letrozole and abemaciclib

letrozole has been researched along with abemaciclib in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (35.29)24.3611
2020's11 (64.71)2.80

Authors

AuthorsStudies
Akıncı, MB; Bilgin, B; Sendur, MAN; Şener Dede, D; Yalçın, B1
Messina, C; Messina, M; Zanardi, E1
Barriga, S; Bourayou, N; Campone, M; Chen, SC; Di Leo, A; Forrester, T; Freedman, OC; Frenzel, M; Garnica Jaliffe, G; Goetz, MP; Huober, J; Manso, L; Paluch-Shimon, S; Park, IH; Smith, IC; Sohn, J; Toi, M; Trédan, O1
Afghahi, A; Diamond, JR; Shagisultanova, E; Weiss, J1
Chen, Q; Dai, Y; Guo, Q; Lin, X; Xu, R; Ye, L; Zhang, Y1
Arpino, G; Bachelot, T; Cristofanilli, M; De Laurentiis, M; De Placido, P; De Placido, S; Del Mastro, L; Generali, D; Giordano, A; Giuliano, M; Jerusalem, G; Milani, M; Pistilli, B; Prat, A; Puglisi, F; Rognoni, C; Schettini, F; Thomas, G; Venturini, S1
Dhakne, P; Sahu, AK; Sengupta, P; Sharma, MK1
Canova, C; Klausner, G; Troussier, I1
Agostinetto, E; de Azambuja, E; Debien, V; Lambertini, M; Marta, GN; Piccart-Gebhart, M1
André, VAM; Chen, SC; Enatsu, S; Goetz, MP; Hae Park, I; Hardebeck, MC; Im, SA; Inoue, K; Iwata, H; Masuda, N; Sakaguchi, S; Sledge, GW; Sohn, J; Toi, M; Turner, PK1
Ashkenazy, N; Correa, ZM; Goduni, L; Hansen, E; Harbour, JW; Soyano-Muller, A1
Goetz, MP; Kawaguchi, T; Mori, J; Takahashi, M; Tanizawa, Y; Toi, M; Tokunaga, E; van der Walt, JS1
Bouberhan, S; Bowes, B; Campos, S; Castro, C; Cheng, SC; Hayes, M; Horowitz, N; Kolin, DL; Konstantinopoulos, PA; Krasner, C; Lee, EK; Liu, JF; Matulonis, UA; Needham, H; Penson, RT; Polak, M; Sawyer, H; Shea, M; Wright, AA; Xiong, N; Yeku, O1
Damgacioglu, H; Deshmukh, AA; Masurkar, PP; Trivedi, MV1
Kamo, N; Konishi, J; Nozaki, Y; Tanaka, N; Yamamuro, M1
Hayashi, M; Hirata, A; Kimura, K; Morita, S; Takashima, Y; Terasawa, R1
Aogi, K; Futamura, M; Hosonaga, M; Imamura, CK; Iwasa, T; Iwata, H; Kawabata, H; Masuda, J; Masuda, N; Matsumoto, K; Miura, S; Mukohara, T; Sakai, H; Takahashi, M; Takano, T; Tanabe, Y; Tomioka, N; Tsurutani, J; Yamochi, T; Yasojima, H; Yoshimura, K1

Reviews

5 review(s) available for letrozole and abemaciclib

ArticleYear
A current and comprehensive review of cyclin-dependent kinase inhibitors for the treatment of metastatic breast cancer.
    Current medical research and opinion, 2017, Volume: 33, Issue:9

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinase 4; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Randomized Controlled Trials as Topic; Triazoles

2017
Risks and benefits from CDK inhibitors for advanced HR+ Her 2- breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 12-01, Volume: 28, Issue:12

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinases; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Risk Assessment; Triazoles

2017
Comparative Efficacy of CDK4/6 Inhibitors Plus Aromatase Inhibitors Versus Fulvestrant for the First-Line Treatment of Hormone Receptor-Positive Advanced Breast Cancer: A Network Meta-Analysis.
    Targeted oncology, 2019, Volume: 14, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Fulvestrant; Humans; Letrozole; Network Meta-Analysis; Piperazines; Purines; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2019
Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis.
    The Lancet. Oncology, 2019, Volume: 20, Issue:10

