lecimibide has been researched along with urea in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (75.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harte, RA; Jackson, B; Suckling, KE; Yeaman, SJ | 2 |
| Brogdon, B; Lai, CM; Pieniaszek, HJ; Quon, CY | 1 |
| Billheimer, JT; Gillies, PJ; Higley, CA; Johnson, AL; Maduskuie, TP; Pennev, P; Robinson, CS; Wexler, RR; Wilde, RG | 1 |
| Connell, JM; Crouse, JR; Gillies, PJ; Hainer, JW; Hunt, TL; Jenkins, RM; Livak, KJ; Shand, DL; Terry, JG; Zyruk, H | 1 |
| Barrett, PH; Billheimer, JT; Gillies, PJ; Huff, MW; Telford, DE | 1 |
| Anderson, M; Bousley, RF; Hamelehle, KL; Homan, R; Julian, TN; Krause, BR; Picard, JA; Rashidbaigi, ZA; Sliskovic, DR; Stanfield, RL | 1 |
| Botham, KM; Hoang, VQ; Pearce, NJ; Suckling, KE | 1 |
| Barrett, PH; Burnett, JR; Huff, MW; Kleinstiver, SJ; Telford, DE; Wilcox, LJ | 1 |
| Chao, YS; Detmers, PA; Hernandez, M; Kim, D; Montenegro, J; Sparrow, C; Steiner, M; Wright, SD | 1 |
| Horiuchi, S; Miyazaki, A | 1 |
| Brown, WJ; Schmidt, JA | 1 |
1 review(s) available for lecimibide and urea
| Article | Year |
|---|---|
[ACAT inhibitors].
Topics: Anilides; Animals; Arteriosclerosis; Benzofurans; Cholesterol Esters; Cyclohexanes; Dioxanes; Endothelium, Vascular; Humans; Hyperlipidemias; Imidazoles; Intestine, Small; Liver; Organ Specificity; Phenylurea Compounds; Sterol O-Acyltransferase; Urea | 2001 |
1 trial(s) available for lecimibide and urea
| Article | Year |
|---|---|
Effect of the acyl-CoA:cholesterol acyltransferase inhibitor DuP 128 on cholesterol absorption and serum cholesterol in humans.
Topics: Adult; Base Sequence; Carbon Radioisotopes; Cholesterol; Humans; Imidazoles; Intestinal Absorption; Male; Molecular Sequence Data; Sterol O-Acyltransferase; Tritium; Urea | 1994 |
10 other study(ies) available for lecimibide and urea
| Article | Year |
|---|---|
Effect of membrane environment on inhibition of acyl-CoA:cholesterol acyltransferase by a range of synthetic inhibitors.
Topics: Anilides; Animals; Cholesterol; Detergents; Enzyme Inhibitors; Esterification; Imidazoles; Liposomes; Male; Microsomes, Liver; Oleic Acid; Oleic Acids; Phenylurea Compounds; Phosphatidylcholines; Rats; Rats, Wistar; Solubility; Sterol O-Acyltransferase; Tumor Cells, Cultured; Urea | 1995 |
Determination of DuP 128, an ACAT inhibitor and its sulphoxide and sulphone metabolites in human plasma by liquid chromatography.
Topics: Administration, Oral; Anticholesteremic Agents; Chromatography, High Pressure Liquid; Fluorescence; Humans; Imidazoles; Male; Sterol O-Acyltransferase; Sulfones; Sulfoxides; Urea | 1994 |
Acyl CoA:cholesterol acyltransferase (ACAT) inhibitors: synthesis and structure-activity relationship studies of a new series of trisubstituted imidazoles.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Cricetinae; Imidazoles; Male; Mesocricetus; Microsomes, Liver; Molecular Structure; Rats; Sterol O-Acyltransferase; Structure-Activity Relationship; Urea | 1994 |
Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet.
Topics: Animals; Apolipoproteins B; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Imidazoles; Kinetics; Lipoproteins, VLDL; Liver; Sterol O-Acyltransferase; Swine; Swine, Miniature; Triglycerides; Urea | 1994 |
Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity.
Topics: Absorption; Animals; Anticholesteremic Agents; Biological Availability; Carbamates; Cholesterol; Cholesterol Esters; Hydrogen-Ion Concentration; Hypercholesterolemia; Imidazoles; Lipids; Liver; Microsomes, Liver; Phenylurea Compounds; Rats; Solubility; Sterol O-Acyltransferase; Urea; Water | 1994 |
The regulation of bile acid synthesis in cultured hamster hepatocytes.
Topics: Animals; Bile Acids and Salts; Cells, Cultured; Chenodeoxycholic Acid; Cholestyramine Resin; Cholic Acid; Cholic Acids; Cricetinae; Hydroxycholesterols; Imidazoles; Lipoproteins, LDL; Liver; Lovastatin; Male; Mesocricetus; Mevalonic Acid; Taurocholic Acid; Urea | 1993 |
Differences in the potency of ACAT inhibitors in two assay systems.
Topics: Acyl Coenzyme A; Anilides; Animals; Carbon Radioisotopes; Imidazoles; Indicators and Reagents; Kinetics; Male; Microsomes, Liver; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sterol O-Acyltransferase; Urea | 1993 |
Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Cholesterol, Dietary; Dietary Fats; Down-Regulation; Enzyme Inhibitors; Imidazoles; Intestines; Lipoproteins, VLDL; Liver; Sterol O-Acyltransferase; Swine; Swine, Miniature; Urea | 1998 |
Intestinal absorption of cholesterol is mediated by a saturable, inhibitable transporter.
Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Binding Sites; Biological Transport; Cholesterol, Dietary; Cricetinae; Dogs; Down-Regulation; Enzyme Inhibitors; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Male; Mesocricetus; Mice; Microvilli; Molecular Structure; Rats; Saponins; Simvastatin; Species Specificity; Spirostans; Structure-Activity Relationship; Tritium; Urea | 2000 |
Use of acyltransferase inhibitors to block vesicular traffic between the ER and Golgi complex.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyltransferases; Anilides; Animals; Cells, Cultured; COP-Coated Vesicles; Endoplasmic Reticulum; Golgi Apparatus; Imidazoles; Intracellular Membranes; Protein Transport; Rats; Sterol O-Acyltransferase; Urea | 2005 |