letrozole and androstenedione

letrozole has been researched along with androstenedione in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (35.29)	18.2507
2000's	24 (47.06)	29.6817
2010's	7 (13.73)	24.3611
2020's	2 (3.92)	2.80

Authors

Authors	Studies
Borja, J; Pérez, N	1
Brodie, A; Savinov, A; Wang, J; Yue, W	1
Junker Walker, U; Nogués, V	1
Ahern, J; Dowsett, M; Iveson, TJ; Smith, IE; Smithers, DA; Trunet, PF	1
Detre, S; Dowsett, M; Grimshaw, R; Lee, K; Macaulay, VM; Rowlands, M	1
Choate, JV; Resko, JA	1
Detre, S; Dowsett, M; Grimshaw, R; Rowlands, M	1
Dowsett, M	2
Buzdar, AU; Roseman, BJ; Singletary, SE	1
Dickson, RB; El-Ashry, D; Hannum, RS; Kern, FG; Kharbanda, S; Lopez, CA; Lorant, LA; McLeskey, SW; Tobias, CA; Trock, BJ; Zhang, L	1
Dowsett, M; Jacobs, S; Johnston, SR; Jones, A; Smith, IE; Trunet, P	1
Brodie, AM; Grigoryev, DN; Long, BJ; Thiantanawat, A; Tilghman, SL; Yue, W	1
Bershteĭn, LM; Larionov, AA; Poroshina, TE; Zimarina, TS	1
Blijham, GH; de Jong, PC	1
Bonneterre, J; Feutrie, ML	1
Brodie, AM; Njar, VC	1
Coombes, RC; Dowsett, M; Harper-Wynne, C	1
Harvey, HA; Santen, RJ	1
Bajetta, E; Bichisao, E; Pozzi, P; Toffolatti, L; Zilembo, N	1
Auvray, P; Bichat, F; Genne, P	1
de Crémoux, P	1
Kerbrat, P; Lefeuvre, C	1
Albrecht, ED; Babischkin, JS; Burleigh, DW; Mayhew, TM; Pepe, GJ	1
Buzdar, A; Howell, A	1
Carlini, P; Casali, A; Cognetti, F; De Marco, S; Fabi, A; Frassoldati, A; Nardi, M; Paoloni, F; Papaldo, P; Ruggeri, EM	1
Albrecht, ED; Billiar, RB; Pepe, GJ; Zachos, NC	1
Burton, G; Kleeberg, U; Mauriac, L; Osborne, CK; Robertson, JF; Vergote, I	1
Hori, H; Kagawa, N; Waterman, MR; Yoshioka, S	1
Lykkesfeldt, AE; Sonne-Hansen, K	1
Delozier, T; Khayat, D; Spano, JP	1
Bria, E; Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Felici, A; Ferretti, G; Giannarelli, D; Milella, M; Mottolese, M; Nisticò, C; Papaldo, P; Ruggeri, EM; Terzoli, E	1
Cernich, J; Jacobson, JD; Moore, WV; Popovic, J	1
Arteaga, CL; Miller, T; Shin, I	1
Brodie, A; Guo, Z; Macedo, LF; Qiu, Y; Sabnis, GJ; Tilghman, SL	1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP	1
Cheung, AM; Goss, PE; Hu, H; Qi, S	1
Andò, S; Barone, I; Casaburi, I; Catalano, S; Giordano, C; Gu, G; Lanzino, M; Marsico, S; Middea, E; Pellegrino, M; Rizza, P	1
Brodie, A; Goloubeva, O; Jelovac, D; Sabnis, G; Schayowitz, A	1
Blanchett, D; Demers, L; Goss, PE; Langecker, P; Ohorodnik, S; Santen, RJ; Settlage, J; Wang, S	1
Blanchett, D; Bondarenko, IN; Goss, P; Langecker, P; Manikhas, GN; Miller, WH; Pendergrass, KB	1
Dutta, U; Pant, K	1
Chen, S; Hong, Y; Rashid, R	1
Gallicchio, L; Helzlsouer, KJ; Macdonald, R; Rushovich, E; Wood, B	1
Chan, CC; Ho, PC; Lee, VC; Ng, EH; Yeung, WS	1
Gasco, M; Gonzales, GF; Gonzales-Castañeda, C; Tapia, V	1
Cheng, FX; Fu, J; Li, WH; Liu, GX; Shen, ZH; Tang, Y	1
Bane, F; Byrne, C; Conroy, RM; Gaora, PÓ; Hao, Y; Hill, AD; McBryan, J; McIlroy, M; O'Hara, J; Tibbitts, P; Vareslija, D; Young, LS	1
Gildea, JJ; Wang, J; Yue, W	1
Ball, BA; Daels, P; Dini, P; Esteller-Vico, A; Haneda, S; Nambo, Y; Scoggin, KE; Squires, EL; Troedsson, MH	1
Bülow, NS; Bungum, L; Macklon, NS; Poulsen, LC; Skouby, SO; Warzecha, AK; Yding Andersen, C	1

