lead has been researched along with metallothionein in 143 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (14.69) | 18.7374 |
| 1990's | 15 (10.49) | 18.2507 |
| 2000's | 25 (17.48) | 29.6817 |
| 2010's | 70 (48.95) | 24.3611 |
| 2020's | 12 (8.39) | 2.80 |
| Authors | Studies |
|---|---|
| Klaassen, CD | 1 |
| Sharma, RP; Street, JC; Verma, MP | 1 |
| Piper, WN; Van Lier, RB | 1 |
| Evans, SW; Hay, A; Orupabo, I | 1 |
| Aposhian, HV; Nelson, DL; Perry, DF; Zheng, W | 1 |
| Kershaw, WC; Klaassen, CD; Liu, J | 1 |
| Bhatnagar, MK; Jordan, SA; Prasada Rao, PV | 1 |
| Abrahams, I; Bremner, I; Diakun, GP; Garner, CD; Hasnain, SS; Ross, I; Vasak, M | 1 |
| Abel, J; Behrendt, H; Dehnen, W; Gleichmann, E; Schlipköter, HW; Seemayer, N; Wiegand, H | 1 |
| Chandra, RK; Chowdhury, BA | 1 |
| Fowler, BA; Goering, PL | 4 |
| Ikebuchi, H; Sawada, J; Suzuki, K; Terao, T; Teshima, R; Yamane, Y | 1 |
| Endo, S; Hikichi, H; Kaneta, M; Sugiyama, N | 1 |
| Hall, PW; Hines, JD; Vacca, CV | 1 |
| Ikebuchi, H; Suzuki, K; Terao, T; Teshima, R; Yamane, Y | 1 |
| Maitani, T; Suzuki, KT; Watahiki, A | 1 |
| Ariyoshi, T; Arizono, K; Ito, T; Ota, S | 1 |
| Cherian, MG | 1 |
| Hayashi, Y; Mikami, E | 1 |
| Goyer, RA | 1 |
| Bernard, A; Buchet, JP; Lauwerys, R; Mohammed-Brahim, B | 1 |
| Abdullah, R; Kodati, VR; Mehra, RK | 1 |
| Kaji, T; Kozuka, H; Mishima, A; Sakamoto, M; Suzuki, M; Yamamoto, C | 1 |
| Jain, VK; Khandelwal, S; Mathur, N; Tandon, SK | 2 |
| Angle, CR; Swanson, SA; Thomas, DJ | 1 |
| Braithwaite, RA; Brown, SS; Church, HJ; Day, JP | 1 |
| Choudhuri, S; Klaassen, CD; Kramer, KK; Liu, J | 1 |
| Kawada, T; Suzuki, S; Tohyama, C | 1 |
| de Haan, FA; Marinussen, MP; van der Zee, SE | 1 |
| Galdzicki, Z; Hanbauer, I; Rapoport, SI; Scortegagna, M | 1 |
| Brand, IA; Kleineke, JW | 1 |
| Fujiwara, Y; Kaji, T; Sakamoto, M; Watanabe, S | 1 |
| Minami, T; Namikawa, K; Okazaki, Y | 1 |
| Bae, DS; Campain, JA; Carter, WH; Gennings, C; Yang, RS | 1 |
| Klaassen, CD; Liu, Y; Park, JD | 1 |
| Cherian, MG; Dawson, T; Diwan, BA; Goyer, RA; Horton, JL; Liu, J; Qu, W; Waalkes, MP | 1 |
| Hao, S; Li, X; Liu, Y; Ru, B | 1 |
| Hao, S; Ru, B; Tang, Q; Tian, P | 1 |
| Blasco, J; Campana, O; Sarasquete, C | 1 |
| Borgmann, U; Dixon, DG; Gillis, PL; Reynoldson, TB | 1 |
| Diwan, BA; Goyer, RA; Liu, J; Waalkes, MP | 1 |
| Curík, R; Holusa, R; Rencová, J; Veselá, G; Vlková, A | 1 |
| Brzóska, MM; Jurczuk, M; Moniuszko-Jakoniuk, J | 1 |
| Li, H; Ma, HY; Wang, JC; Xu, FS | 1 |
| Annis, ML; May, TW; Roberts, AP; Schmitt, CJ; Tillitt, DE; Whyte, JJ | 1 |
| Jamieson, JA; Stringer, DM; Taylor, CG; Zahradka, P | 1 |
| Jamieson, JA; Shuhyta, JN; Taylor, CG | 1 |
| Evje, L; Flaten, TP; Gellein, K; Nordberg, M; Roos, PM; Syversen, T; Vesterberg, O | 1 |
| Atli, G; Canli, M | 1 |
| Azlan, A; Ismail, A; Ismail, AR; Noorhaidah, A; Nor Azwady, AA; Siraj, SS; Tan, SG; Yap, CK | 1 |
| Dehn, PF; Moran, T; Shea, J | 1 |
| Bervoets, L; Blust, R; Dauwe, T; De Coen, W; Eens, M; Van Campenhout, K; Vanparys, C | 1 |
| Li, HC; Liu, KL; Ru, BG; Shen, L; Sheng, JP | 1 |
| Cooper, RN; Diwan, BA; Goyer, RA; Qu, W; Waalkes, MP; Zuo, P | 1 |
| Huang, GY; Wang, YS | 2 |
| Aleo, MF; Apostoli, P; Bettoni, F; Grigolato, PG; Lavazza, A; Morandini, F; Rezzani, R; Schena, I; Stacchiotti, A | 1 |
| Beier, JC; Githure, JI; Hassanali, A; Impoinvil, DE; Keating, J; Kenya, EU; Mbogo, CM; Mireji, PO; Muturi, MN; Nyambaka, H | 1 |
| Benitez, MA; Mendez-Armenta, M; Montes, S; Rembao, D; Rios, C; Sanin, LH | 1 |
| Chen, HI; Chen, YC; Chiu, YW; Chuang, HY; Hsu, YK; Li, WF | 1 |
| Blust, R; Bobbaers, R; De Boeck, G; Eyckmans, M; Lardon, I; Sinha, AK | 1 |
| Biagianti-Risbourg, S; Delahaut, L; Garric, J; Geffard, A; Geffard, O; Sartelet, H | 1 |
| Diwan, BA; Tokar, EJ; Waalkes, MP | 1 |
| Kibayashi, K; Koyama, H; Nakao, K; Taki, T | 1 |
| Dong, CJ; Liu, JY; Wang, Y; Yu, SS | 1 |
| Rui, Q; Wang, D; Wu, Q; Ye, B | 1 |
| Cavalcante, DG; Martinez, CB; Monteiro, V; Sofia, SH; Viléla, MB | 1 |
| Balamurugan, K; Pandian, SK; Vigneshkumar, B | 1 |
| Genzer, J; Hidasova, D; Srogl, J; Voltrova, S | 1 |
| Aliyev, V; Kayaaltı, Z; Söylemezoğlu, T | 1 |
| Almaguer-Cantú, V; Balderas-Rentería, I; Morales-Ramos, LH | 1 |
| Bizoń, A; Milnerowicz, H; Milnerowicz-Nabzdyk, E; Zalewska, M; Zimmer, M | 1 |
| Guo, Y; Huo, X; Li, W; Xu, X; Yi, D; Zhang, Q; Zhao, Z; Zhou, T; Zhu, M | 1 |
| Kayaaltı, Z; Söylemezoğlu, T; Tekin, D | 1 |
| Gao, J; He, R; Li, J; Lu, Y; Peng, B | 1 |
| Andrzejak, R; Antonowicz-Juchniewicz, J; Bizon, A; Milnerowicz, H | 1 |
| Atala, A | 1 |
| Dubey, SK; Naik, MM; Pandey, A | 1 |
| Choongo, K; Darwish, WS; Ikenaka, Y; Ishizuka, M; Konnai, S; Mainda, G; Muroya, T; Muzandu, K; Nakayama, SM; Teraoka, H; Umemura, T; Yabe, J | 1 |
