Compounds > lestaurtinib
Page last updated: 2024-09-03

lestaurtinib and urmc-099

lestaurtinib has been researched along with urmc-099 in 1 studies

Compound Research Comparison

Studies
(lestaurtinib)		Trials
(lestaurtinib)		Recent Studies (post-2010)
(lestaurtinib)		Studies
(urmc-099)		Trials
(urmc-099)		Recent Studies (post-2010) (urmc-099)
124126321020

Protein Interaction Comparison

ProteinTaxonomylestaurtinib (IC50)urmc-099 (IC50)
Serine/threonine-protein kinase Sgk1Homo sapiens (human)0.201
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)0.257
Aurora kinase AHomo sapiens (human)0.108
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)0.591
5'-AMP-activated protein kinase subunit beta-2Homo sapiens (human)1.512
Rho-associated protein kinase 2Homo sapiens (human)0.111
Tyrosine-protein kinase ABL1Homo sapiens (human)0.0049
High affinity nerve growth factor receptorHomo sapiens (human)0.085
Insulin receptorHomo sapiens (human)0.2
Tyrosine-protein kinase LckHomo sapiens (human)0.333
Cyclin-dependent kinase 1Homo sapiens (human)1.125
Insulin-like growth factor 1 receptorHomo sapiens (human)0.307
Hepatocyte growth factor receptorHomo sapiens (human)0.177
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)4.33
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.039
Cyclin-dependent kinase 2Homo sapiens (human)1.18
Mitogen-activated protein kinase 1Homo sapiens (human)6.29
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.282
Tyrosine-protein kinase ZAP-70Homo sapiens (human)5.05
Tyrosine-protein kinase SYKHomo sapiens (human)0.731
Mitogen-activated protein kinase 8Homo sapiens (human)3.24
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)1.512
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)1.512
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)0.019
Protein delta homolog 1Homo sapiens (human)0.15
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)0.042
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)1.512
Rho-associated protein kinase 1Homo sapiens (human)1.03
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)0.014
BDNF/NT-3 growth factors receptorHomo sapiens (human)0.217
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.011
Mitogen-activated protein kinase kinase kinase 11Mus musculus (house mouse)0.46
Aurora kinase BHomo sapiens (human)0.123
5'-AMP-activated protein kinase subunit gamma-3Homo sapiens (human)1.512
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)1.512
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)0.0052
Aurora kinase CHomo sapiens (human)0.29
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)0.661
5'-AMP-activated protein kinase subunit beta-1Homo sapiens (human)1.512

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dewhurst, S; Gelbard, HA; Goodfellow, VS; Loweth, CJ; Marker, DF; Nguyen, T; Polesskaya, O; Pollack, S; Ravula, SB; Sheppard, D; Todd, DE; Wiemann, T; Xu, Y1

Other Studies

1 other study(ies) available for lestaurtinib and urmc-099

ArticleYear
Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Blood-Brain Barrier; Brain; Carbazoles; Cells, Cultured; Cognition Disorders; Drug Discovery; HIV Infections; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinase Kinase 11; Models, Chemical; Molecular Structure; Monocytes; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha

2013