Reviews

20 review(s) available for letrozole and androstenedione

Article	Year
Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer. The Journal of international medical research, 1992, Volume: 20, Issue:4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Letrozole; Nitriles; Triazoles	1992
The control and biological importance of intratumoural aromatase in breast cancer. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 56, Issue:1-6 Spec N Topics: Adenocarcinoma; Androgens; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Male; Mice; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nitriles; Triazoles; Tumor Cells, Cultured	1996
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer. Journal of surgical oncology, 1997, Volume: 66, Issue:3 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles	1997
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women. The Netherlands journal of medicine, 1999, Volume: 55, Issue:2 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles	1999
[Aromatase inhibitors]. Bulletin du cancer, 1999, Volume: 86, Issue:10 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles	1999
Aromatase inhibitors and their application in breast cancer treatment. Steroids, 2000, Volume: 65, Issue:4* Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Mice; Nitriles; Tamoxifen; Triazoles	2000
Drug and hormone interactions of aromatase inhibitors. Endocrine-related cancer, 1999, Volume: 6, Issue:2 Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Enzyme Inhibitors; Estrogens; Fadrozole; Female; Humans; Letrozole; Male; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Sensitivity and Specificity; Tamoxifen; Triazoles	1999
Aromatase inhibitors and their use in the sequential setting. Endocrine-related cancer, 1999, Volume: 6, Issue:2 Topics: Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles	1999
Use of aromatase inhibitors in breast carcinoma. Endocrine-related cancer, 1999, Volume: 6, Issue:1 Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles	1999
Steroidal aromatase inhibitors in elderly patients. Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:2 Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles	2000
[Preclinical evaluation of aromatase inhibitors antitumor activity]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles	2000
[Aromatase inhibitors: pharmacological aspects]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles	2000
[Aromatase inhibitors: a review of clinical trials]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles	2000
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9 Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting	2001
[Aromatase inhibitors in adjuvant setting in breast cancer]. Bulletin du cancer, 2004, Dec-01, Volume: 91 Suppl 4 Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Menopause; Nitriles; Triazoles	2004
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials. Cancer, 2005, Oct-01, Volume: 104, Issue:7 Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles	2005
Use of aromatase inhibitors in children with short stature. Pediatric endocrinology reviews : PER, 2004, Volume: 2, Issue:1 Topics: Adult; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Body Height; Child; Estrogens; Female; Growth Disorders; Humans; Letrozole; Male; Musculoskeletal System; Nitriles; Triazoles	2004
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18 Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles	2006
Aromatase inhibitors: past, present and future in breast cancer therapy. Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles	2008
[Progress in study of the structure, catalytic mechanism and inhibitors of aromatase]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:1 Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Catalysis; Coumarins; Estrogens; Flavonoids; Humans; Inhibitory Concentration 50; Letrozole; Nitriles; Sesquiterpenes; Structure-Activity Relationship; Triazoles; Xanthones	2012

Trials

8 trial(s) available for letrozole and androstenedione

Article	Year
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in healthy postmenopausal women. The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Aged; Aldosterone; Androstenedione; Aromatase Inhibitors; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Letrozole; Luteinizing Hormone; Male; Menopause; Middle Aged; Nitriles; Random Allocation; Testosterone; Thyrotropin; Time Factors; Triazoles	1993
In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:12 Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Nitriles; Postmenopause; Triazoles	1995
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast cancer research and treatment, 2003, Volume: 79, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles	2003
Superiority of gas chromatography/tandem mass spectrometry assay (GC/MS/MS) for estradiol for monitoring of aromatase inhibitor therapy. Steroids, 2007, Volume: 72, Issue:8 Topics: Androstenedione; Aromatase Inhibitors; Biological Assay; Breast Neoplasms; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Letrozole; Nitriles; Placebos; Postmenopause; Radioimmunoassay; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazoles	2007
Phase III, double-blind, controlled trial of atamestane plus toremifene compared with letrozole in postmenopausal women with advanced receptor-positive breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Nov-01, Volume: 25, Issue:31 Topics: Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Steroid; Toremifene; Triazoles	2007
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy. Breast cancer research and treatment, 2011, Volume: 130, Issue:2 Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Female; Humans; Letrozole; Middle Aged; Musculoskeletal Pain; Nitriles; Testosterone; Triazoles	2011
Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial. Reproductive biomedicine online, 2011, Volume: 23, Issue:3 Topics: Adult; Androstenedione; Anti-Mullerian Hormone; Aromatase Inhibitors; Estradiol; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Humans; Letrozole; Menotropins; Nitriles; Ovarian Follicle; Pregnancy; Pregnancy Rate; Triazoles	2011
Effects of letrozole cotreatment on endocrinology and follicle development in women undergoing ovarian stimulation in an antagonist protocol. Human reproduction (Oxford, England), 2022, 06-30, Volume: 37, Issue:7 Topics: Androgens; Androstenedione; Double-Blind Method; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Letrozole; Ovulation Induction; Progesterone; Testosterone	2022

