leuconoxine has been researched along with phosphoric-acid* in 1 studies
1 other study(ies) available for leuconoxine and phosphoric-acid
Article | Year |
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Asymmetric total synthesis of (-)-leuconoxine via chiral phosphoric acid catalyzed desymmetrization of a prochiral diester.
The asymmetric total synthesis of (-)-leuconoxine has been achieved. The desymmetrization of a prochiral diester using a chiral phosphoric acid catalyst produced a highly enantioenriched lactam with excellent yield. The ring construction featuring an intramolecular N-acyliminium cyclization and the one-step pyrrolidone formation using Bestmann's ylide was successfully accomplished. Topics: Apocynaceae; Catalysis; Cyclization; Indole Alkaloids; Lactams; Molecular Structure; Phosphoric Acids; Pyrrolidinones; Stereoisomerism | 2015 |