| Salińska, A; Włostowski, T; Zambrzycka, E | 1 |
| Darwish, WS; Ikenaka, Y; Ishizuka, M | 1 |
| Filipović Marijić, V; Raspor, B; Vardić Smrzlić, I | 1 |
| Atagana, HI; Jingchun, L; Shijun, W; Wenlin, W; Yuhong, L | 1 |
| Arambourou, H; Beisel, JN; Branchu, P; Gismondi, E | 1 |
| Li, X; Liu, P; Liu, X; Lu, X; Wu, G; Zheng, L | 1 |
| Galitsopoulou, A; Georgantelis, D; Kontominas, MG | 1 |
| Dai, S; He, C; Jia, R; Li, L; Liang, X; Lu, H; Lv, C; Shu, Y; Song, X; Xu, J; Yin, Z; Yuan, G; Zhang, W | 1 |
| Ding, J; Liang, Y; Lu, G | 1 |
| Darabedian, N; He, Y; Liang, Y; Liu, M; Wu, D; Xiang, J; Zhou, F | 1 |
| Rodríguez-Sastre, MA; Rojas, E; Valverde, M | 1 |
| Cao, W; Wang, C; Wang, J; Zhang, F | 1 |
| Agrawal, S; Bhatnagar, P; Flora, G; Flora, SJ | 1 |
| Antunes, S; Cardoso, P; Figueira, E; Freitas, R; Martins, R; Moreira, A; Pires, A; Soares, AM; Velez, C | 1 |
| Cao, DJ; Deng, JW; Li, H; Liang, YG; Shi, XD; Xie, PP; Zhang, HM | 1 |
| Barrientos, EY; Díaz-Muñoz, M; Flores, A; Hernández-Plata, E; Martínez-Alfaro, M; Méndez, I; Quiroz-Compeán, F; Ramírez-Garcia, G; Robles, J; Rodríguez-Morales, NM; Wrobel, K | 1 |
| Han, S; Liu, J; Wang, S; Zhao, Y; Zhou, L | 1 |
| Brundo, MV; Copat, C; Ferrante, M; Giannetto, A; Longo, G; Maisano, M; Mauceri, A; Mazzei, V | 1 |
| Fillmann, G; Hauser-Davis, RA; Kehrig, HA; Seixas, TG | 1 |
| Bobak, Ł; Nowacki, D; Skoczyńska, A; Smyk, B; Szuba, A; Trziszka, T; Turczyn, B; Wojakowska, A | 1 |
| Bernard, F; Brulle, F; Cuny, D; Deram, A; Dumez, S; Lemière, S; Nesslany, F; Platel, A; Vandenbulcke, F | 1 |
| Antunes, LM; Barbosa, F; Barcelos, GR; Cólus, IM; Fernandes, KC; Martins, AC; Oliveira, AÁ | 1 |
| Austin, RN; Carpenter, MC; Croteau, ML; DeSilva, S; Gleaton, A; Goundie, B; Shami Shah, A; Stevenson, MJ; Su, A; Wilcox, DE | 1 |
| Balakrishnan, RM; Jacob, JM; Sharma, S | 1 |
| Bai, W; Huang, Y; Liu, D; Su, Z; Xiang, Q; Xiao, X; Zhang, C; Zhang, Q | 1 |
| Pirzadeh, S; Shahpiri, A | 1 |
| Antonowicz-Juchniewicz, J; Bizoń, A; Milnerowicz, H; Milnerowicz, M; Śliwińska-Mossoń, M | 1 |
| Martinez, CBDR; Nascimento, CRB; Risso, WE | 1 |
| Dubey, SK; Meena, RM; Shamim, K; Sharma, J | 1 |
| Amorim, FA; da Silva, EG; de Jesus, RM; Dias, F; Dos Santos, AM; Hauser-Davis, RA; Novaes, CG; Pacheco, CS; Saint'Pierre, TD | 1 |
| Durkalec, M; Dzięgiel, P; Grzegrzółka, J; Kolenda, R; Kołacz, R; Nawrocka, A; Owczarek, T; Posyniak, A; Schierack, P; Socha, P; Szkoda, J; Żmudzki, J | 1 |
| Kang, JC; Kim, JH | 1 |
| Cui, M; Hartley, W; Pan, W; Qin, Y; Shi, L; Wu, C; Wu, H; Xue, S | 1 |
| Kang, JC; Kim, JH; Oh, CW | 1 |
| Merrifield-MacRae, ME; Stillman, MJ; Wong, DL | 1 |
| Abd El-Hack, ME; Ahmed, SYA; Alagawany, M; El-Sayed, SAA; Farag, MR; Samak, DH | 1 |
| Aouini, F; Blasco, J; Elcafsi, M; Trombini, C; Volland, M | 1 |
| Duan, L; Kong, JJ; Sun, Y; Wang, TQ | 1 |
| Abessa, DMS; Bordon, IC; Campos, BG; Emerenciano, AK; Favaro, DIT; Gusso-Choueri, PK; Melo, JRC; Silva, JRMCD | 1 |
| Austin, RN; Capdevila, M; Leiva-Presa, À; Palacios, Ò; Pérez-Zúñiga, C | 1 |
| Blagojević, DP; Ćelić, AS; Kojić, D; Nikolić, TV; Petri, ET; Plavša, JJ; Purać, J | 1 |
| Gan, HT; Liu, TH; Meng, X; Xu, GC; Xu, JT; Xu, XH; Yao, HY; Zhu, XY | 1 |
| Guo, Y; Han, J; Hu, S; Li, S; Wu, H; Yang, L; Zhou, B | 2 |
| Ali, N; Chen, Q; Liu, X; Wang, M; Wang, Z; Zhang, J | 1 |
| Dubey, M; Firdaus, H; Kumari, C; Nanda, KP | 1 |
| Das, S; Kumari, S | 1 |
| Bhattacharya, S; Chaudhuri, P; Das, S; Gachhui, R; Ghosh, S; Mukherjee, A; Mukherjee, J; Parvin, R; Roy, U; Roychowdhury, T; Sarkar, S | 1 |
| Kawasaki, S; Mwandira, W; Nakashima, K; Sato, T; Togo, Y | 1 |
| Abessa, DMS; Blasco, J; Catharino, MGM; Duarte, LFA; Moreira, EG; Moreno, BB; Nobre, CR; Pereira, CDS; Trombini, C | 1 |
| Chuang, HY; Dai, CY; Lee, SS; Lin, CI; Wang, CL; Yang, CC | 1 |
| Goyal, T; Kumar, PVK; Mitra, P; Sharma, P; Sharma, S; Singh, P | 1 |
| C, K; Rajkumar, J; S, PP | 1 |
| Aziz, N; Butt, A | 1 |
| Adams, DH; Hauser-Davis, RA; Rocha, RCC; Saint'Pierre, TD | 1 |
| Emtiazi, G; Etemadzadeh, SS | 1 |
| Dong, Y; Li, S; Shi, K; Wang, G; Xia, X; Zhou, Z; Zhu, L | 1 |
| Antit, M; Cafsi, ME; Chouba, L; Hajji, T; Kheriji, S; Mhadhbi, L; Rabeh, I; Telahigue, K | 1 |
| Bhardwaj, A; Kumar, VL; Sharma, S | 1 |
| Li, Y; Moussian, B; Qiao, H; Tian, X; Wang, Y; Yang, S; Yu, X; Zang, X; Zhu, C | 1 |
4 review(s) available for lead and metallothionein
| Article | Year |
|---|---|
[Cellular and molecular biological aspects in environmental toxicology].
Topics: Cadmium; Carcinogens, Environmental; Environmental Pollutants; Environmental Pollution; Humans; Immunity; Kidney; Lead; Lung; Metallothionein; Nervous System | 1986 |
Biological and health implications of toxic heavy metal and essential trace element interactions.
