Page last updated: 2024-08-25

leupeptin and chymostatin

leupeptin has been researched along with chymostatin in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's9 (32.14)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeMartino, GN; Dick, LR; Moomaw, CR; Slaughter, CA1
Olaya, P; Wasserman, M1
Grisolía, S; Hernández-Yago, J; Knecht, E; Vargas, JL1
Fesus, L; Tarcsa, E1
Bajusz, S; Makara, GB; Nagy, I; Rappay, G1
Beynon, RJ; Chetland, J; Galpin, IJ; Place, GA1
Katsunuma, N; Morita, K; Nakanishi, A; Oka, M1
Factorovich, Y; Puri, J1
Kurita, Y; Nakao, H; Ogawa, H; Takamori, K; Tsuboi, R1
Dluzewski, AR; Gratzer, WB; Rangachari, K; Wilson, RJ1
Goto, I; Kuroiwa, Y; Shinno, N1
Ishii, S; Murao, S; Numakunai, T; Yokosawa, H1
Gagnon, C; Veeraragavan, K1
Ichikawa, S; Murao, S; Oda, K; Shibata, T; Takehara, Y; Tamada, H1
Odessey, R1
Grinde, B; Jahnsen, R1
Fujii, S; Hitomi, Y; Honda, T; Niinobe, M1
Bates, PJ; Coetzee, GA; Van der Westhuyzen, DR1
Horii, I; Koyama, J; Nomura, J; Suzuki, Y1
Cha, SH; Choi, DS; Kim, YB; Park, YK; Sok, DE1
Haire, MF; Mykles, DL1
Rosenthal, PJ1
Fibach, E; Konijn, AM; Vaisman, B1
Denda, M; Koyama, J; Nakanishi, J; Nomura, J; Sato, J1
Fagard, R; Lijnen, P; Petrov, V1
Kidane, TZ; Linder, MC; Sauble, E1
Chakraborti, S; Chakraborti, T; Das, S; Mandai, M1
Billinger, E; Johansson, G1

Other Studies

28 other study(ies) available for leupeptin and chymostatin

ArticleYear
Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome).
    Biochemistry, 1991, Mar-12, Volume: 30, Issue:10

    Topics: Amino Acid Sequence; Animals; Antipain; Cattle; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Erythrocytes; Humans; Insulin; Kinetics; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Oxidation-Reduction; Pentamidine; Proteasome Endopeptidase Complex

1991
Effect of calpain inhibitors on the invasion of human erythrocytes by the parasite Plasmodium falciparum.
    Biochimica et biophysica acta, 1991, Apr-15, Volume: 1096, Issue:3

    Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Erythrocytes; Humans; Leucine; Leupeptins; Oligopeptides; Pepstatins; Plasmodium falciparum

1991
Cooperation of lysosomes and inner mitochondrial membrane in the degradation of carbamoyl phosphate synthetase and other proteins.
    Biochimica et biophysica acta, 1990, Jun-20, Volume: 1034, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Enzyme Activation; Glutamates; Hydrogen-Ion Concentration; Intracellular Membranes; Leupeptins; Lysosomes; Mitochondria, Liver; Oligopeptides; Pepstatins; Peptide Hydrolases; Protease Inhibitors; Rats; Substrate Specificity

1990
Formation of N epsilon-(gamma-glutamyl)-lysine isodipeptide in Chinese-hamster ovary cells.
    The Biochemical journal, 1989, Nov-01, Volume: 263, Issue:3

    Topics: Animals; Cell Division; Cell Line; Chromatography, Ion Exchange; Cricetinae; Cricetulus; Dipeptides; gamma-Glutamylcyclotransferase; In Vitro Techniques; Leupeptins; Methylamines; Oligopeptides; Proteins; Transglutaminases

1989
Various proteinase inhibitors decrease prolactin and growth hormone release by anterior pituitary cells.
    Life sciences, 1985, Feb-11, Volume: 36, Issue:6

    Topics: Animals; Aprotinin; Cells, Cultured; Dose-Response Relationship, Drug; Female; Growth Hormone; Leupeptins; Oligopeptides; Phenylmethylsulfonyl Fluoride; Pituitary Gland, Anterior; Prolactin; Protease Inhibitors; Rats; Trypsin Inhibitor, Kunitz Soybean

1985
The effect of analogues of chymostatin on lysosomal and non-lysosomal components of protein degradation in isolated hepatocytes.
    Biochimica et biophysica acta, 1987, Aug-13, Volume: 925, Issue:2

    Topics: Adenosine Triphosphate; Animals; Gluconeogenesis; In Vitro Techniques; Leupeptins; Liver; Lysosomes; Male; Oligopeptides; Protease Inhibitors; Rats; Structure-Activity Relationship; Tyrosine Transaminase

