leukotriene-a4 and linsidomine

leukotriene-a4 has been researched along with linsidomine* in 1 studies

Other Studies

1 other study(ies) available for leukotriene-a4 and linsidomine

Article	Year
[Effect of SIN-1 on the synthesis of leukotrienes in human polymorphonuclear cells]. Pathologie-biologie, 1987, Volume: 35, Issue:2 Pt 2 Leukotriene (LT) synthesis triggered with ionophore A23187 or inflammatory stimuli (PAF, fMLP) in human polymorphonuclear leukocytes (PMNL) was markedly decreased by SIN-1, an active metabolite of molsidomine. This inhibition occurred in the absence or in the presence of exogenous arachidonic acid (AA). These results suggest that SIN-1 inhibited both the release of AA from membrane phospholipids and the 5-lipoxygenase activity in human PMNL. Molsidomine was without any effect on LT formation. Topics: Arachidonic Acids; Humans; Leukotriene A4; Leukotriene B4; Molsidomine; Neutrophils	1987

Article

Year

[Effect of SIN-1 on the synthesis of leukotrienes in human polymorphonuclear cells].

Pathologie-biologie, 1987, Volume: 35, Issue:2 Pt 2

Leukotriene (LT) synthesis triggered with ionophore A23187 or inflammatory stimuli (PAF, fMLP) in human polymorphonuclear leukocytes (PMNL) was markedly decreased by SIN-1, an active metabolite of molsidomine. This inhibition occurred in the absence or in the presence of exogenous arachidonic acid (AA). These results suggest that SIN-1 inhibited both the release of AA from membrane phospholipids and the 5-lipoxygenase activity in human PMNL. Molsidomine was without any effect on LT formation.

Topics: Arachidonic Acids; Humans; Leukotriene A4; Leukotriene B4; Molsidomine; Neutrophils

1987