Topics: Animals; Bone and Bones; Cadmium; Calcium; Copper; Diet; Drug Interactions; Environmental Exposure; Humans; Iron; Lead; Lung; Manganese; Mercury; Metallothionein; Metals; Selenium; Smoking; Tissue Distribution; Trace Elements; Zinc | 1987 |
[Studies of metals and metallothionein in tissue].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Calcium; Cisplatin; Diabetes Mellitus; Humans; Lead; Metallothionein; Pancreas; Rats; Renal Dialysis; Trace Elements; Zinc | 2000 |
Lead(II) Binding in Metallothioneins.
Topics: Animals; Humans; Lead; Lead Poisoning; Metallothionein; Protein Binding | 2017 |
139 other study(ies) available for lead and metallothionein
| Article | Year |
|---|---|
Effect of metallothionein on hepatic disposition of metals.
Topics: Animals; Arsenic; Cadmium; Copper; Injections, Subcutaneous; Lead; Liver; Male; Manganese; Mercury; Metalloproteins; Metallothionein; Methylmercury Compounds; Rats; Silver; Zinc | 1978 |
Hepatic and renal metallothionein concentrations in cows, swine, and chickens given cadmium and lead in feed.
Topics: Animals; Cadmium; Cattle; Chickens; Female; Kidney; Lead; Liver; Male; Metalloproteins; Metallothionein | 1978 |
Isolation of a factor that protects against lead inhibition of hepatic and erythrocytic uroporphyrinogen I synthetase activity.
Topics: Ammonia-Lyases; Animals; Cytoplasm; Dialysis; Erythrocytes; Hydroxymethylbilane Synthase; Kinetics; Lead; Liver; Male; Metallothionein; Proteins; Rats | 1976 |
Effect of metals on interleukin-6 (IL-6) mitogenic stimulation of murine hybridoma cells.
Topics: Animals; B-Lymphocytes; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Growth Inhibitors; Hybridomas; Interleukin-6; Lead; Lymphocyte Activation; Metallothionein; Metals; Mice | 1992 |
Choroid plexus protects cerebrospinal fluid against toxic metals.
Topics: Animals; Arsenic; Blood Chemical Analysis; Cadmium; Cerebral Cortex; Cerebrospinal Fluid; Choroid Plexus; Cysteine; Dose-Response Relationship, Drug; Glutathione; Lead; Mercury; Metallothionein; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds | 1991 |
The protective effect of metallothionein on the toxicity of various metals in rat primary hepatocyte culture.
Topics: Animals; Cells, Cultured; Copper; L-Lactate Dehydrogenase; Lead; Liver; Male; Mercury; Metallothionein; Metals; Potassium; Rats; Rats, Inbred Strains; Silver; Zinc | 1991 |
Combined nephrotoxicity of methylmercury, lead, and cadmium in Pekin ducks: metallothionein, metal interactions, and histopathology.
Topics: Animals; Cadmium; Diet; Drug Interactions; Ducks; Female; Kidney Cortex; Kidney Diseases; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Lead; Metallothionein; Methylmercury Compounds; Tissue Distribution; Trace Elements | 1989 |
EXAFS studies of metallothionein.
Topics: Animals; Binding Sites; Cadmium; Copper; Lead; Liver; Mercury; Metallothionein; Rabbits; Sheep; Silver; Spectrum Analysis; Sulfur; Swine; X-Rays; Zinc | 1987 |
Regulatory roles of high-affinity metal-binding proteins in mediating lead effects on delta-aminolevulinic acid dehydratase.
Topics: Animals; Brain; Carrier Proteins; Cattle; Copper; Kidney; Lead; Liver; Metallothionein; Porphobilinogen Synthase; Rats; Zinc | 1987 |
An immunological study of a Pb-thionein like protein in rat liver.
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Electrophoresis, Polyacrylamide Gel; Immunologic Techniques; Lead; Liver; Male; Metallothionein; Organometallic Compounds; Rats; Rats, Inbred Strains; Zinc | 1986 |
Metal constitution of metallothionein influences inhibition of delta-aminolaevulinic acid dehydratase (porphobilinogen synthase) by lead.
Topics: Animals; Cadmium; Chromatography, Gel; Kidney; Lead; Liver; Male; Metallothionein; Porphobilinogen Synthase; Rats; Zinc | 1987 |
Chemical form of cadmium (and other heavy metals) in rice and wheat plants.
Topics: Cadmium; Copper; Lead; Metallothionein; Molecular Weight; Nickel; Oryza; Plant Proteins; Spectrophotometry, Ultraviolet; Triticum | 1986 |
The proteinuria of industrial lead intoxication.
Topics: Adult; Cadmium; Humans; Kidney; Lead; Lead Poisoning; Male; Metallothionein; Molecular Weight; Proteinuria | 1986 |
Kidney zinc-thionein regulation of delta-aminolevulinic acid dehydratase inhibition by lead.
Topics: Animals; Apoproteins; Cattle; Kidney; Lead; Liver; Male; Metallothionein; Porphobilinogen Synthase; Rats; Zinc | 1987 |
Simultaneous induction of Pb-metallothionein-like protein and Zn-thionein in the liver of rats given lead acetate.
Topics: Amino Acids; Animals; Chromatography, Gel; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Lead; Liver; Macromolecular Substances; Male; Metallothionein; Organometallic Compounds; Rats; Rats, Inbred Strains | 1986 |
Induction of metallothionein after lead administration by three injection routes in mice.
Topics: Animals; Calcium; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Kidney; Lead; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Organometallic Compounds; Spleen; Zinc | 1986 |
Mechanism of renal lead-binding protein reversal of delta-aminolevulinic acid dehydratase inhibition by lead.
Topics: Animals; Carrier Proteins; Kidney; Lead; Liver; Male; Metallothionein; Molecular Weight; Porphobilinogen Synthase; Rats; Zinc | 1985 |
Purification and characterization of lead-induced zinc thionein in the liver of rats.
Topics: Amino Acids; Animals; Lead; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains | 1985 |
Rat kidney epithelial cell culture for metal toxicity studies.
Topics: Animals; Cadmium; Cell Survival; Cells, Cultured; Culture Media; Diffusion; Epithelium; Kidney Diseases; Kidney Tubules, Proximal; Lead; Mercury; Metallothionein; Metals; Rats; Zinc | 1985 |
Reversal of heavy metal-directed inhibition of RNA synthesis in isolated mouse liver nuclei.
Topics: Animals; Apoproteins; Cadmium; Cadmium Chloride; Cell Nucleus; Chlorides; Copper; Lead; Liver; Male; Metallothionein; Metals; Mice; RNA; Zinc; Zinc Compounds | 1981 |
Intracellular sites of toxic metals.
Topics: Cadmium; Cell Nucleus; Chelating Agents; Gold; Humans; Inclusion Bodies; Lead; Lead Poisoning; Metallothionein; Metals; Methylmercury Compounds; Subcellular Fractions | 1983 |
In vitro effects of lead, mercury and cadmium on the enzymic activity of red-blood cell pyrimidine 5'-nucleotidase.
Topics: 5'-Nucleotidase; Cadmium; Erythrocytes; Humans; Lead; Mercury; Metallothionein; Nucleotidases; Spectrophotometry, Atomic | 1984 |
Chain length-dependent Pb(II)-coordination in phytochelatins.
Topics: Animals; Cations, Divalent; Circular Dichroism; Glutathione; Lead; Liver; Metalloproteins; Metallothionein; Phytochelatins; Plant Proteins; Protein Binding; Protein Conformation; Rats; Spectrophotometry | 1995 |
Severe damage of cultured vascular endothelial cell monolayer after simultaneous exposure to cadmium and lead.
Topics: Animals; Aorta; Cadmium; Cattle; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Lead; Metallothionein | 1995 |
Influence of dietary iron deficiency on nickel, lead and cadmium intoxication.
Topics: Animals; Cadmium; Iron; Iron Deficiencies; Lead; Male; Metallothionein; Nickel; Rats | 1994 |
Influence of dietary iron deficiency on acute metal intoxication.
Topics: Animals; Cadmium; Cadmium Poisoning; Diet; Intestinal Mucosa; Intestines; Iron Deficiencies; Kidney; Lead; Lead Poisoning; Liver; Male; Metallothionein; Nickel; Rats; Rats, Inbred Strains; Trace Elements | 1993 |
Osteotoxicity of cadmium and lead in HOS TE 85 and ROS 17/2.8 cells: relation to metallothionein induction and mitochondrial binding.
