Page last updated: 2024-09-03

leukotriene b5 and leukotriene b4

leukotriene b5 has been researched along with leukotriene b4 in 55 studies

Compound Research Comparison

Studies
(leukotriene b5)
Trials
(leukotriene b5)
Recent Studies (post-2010)
(leukotriene b5)
Studies
(leukotriene b4)
Trials
(leukotriene b4)
Recent Studies (post-2010) (leukotriene b4)
571185,886232717

Protein Interaction Comparison

ProteinTaxonomyleukotriene b5 (IC50)leukotriene b4 (IC50)
Leukotriene B4 receptor 1Homo sapiens (human)0.0019

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199019 (34.55)18.7374
1990's17 (30.91)18.2507
2000's11 (20.00)29.6817
2010's8 (14.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamazaki, T; Nakamura, N; Sawazaki, S; Urakaze, M; Yamazaki, K; Yano, S1
Hiwatashi, N; Ikehata, A; Ito, K; Kayaba, Y; Kinouchi, Y; Kumagai, Y; Toyota, T; Yamazaki, H1
Andazola, JJ; Chiono, M; Herman, CA; Torres, OA; Underwood, JA1
Belluzzi, A; Daneshmend, TK; Everitt, SJ; Hawkey, CJ; Hawthorne, AB; Holmes, GK; Malkinson, C; Shaheen, MZ; Willars, JE1
Barth, J; Chang, A; Happle, R; van de Kerkhof, PC; Wozel, G2
Fahrer, C; Fischer, S; von Schacky, C1
Betts, WH; Cleland, LG; Gibson, RA; Hawkes, JS; James, MJ1
Chang, KJ; Saito, H; Tamura, Y; Tatsuno, I; Yoshida, S1
Goetzl, EJ; Kragballe, K; Voorhees, JJ1
Barrow, SE; Pettitt, TR; Rowley, AF1
Kojima, T; Okamoto, S; Tamura, Y; Tanabe, E; Terano, T; Yoshida, S1
Chang, KJ; Saito, H; Tamura, Y; Tatsuno, I; Watanabe, K; Yoshida, S1
Fogh, K; Kragballe, K1
Hughes, RA; Lee, T; Taylor, WA1
Breeze, RG; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Straub, KM; Taylor, SM1
Seya, A; Tamura, Y; Terano, T; Yoshida, S1
Barden, A; Beilin, LJ; Codde, JP; Croft, KD; Vandongen, R1
Morrison, AR; Prescott, SM; Zimmerman, GA1
Evans, JF; Fitzsimmons, BJ; Ford-Hutchinson, AW; Leblanc, Y; Léveillé, C; Nathaniel, DJ1
Austen, KF; Corey, EJ; Drazen, JM; Israel, E; Lee, TH; Leitch, AG; Lewis, RA; Ravalese, J; Robinson, DR1
Dondero-Zahn, C; Nytko, D; Pickett, WC; Ramesha, C1
Charleson, S; Evans, J; Fitzsimmons, BJ; Frenette, R; Hamel, P; Leblanc, Y; Leger, S; Léveillé, C; Nathaniel, D; Zamboni, R1
Blake, VA; Chernov-Rogan, T; Goetzl, EJ; Gold, WM; Payan, DG; Pickett, WC; Valone, FH; Wong, MY1
Charleson, S; Dupuis, P; Evans, JF; Fitzsimmons, BJ; Ford-Hutchinson, AW; Leblanc, Y; Leveillé, C; Zamboni, RJ1
Goetzl, EJ; Goldman, DW; Pickett, WC1
Austen, KF; Corey, EJ; Lee, TH; Lewis, RA; Menica-Huerta, JM; Shih, C1
Moncada, S; Salmon, JA; Terano, T1
Dola, T; Tou, JS1
Kitamura, S; Kobayashi, J; Yokoyama, S1
Chilton, FH; Fonteh, AN; Hubbard, WC; Patel, M; Triggiani, M1
Hamazaki, T; Ibuki, F; Kobayashi, M; Nakamura, N; Taki, H; Yamazaki, K; Yazawa, K1
Gu, JY; Hung, P; Ikeda, I; Kaku, S; Ohkura, K; Sugano, M; Yamada, K; Yazawa, K; Yunoki, S1
Christensen, JH; Løssl, K; Schmidt, EB; Skou, HA1
Kitamura, S; Kobayashi, J; Saku, N1
Badr, KF; Fukunaga, M; Imai, E; Kaneda, Y; Montero, A; Munger, KA; Uda, S; Valdivielso, JM; Yura, T1
Matsuo, N; Mori, M; Ozeki, M; Shoji, K; Sugano, M; Ueyama, T; Yamada, K; Yamashita, K; Yunoki, S1
Gu, JY; Hung, P; Ikeda, I; Kaku, S; Ohkura, K; Sugano, M; Tachibana, H; Yamada, K; Yazawa, K; Yunoki, S1
Engström, K; Saldeen, T; Wallin, R1
Avois, L; Decosterd, LA; Hug, C; Panchaud, A; Pilet, M; Roulet, M; Saugy, M1
Hall, JA; Henry, LR; Jewell, DE; Jha, S; Skinner, MM; Wander, RC1
Boulat, O; Buclin, T; Decosterd, LA; Hug, C; Kernen, Y; Panchaud, A; Pilet, M; Roulet, M; Sauty, A1
Fly, AD; Ionescu, AA; Lindley, MR; Mickleborough, TD1
Cherian, G; Hall, JA; Jha, S; Skinner, MM1
Bessard, J; Lagarde, M; Laville, M; Molière, P; Stanke-Labesque, F; Véricel, E1
Bachi, AL; Carneiro, CR; Correa, M; Jasiulionis, MG; Kim, FJ; Lopes, JD; Nonogaki, S1
Moreno, JJ1
Chew, BP; Hayek, MG; Park, HJ; Park, JS; Reinhart, GA1
Aardestrup, IV; Christensen, JH; Maaløe, T; Schmidt, EB; Svensson, M1
Kang, WM; Ma, ZQ; Wang, J; Yu, JC1
Bauer, JE; Hannah, SS; Waldron, MK1
Aardestrup, I; Gammelmark, A; Madsen, T; Nielsen, MS; Obel, T; Schmidt, EB1
Calder, PC; Lindorff-Larsen, K; Lundbye-Christensen, S; Rasmussen, HH; Schmidt, EB; Sorensen, LS; Thorlacius-Ussing, O1
Araujo, P; Chen, L; Espe, M; He, J; Holen, E1
Barden, AE; Beilin, LJ; Burke, V; Irish, AB; Mori, TA; Puddey, IB; Shinde, S; Watts, GF1