1987
Evidence against a possible involvement of the serine, and thiol proteases in the exocytotic mechanism of catecholamine secretion in cultured bovine adrenal medullary cells.
    Biochemistry international, 1986, Volume: 13, Issue:5

    Topics: Adrenal Medulla; Animals; Calcimycin; Carbachol; Catecholamines; Cattle; Cells, Cultured; Cysteine Endopeptidases; Endopeptidases; Exocytosis; Kinetics; Leupeptins; Oligopeptides; Potassium; Serine Endopeptidases

1986
Selective inhibition of antigen presentation to cloned T cells by protease inhibitors.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Nov-15, Volume: 141, Issue:10

    Topics: Animals; Antigen-Presenting Cells; Antipain; Clone Cells; Histocompatibility Antigens Class II; Immunosuppressive Agents; Leupeptins; Metalloendopeptidases; Mice; Oligopeptides; Protease Inhibitors; T-Lymphocytes

1988
Induction and inhibition of cathepsin B and hemoglobin-hydrolase activity in murine B16 melanoma by thiol protease inhibitors.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1986, Volume: 85, Issue:2

    Topics: Animals; Antipain; Cathepsin B; Kinetics; Leucine; Leupeptins; Melanoma, Experimental; Mice; Oligopeptides; Peptide Hydrolases; Protease Inhibitors

1986
Plasmodium falciparum: protease inhibitors and inhibition of erythrocyte invasion.
    Experimental parasitology, 1986, Volume: 62, Issue:3

    Topics: Animals; Chymotrypsin; Erythrocytes; Humans; In Vitro Techniques; Leupeptins; Oligopeptides; Plasmodium falciparum; Protease Inhibitors; Trypsin

1986
Leukocyte protease activities in myotonic dystrophy: studies on effects of protease inhibitors.
    European neurology, 1987, Volume: 26, Issue:2

    Topics: Aspartic Acid Endopeptidases; Endopeptidases; Granulocytes; Humans; Leukocytes; Leupeptins; Mercuric Chloride; Monocytes; Myotonic Dystrophy; Neprilysin; Oligopeptides; Pepstatins; Protease Inhibitors

1987
Sperm chymotrypsin-like enzymes of different inhibitor-susceptibility as lysins in ascidians.
    Experientia, 1987, Aug-15, Volume: 43, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Chymotrypsin; Enzyme Inhibitors; Fertilization; Leupeptins; Male; Oligopeptides; Peptides; Spermatozoa; Urochordata

1987
Leupeptin and chymostatin inhibit mammalian protein methylesterase activity.
    Biochemical and biophysical research communications, 1987, Jan-30, Volume: 142, Issue:2

    Topics: Animals; Kinetics; Leupeptins; Oligopeptides; Protein Methyltransferases; Rats

1987
Effects of proteinase inhibitors on preimplantation embryos in the rat.
    Journal of reproduction and fertility, 1985, Volume: 73, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antipain; Blastocyst; Cystatins; Embryonic Development; Enzyme Inhibitors; Female; Glycopeptides; Leupeptins; Oligopeptides; Pepstatins; Peptides; Pregnancy; Protease Inhibitors; Rats; Rats, Inbred Strains

1985
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniques; Indomethacin; Leupeptins; Lysosomes; Muscles; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Proteins; Quinacrine; Rats; Rats, Inbred Strains; Tyrosine

1985
Effects of protein-degradation inhibitors on the inactivation of tyrosine aminotransferase, tryptophan oxygenase and benzopyrene hydroxylase in isolated rat hepatocytes.
    The Biochemical journal, 1982, Jan-15, Volume: 202, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Cell Separation; Cycloheximide; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Leupeptins; Liver; Male; Methylamines; Oligopeptides; Rats; Rats, Inbred Strains; Tryptophan Oxygenase; Tyrosine Transaminase

1982
Cytochemical demonstrations of protease in human peripheral blood cells by use of new alpha-naphthyl ester substrates.
    Histochemistry, 1983, Volume: 77, Issue:3

    Topics: Chymotrypsin; Histocytochemistry; Humans; Iodoacetates; Iodoacetic Acid; Isoflurophate; Leukocytes; Leupeptins; Lysine; Male; Naphthols; Neutrophils; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Tyrosine

1983
The degradation of endogenous and exogenous proteins in cultured smooth muscle cells.
    Biochimica et biophysica acta, 1982, Nov-24, Volume: 719, Issue:2

    Topics: Animals; Aorta, Thoracic; Cattle; Cell Line; Chloroquine; Chymotrypsin; Embryo, Mammalian; Humans; Kinetics; Leupeptins; Lipoproteins, LDL; Lysosomes; Muscle, Smooth, Vascular; Oligopeptides; Proteins

