kinetics; L-Lactate Dehydrogenase; Leupeptins; Liver; Lysosomes; Male; Oligopeptides; Organoids; Phagocytosis; Rats; Rats, Inbred Strains; Tyrosine Transaminase; Vacuoles | 1983 |
Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics.
Topics: Animals; Cycloheximide; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Horseradish Peroxidase; In Vitro Techniques; Kinetics; Leupeptins; Ligands; Liver; Male; Microscopy, Electron; Rats; Receptors, Cell Surface; Subcellular Fractions | 1984 |
Adhesion of cells to polystyrene surfaces.
Topics: Animals; Bacteriological Techniques; Cell Adhesion; Cricetinae; Culture Media; Cycloheximide; Kidney; Leupeptins; Oxidation-Reduction; Polystyrenes; Trypsin | 1983 |
Degradation of proteins in rat liver mitochondrial outer membrane transplanted into different cell types. Evidence for alternative processing.
Topics: Ammonium Chloride; Animals; Cell Line; Cricetinae; Cycloheximide; Half-Life; Humans; Intracellular Membranes; Leucine; Leupeptins; Liver Neoplasms, Experimental; Membrane Proteins; Mice; Microscopy, Fluorescence; Mitochondria, Liver; Rats | 1984 |
Increased activities of cathepsin B and other lysosomal hydrolases in fibroblasts and bone tissue cultured in the presence of cysteine proteinases inhibitors.
Topics: Animals; Bone Resorption; Cathepsin B; Cells, Cultured; Culture Techniques; Cycloheximide; Fibroblasts; Hydrolases; Leupeptins; Mice; Parathyroid Hormone; Protein Biosynthesis; Proteins; Rats; Rats, Wistar; Skull; Time Factors | 1994 |
Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.
Topics: 3T3 Cells; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cycloheximide; Endoplasmic Reticulum; Golgi Apparatus; Hexosaminidases; Leupeptins; Lysosomes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Peptide Fragments; Receptors, Erythropoietin | 1993 |
Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Compartmentation; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Kidney; Leupeptins; Lysosomes; Microscopy, Confocal; Multienzyme Complexes; Opossums; Parathyroid Hormone; Phosphates; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type II; Symporters | 1998 |
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Ionophores; Calpain; Cycloheximide; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emetine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ionomycin; K Cl- Cotransporters; Leupeptins; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Statistics, Nonparametric; Symporters; Valine | 2012 |