leojaponin has been researched along with leonurine* in 1 studies
1 other study(ies) available for leojaponin and leonurine
| Article | Year |
|---|---|
Chemical composition and evaluation of prolyl oligopeptidase and acetylcholinesterase inhibitory activities of Leonurus Sibiricus L. from Brazil.
Chemical investigation of the aerial parts of Leonurus sibiricus L. used in Brazilian folk medicine led to the identification of the following constituents: the labdane-type diterpenoid leojaponin, the phytosterols β-sitosterol and β-sitosterol glucoside and the alkaloid leonurine. The crude extracts obtained from methanol and methanol/1% HCl and pure compounds isolated from L. sibirius were investigated as acetylcholinesterase (AChE) and prolyl oligopeptidase (POP) inhibitors. Extracts obtained by maceration were active against POP (53-58%), but showed weak activity against AChE. The isolated leojaponin and leonurine were evaluated as POP inhibitors. Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Diterpenes; Gallic Acid; Leonurus; Plant Extracts; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors | 2017 |