leuconoxine and phosphoric-acid

leuconoxine has been researched along with phosphoric-acid* in 1 studies

Other Studies

1 other study(ies) available for leuconoxine and phosphoric-acid

ArticleYear
Asymmetric total synthesis of (-)-leuconoxine via chiral phosphoric acid catalyzed desymmetrization of a prochiral diester.
    Organic letters, 2015, Jan-02, Volume: 17, Issue:1

    The asymmetric total synthesis of (-)-leuconoxine has been achieved. The desymmetrization of a prochiral diester using a chiral phosphoric acid catalyst produced a highly enantioenriched lactam with excellent yield. The ring construction featuring an intramolecular N-acyliminium cyclization and the one-step pyrrolidone formation using Bestmann's ylide was successfully accomplished.

    Topics: Apocynaceae; Catalysis; Cyclization; Indole Alkaloids; Lactams; Molecular Structure; Phosphoric Acids; Pyrrolidinones; Stereoisomerism

2015