Trials

11 trial(s) available for leukotriene b5 and leukotriene b4

ArticleYear
Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial.
    Gut, 1992, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Olive Oil; Plant Oils; Prednisolone; Prospective Studies; Remission Induction; Sulfasalazine

1992
The effect of n-3 fatty acids on leukotriene formation from neutrophils in patients on hemodialysis.
    Lipids, 1999, Volume: 34 Suppl

    Topics: Dietary Fats, Unsaturated; Dietary Supplements; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Kidney Failure, Chronic; Leukotriene B4; Leukotrienes; Male; Middle Aged; Neutrophils; Olive Oil; Plant Oils; Reference Values; Renal Dialysis

1999
Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids.
    Prostaglandins, leukotrienes, and essential fatty acids, 2001, Volume: 64, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Drug Interactions; Eicosanoids; Eicosapentaenoic Acid; Fish Oils; Humans; Leukotriene B4; Middle Aged; Thromboxane B2

2001
Biological effects of a dietary omega-3 polyunsaturated fatty acids supplementation in cystic fibrosis patients: a randomized, crossover placebo-controlled trial.
    Clinical nutrition (Edinburgh, Scotland), 2006, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Cell Membrane; Chemotaxis, Leukocyte; Child; Cross-Over Studies; Cystic Fibrosis; Dietary Supplements; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Interleukin-8; Leukotriene B4; Neutrophils; Placebos; Receptors, Interleukin