1982
The role of proteases in stratum corneum: involvement in stratum corneum desquamation.
    Archives of dermatological research, 1994, Volume: 286, Issue:5

    Topics: Antipain; Aprotinin; Detergents; Endopeptidases; Epidermis; Ethylmaleimide; Humans; Leucine; Leupeptins; Oligopeptides; Pepstatins; Protease Inhibitors; Sunburn

1994
Protection by lysosomal hydrolase inhibitors against cytotoxicity of 2-chloroethylethyl sulfide.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:7

    Topics: Alkylation; Animals; Cell Survival; Cells, Cultured; Drug Interactions; Gentamicins; Kanamycin; Leupeptins; Lysosomes; Mice; Mice, Inbred ICR; Mustard Gas; Oligopeptides; Pepstatins; Phospholipases; Protease Inhibitors; Spleen; Streptomycin; Structure-Activity Relationship; T-Lymphocytes

1995
Branched-chain-amino-acid-preferring peptidase activity of the lobster multicatalytic proteinase (proteasome) and the degradation of myofibrillar proteins.
    The Biochemical journal, 1995, Feb-15, Volume: 306 ( Pt 1)

    Topics: Amino Acids, Branched-Chain; Animals; Caseins; Cations; Endopeptidases; Hot Temperature; Leupeptins; Multienzyme Complexes; Muscle Proteins; Muscles; Myofibrils; Nephropidae; Oligopeptides; Peptide Fragments; Protease Inhibitors; Substrate Specificity; Troponin

1995
Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites.
    Experimental parasitology, 1995, Volume: 80, Issue:2

    Topics: Animals; Antimalarials; Chymotrypsin; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Fluorescent Dyes; Globins; Humans; Hydrolysis; Leucine; Leupeptins; Oligopeptides; Pepstatins; Plasmodium falciparum; Vacuoles

1995
Utilization of intracellular ferritin iron for hemoglobin synthesis in developing human erythroid precursors.
    Blood, 1997, Jul-15, Volume: 90, Issue:2

    Topics: Autoradiography; Cells, Cultured; Chloroquine; Enzyme-Linked Immunosorbent Assay; Erythroblasts; Erythroid Precursor Cells; Ferritins; Flow Cytometry; Heme; Hemoglobins; Humans; Iron; Iron Radioisotopes; Kinetics; Leupeptins; Oligopeptides; Protease Inhibitors

1997
Cholesterol sulfate inhibits proteases that are involved in desquamation of stratum corneum.
    The Journal of investigative dermatology, 1998, Volume: 111, Issue:2

    Topics: Animals; Cholesterol Esters; Epidermis; Humans; Ichthyosis, X-Linked; Leupeptins; Male; Mice; Mice, Hairless; Oligopeptides; Serine Proteinase Inhibitors

1998
Effect of protease inhibitors on angiotensin-converting enzyme activity in human T-lymphocytes.
    American journal of hypertension, 2000, Volume: 13, Issue:5 Pt 1

    Topics: Adult; Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Calpain; Captopril; Cathepsins; Chymotrypsin; Cysteine Proteinase Inhibitors; Humans; Leucine; Leupeptins; Lisinopril; Lymphocyte Activation; Male; Oligopeptides; Peptidyl-Dipeptidase A; Protease Inhibitors; T-Lymphocytes

2000
Release of iron from ferritin requires lysosomal activity.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:3

    Topics: Animals; Caco-2 Cells; Chloroquine; Deferoxamine; Enterocytes; Erythroid Cells; Ferritins; Hepatocytes; Humans; Immunoelectrophoresis; Iron; K562 Cells; Leupeptins; Lysosomes; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Rats

2006
Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle.
    Indian journal of biochemistry & biophysics, 2002, Volume: 39, Issue:6

    Topics: Animals; Antipain; Calcium-Transporting ATPases; Cattle; Cell Membrane; Ethylmaleimide; Free Radicals; Hypoxanthine; Leupeptins; Lung; Matrix Metalloproteinase 2; Muscle, Smooth; Muscle, Smooth, Vascular; Oligopeptides; Oxygen; Pepstatins; Phenylmethylsulfonyl Fluoride; Superoxides; Tissue Inhibitor of Metalloproteinase-2; Trypsin Inhibitor, Bowman-Birk Soybean

2002
Kinetic studies of serine protease inhibitors in simple and rapid 'active barrier' model systems - Diffusion through an inhibitor barrier.
    Analytical biochemistry, 2018, 04-01, Volume: 546

    Topics: Antipain; Diffusion; Dose-Response Relationship, Drug; Gelatin; Kinetics; Leupeptins; Models, Biological; Oligopeptides; Particle Size; Peptide Hydrolases; Serine Proteinase Inhibitors; Spectrophotometry; Structure-Activity Relationship; Surface Properties

2018