leucine and fluorouracil

leucine has been researched along with fluorouracil in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	36 (75.00)	18.7374
1990's	1 (2.08)	18.2507
2000's	1 (2.08)	29.6817
2010's	7 (14.58)	24.3611
2020's	3 (6.25)	2.80

Authors

Authors	Studies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Come, SE; Eastman, RC; Gorden, P; Kahn, CR; Strewler, GJ	1
Endo, H; Kuwano, M; Tanaka, K	1
Sandborg, RR; Siegel, IA	1
Cherñavsky, A; Levin, E	1
Herberman, RB; Hiserodt, JC; Sarneva, M; Van den Brink, MR; Vujanovic, NL	1
Abe, F; Ashizawa, J; Horinishi, H; Ishizuka, M; Matsuda, A; Shibuya, K; Takahashi, K; Takeuchi, T; Umezawa, H	1
Granick, S; Kappas, A	1
Seeber, S; Warnecke, P; Weitzel, G	1
Kummer, D	1
Marzluf, GA	1
Korfsmeier, KH	1
Dickson, JA; Suzangar, M	1
Goswami, MN; Khouvine, Y; Sripati, CE	1
Leaver, CJ; Lovett, JS	1
Capizzi, RL; Nahas, A	1
Gagliardino, JJ; Mercer, RG; Rebolledo, OR	1
Gray, PN; Rachmeller, M	1
Sköld, O	1
Brozmanová, J; Sedliaková, M; Slezáriková, V; Stefunková, E	1
Mueller, M; Russo, V; Selzer, G; Stahl, FW; Yegian, CD	1
Pine, MJ	1
Applewhite, PB; Gardner, FT	1
Hand, RE; Tennant, RW	1
Bohunická, E; Krempaský, V; Kuzela, S; Ujházy, V	1
Key, JL; Leaver, CJ	1
Crudup, K; Sells, BH	1
Andrean, BA; De Kloet, SR; Hendricks, DV	1
Hignett, RC	1
Rowe, PB; Wyngaarden, JB	1
Stenram, U	1
Lee, KL; Miller, ON	1
Gallant, JA; Weisberg, RA	1
Ford, CH; Howell, A; Newman, CE; Wilson, AP	1
Carlsson, J; Malmqvist, M; Nederman, T	1
GALLANT, J; STAPLETON, R	1
ARONSON, AI; ROSASDELVALLE, M	1
SOFFER, RL	1
Cui, DX; Gao, ZQ; Guo, XX; Liu, SM; Ma, WQ; Wang, B; Wang, XJ; Zhang, XR; Zhao, TK	1
Hou, J; Huang, Y; Li, J; Wang, X; Xu, W; Zhang, Y	1
Dai, G; Duan, Y; Shi, LH; Sun, ZP; Wang, XJ; Xu, WF; Zhang, J; Zhang, XR	1
Asaoka, T; Doki, Y; Eguchi, H; Gotoh, K; Kawamoto, K; Mori, M; Noda, T; Ogawa, H; Umeshita, K; Wada, H; Yamada, D; Yamashita, M	1
Hou, J; Huang, Y; Jia, Y; Jiang, Y; Li, X; Wang, X; Xu, W; Zhang, J; Zhang, Y; Zou, M	1
Dou, C; Fang, C; Fu, X; Li, D; Liu, H; Liu, Z; Wang, H; Wang, X; Wu, H; Xu, W; Zhang, J; Zhang, Y; Zhao, Y; Zhu, D	1
Hou, J; Huang, Y; Jia, Y; Jiang, Y; Li, X; Wang, Q; Wang, X; Xu, W; Zhang, J; Zhang, Y	1
Ding, GG; Ling, XA; Wan, J; Wang, J; Wang, X	1
Hou, X; Jia, G; Jiang, Y; Li, P; Li, X; Tan, L; Wang, X; Xu, W; Yue, K; Zhang, J; Zhang, L; Zhang, Z	1
Dijk, FJ; Dorresteijn, B; Furber, MJW; Kranenburg, O; May, AM; Quirindongo, H; Raats, DAE; van Dijk, M; Wijler, LA	1

Other Studies

48 other study(ies) available for leucine and fluorouracil

Article	Year
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Adriamycin therapy for advanced insulinoma. The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1 Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diazoxide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Prednisone; Streptozocin; Tolbutamide	1977
Effect of cytochalasin-B on the transport of 5-fluorouracil in cultured mammalian cells. Gan, 1975, Volume: 66, Issue:3 Topics: Cell Membrane Permeability; Cells, Cultured; Cytochalasin B; Fluorouracil; Glucosamine; Leucine; Uridine	1975
Effects of 5-fluorouracil on protein synthesis and secretion of the rat parotid gland. Archives of oral biology, 1990, Volume: 35, Issue:12 Topics: Amylases; Animals; Cytoplasmic Granules; DNA; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Isoproterenol; Leucine; Male; Muramidase; Organ Size; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA; Saliva; Salivary Proteins and Peptides; Water	1990
Effect of antineoplastic drugs and estradiol on leucine uptake and proliferation of Ehrlich tumor cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1989, Volume: 43, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Doxorubicin; Estradiol; Fluorouracil; Leucine; Methotrexate; Mice; Mice, Inbred Strains; Tamoxifen	1989