2006
Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma.
    Chest, 2006, Volume: 129, Issue:1

    Topics: Adult; Asthma; Bronchoconstriction; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Eicosapentaenoic Acid; Exercise Test; Female; Fish Oils; Follow-Up Studies; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene B4; Male; Sputum; Treatment Outcome

2006
Effect of dietary supplementation with increasing doses of docosahexaenoic acid on neutrophil lipid composition and leukotriene production in human healthy volunteers.
    The British journal of nutrition, 2008, Volume: 100, Issue:4

    Topics: Aged; Arachidonic Acid; Cells, Cultured; Dietary Fats; Dietary Supplements; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Humans; Leukotriene B4; Leukotrienes; Lipids; Male; Middle Aged; Neutrophils; Statistics, Nonparametric; Tandem Mass Spectrometry

2008
The effect of n-3 polyunsaturated fatty acids on leukotriene B₄ and leukotriene B₅ production from stimulated neutrophil granulocytes in patients with chronic kidney disease.
    Prostaglandins, leukotrienes, and essential fatty acids, 2011, Volume: 85, Issue:1

    Topics: Dietary Supplements; Double-Blind Method; Down-Regulation; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Female; Fish Oils; Granulocytes; Humans; Kidney; Leukotriene B4; Male; Middle Aged; Neutrophil Activation; Neutrophils; Patient Dropouts; Renal Insufficiency, Chronic; Severity of Illness Index; Up-Regulation

2011
Superiority of a fish oil-enriched emulsion to medium-chain triacylglycerols/long-chain triacylglycerols in gastrointestinal surgery patients: a randomized clinical trial.
    Nutrition (Burbank, Los Angeles County, Calif.), 2012, Volume: 28, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bilirubin; Cross Infection; Dietary Fats; Eicosapentaenoic Acid; Fat Emulsions, Intravenous; Fatty Acids, Omega-3; Female; Fish Oils; Gastrointestinal Diseases; Humans; Immunity; Inflammation; Inflammation Mediators; Leukotriene B4; Liver; Male; Middle Aged; NF-kappa B; Parenteral Nutrition; Partial Thromboplastin Time; Postoperative Complications; Systemic Inflammatory Response Syndrome; Triglycerides; Tumor Necrosis Factor-alpha

2012
The effect of low-dose marine n-3 fatty acids on the biosynthesis of pro-inflammatory 5-lipoxygenase pathway metabolites in overweight subjects: a randomized controlled trial.
    Prostaglandins, leukotrienes, and essential fatty acids, 2012, Volume: 87, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cardiotonic Agents; Cell Membrane; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Middle Aged; Multivariate Analysis; Neutrophils; Obesity, Abdominal; Overweight; Treatment Outcome

2012
Effects of perioperative supplementation with omega-3 fatty acids on leukotriene B₄ and leukotriene B₅ production by stimulated neutrophils in patients with colorectal cancer: a randomized, placebo-controlled intervention trial.
    Nutrients, 2014, Sep-29, Volume: 6, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Eicosapentaenoic Acid; Elective Surgical Procedures; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Humans; Leukotriene B4; Male; Middle Aged; Neutrophils; Postoperative Complications; Postoperative Period; Preoperative Period; Prospective Studies; Treatment Outcome

2014
The effect of n-3 fatty acids and coenzyme Q10 supplementation on neutrophil leukotrienes, mediators of inflammation resolution and myeloperoxidase in chronic kidney disease.
    Prostaglandins & other lipid mediators, 2018, Volume: 136

    Topics: Adult; Aged; Dietary Supplements; Double-Blind Method; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Leukotriene B4; Male; Middle Aged; Neutrophils; Peroxidase; Renal Insufficiency, Chronic; Ubiquinone

