lestaurtinib has been researched along with 3,9-bis((ethylthio)methyl)-k-252a in 1 studies
| Studies (lestaurtinib) | Trials (lestaurtinib) | Recent Studies (post-2010) (lestaurtinib) | Studies (3,9-bis((ethylthio)methyl)-k-252a) | Trials (3,9-bis((ethylthio)methyl)-k-252a) | Recent Studies (post-2010) (3,9-bis((ethylthio)methyl)-k-252a) |
|---|---|---|---|---|---|
| 124 | 12 | 63 | 73 | 4 | 9 |
| Protein | Taxonomy | lestaurtinib (IC50) | 3,9-bis((ethylthio)methyl)-k-252a (IC50) |
|---|---|---|---|
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | 0.209 | |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | 0.039 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 0.043 | |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | 0.0413 | |
| Protein delta homolog 1 | Homo sapiens (human) | 0.114 | |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | 0.0412 | |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | 0.0364 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dewhurst, S; Gelbard, HA; Goodfellow, VS; Loweth, CJ; Marker, DF; Nguyen, T; Polesskaya, O; Pollack, S; Ravula, SB; Sheppard, D; Todd, DE; Wiemann, T; Xu, Y | 1 |
1 other study(ies) available for lestaurtinib and 3,9-bis((ethylthio)methyl)-k-252a
| Article | Year |
|---|---|
Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Blood-Brain Barrier; Brain; Carbazoles; Cells, Cultured; Cognition Disorders; Drug Discovery; HIV Infections; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinase Kinase 11; Models, Chemical; Molecular Structure; Monocytes; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha | 2013 |