Lymphokine-activated killer cells in rats: generation of natural killer cells and lymphokine-activated killer cells from bone marrow progenitor cells. Cellular immunology, 1989, Volume: 118, Issue:2 Topics: Animals; Antigens, Differentiation; Bone Marrow Cells; Cell Differentiation; Fluorouracil; G(M1) Ganglioside; Glycosphingolipids; Killer Cells, Natural; Leucine; Lymphocyte Activation; Lymphokines; Rats; Rats, Inbred F344	1989
Enhancement of antitumor effect of cytotoxic agents by bestatin. The Journal of antibiotics, 1985, Volume: 38, Issue:3 Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Drug Synergism; Female; Fluorouracil; Leucine; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Neoplasms, Experimental	1985
Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process. The Journal of biological chemistry, 1968, Jan-25, Volume: 243, Issue:2 Topics: Acetates; Amides; Animals; Azaserine; Azo Compounds; Chick Embryo; Culture Techniques; Cycloheximide; Dactinomycin; Floxuridine; Fluorine; Fluorouracil; Glucosamine; Glucose; Glucuronates; Hexosephosphates; Leucine; Liver; Mitomycins; Organometallic Compounds; Phenylalanine; Porphyrias; Porphyrins; Pregnanes; Puromycin; Uracil Nucleotides	1968
[Comparative in vitro studies with 5-fluorouracil and some of its derivatives]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1969, Volume: 350, Issue:6 Topics: Acyltransferases; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Depression, Chemical; DNA Nucleotidyltransferases; DNA, Neoplasm; Floxuridine; Fluorine; Fluorouracil; In Vitro Techniques; Leucine; Neoplasm Proteins; Nucleotides; RNA, Neoplasm; Thymidine; Uridine	1969
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro]. Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1 Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine	1970
Regeneration of invertase in Neurospora crassa. Journal of bacteriology, 1973, Volume: 115, Issue:1 Topics: Acetates; Acid Phosphatase; Biological Transport, Active; Carbon Isotopes; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Repression; Fluorouracil; Glucose; Hydrogen-Ion Concentration; Leucine; Mannose; Mycotoxins; Neurospora; Neurospora crassa; Rifamycins; Spores, Fungal; Sucrase; Uracil	1973
[Effect of 5-fluorouracil on protein metabolism of tumors and normal tissues in culture]. Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1 Topics: Adenocarcinoma; Animals; Autoradiography; Carcinoma, Basal Cell; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Depression, Chemical; Fluorouracil; Haplorhini; Humans; Kidney; Leucine; Neoplasm Proteins; Protein Biosynthesis; Simian virus 40; Skin; Tritium; Tyrosine	1970
In vitro-in vivo studies on the susceptibility of the solid Yoshida sarcoma to drugs and hyperthermia (42 degrees). Cancer research, 1974, Volume: 34, Issue:6 Topics: Animals; Antineoplastic Agents; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Cells, Cultured; Cyclophosphamide; Dactinomycin; Fluorouracil; Glycolysis; Hot Temperature; Leucine; Mesylates; Oxygen Consumption; Rats; Sarcoma, Yoshida; Thymidine; Time Factors; Uridine; Vinblastine	1974
[On the existance of adaptation inhibitors of hepatic tyrosine aminotransferase (Ec. 2.6.1.5) in adult rats]. Journal de physiologie, 1967, Volume: 59, Issue:1 Topics: Adrenalectomy; Age Factors; Animals; Azaguanine; Carbon Isotopes; Depression, Chemical; Fasting; Fluorouracil; Hydrocortisone; Leucine; Liver; Microsomes; Rats; Stimulation, Chemical; Stress, Physiological; Tyrosine; Tyrosine Transaminase	1967
An analysis of protein and RNA synthesis during encystment and outgrowth (germination) of Blastocladiella zoospores. Cell differentiation, 1974, Volume: 3, Issue:3 Topics: Buffers; Carbon Radioisotopes; Centrifugation, Density Gradient; Culture Media; Cycloheximide; Dactinomycin; Fluorouracil; Fungal Proteins; Fungi; Leucine; Methods; Microscopy, Electron; Polyribosomes; Ribosomes; RNA; RNA, Messenger; RNA, Ribosomal; Spores, Fungal; Tritium; Uridine	1974