2018

Other Studies

44 other study(ies) available for leukotriene b5 and leukotriene b4

ArticleYear
Intravenous infusion of trieicosapentaenoyl-glycerol and LTB4 and LTB5 production by leukocytes of rabbits.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 2

    Topics: Animals; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Emulsions; Glycerol; Infusions, Intravenous; Leukotriene B4; Lipids; Male; Neutrophils; Osmolar Concentration; Rabbits; Soybean Oil; Time Factors

1992
Effect of intravenously infused eicosapentaenoic acid on the leukotriene generation in patients with active Crohn's disease.
    The American journal of clinical nutrition, 1992, Volume: 56, Issue:5

    Topics: Adult; Crohn Disease; Eicosapentaenoic Acid; Fat Emulsions, Intravenous; Female; Fish Oils; Humans; Infusions, Intravenous; Leukotriene B4; Leukotrienes; Male; Neutrophils

1992
Leukotriene B4 and leukotriene B5 have binding sites on lung membranes and cause contraction of bullfrog lung.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3

    Topics: Animals; Binding Sites; Eicosapentaenoic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Leukotriene B4; Lung; Male; Muscle Contraction; Rana catesbeiana

1992
The effect of leukotriene B5 on the accumulation of polymorphonuclear leukocytes (PMN) in normal skin and LTB4-stimulated human skin.
    Agents and actions, 1991, Volume: 32, Issue:1-2

    Topics: Eicosapentaenoic Acid; Humans; Leukotriene B4; Neutrophils; Skin

1991
Catabolism of leukotriene B5 in humans.
    Journal of lipid research, 1990, Volume: 31, Issue:10

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Cod Liver Oil; Eicosapentaenoic Acid; Humans; Ionophores; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Neutrophils; Spectrophotometry, Ultraviolet

1990
Effect of dietary oils on the production of n-3 and n-6 metabolites of leukocyte 5-lipoxygenase in five rat strains.
    Biochimica et biophysica acta, 1990, Apr-17, Volume: 1043, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; In Vitro Techniques; Leukotriene B4; Linseed Oil; Oils; Olive Oil; Peritoneal Cavity; Phospholipids; Plant Oils; Rats; Rats, Inbred Strains; Sunflower Oil

1990
Comparison of the effect between leukotriene B4 and leukotriene B5 on the induction of interleukin 1-like activity and calcium mobilizing activity in human blood monocytes.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Calcium; Cytosol; Eicosapentaenoic Acid; Humans; Interleukin-1; Leukotriene B4; Monocytes

1990
Effect of leukotriene B5 on the accumulation of polymorphonuclear leukocytes in unstimulated and leukotriene B4-stimulated human skin.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1990, Volume: 3, Issue:1

    Topics: Adult; Chemotaxis, Leukocyte; Eicosapentaenoic Acid; Female; Humans; Leukotriene B4; Male; Neutrophils; Skin

1990
Inhibition by leukotriene B5 of leukotriene B4-induced activation of human keratinocytes and neutrophils.
    The Journal of investigative dermatology, 1987, Volume: 88, Issue:5

    Topics: Chemotaxis, Leukocyte; DNA; Eicosapentaenoic Acid; Epidermal Cells; Epidermis; Humans; Keratins; Leukotriene B4; Lymphocyte Activation; Neutrophils

1987
Synthesis of leukotriene B and other conjugated triene lipoxygenase products by blood cells of the rainbow trout, Salmo gairdneri.
    Biochimica et biophysica acta, 1989, May-15, Volume: 1003, Issue:1

    Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; Fatty Acids; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Leukocytes; Leukotriene B4; Salmonidae; Trout

1989
Effect of highly purified eicosapentaenoic acid on psoriasis.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:1

    Topics: Adult; Aged; Chronic Disease; Eicosapentaenoic Acid; Female; Humans; Leukotriene B4; Male; Middle Aged; Neutrophils; Psoriasis