Topics: Animals; Bone and Bones; Cadmium; Cell Division; Humans; Lead; Metallothionein; Mitochondria; Osteosarcoma; Rats; Subcellular Fractions; Tumor Cells, Cultured | 1993 |
Binding of lead to a metallothionein-like protein in human erythrocytes.
Topics: Adult; Carrier Proteins; Erythrocytes; Humans; In Vitro Techniques; Isoelectric Point; Lead; Lead Poisoning; Male; Metallothionein; Molecular Weight; Occupational Diseases; Occupational Exposure; Protein Binding | 1993 |
Induction of metallothionein mRNA and protein in murine astrocyte cultures.
Topics: Animals; Astrocytes; Blotting, Northern; Brain; Cadmium; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Glucocorticoids; Immunohistochemistry; Lead; Liver; Mercury; Metallothionein; Methylmercury Compounds; Mice; Nucleic Acid Hybridization; RNA, Messenger; Zinc | 1996 |
Effects of cadmium and lead exposure on urinary N-acetyl-beta-D-glucosaminidase, beta 2-microglobulin and metallothionein of workers.
Topics: Acetylglucosaminidase; Adult; beta 2-Microglobulin; Cadmium; Environmental Monitoring; Humans; Lead; Male; Metallothionein; Middle Aged; Occupational Exposure; Pigments, Biological; Predictive Value of Tests; Reproducibility of Results; Resins, Plant | 1995 |
Effect of Cd or Pb addition to Cu-contaminated soil on tissue Cu accumulation in the earthworm, Dendrobaena veneta.
Topics: Animals; Biological Availability; Cadmium; Copper; Lead; Metallothionein; Oligochaeta; Soil Pollutants | 1997 |
In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation.
Topics: Acetylcysteine; Animals; Astrocytes; Blotting, Western; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Free Radical Scavengers; Hydrogen Peroxide; Lead; Male; Metallothionein; Mice; Mice, Inbred C57BL; Oxidants; Oxidation-Reduction; Receptors, Glutamate; Stimulation, Chemical; Trisomy; Up-Regulation | 1998 |
Rapid changes in intracellular Zn2+ in rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Cadmium; Chlorides; Copper; Dose-Response Relationship, Drug; Fluorescent Dyes; Hemostatics; Lead; Liver; Mercury; Metallothionein; Nickel; Quinolones; Rats; Tosyl Compounds; Zinc; Zinc Compounds | 1997 |
Repair of wounded monolayers of cultured vascular endothelial cells after simultaneous exposure to lead and zinc.
Topics: Animals; Astringents; Calcium; Cattle; Cell Division; Cells, Cultured; DNA; Drug Interactions; Endothelium, Vascular; Homeostasis; L-Lactate Dehydrogenase; Lead; Metallothionein; Mitogens; Muscle, Smooth, Vascular; Nitrates; Zinc Sulfate | 1998 |
Toxicological interactions among arsenic, cadmium, chromium, and lead in human keratinocytes.
Topics: Arsenic; Cadmium; Cell Line, Transformed; Cell Survival; Chromium; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Humans; Keratinocytes; Lead; Metallothionein; Metals, Heavy | 2001 |
Protective effect of metallothionein against the toxicity of cadmium and other metals(1).
Topics: Animals; Arsenic; Cadmium; Cadmium Chloride; Copper; Dose-Response Relationship, Drug; Iron; Lead; Lethal Dose 50; Mercury; Metallothionein; Metals; Mice; Mice, Knockout; Zinc | 2001 |
The metallothionein-null phenotype is associated with heightened sensitivity to lead toxicity and an inability to form inclusion bodies.
Topics: Animals; Cells, Cultured; Genetic Predisposition to Disease; Inclusion Bodies; Kidney; Lead; Lead Poisoning; Male; Metallothionein; Mice; Mice, Knockout | 2002 |
[Study on the form and stability of alpha and beta domain of metallothionein binding to lead (II)].
Topics: Drug Interactions; Lead; Metallothionein; Spectrophotometry, Ultraviolet | 2001 |
[Protective effect of extra metallothioneins from rabbit liver induced by zinc on toxicity of lead in rat primary hepatocyte culture].
Topics: Animals; Cells, Cultured; Hepatocytes; Lead; Male; Metallothionein; Rabbits; Rats; Rats, Wistar; Zinc | 2002 |
Effect of lead on ALA-D activity, metallothionein levels, and lipid peroxidation in blood, kidney, and liver of the toadfish Halobatrachus didactylus.
Topics: Animals; Environmental Exposure; Fishes; Kidney; Lead; Lipid Peroxidation; Liver; Metallothionein; Porphobilinogen Synthase; Tissue Distribution | 2003 |
Uptake and depuration of cadmium, nickel, and lead in laboratory-exposed Tubifex tubifex and corresponding changes in the concentration of a metallothionein-like protein.
Topics: Animals; Cadmium; Digestive System; Lead; Metallothionein; Nickel; Oligochaeta; Reproducibility of Results; Tissue Distribution | 2004 |
Metallothionein-I/II double knockout mice are hypersensitive to lead-induced kidney carcinogenesis: role of inclusion body formation.
Topics: Animals; Body Weight; Inclusion Bodies; Kidney; Kidney Neoplasms; Lead; Metallothionein; Mice; Mice, Knockout | 2004 |
Influence of heavy metals upon the retention and mobilization of polonium-210 in rats.
Topics: Animals; Binding Sites; Cadmium; Cations; Chelating Agents; Erythrocytes; Feces; Female; Immunohistochemistry; Lead; Metallothionein; Metals, Heavy; Methylmercury Compounds; Polonium; Radioisotopes; Rats; Rats, Wistar; Time Factors; Tissue Distribution | 2004 |
Involvement of some low-molecular thiols in the peroxidative mechanisms of lead and ethanol action on rat liver and kidney.
Topics: Aminolevulinic Acid; Animals; Central Nervous System Depressants; Ethanol; Glutathione; Kidney; Lead; Lipid Peroxidation; Liver; Male; Metallothionein; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Sulfhydryl Compounds | 2006 |
[Expression and significance of metallothionein in the placenta of women with low level lead exposure during pregnancy].
Topics: Adult; Decidua; Endothelial Cells; Female; Fetal Blood; Humans; Immunohistochemistry; Lead; Maternal Exposure; Maternal-Fetal Exchange; Metallothionein; Placenta; Pregnancy; Pregnancy Trimester, Second; Trophoblasts | 2006 |
Biomarkers of metals exposure in fish from lead-zinc mining areas of southeastern Missouri, USA.
Topics: Animals; Biomarkers; Cadmium; Cyprinidae; Environmental Exposure; Environmental Monitoring; Fishes; Fresh Water; Hemoglobins; Iron; Lead; Lipid Peroxidation; Lipid Peroxides; Liver; Metallothionein; Mining; Missouri; Perciformes; Porphobilinogen Synthase; Protoporphyrins; RNA, Messenger; Water Pollutants, Chemical; Zinc | 2007 |
Dietary zinc attenuates renal lead deposition but metallothionein is not directly involved.
Topics: Animals; Blotting, Western; Dietary Supplements; Immunohistochemistry; Kidney; Lead; Male; Metallothionein; Rats; Rats, Sprague-Dawley; Tissue Distribution; Weaning; Zinc | 2008 |
Lead does not affect transcription of intestinal zinc-binding proteins in growing rats.
Topics: Animals; Cation Transport Proteins; Intestine, Small; Iron; Lead; Liver; Male; Metallothionein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trace Elements; Transcription, Genetic; Zinc | 2007 |
Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS.
Topics: Adult; Cadmium; Calibration; Chromatography, High Pressure Liquid; Copper; Female; Humans; Iron; Lead; Male; Manganese; Metallothionein; Middle Aged; Molecular Weight; Particle Size; Quality Control; Reproducibility of Results; Trace Elements; Zinc | 2007 |
Natural occurrence of metallothioneinlike proteins in liver tissues of four fish species from the northeast Mediterranean Sea.