Effect of in vivo treatment with L-asparaginase on the in vitro uptake and phosphorylation of some antileukemic agents. Cancer research, 1974, Volume: 34, Issue:10 Topics: Animals; Antimetabolites; Asparaginase; Biological Transport; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Leucine; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Oxidative Phosphorylation; Tetrahydrofolate Dehydrogenase; Time Factors	1974
Circadian variability in the effect of two inhibitors of protein synthesis. International journal of chronobiology, 1974, Volume: 2, Issue:2 Topics: Animals; Circadian Rhythm; Cycloheximide; Diaphragm; Female; Fluorouracil; Leucine; Mice; Proteins; Time Factors; Tritium	1974
The effect of 5-fluorouracil and 6-thioguanine incorporation on the amino acid acceptor activity of Escherichia coli tRNA. Biochimica et biophysica acta, 1967, Apr-18, Volume: 138, Issue:2 Topics: Alanine; Amino Acids; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Fluorouracil; Glutamates; Leucine; Lysine; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Thioguanine; Tyrosine; Valine	1967
Regulation of early RNA synthesis in bacteriophage T4-infected Escherichia coli cells. Journal of molecular biology, 1970, Nov-14, Volume: 53, Issue:3 Topics: Carbon Isotopes; Coliphages; Escherichia coli; Fluorouracil; Kinetics; Leucine; Mutation; RNA, Messenger; RNA, Viral; Temperature; Thymidine; Tritium; Uridine	1970
Effect of 5-fluorouracil posttreatment on sensitivity to ultraviolet radiation and course of messenger RNA synthesis in Escherichia coli cells. Folia microbiologica, 1971, Volume: 16, Issue:2 Topics: Agar; Amino Acids; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Colorimetry; Culture Media; DNA Replication; DNA, Bacterial; Escherichia coli; Fluorouracil; Glucose; Leucine; Nucleosides; Phenylalanine; Radiation Effects; RNA, Bacterial; RNA, Messenger; Time Factors; Ultraviolet Rays; Uracil	1971
Properties of the DNA-delay mutants of bacteriophage T4. Virology, 1971, Volume: 46, Issue:3 Topics: Aniline Compounds; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Coliphages; DNA Replication; DNA, Bacterial; DNA, Viral; Escherichia coli; Fluorouracil; Genes, Recessive; Genetic Complementation Test; Genetics, Microbial; Leucine; Muramidase; Mutation; Nitrogen Isotopes; RNA, Messenger; Thymidine; Time Factors; Tritium; Uracil; Viral Proteins; Virus Replication	1971
Response of intracellular proteolysis to alteration of bacterial protein and the implications in metabolic regulation. Journal of bacteriology, 1967, Volume: 93, Issue:5 Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Canavanine; Carbon Isotopes; Chloramphenicol; Dactinomycin; Escherichia coli; Fluorouracil; Leucine; Phenylalanine; Puromycin; Temperature; Ultraviolet Rays	1967
Protein and RNA inhibitors and protozoan habituation. Psychopharmacologia, 1970, Volume: 16, Issue:5 Topics: Acridines; Benzimidazoles; Chloramphenicol; Ciliophora; Dactinomycin; Depression, Chemical; Fluorouracil; Habituation, Psychophysiologic; Learning; Leucine; Memory; Protein Biosynthesis; Puromycin; RNA; Uridine	1970
Requirement of cellular synthesis for Kilham rat virus replication. Virology, 1970, Volume: 42, Issue:4 Topics: Animals; Autoradiography; Culture Techniques; DNA; Fluorescent Antibody Technique; Fluorouracil; Herpesviridae; Leucine; Radiation Effects; Rats; Species Specificity; Thymidine; Tritium; Ultraviolet Rays; Uridine; Virus Cultivation; Virus Replication; Viruses, Unclassified	1970