1989
Comparison of the effect of lipoxygenase metabolites of arachidonic acid and eicosapentaenoic acid on human natural killer cell cytotoxicity.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 38, Issue:2

    Topics: Arachidonic Acids; Cytotoxicity, Immunologic; Eicosapentaenoic Acid; Humans; Killer Cells, Natural; Leukotriene B4; Lipoxygenase; Tumor Cells, Cultured

1989
A low-fat diet supplemented with dietary fish oil (Max-EPA) results in improvement of psoriasis and in formation of leukotriene B5.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Dietary Fats; Docosahexaenoic Acids; Drug Combinations; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Female; Fish Oils; Humans; Leukotriene B4; Male; Middle Aged; Neutrophils; Psoriasis

1989
Lack of effect of fish oil-enriched diet on experimental allergic neuritis in Lewis rats.
    Journal of neuroimmunology, 1988, Volume: 17, Issue:3

    Topics: Animals; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; Leukocyte Count; Leukotriene B4; Neuritis, Autoimmune, Experimental; Neutrophils; Rats; Rats, Inbred Lew; T-Lymphocytes

1988
Production of lipoxygenase metabolites of eicosapentaenoic acid by bovine alveolar macrophages in vitro.
    Inflammation, 1988, Volume: 12, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Cattle; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; In Vitro Techniques; Leukotriene B4; Lipoxygenase; Macrophages; Mass Spectrometry; Pulmonary Alveoli

1988
Comparative effect of leukotriene B4 and leukotriene B5 on calcium mobilization in human neutrophils.
    Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 34, Issue:1

    Topics: Calcium; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Fluorescence; Humans; Leukotriene B4; Neutrophils

1988
Effect of dietary fish oils on the formation of leukotriene B4 and B5, thromboxane and platelet activating factor by rat leukocytes.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diet; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Male; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes

1988
The effects of a diet rich in fish oil on human neutrophils: identification of leukotriene B5 as a metabolite.
    Prostaglandins, 1985, Volume: 30, Issue:2

    Topics: Arachidonic Acid; Arachidonic Acids; Cell Adhesion; Cell Aggregation; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; Humans; Leukotriene B4; Neutrophils; Prostaglandin-Endoperoxide Synthases

1985
Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase.
    Biochemical and biophysical research communications, 1985, Sep-16, Volume: 131, Issue:2

    Topics: Animals; Arachidonic Acids; Eicosapentaenoic Acid; Epoxide Hydrolases; Humans; Kinetics; Leukotriene A4; Leukotriene B4; Neutrophils; Rats

1985
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Apr-01, Volume: 136, Issue:7

    Topics: Anaphylaxis; Animals; Cattle; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Indomethacin; Leukotriene B4; Lung; Male; Muscle Contraction; Pyrilamine; Thromboxane B2

1986
The effect of endogenous eicosapentaenoic acid on PMN leukotriene and PAF biosynthesis.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: Animals; Diet; Eicosapentaenoic Acid; Fish Oils; Leukotriene B4; Neutrophils; Platelet Activating Factor; Rats

1986
Neutrophil LTA4 hydrolases and leukotriene B4 receptors: effects of leukotriene epoxides and their enzymatic products.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: Animals; Arachidonic Acids; Cell Membrane; Eicosapentaenoic Acid; Epoxide Hydrolases; Humans; Hydrolysis; Leukotriene A4; Leukotriene B4; Neutrophils; Rats; Receptors, Immunologic; Receptors, Leukotriene B4; Time Factors

1986
Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid.
    Journal of clinical immunology, 1986, Volume: 6, Issue:5

    Topics: Administration, Oral; Asthma; Chemotaxis, Leukocyte; Dinoprostone; Eicosapentaenoic Acid; Fatty Acids; Humans; Leukotriene B4; Lymphocyte Activation; Neutrophils; Prostaglandins E; T-Lymphocytes

1986
Leukotriene B3, leukotriene B4 and leukotriene B5; binding to leukotriene B4 receptors on rat and human leukocyte membranes.
    Prostaglandins, 1986, Volume: 32, Issue:4

