letrozole has been researched along with megestrol acetate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 7 (30.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellmunt, J; Bezwoda, W; Chaudri, HA; Dombernowsky, P; Falkson, G; Fornasiero, A; Gardin, G; Gudgeon, A; Hatschek, T; Hoffmann, W; Hornberger, U; Leonard, R; Michel, J; Morgan, M; Panasci, L; Smith, I; Tjabbes, T; Trunet, PF | 1 |
| Harvey, HA | 1 |
| Smith, IE | 1 |
| Blijham, GH; de Jong, PC | 1 |
| Chaudri, HA; Trunet, PF | 1 |
| Dranitsaris, G; Leung, P; Mather, J; Oza, A | 1 |
| Brady, C; Buzdar, A; Davidson, N; Douma, J; Elledge, R; Morgan, M; Nabholtz, J; Porter, L; Smith, R; Xiang, X | 1 |
| Joy, AA; Mackey, JR | 1 |
| Buzdar, AU | 1 |
| Ingle, JN | 1 |
| Burton, G; Kleeberg, U; Mauriac, L; Osborne, CK; Robertson, JF; Vergote, I | 1 |
| Rose, C | 1 |
| Campos, SM | 1 |
| Ingle, JN; Suman, VJ | 1 |
| DiLeonardo, M; Gibbons, G; Resnik, KS | 1 |
| Buist, MR; Dahhan, T; Fons, G; Ten Kate, FJ; van der Velden, J | 1 |
| Buist, MR; Kenter, GG; van der Velden, J; van Driel, WJ; van Lonkhuijzen, LR; van Meurs, HS | 1 |
| Batson, S; Jones, N; Livings, C; Telford, C | 1 |
| Mirmohammadkhanai, M; Moradan, S; Nikkhah, N | 1 |
| Choi, YM; Kim, H; Kim, SH; Kim, SW; Ku, SY; Suh, CS | 1 |
| Churchman, M; Dawson, C; Gourley, C; Herrington, CS; Hollis, RL; Mackean, MJ; Nunes, H; Nussey, F; Rye, T; Stanley, B; Towler, JD; Yan, X | 1 |
8 review(s) available for letrozole and megestrol acetate
| Article | Year |
|---|---|
Emerging role of aromatase inhibitors in the treatment of breast cancer.
Topics: Aged; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 1998 |
Pivotal trials of letrozole: a new aromatase inhibitor.
Topics: Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Treatment Outcome; Triazoles | 1998 |
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles | 1999 |
A summary of second-line randomized studies of aromatase inhibitors.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Enzyme Inhibitors; Estrogen Receptor Modulators; Fadrozole; Female; Humans; Letrozole; Megestrol Acetate; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2001 |
A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Aromatase inhibitors for breast cancer in postmenopausal women.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2004 |
Aromatase inhibitors for therapy of advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Evaluation; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Network Meta-Analysis Comparing Overall Survival for Fulvestrant 500 mg Versus Alternative Therapies for Treatment of Postmenopausal, Estrogen Receptor-Positive Advanced Breast Cancer Following Failure on Prior Endocrine Therapy.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Network Meta-Analysis; Nitriles; Postmenopause; Receptors, Estrogen; Treatment Outcome; Triazoles | 2016 |
4 trial(s) available for letrozole and megestrol acetate
| Article | Year |
|---|---|
Letrozole, a new oral aromatase inhibitor for advanced breast cancer: double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Survival Rate; Triazoles | 1998 |
Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate.
Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Proportional Hazards Models; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2001 |
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles | 2003 |
Comparing the Administration of Letrozole and Megestrol Acetate in the Treatment of Women with Simple Endometrial Hyperplasia without Atypia: A Randomized Clinical Trial.
Topics: Administration, Oral; Adult; Endometrial Hyperplasia; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Pilot Projects; Triazoles | 2017 |
11 other study(ies) available for letrozole and megestrol acetate
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Letrozole: updated duration of response.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Survival Analysis; Triazoles | 1999 |
Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Costs and Cost Analysis; Decision Support Techniques; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Triazoles | 2000 |
Letrozole in second-line therapy of advanced breast cancer: more questions than answers.
Topics: Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Europe; Female; Humans; Letrozole; Megestrol Acetate; Neoplasm Metastasis; Nitriles; Palliative Care; Postmenopause; Treatment Outcome; Triazoles | 2001 |
Estrogen as therapy for breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase II as Topic; Diethylstilbestrol; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Salvage Therapy; Tamoxifen; Treatment Outcome; Triazoles | 2002 |
Clinically occult cutaneous metastases.
Topics: Aged; Aged, 80 and over; Anastrozole; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Capecitabine; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Lobular; Carcinoma, Signet Ring Cell; Deoxycytidine; Estradiol; Facial Neoplasms; Female; Fluorouracil; Fulvestrant; Humans; Incidental Findings; Letrozole; Mastectomy, Radical; Megestrol Acetate; Melanoma; Neoplasms, Second Primary; Neoplastic Cells, Circulating; Nitriles; Selective Estrogen Receptor Modulators; Skin Neoplasms; Tamoxifen; Triazoles; Wound Healing | 2006 |
The efficacy of hormonal treatment for residual or recurrent low-grade endometrial stromal sarcoma. A retrospective study.
Topics: Adult; Aged, 80 and over; Aromatase Inhibitors; Combined Modality Therapy; Dose-Response Relationship, Drug; Endometrial Neoplasms; Female; Humans; Hysterectomy; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Progestins; Retrospective Studies; Sarcoma, Endometrial Stromal; Secondary Prevention; Treatment Outcome; Triazoles | 2009 |
Evaluation of response to hormone therapy in patients with measurable adult granulosa cell tumors of the ovary.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chemotherapy, Adjuvant; Disease Progression; Disease-Free Survival; Female; Goserelin; Granulosa Cell Tumor; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Ovarian Neoplasms; Ovariectomy; Radiotherapy, Adjuvant; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Salpingectomy; Tamoxifen; Triazoles | 2015 |
A successful live birth with in vitro fertilization and thawed embryo transfer after conservative treatment of recurrent endometrial cancer.
Topics: Adult; Antineoplastic Agents, Hormonal; Conservative Treatment; Cryopreservation; Embryo Transfer; Endometrial Neoplasms; Female; Fertility Preservation; Fertilization in Vitro; Humans; Letrozole; Levonorgestrel; Live Birth; Megestrol Acetate; Neoplasm Recurrence, Local; Nitriles; Pregnancy; Pregnancy Outcome; Triazoles | 2018 |
Endocrine treatment of high grade serous ovarian carcinoma; quantification of efficacy and identification of response predictors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; CA-125 Antigen; Cystadenocarcinoma, Serous; Female; Humans; Letrozole; Megestrol Acetate; Membrane Proteins; Middle Aged; Neoplasm Grading; Ovarian Neoplasms; Predictive Value of Tests; Receptors, Estrogen; Retrospective Studies; Tamoxifen | 2019 |