Topics: Animals; Cadmium; Chromatography, Gel; Environmental Monitoring; Fishes; Germany; Lead; Liver; Mediterranean Sea; Metallothionein; Metals; Perciformes; Smegmamorpha; Sulfhydryl Compounds; Water Pollutants, Chemical | 2007 |
Telescopium telescopium as potential biomonitors of Cu, Zn, and Pb for the tropical intertidal area.
Topics: Animals; Copper; Environmental Monitoring; Gastropoda; Industrial Waste; Lead; Malaysia; Metallothionein; Seawater; Soil Pollutants; Tissue Distribution; Water Pollutants, Chemical; Zinc | 2009 |
A bioassay for metals utilizing a human cell line.
Topics: Biological Assay; Cadmium; Carcinoma, Hepatocellular; Cell Line, Tumor; Environmental Monitoring; Fresh Water; Geologic Sediments; Humans; Lead; Liver Neoplasms; Mercury; Metallothionein; Metals, Heavy; Spectrophotometry, Atomic; Water Pollutants, Chemical | 2008 |
Metallothioneins (MTs) and delta-aminolevulinic acid dehydratase (ALAd) as biomarkers of metal pollution in great tits (Parus major) along a pollution gradient.
Topics: Animals; Biomarkers; Birds; Cadmium; Dose-Response Relationship, Drug; Environmental Monitoring; Environmental Pollutants; Geography; Kidney; Lead; Liver; Metallothionein; Metals, Heavy; Porphobilinogen Synthase; Tissue Distribution; Zinc | 2008 |
[Distribution of Pb and Zn in transgenic metallothionein tobacco].
Topics: Lead; Metallothionein; Nicotiana; Plant Leaves; Plant Roots; Plant Stems; Plants, Genetically Modified; Zinc | 2008 |
Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation.
Topics: alpha-Synuclein; Animals; Blotting, Western; Cells, Cultured; DNA; Immunohistochemistry; Inclusion Bodies; Lead; Metallothionein; Mice; Mice, Knockout; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Transfection | 2009 |
Expression analysis of type 2 metallothionein gene in mangrove species (Bruguiera gymnorrhiza) under heavy metal stress.
Topics: Copper; Lead; Metallothionein; Metals, Heavy; Rhizophoraceae; RNA, Ribosomal, 18S; Zinc | 2009 |
Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead.
Topics: Animals; Apoptosis; Biomarkers; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Glutathione; Glutathione Transferase; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Kidney Tubules, Proximal; Lead; Mercuric Chloride; Metallothionein; Mitochondria; Molecular Chaperones; Necrosis; Nitric Oxide; Oxidative Stress; Rats; Reactive Oxygen Species; Time Factors | 2009 |
Expression of metallothionein and alpha-tubulin in heavy metal-tolerant Anopheles gambiae sensu stricto (Diptera: Culicidae).
Topics: Animals; Anopheles; Cadmium; Copper; Drug Tolerance; Lead; Lethal Dose 50; Metallothionein; Metals, Heavy; RNA, Messenger; Tubulin | 2010 |
Mother-fetus transference of lead and cadmium in rats: involvement of metallothionein.
Topics: Administration, Oral; Animals; Birth Weight; Blood; Brain; Cadmium; Calibration; Cattle; Dose-Response Relationship, Drug; Female; Fetus; Immunohistochemistry; Lead; Maternal-Fetal Exchange; Metallothionein; Placenta; Pregnancy; Quality Control; Rats; Reference Standards; Spectrophotometry, Atomic | 2009 |
The association of metallothionein-4 gene polymorphism and renal function in long-term lead-exposed workers.
Topics: Adult; Alleles; Cross-Sectional Studies; Genotype; Humans; Kidney; Kidney Function Tests; Lead; Metallothionein; Middle Aged; Occupational Exposure; Polymorphism, Genetic | 2010 |
Metal accumulation and metallothionein induction in the spotted dogfish Scyliorhinus canicula.
Topics: Animals; Body Burden; Cadmium Compounds; Copper; Dogfish; Fish Proteins; Lead; Metallothionein; Metals; Nickel; Nitrates; Silver Nitrate; Time Factors; Tissue Distribution; Up-Regulation; Water Pollutants, Chemical; Water-Electrolyte Balance | 2010 |
Subcellular compartmentalization of cadmium, nickel, and lead in Gammarus fossarum: Comparison of methods.
Topics: Amphipoda; Animals; Cadmium; Chemical Fractionation; Chromatography, Gel; Cytosol; Lead; Metallothionein; Nickel | 2010 |
Expression and characterization analysis of type 2 metallothionein from grey mangrove species (Avicennia marina) in response to metal stress.
Topics: Avicennia; Base Sequence; Cadmium; Copper; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione Transferase; Homeostasis; Lead; Metallothionein; Metals; Polymerase Chain Reaction; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Water Pollutants, Chemical; Zinc | 2010 |
Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice.
Topics: Animals; Carcinogens, Environmental; Dose-Response Relationship, Drug; Female; Hyperplasia; Kidney Diseases, Cystic; Lead; Male; Maternal Exposure; Metallothionein; Mice; Mice, Knockout; Precancerous Conditions; Pregnancy; Prenatal Exposure Delayed Effects; Teratoma; Testicular Neoplasms; Urinary Bladder Diseases | 2010 |
Changes in the brain after intracerebral implantation of a lead pellet in the rat.
Topics: Animals; Apoptosis; Brain; Brain Chemistry; Cell Count; Immunohistochemistry; Lead; Lead Poisoning; Macrophages; Male; Metallothionein; Nerve Degeneration; Neurons; Neutrophils; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Characterization of a novel rice metallothionein gene promoter: its tissue specificity and heavy metal responsiveness.
Topics: Aluminum; Cadmium; Cobalt; Copper; Lead; Metallothionein; Metals, Heavy; Oryza; Plant Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Zinc | 2010 |
Metallothioneins are required for formation of cross-adaptation response to neurobehavioral toxicity from lead and mercury exposure in nematodes.
Topics: Adaptation, Physiological; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Gene Expression Regulation; Genetic Complementation Test; Green Fluorescent Proteins; Heat-Shock Response; Hot Temperature; Lead; Mercuric Chloride; Mercury; Metallothionein; Motor Activity; Mutation; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
In vivo and in vitro exposures for the evaluation of the genotoxic effects of lead on the Neotropical freshwater fish Prochilodus lineatus.
Topics: Animals; Cell Survival; Comet Assay; Environmental Monitoring; Erythrocytes; Fishes; Fresh Water; Gills; Lead; Liver; Lysosomes; Metallothionein; Mutagens; Water Pollutants, Chemical | 2011 |
Catalase activity and innate immune response of Caenorhabditis elegans against the heavy metal toxin lead.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catalase; Gene Expression; Green Fluorescent Proteins; Immunity, Innate; Lead; Lead Poisoning; Metallothionein; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa; Real-Time Polymerase Chain Reaction; Up-Regulation | 2013 |
Metallothionein-inspired prototype of molecular pincer.
Topics: Amides; Cysteine; Imides; Lead; Metallothionein; Oxidation-Reduction; Zinc | 2011 |
The potential effect of metallothionein 2A -5A/G single nucleotide polymorphism on blood cadmium, lead, zinc and copper levels.
Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Cadmium; Copper; Female; Genetic Markers; Genotype; Guanine Nucleotides; Heavy Metal Poisoning; Humans; Lead; Male; Metallothionein; Metals, Heavy; Middle Aged; Poisoning; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Young Adult; Zinc | 2011 |
Biosorption of lead (II) and cadmium (II) using Escherichia coli genetically engineered with mice metallothionein I.