    Topics: Animals; Cell Aggregation; Chemotaxis, Leukocyte; Eicosapentaenoic Acid; Humans; Kinetics; Leukocytes; Leukotriene B4; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene B4

1986
Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid.
    Biochemical and biophysical research communications, 1983, Nov-30, Volume: 117, Issue:1

    Topics: Chemotaxis, Leukocyte; Cytoplasmic Granules; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Humans; Isomerism; Kinetics; Leukotriene B4; Lysosomes; Neutrophils; Structure-Activity Relationship

1983
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
    The Journal of biological chemistry, 1984, Feb-25, Volume: 259, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Biological Assay; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; Humans; Leukotriene B4; Lipoxygenase; Neutrophils; Stereoisomerism; Structure-Activity Relationship

1984
Biosynthesis and biological activity of leukotriene B5.
    Prostaglandins, 1984, Volume: 27, Issue:2

    Topics: Animals; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Cytochalasin B; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Glucuronidase; Humans; Leukotriene B4; Lysosomes; Mice; Neutrophils; Rabbits; Rats

1984
Leukotriene B4 stimulation of an early elevation of phosphatidic acid mass in human neutrophils.
    Lipids, 1995, Volume: 30, Issue:5

    Topics: Cytochalasin B; Diglycerides; Eicosapentaenoic Acid; Enzyme Activation; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Phosphatidic Acids; Phospholipase D; Signal Transduction

1995
Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 52, Issue:4

    Topics: Animals; Arachidonic Acid; Eicosapentaenoic Acid; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar

1995
Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production. Influence of duration and dosage.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:1

    Topics: Adult; Dietary Fats; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Fish Oils; Humans; Kinetics; Leukotriene B4; Lipids; Male; Neutrophils; Phospholipids; Platelet Activating Factor; Reference Values; Time Factors

1993
Intravenous infusion of tridocosahexaenoyl-glycerol emulsion into rabbits. Effects on leukotriene B4/5 production and fatty acid composition of plasma and leukocytes.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:3

    Topics: Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Emulsions; Fatty Acids; Glycerol; Infusions, Intravenous; Leukotriene B4; Lipids; Male; Neutrophils; Rabbits; Soybean Oil

1993
Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of Sprague-Dawley rats.
    Bioscience, biotechnology, and biochemistry, 1999, Volume: 63, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fish Oils; Immunity; Immunoglobulin G; Immunoglobulin M; Leukotriene B4; Lymphocytes; Male; Rats; Rats, Sprague-Dawley; Safflower Oil; Spleen; T-Lymphocytes; Thiobarbituric Acid Reactive Substances

1999
Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages activated by silica.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; L-Lactate Dehydrogenase; Leukotriene B4; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Silicon Dioxide

1999
Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-09, Volume: 96, Issue:23

    Topics: Animals; Arachidonate 15-Lipoxygenase; Eicosapentaenoic Acid; Genetic Therapy; Glomerular Filtration Rate; Glomerulonephritis; Green Fluorescent Proteins; Humans; Immunohistochemistry; Kidney; Leukotriene B4; Luminescent Proteins; Male; Rats; Rats, Sprague-Dawley; Transfection

1999
Inhibition by dietary tea polyphenols of chemical mediator release from rat peritoneal exudate cells.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:7

    Topics: Animals; Cells, Cultured; Dietary Fats; Dietary Supplements; Eating; Eicosapentaenoic Acid; Fatty Acids; Flavonoids; Growth; Histamine Release; Leukotriene B4; Liver; Male; Organ Size; Peritoneum; Phenols; Phospholipids; Polymers; Polyphenols; Rats; Rats, Wistar; Tea

2000
Dietary effects of eicosapentaenoic and docosahexaenoic acid esters on lipid metabolism and immune parameters in Sprague-Dawley rats.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:12

    Topics: Animals; Calcimycin; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Exudates and Transudates; Fatty Acids; Immunoglobulins; Ionophores; Leukotriene B4; Lipid Metabolism; Lipids; Liver; Male; Phospholipids; Rats; Rats, Sprague-Dawley