Other Studies

23 other study(ies) available for letrozole and androstenedione

Article	Year
Effect of aromatase inhibitors on growth of mammary tumors in a nude mouse model. Cancer research, 1995, Jul-15, Volume: 55, Issue:14 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Fadrozole; Female; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Organ Size; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles; Uterus	1995
Changes induced by treatment with aromatase inhibitors in testicular Leydig cells of rats and dogs. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:3 Topics: Androstenedione; Animals; Aromatase Inhibitors; Dogs; Genitalia, Male; Letrozole; Leydig Cells; Male; Nitriles; Rats; Species Specificity; Triazoles	1994
Paradoxical effect of an aromatase inhibitor, CGS 20267, on aromatase activity in guinea pig brain. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:4 Topics: Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Brain; Enzyme Inhibitors; Estradiol; Estrone; Guinea Pigs; Kinetics; Letrozole; Male; Microsomes; Nitriles; Orchiectomy; Testosterone; Triazoles	1996
Oestrogen formation in breast: clinical and biological importance. The Journal of endocrinology, 1996, Volume: 150 Suppl Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Mice; Mice, Nude; Nitriles; Signal Transduction; Transfection; Triazoles; Tumor Cells, Cultured	1996
Aromatase inhibitors come of age. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles	1997
Tamoxifen-resistant fibroblast growth factor-transfected MCF-7 cells are cross-resistant in vivo to the antiestrogen ICI 182,780 and two aromatase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:3 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fibroblast Growth Factors; Fulvestrant; Humans; Letrozole; Luciferases; Mice; Mice, Nude; Nitriles; Ovariectomy; Polymerase Chain Reaction; Receptors, Progesterone; Recombinant Fusion Proteins; RNA, Messenger; Tamoxifen; Transcription, Genetic; Transfection; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured	1998
The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity. The Journal of steroid biochemistry and molecular biology, 1998, Volume: 67, Issue:4 Topics: Anastrozole; Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; Cell Division; Cells, Cultured; Choriocarcinoma; DNA Primers; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fibroblasts; Fulvestrant; Humans; Letrozole; Microsomes; Nitriles; Placenta; RNA, Messenger; Triazoles; Tumor Cells, Cultured	1998
[Metabolism of the androgenic precursor androstenedione and effects of aromatase inhibitors in cultured blood lymphocytes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1998, Volume: 84, Issue:11 Topics: Adolescent; Adult; Age Factors; Aged; Androstenedione; Aromatase Inhibitors; Bucladesine; Cells, Cultured; Dexamethasone; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Lymphocytes; Middle Aged; Nitriles; Triazoles	1998
Developmental regulation of morphological differentiation of placental villous trophoblast in the baboon. Placenta, 2001, Volume: 22, Issue:4 Topics: Androstenedione; Animals; Aromatase Inhibitors; Bromodeoxyuridine; Cell Differentiation; Enzyme Inhibitors; Estradiol; Estrogens; Female; Ki-67 Antigen; Letrozole; Nitriles; Papio; Placenta; Pregnancy; Triazoles; Trophoblasts	2001
Formestane, a steroidal aromatase inhibitor after failure of non-steroidal aromatase inhibitors (anastrozole and letrozole): is a clinical benefit still achievable? Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:11 Topics: Adult; Aged; Anastrozole; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Retrospective Studies; Treatment Failure; Triazoles	2001
Developmental regulation of baboon fetal ovarian maturation by estrogen. Biology of reproduction, 2002, Volume: 67, Issue:4 Topics: Androstenedione; Animals; Aromatase Inhibitors; Enzyme Inhibitors; Epithelium; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fetal Blood; Gestational Age; Letrozole; Mesoderm; Nitriles; Organ Size; Ovary; Papio; Pregnancy; Receptors, Estrogen; Testosterone; Triazoles	2002
Characterization of stable human aromatase expressed in E. coli. Steroids, 2004, Volume: 69, Issue:4 Topics: Amino Acid Sequence; Androstenedione; Arginine; Aromatase; Aromatase Inhibitors; Cell Membrane; Chaperonin 10; Chaperonin 60; Chloramphenicol; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Stability; Escherichia coli; Estradiol; Estrone; Fadrozole; Gene Expression; Humans; Letrozole; Molecular Sequence Data; Nitriles; Polymorphism, Genetic; Protein Structure, Secondary; Protein Synthesis Inhibitors; Recombinant Proteins; Solubility; Testosterone; Triazoles	2004
