Page last updated: 2024-09-05

lenalidomide and nelfinavir

lenalidomide has been researched along with nelfinavir in 3 studies

Compound Research Comparison

Studies (lenalidomide)	Trials (lenalidomide)	Recent Studies (post-2010) (lenalidomide)	Studies (nelfinavir)	Trials (nelfinavir)	Recent Studies (post-2010) (nelfinavir)
3,532	725	2,850	1,240	230	240

Protein Interaction Comparison

Protein	Taxonomy	nelfinavir (IC50)
Tyrosine-protein kinase Fyn	Homo sapiens (human)	7.971
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	8.852
ATP-dependent translocase ABCB1	Homo sapiens (human)	3.3938
Cytochrome P450 3A4	Homo sapiens (human)	1.275
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2.3
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	8.852
Protease	Human immunodeficiency virus 1	0.53
Protease	Human immunodeficiency virus 1	0.0054

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Besse, L; Driessen, C; Hess, D; Hitz, F; Kraus, M; Mey, U; Novak, U; Pabst, T; Rondeau, S; Samaras, P; Seipel, K; Silzle, T; Stüdeli, S; Vilei, SB	1

Reviews

1 review(s) available for lenalidomide and nelfinavir

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for lenalidomide and nelfinavir

Article	Year
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10). Blood cancer journal, 2019, 08-27, Volume: 9, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Dexamethasone; Female; HIV Protease Inhibitors; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Nelfinavir	2019

Other Studies

1 other study(ies) available for lenalidomide and nelfinavir

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013

Article

Year

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013