Compounds > leukotriene b5
Page last updated: 2024-09-03

leukotriene b5 and indomethacin

leukotriene b5 has been researched along with indomethacin in 2 studies

Compound Research Comparison

Studies
(leukotriene b5)		Trials
(leukotriene b5)		Recent Studies (post-2010)
(leukotriene b5)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
5711829,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyleukotriene b5 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Austen, KF; Corey, EJ; Drazen, JM; Israel, E; Lee, TH; Leitch, AG; Lewis, RA; Ravalese, J; Robinson, DR1
Bachi, AL; Carneiro, CR; Correa, M; Jasiulionis, MG; Kim, FJ; Lopes, JD; Nonogaki, S1

Other Studies

2 other study(ies) available for leukotriene b5 and indomethacin

ArticleYear
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Apr-01, Volume: 136, Issue:7

    Topics: Anaphylaxis; Animals; Cattle; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Indomethacin; Leukotriene B4; Lung; Male; Muscle Contraction; Pyrilamine; Thromboxane B2

1986
Leukotriene B4 creates a favorable microenvironment for murine melanoma growth.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:9

    Topics: Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Carrageenan; Cell Growth Processes; Cell Line, Tumor; Disease Progression; Eicosapentaenoic Acid; Histocytochemistry; Indomethacin; Inflammation; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Melanoma; Mice; Prostaglandin-Endoperoxide Synthases

2009