Endogenous aromatization of testosterone results in growth stimulation of the human MCF-7 breast cancer cell line. The Journal of steroid biochemistry and molecular biology, 2005, Volume: 93, Issue:1 Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Culture Media; Dose-Response Relationship, Drug; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; Letrozole; Nitriles; Receptors, Estrogen; Testosterone; Triazoles; Tumor Cells, Cultured	2005
ErbB receptor signaling and therapeutic resistance to aromatase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Feb-01, Volume: 12, Issue:3 Pt 2 Topics: Acetyltransferases; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Corticosterone; Drug Resistance, Neoplasm; Female; Histone Acetyltransferases; Humans; Letrozole; Nitriles; Nuclear Receptor Coactivator 3; Oncogene Proteins; Promoter Regions, Genetic; Receptor, ErbB-2; Receptors, Estrogen; Signal Transduction; Trans-Activators; Transcriptional Activation; Triazoles	2006
Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole. Cancer research, 2006, Aug-01, Volume: 66, Issue:15 Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Aromatase; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Dihydrotestosterone; Estradiol; Estrogen Receptor alpha; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Proto-Oncogene Proteins c-bcl-2; Receptors, Androgen; RNA, Small Interfering; Transfection; Triazoles	2006
The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model. Breast cancer research and treatment, 2007, Volume: 103, Issue:3 Topics: Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Female; Humans; Letrozole; Lipids; Models, Chemical; Nitriles; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Toremifene; Triazoles; Uterus	2007
Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol "in situ" production. Journal of cellular physiology, 2007, Volume: 211, Issue:2 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Chromatin Immunoprecipitation; DNA; Electrophoretic Mobility Shift Assay; Estradiol; Estrogen Receptor alpha; Fas Ligand Protein; Follicle Stimulating Hormone; Genes, Reporter; HeLa Cells; Humans; Immune Tolerance; Letrozole; Luciferases; Male; Mice; Mice, Inbred BALB C; Mutation; Nitriles; Promoter Regions, Genetic; RNA, Messenger; Sertoli Cells; Sp1 Transcription Factor; Transcription, Genetic; Transfection; Triazoles; Up-Regulation	2007
Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-01, Volume: 13, Issue:9 Topics: Androstadienes; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Estrogen Receptor Modulators; Humans; Letrozole; Mice; Mice, Nude; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Tamoxifen; Triazoles; Wortmannin	2007
Binding features of steroidal and nonsteroidal inhibitors. Steroids, 2011, Volume: 76, Issue:8 Topics: Amino Acids; Androgens; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Catalytic Domain; Estrogens; Estrone; Female; Humans; Letrozole; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Neoplasms, Hormone-Dependent; Nitriles; Protein Conformation; Structure-Activity Relationship; Triazoles	2011
Aromatase activity after a short-course of letrozole administration in adult men at sea level and at high altitude (with or without excessive erythrocytosis). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:2 Topics: Adult; Altitude; Androstenedione; Aromatase; Aromatase Inhibitors; Cohort Studies; Dehydroepiandrosterone Sulfate; Estradiol; Hemoglobins; Humans; Letrozole; Male; Middle Aged; Nitriles; Oximetry; Peru; Polycythemia; Prospective Studies; Statistics, Nonparametric; Testosterone; Triazoles	2012
AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-15, Volume: 18, Issue:12 Topics: Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Letrozole; MAP Kinase Signaling System; Neoplasm Recurrence, Local; Nitriles; Nuclear Receptor Coactivator 3; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Transcription, Genetic; Trefoil Factor-1; Triazoles; Tumor Suppressor Proteins; Up-Regulation	2012
Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells. Oncogene, 2013, Oct-31, Volume: 32, Issue:44 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; CD24 Antigen; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Estradiol; Estrogen Receptor alpha; Female; Gene Expression; Humans; Hyaluronan Receptors; Letrozole; Neoplastic Stem Cells; Nitriles; RNA, Messenger; Spheroids, Cellular; Triazoles	2013
Estrogens Regulate Placental Angiogenesis in Horses. International journal of molecular sciences, 2021, Nov-09, Volume: 22, Issue:22 Topics: Androstenedione; Angiopoietin-1; Animals; Aromatase; Estrogens; Female; Gene Expression Regulation, Developmental; Horses; Letrozole; Maternal-Fetal Relations; Neovascularization, Physiologic; Placenta; Pregnancy; Pregnancy Trimester, First; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Testosterone; Vascular Endothelial Growth Factor A	2021