    Topics: Aminopyridines; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bevacizumab; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Everolimus; Female; Fulvestrant; Humans; Letrozole; Network Meta-Analysis; Paclitaxel; Piperazines; Postmenopause; Progression-Free Survival; Purines; Pyridines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2019
CDK4/6 and PI3K inhibitors: A new promise for patients with HER2-positive breast cancer.
    European journal of clinical investigation, 2021, Volume: 51, Issue:7

    Topics: Aminopyridines; Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Immunological; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Fulvestrant; Humans; Letrozole; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Trastuzumab

2021

Trials

5 trial(s) available for letrozole and abemaciclib

ArticleYear
MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Nov-10, Volume: 35, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzimidazoles; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptor, ErbB-2; Survival Rate; Treatment Outcome; Triazoles

2017
Abemaciclib in combination with endocrine therapy for East Asian patients with HR+, HER2- advanced breast cancer: MONARCH 2 & 3 trials.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Aminopyridines; Anastrozole; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Fulvestrant; Humans; Letrozole; Neutropenia; Receptor, ErbB-2; Treatment Outcome

2021
Japanese subgroup analysis of the phase 3 MONARCH 3 study of abemaciclib as initial therapy for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer.
    Breast cancer (Tokyo, Japan), 2022, Volume: 29, Issue:1

    Topics: Aged; Aminopyridines; Anastrozole; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Female; Humans; Japan; Letrozole; Middle Aged; Progression-Free Survival; Quality of Life; Receptors, Progesterone

2022
A Phase II, Two-Stage Study of Letrozole and Abemaciclib in Estrogen Receptor-Positive Recurrent Endometrial Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 01-20, Volume: 41, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Endometrial Neoplasms; Female; Humans; Letrozole; Ligands; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Receptors, Estrogen; Treatment Outcome

2023
Efficacy, safety, and biomarker analysis of nivolumab in combination with abemaciclib plus endocrine therapy in patients with HR-positive HER2-negative metastatic breast cancer: a phase II study (WJOG11418B NEWFLAME trial).
    Journal for immunotherapy of cancer, 2023, Volume: 11, Issue:9

    Topics: Aminopyridines; Antibodies; Benzimidazoles; Breast Neoplasms; Female; Humans; Letrozole; Nivolumab

2023

Other Studies

7 other study(ies) available for letrozole and abemaciclib

ArticleYear
Approaching Use of CDK4/6 Inhibitors in Metastatic HR+, HER2- Breast Cancer.
    Oncology (Williston Park, N.Y.), 2018, Oct-15, Volume: 32, Issue:10

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Carcinoma, Lobular; Colonic Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2018
Simultaneous quantification of abemaciclib and letrozole in rat plasma: method development, validation and pharmacokinetic application.
    Biomedical chromatography : BMC, 2020, Volume: 34, Issue:6

    Topics: Aminopyridines; Animals; Benzimidazoles; Chromatography, High Pressure Liquid; Female; Letrozole; Limit of Detection; Linear Models; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2020
Complete response of leptomeningeal carcinomatosis secondary to breast cancer.
    Breast (Edinburgh, Scotland), 2020, Volume: 54

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Female; Humans; Letrozole; Meningeal Carcinomatosis; Middle Aged; Radiotherapy, Adjuvant

2020
IRIS METASTASIS FROM BREAST CANCER SUCCESSFULLY TREATED WITH ABEMACICLIB AND LETROZOLE.
    Retinal cases & brief reports, 2023, Mar-01, Volume: 17, Issue:2

    Topics: Breast Neoplasms; Female; Humans; Iris Neoplasms; Letrozole; Retrospective Studies

2023
Cost Effectiveness of CDK4/6 Inhibitors in the First-Line Treatment of HR+/HER2- Metastatic Breast Cancer in Postmenopausal Women in the USA.
    PharmacoEconomics, 2023, Volume: 41, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cost-Effectiveness Analysis; Cyclin-Dependent Kinase 4; Female; Humans; Letrozole; Medicare; Postmenopause; Receptor, ErbB-2; United States

2023
[Chemotherapy-Resistant Breast Cancer and Carcinomatous Pleuritis Successfully Treated with Abemaciclib plus Letrozole Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Female; Humans; Letrozole; Paclitaxel; Pleurisy

2023
[ESR1 Mutation-Positive Recurrent Breast Cancer Successfully Treated with Letrozole plus Abemaciclib].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:8

    Topics: Aminopyridines; Breast Neoplasms; Female; Humans; Letrozole; Mutation

2023