Topics: Animals; Cadmium; Escherichia coli; Genetic Engineering; Lead; Metallothionein; Mice; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2011 |
Changes in pro/antioxidant balance in smoking and non-smoking pregnant women with intrauterine growth restriction.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Antioxidants; Cadmium; Copper; Cotinine; Deoxyguanosine; Environmental Pollutants; Female; Fetal Blood; Fetal Growth Retardation; Glutathione; Glutathione Peroxidase; Humans; Lead; Malondialdehyde; Metallothionein; Pregnancy; Smoking; Superoxide Dismutase; Young Adult; Zinc | 2011 |
Downregulation of placental S100P is associated with cadmium exposure in Guiyu, an e-waste recycling town in China.
Topics: Adult; Blotting, Western; Cadmium; Calcium-Binding Proteins; China; Down-Regulation; Electronic Waste; Environmental Exposure; Environmental Pollutants; Female; Humans; Lead; Male; Metallothionein; Neoplasm Proteins; Placenta; Polymerase Chain Reaction; Pregnancy; Recycling; RNA, Messenger; Spectrophotometry, Atomic; Young Adult | 2011 |
The effects of metallothionein 2A polymorphism on lead metabolism: are pregnant women with a heterozygote genotype for metallothionein 2A polymorphism and their newborns at risk of having higher blood lead levels?
Topics: Adolescent; Adult; Female; Fetal Blood; Heterozygote; Humans; Infant, Newborn; Lead; Metallothionein; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Risk Assessment; Turkey; Young Adult | 2012 |
[Attenuation effects of compatible medicines on arsenical and lead toxicity of badu shengji san].
Topics: Animals; Arsenic; Body Weight; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Kidney; Lead; Male; Malondialdehyde; Metallothionein; Rats; Rats, Sprague-Dawley; Skin; Superoxide Dismutase | 2011 |
The influence of the intensity of smoking and years of work in the metallurgy on pro-oxidant/antioxidant balance in the blood of smelters.
Topics: Adult; Arsenicals; Cadmium Compounds; Erythrocytes; Glutathione; Humans; Lead; Male; Malondialdehyde; Metallothionein; Metallurgy; Metals, Heavy; Middle Aged; Nicotiana; Occupational Exposure; Oxidative Stress; Oxidoreductases; Smoke; Smoking | 2013 |
Re.: Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice.
Topics: Animals; Carcinogens, Environmental; Female; Lead; Male; Maternal Exposure; Metallothionein; Pregnancy | 2011 |
Pseudomonas aeruginosa strain WI-1 from Mandovi estuary possesses metallothionein to alleviate lead toxicity and promotes plant growth.
Topics: Antibiosis; Biodegradation, Environmental; Electrophoresis, Polyacrylamide Gel; Fusarium; India; Lead; Metallothionein; Plant Development; Plants; Pseudomonas aeruginosa; Soil Microbiology; Soil Pollutants | 2012 |
Effects of environmental lead contamination on cattle in a lead/zinc mining area: changes in cattle immune systems on exposure to lead in vivo and in vitro.
Topics: Animals; Cattle; Cells, Cultured; Female; Heme Oxygenase-1; Interferon-gamma; Interleukin-1beta; Interleukin-6; Lead; Leukocytes, Mononuclear; Metallothionein; Mining; Nitric Oxide Synthase Type II; Organometallic Compounds; Soil Pollutants; Tumor Necrosis Factor-alpha; Zambia; Zinc | 2012 |
Effect of dietary cadmium and/or lead on histopathological changes in the kidneys and liver of bank voles Myodes glareolus kept in different group densities.
Topics: Animals; Arvicolinae; Cadmium; Female; Glutathione; Kidney; Lead; Lipid Peroxidation; Liver; Metallothionein; Poland; Population Density; Random Allocation; Spectrophotometry, Atomic; Trace Elements | 2012 |
Biological responses of xenobiotic metabolizing enzymes to lead exposure in cultured H4IIE rat cells.
Topics: Animals; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Lead; Metallothionein; Rats; RNA, Messenger | 2013 |
Effect of acanthocephalan infection on metal, total protein and metallothionein concentrations in European chub from a Sava River section with low metal contamination.
Topics: Acanthocephala; Animals; Cadmium; Carps; Copper; Croatia; Fish Diseases; Gastrointestinal Tract; Helminthiasis, Animal; Humans; Iron; Lead; Manganese; Metallothionein; Metals; Rivers; Silver; Water Pollutants, Chemical; Zinc | 2013 |
cDNA sequence encoding metallothionein protein from Aegiceras corniculatum and its gene expression induced by Pb²⁺ and Cd²⁺ stresses.
Topics: Amino Acid Sequence; Base Sequence; Cadmium; China; DNA, Complementary; Environmental Monitoring; Gene Expression; Lead; Metallothionein; Metals, Heavy; Molecular Sequence Data; Primulaceae; Wetlands | 2013 |
Biochemical and morphological responses in Chironomus riparius (Diptera, Chironomidae) larvae exposed to lead-spiked sediment.
Topics: Animals; Biomarkers; Chironomidae; Copper; Geologic Sediments; Larva; Lead; Malondialdehyde; Metallothionein; Water Pollutants, Chemical; Zinc | 2013 |
Simultaneous detection of multiple DNA targets based on encoding metal ions.
Topics: Biosensing Techniques; Cadmium; DNA; Electrochemical Techniques; Immunoassay; Ions; Lead; Limit of Detection; Metallothionein; Nucleic Acid Hybridization; Zinc | 2014 |
Effect of thermal processing and canning on cadmium and lead levels in California market squid: the role of metallothioneins.
Topics: Animals; Cadmium; California; Decapodiformes; Food Handling; Food, Preserved; Hot Temperature; Lead; Metallothionein; Seafood; Spectrophotometry, Atomic | 2013 |
Quantification of metallothionein on the liver and kidney of rats by subchronic lead and cadmium in combination.
Topics: Animals; Antioxidants; Cadmium; Female; Gene Expression; Immunohistochemistry; Indicators and Reagents; Kidney; Kidney Cortex; Lead; Liver; Male; Metallothionein; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2013 |
Evaluation of the interactive effects of lead, zinc and benzo(k)fluoranthene on crucian carp, Carassius carassius, using a multiple biomarker approach.
Topics: Animals; Biomarkers; Carps; Cytochrome P-450 CYP1A1; Fluorenes; Lead; Malondialdehyde; Metallothionein; Superoxide Dismutase; Water Pollutants, Chemical; Zinc | 2014 |
pH-dependent coordination of Pb2+ to metallothionein2: structures and insight into lead detoxification.
Topics: Animals; Circular Dichroism; Hydrogen-Ion Concentration; Inactivation, Metabolic; Lead; Magnetic Resonance Spectroscopy; Metallothionein; Protein Conformation; Proteolysis; Rabbits; Spectrophotometry, Ultraviolet | 2014 |
Assessing the impact of As-Cd-Pb metal mixture on cell transformation by two-stage Balb/c 3T3 cell assay.
Topics: 3T3 Cells; Animals; Arsenic; Biological Assay; Cadmium; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Cellular Senescence; DNA Damage; Humans; Lead; Metallothionein; Metals, Heavy; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Reactive Oxygen Species | 2014 |
The identification of metallothionein in rare minnow (Gobiocypris rarus) and its expression following heavy metal exposure.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cadmium; Copper; Cyprinidae; DNA, Complementary; Female; Fish Proteins; Gene Expression Regulation; Lead; Male; Metallothionein; Molecular Sequence Data; Sequence Analysis, DNA; Water Pollutants, Chemical | 2014 |
Comparative oxidative stress, metallothionein induction and organ toxicity following chronic exposure to arsenic, lead and mercury in rats.
Topics: Animals; Arsenic; Catalase; Glutathione; Glutathione Peroxidase; Kidney; Lead; Liver; Male; Mercury; Metallothionein; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2014 |
Venerupis decussata under environmentally relevant lead concentrations: Bioconcentration, tolerance, and biochemical alterations.
Topics: Animals; Biotransformation; Bivalvia; Catalase; Geologic Sediments; Glutathione Transferase; Lead; Mass Spectrometry; Metallothionein; Water Pollutants, Chemical | 2014 |
Effects of lead on tolerance, bioaccumulation, and antioxidative defense system of green algae, Cladophora.
