lenvatinib has been researched along with flubendazole* in 1 studies
1 other study(ies) available for lenvatinib and flubendazole
Article | Year |
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Drug Repurposing Flubendazole to Suppress Tumorigenicity via PCSK9-dependent Inhibition and Potentiate Lenvatinib Therapy for Hepatocellular Carcinoma.
Hepatocellular carcinoma (HCC) is one of the most lethal malignant cancers across the world. It has a poor prognosis and lacks effective therapies, especially for patients with advanced-stage cancer, indicating an urgent need for new therapies and novel therapeutic targets. Here, by screening the U.S. Food and Drug Administration drug library against HCC cell lines, we identified that flubendazole, a traditional anthelmintic drug, could prominently suppress HCC cells Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Repositioning; Hedgehog Proteins; Humans; Liver Neoplasms; Proprotein Convertase 9 | 2023 |