Resistance of amino acid incorporation by mitochondria isolated from Ehrlich ascites tumour cells to the in vivo treatment with 5-fluorouracil. Neoplasma, 1972, Volume: 19, Issue:1 Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Fluorouracil; In Vitro Techniques; Leucine; Mice; Mitochondria; Organelle Biogenesis	1972
Polyribosome formation and RNA synthesis during aging of carrot-root tissue. Proceedings of the National Academy of Sciences of the United States of America, 1967, Volume: 57, Issue:5 Topics: Carbon Isotopes; Dactinomycin; Fluorouracil; In Vitro Techniques; Leucine; Nucleosides; Phosphorus Isotopes; Plants, Edible; Preservation, Biological; Ribosomes; RNA; Tritium; Vegetables	1967
Ribosome production during recovery from puromycin treatment: influence of 5-fluorouracil. Biochimica et biophysica acta, 1966, Aug-17, Volume: 123, Issue:2 Topics: Bacterial Proteins; Centrifugation, Density Gradient; Escherichia coli; Fluorouracil; Leucine; Puromycin; Ribosomes; RNA, Bacterial	1966
Effects of cycloheximide and 5-fluorouracil on formation of low-molecular-weight ribonucleic acid in yeast. Journal of bacteriology, 1969, Volume: 97, Issue:2 Topics: Adenine; Carbon Isotopes; Chromatography; Chromatography, Gel; Cycloheximide; Fluorouracil; Leucine; Methionine; Nucleic Acid Denaturation; Nucleotides; Phosphates; Phosphorus Isotopes; Ribosomes; RNA; RNA, Transfer; Saccharomyces; Urea	1969
Interference of 5-fluorouracil in the biosynthesis of ribosomes in Staphylococcus aureus (strain Duncan). Biochimica et biophysica acta, 1966, Mar-21, Volume: 114, Issue:3 Topics: Fluorouracil; In Vitro Techniques; Leucine; Ribosomes; Staphylococcus; Ultracentrifugation	1966
The mechanism of dietary alterations in rat hepatic xanthine oxidase levels. The Journal of biological chemistry, 1966, Dec-10, Volume: 241, Issue:23 Topics: Animals; Dactinomycin; Dietary Proteins; Fluorouracil; In Vitro Techniques; Leucine; Liver; Orotic Acid; Puromycin; Rats; RNA; Xanthine Oxidase	1966
Cytological, radioautographic and ultrastructural studies on the effect of 5-fluorouracil on rat liver. Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1966, Volume: 71, Issue:2 Topics: Animals; Autoradiography; Cell Nucleus; Fluorouracil; Leucine; Liver; Male; Microscopy, Electron; Nucleosides; Protein Biosynthesis; Rats; RNA; Tritium	1966
Studies on triiodothyronine-induced synthesis of liver mitochondrial alpha-glycerophosphate dehydrogenase in the thyroidectomized rat. Molecular pharmacology, 1967, Volume: 3, Issue:1 Topics: Animals; Carbon Isotopes; Dactinomycin; Enzyme Induction; Ethionine; Fluorouracil; Glycerolphosphate Dehydrogenase; Leucine; Liver; Mitochondria; Puromycin; Rats; Thyroidectomy; Triiodothyronine	1967
Dual function of the lambda prophage repressor. Journal of molecular biology, 1967, May-14, Volume: 25, Issue:3 Topics: Adenine; Coliphages; DNA, Viral; Fluorouracil; Hot Temperature; Leucine; Molecular Biology; Mutation; Thymidine; Viral Proteins	1967
A comparison of three assays used for the in vitro chemosensitivity testing of human tumours. British journal of cancer, 1984, Volume: 49, Issue:1 Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cell Survival; Cisplatin; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Leucine; Neoplasms, Experimental; Nucleotides; Rats	1984
Penetration of substances into tumor tissue--a methodological study on cellular spheroids. In vitro, 1981, Volume: 17, Issue:4 Topics: Albumins; Biological Transport; Cell Line; Clone Cells; Fluorouracil; Glioma; Humans; Leucine; Models, Biological; Neoplasms; Thymidine; Vinblastine	1981
PHYSIOLOGICAL EVIDENCE ON THE NATURE OF THE REPRESSOR OF ALKALINE PHOSPHATASE SYNTHESIS IN ESCHERICHIA COLI. Journal of molecular biology, 1964, Volume: 8 Topics: Alkaline Phosphatase; Bacterial Proteins; Chloramphenicol; Culture Media; Enzyme Inhibitors; Escherichia coli; Fluorouracil; Leucine; Metabolism; Mutation; Pharmacology; Phosphates; Proteins; Research; Temperature; Thymine	1964