Topics: Antioxidants; Biodegradation, Environmental; Chlorophyta; Drug Tolerance; Lead; Metallothionein; Water Pollutants, Chemical | 2015 |
Melatonin reduces lead levels in blood, brain and bone and increases lead excretion in rats subjected to subacute lead treatment.
Topics: Animals; Bone and Bones; Brain; Free Radical Scavengers; Kidney; Lead; Liver; Male; Melatonin; Metallothionein; Rats; Rats, Wistar; Tissue Distribution | 2015 |
Lead in the soil-mulberry (Morus alba L.)-silkworm (Bombyx mori) food chain: translocation and detoxification.
Topics: Animals; Bombyx; Dose-Response Relationship, Drug; Environmental Pollutants; Environmental Restoration and Remediation; Food Chain; Fruit; Inactivation, Metabolic; Lead; Metallothionein; Morus; Plant Leaves; Soil | 2015 |
Metallothioneins and heat shock proteins 70 in Armadillidium vulgare (Isopoda, Oniscidea) exposed to cadmium and lead.
Topics: Animals; Blotting, Western; Cadmium; Environmental Pollutants; Female; Hepatopancreas; HSP70 Heat-Shock Proteins; Immunohistochemistry; Isopoda; Lead; Male; Metallothionein | 2015 |
Trace-elements, methylmercury and metallothionein levels in Magellanic penguin (Spheniscus magellanicus) found stranded on the Southern Brazilian coast.
Topics: Animals; Atlantic Ocean; Biomarkers; Brazil; Cadmium; Environmental Monitoring; Feathers; Female; Inactivation, Metabolic; Kidney; Lead; Liver; Male; Mercury; Metallothionein; Methylmercury Compounds; Selenium; Spheniscidae; Trace Elements | 2015 |
Unsaturated fatty acids supplementation reduces blood lead level in rats.
Topics: Animals; Carrier Proteins; Dietary Fats, Unsaturated; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; In Vitro Techniques; Lead; Lead Poisoning; Lecithins; Linseed Oil; Lipids; Male; Mesenteric Arteries; Metallothionein; Norepinephrine; Olive Oil; Rats; Rats, Wistar; Vasoconstrictor Agents | 2015 |
Antioxidant defense gene analysis in Brassica oleracea and Trifolium repens exposed to Cd and/or Pb.
Topics: Antioxidants; Brassica; Cadmium; Environmental Monitoring; France; Gene Expression; Glutathione Transferase; Lead; Metallothionein; Peroxidases; Soil; Soil Pollutants; Suburban Population; Trifolium | 2016 |
Polymorphism of Metallothionein 2A Modifies Lead Body Burden in Workers Chronically Exposed to the Metal.
Topics: Adult; Body Burden; Genetic Predisposition to Disease; Humans; Lead; Male; Metallothionein; Metals, Heavy; Middle Aged; Occupational Exposure; Polymorphism, Single Nucleotide; Regression Analysis; Tissue Distribution | 2016 |
Thermodynamics of Pb(ii) and Zn(ii) binding to MT-3, a neurologically important metallothionein.
Topics: Humans; Kinetics; Lead; Metallothionein; Neurons; Protein Binding; Thermodynamics; Zinc | 2016 |
Exploring the fungal protein cadre in the biosynthesis of PbSe quantum dots.
Topics: Aspergillus; Biomass; Chelating Agents; Fungal Proteins; Lead; Metallothionein; Oxalates; Phytochelatins; Quantum Dots; Reactive Oxygen Species; Seawater; Selenium Compounds; Sulfhydryl Compounds; Superoxide Dismutase | 2017 |
Prevention of gastrointestinal lead poisoning using recombinant Lactococcus lactis expressing human metallothionein-I fusion protein.
Topics: Administration, Oral; Animals; Brain; Calorimetry; Disease Models, Animal; Gastrointestinal Tract; Genetic Vectors; Glutathione Transferase; Humans; Intestines; Kidney; Lactococcus lactis; Lead; Lead Poisoning; Liver; Male; Metallothionein; Muscle, Skeletal; Plasmids; Rats; Recombinant Proteins; Testis; Thermodynamics; Tissue Distribution | 2016 |
Functional characterization of a type 2 metallothionein isoform (OsMTI-2b) from rice.
Topics: Cadmium; Copper; Escherichia coli; Gene Expression Regulation; Lead; Metallothionein; Nickel; Oryza; Protein Isoforms; Recombinant Fusion Proteins; Zinc | 2016 |
The effect of occupational exposure on pro/antioxidant balance in the blood of non-smoking and smoking smelters with diabetes.
Topics: Adult; Air Pollutants; Arsenic; Cadmium; Diabetes Mellitus; Environmental Monitoring; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Lead; Male; Metallothionein; Metallurgy; Middle Aged; Occupational Exposure; Smoking; Superoxide Dismutase; Young Adult | 2016 |
Lead accumulation and metallothionein content in female rats of different ages and generations after daily intake of Pb-contaminated food.
Topics: Aging; Animal Feed; Animals; Environmental Pollutants; Female; Food Contamination; Lead; Maternal Exposure; Metallothionein; Milk; Organ Specificity; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Tissue Distribution | 2016 |
Metallothionein assisted periplasmic lead sequestration as lead sulfite by Providencia vermicola strain SJ2A.
Topics: Biodegradation, Environmental; Lead; Metallothionein; Providencia | 2017 |
Determination and Evaluation of Metallothionein and Metals in Mugil cephalus (Mullet) from Pontal Bay, Brazil.
Topics: Animals; Bays; Biomarkers; Brazil; Cadmium; Copper; Environmental Monitoring; Gills; Lead; Liver; Metallothionein; Metals, Heavy; Nickel; Smegmamorpha; Water Pollutants, Chemical | 2017 |
Expression of metallothionein in the liver and kidneys of the red deer (Cervus elaphus L.) from an industrial metal smelting area of Poland.
Topics: Animals; Cadmium; Cloning, Molecular; Copper; Deer; Environmental Exposure; Genetic Markers; Industrial Waste; Kidney; Lead; Liver; Metallothionein; Metals, Heavy; Poland; RNA, Messenger; Sequence Alignment; Spectrophotometry, Atomic; Zinc | 2017 |
Effects of sub-chronic exposure to lead (Pb) and ascorbic acid in juvenile rockfish: Antioxidant responses, MT gene expression, and neurotransmitters.
Topics: Acetylcholinesterase; Animals; Antioxidants; Ascorbic Acid; Bass; Brain; Dietary Supplements; Fish Proteins; Gene Expression; Gills; Glutathione; Glutathione Transferase; Lead; Liver; Metallothionein; Muscles; Oxidative Stress; Superoxide Dismutase; Water Pollutants, Chemical | 2017 |
Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines.
Topics: Arsenic; Cadmium; Cell Line; Cell Survival; China; Gene Expression Regulation; Hep G2 Cells; Humans; Keratinocytes; Lead; Metallothionein; Mining; Oryza; Soil Pollutants | 2017 |
Antioxidant Responses, Neurotoxicity, and Metallothionein Gene Expression in Juvenile Korean Rockfish Sebastes schlegelii under Dietary Lead Exposure.
Topics: Animals; Antioxidants; Gills; Lead; Metallothionein; Oxidative Stress; Perciformes; Water Pollutants, Chemical | 2017 |
Yucca schidigera extract modulates the lead-induced oxidative damage, nephropathy and altered inflammatory response and glucose homeostasis in Japanese quails.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Biomarkers; Blood Glucose; Catalase; Coturnix; Deoxyguanosine; Diabetic Nephropathies; Glomerular Filtration Rate; Glucose Transporter Type 2; Glutathione; Homeostasis; Insulin; Kidney; Lead; Malondialdehyde; Metallothionein; Oxidative Stress; Pancreas; Plant Extracts; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Yucca | 2018 |
Assessing lead toxicity in the clam Ruditapes philippinarum: Bioaccumulation and biochemical responses.
