leucascandrolide-a has been researched along with indole* in 1 studies
1 other study(ies) available for leucascandrolide-a and indole
Article | Year |
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Iodocyclization and Prins-type macrocyclization: an efficient formal synthesis of leucascandrolide A.
The formal total synthesis of leucascandrolide A has been achieved in 20 steps from a known epoxide with an overall yield of 11.5% following a recently developed strategy for the construction of trans-2,6-disubstituted-3,4-dihydropyrans and a Lewis acid catalyzed intramolecular Prins-cyclization of an aldehydic homoallylic alcohol to generate the tetrahydropyran ring with three stereogenic centers and macrocycle concomitantly. Topics: Catalysis; Cyclization; Indoles; Lewis Acids; Macrocyclic Compounds; Molecular Structure; Sesquiterpenes | 2011 |