RNA AND PROTEIN SYNTHESIS REQUIRED FOR BACTERIAL SPORE FORMATION. Biochimica et biophysica acta, 1964, Jun-22, Volume: 87 Topics: Azaguanine; Bacillus cereus; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Dactinomycin; Drug Resistance; Drug Resistance, Microbial; Fluorouracil; Leucine; Pharmacology; Protein Biosynthesis; Proteins; Research; RNA; RNA, Bacterial; RNA, Messenger; Spores; Spores, Bacterial; Tritium	1964
STUDIES ON THE BIOLOGICAL ACTIVITY OF RIBONUCLEIC ACID ISOLATED FROM ESCHERICHIA COLI AFTER EXPOSURE TO 5-FLUOROURACIL. Biochimica et biophysica acta, 1964, Jul-22, Volume: 87 Topics: Arginine; Escherichia coli; Fluorouracil; Leucine; Metabolism; Pharmacology; Proline; Proteins; Research; RNA; RNA, Bacterial; Serine; Spectrophotometry	1964
Preliminary detection of the anti‑tumour activity of indoline‑2,3‑dione derivative DH‑12a targeting aminopeptidase N. Molecular medicine reports, 2014, Volume: 10, Issue:5 Topics: Animals; Antineoplastic Agents; CD13 Antigens; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Hydroxamic Acids; Indoles; Inhibitory Concentration 50; Leucine; Lung Neoplasms; Mice; Tumor Burden; Xenograft Model Antitumor Assays	2014
Enhanced anticancer activity of 5-FU in combination with Bestatin: Evidence in human tumor-derived cell lines and an H22 tumor-bearing mouse. Drug discoveries & therapeutics, 2015, Volume: 9, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Synergism; Fluorouracil; Humans; Leucine; Mice; Neoplasms, Experimental	2015
Aminopeptidase N inhibitor 4cc synergizes antitumor effects of 5-fluorouracil on human liver cancer cells through ROS-dependent CD13 inhibition. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 76 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Line, Tumor; Drug Synergism; Female; Fluorouracil; Humans; Hydroxamic Acids; Leucine; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Urea; Xenograft Model Antitumor Assays	2015
A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. International journal of oncology, 2016, Volume: 49, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Cycle; Cell Line, Tumor; Cisplatin; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Leucine; Liver Neoplasms; Neoplastic Stem Cells; Niacinamide; Phenylurea Compounds; Reactive Oxygen Species; Sorafenib	2016
Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Fluorouracil; Leucine; Mice; Neoplasm Metastasis; Prodrugs; Xenograft Model Antitumor Assays	2016
BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage. International journal of oncology, 2017, Volume: 51, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA Damage; Female; Fluorouracil; Humans; Leucine; Liver Neoplasms; Mice; Mice, Nude; Neoplastic Stem Cells; Reactive Oxygen Species; Up-Regulation; Xenograft Model Antitumor Assays	2017
Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Leucine; Mice; Mice, Inbred Strains; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship	2018
Inhibitory effect of Ubenimex combined with fluorouracil on multiple drug resistance and P-glycoprotein expression level in non-small lung cancer. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:21 Topics: A549 Cells; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Leucine; Lung Neoplasms; Mice, Inbred C57BL; Mice, Nude; RNA, Messenger	2020
Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy. Bioorganic chemistry, 2021, Volume: 116 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Leucine; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship	2021
Oncotarget, 2022, 10-08, Volume: 13 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Caspase 3; Cholecalciferol; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Leucine; Mice; Muscle, Skeletal; Nutritional Support; Oxaliplatin; Treatment Outcome	2022