letrozole and vorozole

letrozole has been researched along with vorozole in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (33.33)18.2507
2000's11 (40.74)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belluti, F; Bertucci, C; Bisi, A; Cavalli, A; Giorgio, E; Gobbi, S; Hartmann, RW; Paluszcak, A; Piazzi, L; Rampa, A; Recanatini, M; Rosini, C; Valenti, P1
Abbate, S; Castiglioni, E; Labrosse, JR; Lebon, F; Longhi, G; Potter, BV; Purohit, A; Reed, MJ; Trusselle, MN; Woo, LW; Wood, PM1
Muftuoglu, Y; Mustata, G1
Potter, BV; Thomas, MP1
Dowsett, M2
Spencer, CM; Wiseman, LR1
Buzdar, AU; Roseman, BJ; Singletary, SE1
Harvey, HA1
Hamilton, A; Piccart, M1
Blijham, GH; de Jong, PC1
Bonneterre, J; Feutrie, ML1
Harvey, HA; Santen, RJ1
Bajetta, E; Bichisao, E; Pozzi, P; Toffolatti, L; Zilembo, N1
Auvray, P; Bichat, F; Genne, P1
de Crémoux, P1
Kerbrat, P; Lefeuvre, C1
Buzdar, A; Howell, A1
Mokbel, K1
Clemons, MJ; Freedman, OC; Verma, S1
Bria, E; Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Felici, A; Ferretti, G; Giannarelli, D; Milella, M; Mottolese, M; Nisticò, C; Papaldo, P; Ruggeri, EM; Terzoli, E1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP1
Jiao, J; Liao, Q; Xiang, H1
Mahon, MF; Potter, BV; Purohit, A; Thomas, MP; Woo, LW; Wood, PM1
Hosoya, T; Kusuhara, H; Miyajima, M; Sugiyama, Y; Takahashi, K; Takashima, T; Watanabe, Y1
Biegon, A; Fowler, JS; Kim, SW; Logan, J; Pareto, D; Telang, F; Wang, GJ1
Alexoff, DL; Biegon, A; Fowler, JS; Kim, SW; Logan, J; Pareto, D; Schlyer, D; Wang, GJ1

Reviews

18 review(s) available for letrozole and vorozole

ArticleYear
Vorozole.
    Drugs & aging, 1997, Volume: 11, Issue:3

    Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

1997
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer.
    Journal of surgical oncology, 1997, Volume: 66, Issue:3

    Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles

1997
Emerging role of aromatase inhibitors in the treatment of breast cancer.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:3 Suppl 5

    Topics: Aged; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Triazoles

1998
Theoretical considerations for the ideal aromatase inhibitor.
    Breast cancer research and treatment, 1998, Volume: 49 Suppl 1

    Topics: Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles

1998
The third-generation non-steroidal aromatase inhibitors: a review of their clinical benefits in the second-line hormonal treatment of advanced breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:4

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Belgium; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Severity of Illness Index; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles

1999
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women.
    The Netherlands journal of medicine, 1999, Volume: 55, Issue:2

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles

1999
[Aromatase inhibitors].
    Bulletin du cancer, 1999, Volume: 86, Issue:10

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles

1999
Use of aromatase inhibitors in breast carcinoma.
    Endocrine-related cancer, 1999, Volume: 6, Issue:1

    Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles

1999
Steroidal aromatase inhibitors in elderly patients.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2000
[Preclinical evaluation of aromatase inhibitors antitumor activity].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles

2000
[Aromatase inhibitors: pharmacological aspects].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles

2000
[Aromatase inhibitors: a review of clinical trials].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles

2000
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9

    Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting

2001
The evolving role of aromatase inhibitors in breast cancer.
    International journal of clinical oncology, 2002, Volume: 7, Issue:5

    Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Humans; Letrozole; Nitriles; Triazoles

2002
Using aromatase inhibitors in the neoadjuvant setting: evolution or revolution?
    Cancer treatment reviews, 2005, Volume: 31, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Evidence-Based Medicine; Female; Humans; Letrozole; Mastectomy, Segmental; Neoadjuvant Therapy; Nitriles; Randomized Controlled Trials as Topic; Receptors, Estrogen; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles

2005
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles

2005
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
    Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18

    Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles

2006
Recent advancement in nonsteroidal aromatase inhibitors for treatment of estrogen-dependent breast cancer.
    Current medicinal chemistry, 2010, Volume: 17, Issue:30

    Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Chromones; Coumarins; Female; Flavonoids; Humans; Letrozole; Nitriles; Receptors, Estrogen; Sulfonamides; Triazoles

2010

Other Studies

9 other study(ies) available for letrozole and vorozole

ArticleYear
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach.
    Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23

    Topics: Aromatase; Aromatase Inhibitors; Benzopyrans; Circular Dichroism; Drug Design; Humans; Ligands; Microsomes; Models, Molecular; Molecular Conformation; Placenta; Quantitative Structure-Activity Relationship; Spectrophotometry, Ultraviolet; Stereoisomerism; Steroid 17-alpha-Hydroxylase

2005
Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Aromatase; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Humans; Letrozole; Molecular Structure; Nitriles; Stereoisomerism; Steryl-Sulfatase; Structure-Activity Relationship; Triazoles

2008
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship

2010
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators

2015
Aromatase inhibitors come of age.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7

    Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles

1997
Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates.
    ChemMedChem, 2011, Aug-01, Volume: 6, Issue:8

    Topics: Aromatase; Aromatase Inhibitors; Binding Sites; Catalytic Domain; Cell Line, Tumor; Computer Simulation; Crystallography, X-Ray; Enzyme Activation; Humans; Letrozole; Nitriles; Stereoisomerism; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Triazoles

2011
Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:9

    Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Brain; Cell Line; Humans; Letrozole; Male; Mice; Nitriles; Triazoles

2013
Kinetic analysis of [11C]vorozole binding in the human brain with positron emission tomography.
    Molecular imaging, 2014, Volume: 13

    Topics: Adult; Aged; Aromatase Inhibitors; Carbon Radioisotopes; Cerebellum; Female; Humans; Letrozole; Male; Middle Aged; Nitriles; Positron-Emission Tomography; Thalamus; Tissue Distribution; Triazoles; Young Adult

2014
Aromatase imaging with [N-methyl-11C]vorozole PET in healthy men and women.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:4

    Topics: Adult; Age Factors; Aged; Aromatase; Aromatase Inhibitors; Diagnostic Imaging; Female; Healthy Volunteers; Humans; Letrozole; Liver; Male; Middle Aged; Nitriles; Positron-Emission Tomography; Radiometry; Radiopharmaceuticals; Reproducibility of Results; Sex Factors; Software; Triazoles; Whole-Body Irradiation; Young Adult

2015