Topics: Animals; Biomarkers; Bivalvia; Catalase; Gills; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Lead; Lipid Peroxidation; Metallothionein; Porphobilinogen Synthase; Superoxide Dismutase; Water Pollutants, Chemical | 2018 |
Binding of Cd(II), Pb(II), and Zn(II) to a type 1 metallothionein from maize (Zea mays).
Topics: Binding Sites; Cadmium; Hydrogen-Ion Concentration; Lead; Metallothionein; Recombinant Proteins; Zea mays; Zinc | 2018 |
Implications on the Pb bioaccumulation and metallothionein levels due to dietary and waterborne exposures: The Callinectes danae case.
Topics: Animals; Brachyura; Gills; Hepatopancreas; Lead; Male; Metallothionein; Muscles; Toxicity Tests; Water Pollutants, Chemical | 2018 |
Pb(ii) binding to the brain specific mammalian metallothionein isoform MT3 and its isolated αMT3 and βMT3 domains.
Topics: Amino Acid Sequence; Animals; Brain; Humans; Lead; Matrix Metalloproteinase 16; Metallothionein; Metallothionein 3; Mice; Molecular Sequence Data; Protein Binding; Zinc | 2019 |
Identification of a metallothionein gene in honey bee Apis mellifera and its expression profile in response to Cd, Cu and Pb exposure.
Topics: Animals; Bees; Cadmium; Copper; Hymenoptera; Lead; Metallothionein | 2019 |
Immune response, MT and HSP70 gene expression, and bioaccumulation induced by lead exposure of the marine crab, Charybdis japonica.
Topics: Animals; Brachyura; Dose-Response Relationship, Drug; Female; Gene Expression; HSP70 Heat-Shock Proteins; Lead; Metallothionein; Organ Specificity; Water Pollutants, Chemical | 2019 |
Impact of co-exposure to titanium dioxide nanoparticles and Pb on zebrafish embryos.
Topics: Animals; Biological Availability; Embryo, Nonmammalian; Larva; Lead; Metal Nanoparticles; Metallothionein; Nanoparticles; Titanium; Water Pollutants, Chemical; Zebrafish | 2019 |
Single and joint oxidative stress-related toxicity of sediment-associated cadmium and lead on Bellamya aeruginosa.
Topics: Animals; Biomarkers; Cadmium; Catalase; Ecosystem; Fresh Water; Glutathione Peroxidase; Lead; Malondialdehyde; Metallothionein; Metals, Heavy; Oxidative Stress; Pseudomonas aeruginosa; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
Chronic lead (Pb) exposure results in diminished hemocyte count and increased susceptibility to bacterial infection in Drosophila melanogaster.
Topics: Animals; Bacillus subtilis; Drosophila melanogaster; Environmental Pollutants; Gram-Positive Bacterial Infections; Hemocytes; Hemolymph; Larva; Lead; Metallothionein; Monophenol Monooxygenase | 2019 |
Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae.
Topics: Adsorption; Animals; Behavior, Animal; Biological Availability; Larva; Lead; Locomotion; Metallothionein; Nanoparticles; Suspensions; Titanium; Transcription, Genetic; Water Pollutants, Chemical; Zebrafish | 2019 |
Expression of metallothionein encoding gene bmtA in biofilm-forming marine bacterium Pseudomonas aeruginosa N6P6 and understanding its involvement in Pb(II) resistance and bioremediation.
Topics: Biodegradation, Environmental; Biofilms; Escherichia coli; Lead; Metallothionein; Metals, Heavy; Plankton; Polysaccharides, Bacterial; Pseudomonas aeruginosa | 2019 |
Removal of Pb (II), As (III), and Cr (VI) by nitrogen-starved Papiliotrema laurentii strain RY1.
Topics: Antioxidants; Arsenic; Basidiomycota; Biodegradation, Environmental; Biological Transport; Cadmium; Environmental Pollutants; Gene Expression; Inactivation, Metabolic; Lead; Metallothionein; Metals, Heavy; Microbial Sensitivity Tests; Nitrogen | 2019 |
Cellulose-metallothionein biosorbent for removal of Pb(II) and Zn(II) from polluted water.
Topics: Adsorption; Cellulose; Hydrogen-Ion Concentration; Ions; Kinetics; Lead; Metallothionein; Metals, Heavy; Water; Water Pollutants, Chemical; Water Pollution; Water Purification; Zinc | 2020 |
Lead toxicity on a sentinel species subpopulation inhabiting mangroves with different status conservation.
Topics: Animals; Biomarkers; Brachyura; Brazil; Environmental Monitoring; Gills; Lead; Metallothionein; Sentinel Species; Water Pollutants, Chemical; Wetlands | 2020 |
The association of blood lead levels and renal effects may be modified by genetic combinations of Metallothionein 1A 2A polymorphisms.
Topics: Acetylglucosaminidase; Adult; Biomarkers; Female; Humans; Kidney; Lead; Lead Poisoning; Male; Metallothionein; Middle Aged; Polymorphism, Single Nucleotide; Uric Acid | 2020 |
Effect of metallothionein 1A rs8052394 polymorphism on lead, cadmium, zinc, and aluminum levels in factory workers.
Topics: Adolescent; Adult; Aged; Aluminum; Cadmium; Copper; Female; Genetic Variation; Genotype; Humans; India; Lead; Male; Metal Workers; Metallothionein; Metals, Heavy; Middle Aged; Occupational Exposure; Paint; Polymorphism, Single Nucleotide; Young Adult; Zinc | 2020 |
Hepatotoxic effect of lead and hepatoprotective effect of
Topics: Animals; Cyprinidae; Cytochrome P-450 CYP3A; HSP70 Heat-Shock Proteins; Hydrocharitaceae; Lead; Liver; Metallothionein | 2022 |
Enzymatic and non-enzymatic detoxification in Lycosa terrestris and Pardosa birmanica exposed to single and binary mixture of copper and lead.
Topics: Acetylcholinesterase; Animals; Arthropod Proteins; Bioaccumulation; Carboxylic Ester Hydrolases; Copper; Cytochrome P-450 Enzyme System; Diet; Glutathione; Glutathione Transferase; Lead; Metallothionein; Soil Pollutants; Spiders | 2020 |
Metal concentrations and metallothionein metal detoxification in blue sharks, Prionace glauca L. from the Western North Atlantic Ocean.
Topics: Animals; Atlantic Ocean; Cadmium; Lead; Metallothionein; Sharks | 2021 |
Expression regulation of chitin-binding protein and metal-binding peptide in new Bacillus velezensis: MALDI-TOF MS/MS analysis.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; Chitin; Lead; Metallothionein; Metals; Molecular Weight; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2021 |
Effective and stable adsorptive removal of Cadmium(II) and Lead(II) using selenium nanoparticles modified by microbial SmtA metallothionein.
Topics: Adsorption; Cadmium; Lead; Ligands; Metallothionein; Nanoparticles; Selenium; Wastewater; Water; Water Pollutants, Chemical | 2022 |
Heavy Metal Bioaccumulation and Oxidative Stress Profile in Brachidontes pharaonis (Bivalvia: Mytilidae) from the Tunisian Coast: Insight into Its Relevance as Bioindicator of Marine Pollution.
Topics: Animals; Bioaccumulation; Biomarkers; Bivalvia; Catalase; Environmental Biomarkers; Glutathione Peroxidase; Lead; Metallothionein; Metals, Heavy; Mytilidae; Oxidative Stress; Superoxide Dismutase; Water Pollutants, Chemical | 2022 |
Identification of critical genes associated with lead exposure based on
Topics: Cell Cycle Proteins; Computational Biology; Gene Expression Profiling; Humans; Lead; Leukocytes, Mononuclear; Membrane Proteins; Metallothionein; Nerve Tissue Proteins; Protein Interaction Maps; Tumor Suppressor Proteins | 2023 |
Pb exposure causes non-linear accumulation of Pb in D. melanogaster controlled by metallothionein B and exerts ecological effects.
Topics: Animals; Drosophila melanogaster; Ecosystem; Humans; Lead; Metallothionein; Metals, Heavy | 2023 |