Page last updated: 2024-09-03

leukotriene b5 and arachidonic acid

leukotriene b5 has been researched along with arachidonic acid in 11 studies

Compound Research Comparison

Studies
(leukotriene b5)
Trials
(leukotriene b5)
Recent Studies (post-2010)
(leukotriene b5)
Studies
(arachidonic acid)
Trials
(arachidonic acid)
Recent Studies (post-2010) (arachidonic acid)
5711819,2954863,040

Protein Interaction Comparison

ProteinTaxonomyleukotriene b5 (IC50)arachidonic acid (IC50)
60 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
Fatty acid-binding protein, adipocyteHomo sapiens (human)2.75
10 kDa heat shock protein, mitochondrialHomo sapiens (human)4.5
60 kDa chaperonin Escherichia coli7.3
10 kDa chaperonin Escherichia coli7.3
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.0715
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.6026

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Betts, WH; Cleland, LG; Gibson, RA; Hawkes, JS; James, MJ1
Breeze, RG; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Straub, KM; Taylor, SM1
Barden, A; Beilin, LJ; Codde, JP; Croft, KD; Vandongen, R1
Morrison, AR; Prescott, SM; Zimmerman, GA1
Austen, KF; Corey, EJ; Lee, TH; Lewis, RA; Menica-Huerta, JM; Shih, C1
Kitamura, S; Kobayashi, J; Yokoyama, S1
Kitamura, S; Kobayashi, J; Saku, N1
Cherian, G; Hall, JA; Jha, S; Skinner, MM1
Bessard, J; Lagarde, M; Laville, M; Molière, P; Stanke-Labesque, F; Véricel, E1
Moreno, JJ1
Araujo, P; Chen, L; Espe, M; He, J; Holen, E1

Trials

1 trial(s) available for leukotriene b5 and arachidonic acid

ArticleYear
Effect of dietary supplementation with increasing doses of docosahexaenoic acid on neutrophil lipid composition and leukotriene production in human healthy volunteers.
    The British journal of nutrition, 2008, Volume: 100, Issue:4

    Topics: Aged; Arachidonic Acid; Cells, Cultured; Dietary Fats; Dietary Supplements; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Humans; Leukotriene B4; Leukotrienes; Lipids; Male; Middle Aged; Neutrophils; Statistics, Nonparametric; Tandem Mass Spectrometry

2008

Other Studies

10 other study(ies) available for leukotriene b5 and arachidonic acid

ArticleYear
Effect of dietary oils on the production of n-3 and n-6 metabolites of leukocyte 5-lipoxygenase in five rat strains.
    Biochimica et biophysica acta, 1990, Apr-17, Volume: 1043, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; In Vitro Techniques; Leukotriene B4; Linseed Oil; Oils; Olive Oil; Peritoneal Cavity; Phospholipids; Plant Oils; Rats; Rats, Inbred Strains; Sunflower Oil

1990
Production of lipoxygenase metabolites of eicosapentaenoic acid by bovine alveolar macrophages in vitro.
    Inflammation, 1988, Volume: 12, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Cattle; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; In Vitro Techniques; Leukotriene B4; Lipoxygenase; Macrophages; Mass Spectrometry; Pulmonary Alveoli

1988
Effect of dietary fish oils on the formation of leukotriene B4 and B5, thromboxane and platelet activating factor by rat leukocytes.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diet; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Male; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes

1988
The effects of a diet rich in fish oil on human neutrophils: identification of leukotriene B5 as a metabolite.
    Prostaglandins, 1985, Volume: 30, Issue:2

    Topics: Arachidonic Acid; Arachidonic Acids; Cell Adhesion; Cell Aggregation; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; Humans; Leukotriene B4; Neutrophils; Prostaglandin-Endoperoxide Synthases

1985
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
    The Journal of biological chemistry, 1984, Feb-25, Volume: 259, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Biological Assay; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; Humans; Leukotriene B4; Lipoxygenase; Neutrophils; Stereoisomerism; Structure-Activity Relationship

1984
Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 52, Issue:4

    Topics: Animals; Arachidonic Acid; Eicosapentaenoic Acid; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar

1995
Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages activated by silica.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; L-Lactate Dehydrogenase; Leukotriene B4; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Silicon Dioxide

1999
Maternal dietary n-3 fatty acids alter immune cell fatty acid composition and leukotriene production in growing chicks.
    Prostaglandins, leukotrienes, and essential fatty acids, 2007, Volume: 76, Issue:1

    Topics: Animals; Arachidonic Acid; Bursa of Fabricius; Chickens; Dietary Fats; Docosahexaenoic Acids; Egg Yolk; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Leukotriene B4; Leukotrienes; Spleen

2007
Differential effects of arachidonic and eicosapentaenoic Acid-derived eicosanoids on polymorphonuclear transmigration across endothelial cell cultures.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Albumins; Alprostadil; Arachidonic Acid; Capillary Permeability; Cell Adhesion; Cell Line; Chemotaxis, Leukocyte; Dinoprostone; Eicosanoids; Eicosapentaenoic Acid; Endothelial Cells; Endothelium, Vascular; Evans Blue; Humans; Leukotriene B4; Neutrophils

2009
Combining eicosapentaenoic acid, decosahexaenoic acid and arachidonic acid, using a fully crossed design, affect gene expression and eicosanoid secretion in salmon head kidney cells in vitro.
    Fish & shellfish immunology, 2015, Volume: 45, Issue:2

    Topics: Alprostadil; Animals; Arachidonic Acid; bcl-X Protein; CD36 Antigens; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Gene Expression Regulation; Head Kidney; Intramolecular Oxidoreductases; Leukocytes; Leukotriene B4; Male; Salmon; Tumor Necrosis Factor-alpha

2015