2000
A validated liquid chromatography-mass spectrometry method for the determination of leukotrienes B4 and B5 produced by stimulated human polymorphonuclear leukocytes.
    Analytical biochemistry, 2005, Jun-01, Volume: 341, Issue:1

    Topics: Calibration; Chromatography, Liquid; Eicosapentaenoic Acid; Humans; Leukotriene B4; Neutrophil Activation; Neutrophils; Spectrometry, Mass, Electrospray Ionization; Temperature; Thermodynamics

2005
Dietary (n-3) fatty acids alter plasma fatty acids and leukotriene B synthesis by stimulated neutrophils from healthy geriatric Beagles.
    Prostaglandins, leukotrienes, and essential fatty acids, 2005, Volume: 73, Issue:5

    Topics: Aging; Animals; Corn Oil; Diet; Dogs; Eating; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Female; Leukotriene B4; Neutrophils

2005
Maternal dietary n-3 fatty acids alter immune cell fatty acid composition and leukotriene production in growing chicks.
    Prostaglandins, leukotrienes, and essential fatty acids, 2007, Volume: 76, Issue:1

    Topics: Animals; Arachidonic Acid; Bursa of Fabricius; Chickens; Dietary Fats; Docosahexaenoic Acids; Egg Yolk; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Leukotriene B4; Leukotrienes; Spleen

2007
Leukotriene B4 creates a favorable microenvironment for murine melanoma growth.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:9

    Topics: Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Carrageenan; Cell Growth Processes; Cell Line, Tumor; Disease Progression; Eicosapentaenoic Acid; Histocytochemistry; Indomethacin; Inflammation; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Melanoma; Mice; Prostaglandin-Endoperoxide Synthases

2009
Differential effects of arachidonic and eicosapentaenoic Acid-derived eicosanoids on polymorphonuclear transmigration across endothelial cell cultures.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Albumins; Alprostadil; Arachidonic Acid; Capillary Permeability; Cell Adhesion; Cell Line; Chemotaxis, Leukocyte; Dinoprostone; Eicosanoids; Eicosapentaenoic Acid; Endothelial Cells; Endothelium, Vascular; Evans Blue; Humans; Leukotriene B4; Neutrophils

2009
Dietary fish oil and flaxseed oil suppress inflammation and immunity in cats.
    Veterinary immunology and immunopathology, 2011, Jun-15, Volume: 141, Issue:3-4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cat Diseases; Cats; Diet; Dietary Fats, Unsaturated; Eicosapentaenoic Acid; Female; Fish Oils; Immunosuppressive Agents; Inflammation; Leukotriene B4; Linseed Oil; Lymphocyte Subsets; Pokeweed Mitogens; Skin

2011
Plasma phospholipid fatty acid and ex vivo neutrophil responses are differentially altered in dogs fed fish- and linseed-oil containing diets at the same n-6:n-3 fatty acid ratio.
    Lipids, 2012, Volume: 47, Issue:4

    Topics: Animals; Cell Membrane; Cells, Cultured; Dietary Fats; Docosahexaenoic Acids; Dogs; Eicosapentaenoic Acid; Fats; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Fish Oils; Leukotriene B4; Linseed Oil; Lipid Metabolism; Male; Neutrophils; Phospholipids; Safflower Oil; Superoxides

2012
Combining eicosapentaenoic acid, decosahexaenoic acid and arachidonic acid, using a fully crossed design, affect gene expression and eicosanoid secretion in salmon head kidney cells in vitro.
    Fish & shellfish immunology, 2015, Volume: 45, Issue:2

    Topics: Alprostadil; Animals; Arachidonic Acid; bcl-X Protein; CD36 Antigens; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Gene Expression Regulation; Head Kidney; Intramolecular Oxidoreductases; Leukocytes; Leukotriene B4; Male; Salmon; Tumor Necrosis Factor-alpha

2015