Compounds > lenalidomide
Page last updated: 2024-09-05

lenalidomide and pazopanib

lenalidomide has been researched along with pazopanib in 4 studies

Compound Research Comparison

Studies
(lenalidomide)		Trials
(lenalidomide)		Recent Studies (post-2010)
(lenalidomide)		Studies
(pazopanib)		Trials
(pazopanib)		Recent Studies (post-2010) (pazopanib)
3,5327252,8501,1472371,028

Protein Interaction Comparison

ProteinTaxonomylenalidomide (IC50)pazopanib (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)8.1
Tyrosine-protein kinase ABL1Homo sapiens (human)2.2043
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.21
Cytochrome P450 3A4Homo sapiens (human)0.03
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0837
Cytochrome P450 2D6Homo sapiens (human)0.03
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.0887
Fibroblast growth factor receptor 1Homo sapiens (human)0.1477
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.071
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.032
Fibroblast growth factor receptor 2Homo sapiens (human)0.14
AcetylcholinesteraseHomo sapiens (human)0.93
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.0467
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.4929
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)0.873
Discoidin domain-containing receptor 2Homo sapiens (human)0.0505
Receptor protein-tyrosine kinase Homo sapiens (human)2.2043

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arango, BA; Cohen, EE; Perez, CA; Raez, LE; Santos, ES1

Reviews

2 review(s) available for lenalidomide and pazopanib

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Novel molecular targeted therapies for refractory thyroid cancer.
    Head & neck, 2012, Volume: 34, Issue:5

    Topics: Angiogenesis Inhibitors; Anilides; Antineoplastic Agents; Axitinib; Benzamides; Benzenesulfonates; Benzoquinones; Bibenzyls; Boronic Acids; Bortezomib; Depsipeptides; ErbB Receptors; Gefitinib; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Imatinib Mesylate; Imidazoles; Indazoles; Indoles; Lactams, Macrocyclic; Lenalidomide; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thalidomide; Thyroid Neoplasms; Valproic Acid; Vorinostat

2012

Other Studies

2 other study(ies) available for lenalidomide and pazopanib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013