Page last updated: 2024-09-02

leucinol and etoposide

leucinol has been researched along with etoposide in 2 studies

Compound Research Comparison

Studies (leucinol)	Trials (leucinol)	Recent Studies (post-2010) (leucinol)	Studies (etoposide)	Trials (etoposide)	Recent Studies (post-2010) (etoposide)
17	0	9	18,306	3,693	4,900

Protein Interaction Comparison

Protein	Taxonomy	etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	Homo sapiens (human)	1.153
nuclear receptor coactivator 3 isoform a	Homo sapiens (human)	1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	3.187
Caspase-3	Homo sapiens (human)	1
DNA topoisomerase 2-beta	Homo sapiens (human)	0.4299
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	4.18

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ann, J; Cho, D; Kim, JH; Kim, S; Kim, SE; Kim, WK; Lee, J; Lee, S; Yoon, I; Yoon, S; Zuo, D	1
Ann, J; Byun, WS; Kim, C; Kim, JH; Kim, S; Kim, SE; Lee, J; Lee, S; Tran, PT; Yoon, I; Yoon, S	1

Other Studies

2 other study(ies) available for leucinol and etoposide

Article	Year
Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14 Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Leucine; Leucine-tRNA Ligase; Mechanistic Target of Rapamycin Complex 1; Molecular Structure; Structure-Activity Relationship	2018
Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1). Bioorganic & medicinal chemistry, 2019, 03-15, Volume: 27, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; HEK293 Cells; Humans; Leucine; Leucine-tRNA Ligase; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Signal Transduction; Structure-Activity Relationship	2019

Article

Year

Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors.

Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Leucine; Leucine-tRNA Ligase; Mechanistic Target of Rapamycin Complex 1; Molecular Structure; Structure-Activity Relationship

2018

Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1).

Bioorganic & medicinal chemistry, 2019, 03-15, Volume: 27, Issue:6

Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; HEK293 Cells; Humans; Leucine; Leucine-tRNA Ligase; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Signal Transduction; Structure-Activity Relationship

2019