Compounds > letrozole

letrozole and methotrexate

letrozole has been researched along with methotrexate in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (23.08)	29.6817
2010's	8 (61.54)	24.3611
2020's	2 (15.38)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bouboukas, G; Kalofonos, H; Koutras, A; Makatsoris, T; Onyenadum, A; Peroukides, S; Starakis, I	1
Barba, M; Del Medico, P; Di Lauro, L; Giannarelli, D; Laudadio, L; Maugeri-Saccà, M; Pizzuti, L; Sergi, D; Tomao, S; Vici, P	1
Almajed, MM; Esfahani, K; Panasci, L; Pelmus, M	1
Abdo, M; Fekry, E; Makary, S	1
Abdalla, KA; Abdalla, NK; Hassanin, KMA; Hozayen, WG; Mitwally, MF	1
Auger, N; Ayoub, A; Wei, SQ	1

Reviews

1 review(s) available for letrozole and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

12 other study(ies) available for letrozole and methotrexate

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Prolonged survival of neoplastic meningitis from breast cancer with letrozole and intrathecal methotrexate: a case report. Journal of neuro-oncology, 2011, Volume: 101, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Injections, Spinal; Letrozole; Meningitis; Methotrexate; Middle Aged; Nitriles; Prognosis; Survival Rate; Triazoles	2011
Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer. Breast cancer research and treatment, 2013, Volume: 141, Issue:1 Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Epirubicin; Estrogen Receptor Modulators; Estrogens; Fluorouracil; Gonadotropin-Releasing Hormone; Goserelin; Humans; Kaplan-Meier Estimate; Letrozole; Male; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Progesterone; Radiotherapy, Adjuvant; Tamoxifen; Taxoids; Triazoles	2013
Complete response and long-term survival of leptomeningeal carcinomatosis from breast cancer with maintenance endocrine therapy. BMJ case reports, 2016, Jun-02, Volume: 2016 Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Letrozole; Meningeal Carcinomatosis; Methotrexate; Nitriles; Spinal Neoplasms; Triazoles	2016
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect. Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:4 Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract; Inflammation; Letrozole; Male; Methotrexate; Nitriles; Organ Size; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Testosterone; Triazoles	2018
Aromatase inhibitor letrozole: a novel treatment for ectopic pregnancy. Fertility and sterility, 2020, Volume: 114, Issue:2 Topics: Abortifacient Agents, Nonsteroidal; Adolescent; Adult; Anti-Mullerian Hormone; Aromatase Inhibitors; Biomarkers; Chorionic Gonadotropin, beta Subunit, Human; Female; Humans; Letrozole; Methotrexate; Pregnancy; Pregnancy, Ectopic; Time Factors; Treatment Outcome; Young Adult	2020
Letrozole: future alternative to methotrexate for treatment of ectopic pregnancy? Fertility and sterility, 2020, Volume: 114, Issue:2 Topics: Abortifacient Agents, Nonsteroidal; Aromatase Inhibitors; Female; Humans; Letrozole; Methotrexate; Pregnancy; Pregnancy, Ectopic	2020