letrozole and cyclin d1

letrozole has been researched along with cyclin d1 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Baselga, J; Bellet, M; Bianchi, G; Campone, M; Dixon, JM; Gardner, H; Greil, R; Jonat, W; Kubista, E; Lane, HA; Manikhas, A; Mayordomo, J; Molloy, B; Phillips, P; Rugo, HS; Semiglazov, V; Steinseifer, J; Stumm, M; Tokaji, E; van Dam, P1
Alfieri, RR; Belletti, S; Bonelli, MA; Bottini, A; Cavazzoni, A; Dowsett, M; Evans, DB; Fox, SB; Fumarola, C; Galetti, M; Gatti, R; Generali, D; Harris, AL; La Monica, S; Martin, LA; Petronini, PG1
Albrecht, JH; Anttila, C; Blomquist, CH; Delvoux, B; Hanse, EA; Mason, JI; Mullany, LK; Romano, A1
Bane, F; Byrne, C; Conroy, RM; Gaora, PÓ; Hao, Y; Hill, AD; McBryan, J; McIlroy, M; O'Hara, J; Tibbitts, P; Vareslija, D; Young, LS1
Aberdeen, GW; Albrecht, ED; Dumitrescu, A; Pepe, GJ1
Boer, K; Bondarenko, IM; Crown, JP; Ettl, J; Finn, RS; Fowst, C; Huang, X; Kim, ST; Kulyk, SO; Lang, I; Patel, R; Pinter, T; Randolph, S; Schmidt, M; Shparyk, Y; Slamon, DJ; Thummala, AR; Voytko, NL1
Yardley, DA1
Babu, VS; Jayakumaran Nair, A; Radhamany, PM; Surumi, B1

Trials

3 trial(s) available for letrozole and cyclin d1

ArticleYear
Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-01, Volume: 27, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers, Tumor; Biopsy; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Class I Phosphatidylinositol 3-Kinases; Cyclin D1; Double-Blind Method; Europe; Everolimus; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Mutation; Neoadjuvant Therapy; Nitriles; Palpation; Phosphatidylinositol 3-Kinases; Phosphorylation; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Ribosomal Protein S6 Kinases; Sirolimus; Time Factors; Treatment Outcome; Triazoles; United States

2009
The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study.
    The Lancet. Oncology, 2015, Volume: 16, Issue:1

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p16; Disease-Free Survival; Drug Administration Schedule; Europe; Female; Humans; Intention to Treat Analysis; Letrozole; Middle Aged; Molecular Targeted Therapy; Nitriles; North America; Piperazines; Postmenopause; Proportional Hazards Models; Protein Kinase Inhibitors; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Republic of Korea; South Africa; Time Factors; Treatment Outcome; Triazoles

2015
MONALEESA clinical program: a review of ribociclib use in different clinical settings.
    Future oncology (London, England), 2019, Volume: 15, Issue:23

    Topics: Adolescent; Adult; Aminopyridines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Estrogens; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Postmenopause; Progression-Free Survival; Purines; Receptor, ErbB-2; Tamoxifen; Young Adult

2019

Other Studies

5 other study(ies) available for letrozole and cyclin d1

ArticleYear
Synergistic activity of letrozole and sorafenib on breast cancer cells.
    Breast cancer research and treatment, 2010, Volume: 124, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; Aromatase; Aromatase Inhibitors; Benzenesulfonates; Breast Neoplasms; Caspase 7; Caspase 9; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cytochromes c; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Estradiol; Female; Humans; Letrozole; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Niacinamide; Nitriles; Phenylurea Compounds; Phosphoproteins; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins c-myc; Pyridines; Retinoblastoma Protein; Ribosomal Protein S6 Kinases, 70-kDa; Sorafenib; Testosterone; Time Factors; TOR Serine-Threonine Kinases; Transfection; Triazoles

2010
Cyclin D1 regulates hepatic estrogen and androgen metabolism.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:6

    Topics: Androgens; Animals; Aromatase Inhibitors; Cell Line, Tumor; Cyclin D1; Estrogens; Gene Expression Profiling; Gene Expression Regulation; Humans; Letrozole; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Nitriles; Triazoles

2010
AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-15, Volume: 18, Issue:12

    Topics: Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Letrozole; MAP Kinase Signaling System; Neoplasm Recurrence, Local; Nitriles; Nuclear Receptor Coactivator 3; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Transcription, Genetic; Trefoil Factor-1; Triazoles; Tumor Suppressor Proteins; Up-Regulation

2012
Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex.
    Endocrinology, 2014, Volume: 155, Issue:12

    Topics: Adrenal Cortex; Animals; Aromatase Inhibitors; Carrier Proteins; Cyclin D1; Cyclin-Dependent Kinases; Dehydroepiandrosterone Sulfate; Estradiol; Estrogens; Female; Fetal Development; Fetal Weight; Hydrocortisone; Ki-67 Antigen; Letrozole; Male; Nitriles; Papio anubis; Placenta; Pregnancy; Triazoles

2014
Novel studies on Isolation, purification and characterization of dibenzonitro compound from Glycosmis pentaphylla (Retz.) DC. and effect in downregulating neuronal cancers.
    Steroids, 2023, Volume: 198

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Letrozole; Neuroblastoma; Proliferating Cell Nuclear Antigen; RNA, Messenger; Rutaceae

2023