Page last updated: 2024-08-17

lawsone and juglone

lawsone has been researched along with juglone in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's3 (11.54)18.2507
2000's4 (15.38)29.6817
2010's13 (50.00)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Divo, AA; Lin, TS; Sartorelli, AC; Xu, SP; Zhu, LY1
Douglas, KT; Guedes, RC; Iley, J; Jaffar, M; Moreira, R; Valente, C1
Carroll, PJ; DuHadaway, JB; Jaller, D; Kumar, S; LaLonde, JM; Malachowski, WP; Metz, R; Muller, AJ; Prendergast, GC1
Fischer, TC; Gosch, C; Gselmann, M; Mirbeth, B; Stich, K; Thallmair, V1
Balaji, R; Dinesh, R; Kandhasamy, S; Karunagaran, D; Mathivanan, N; Mukesh, D; Perumal, PT; Shruthy, S; Shweta, S; Sreelatha, T1
Epifano, F; Fiorito, S; Genovese, S; Hill, K; Leonhardt, M; Schulze, A; Taddeo, VA1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Afraj, SN; Barve, BD; Ho, HO; Hung, CC; Kuo, LY; Kuo, YH; Lin, ZH; Shen, CC1
Cui, J; Jia, J1
Brunmark, A; Ollinger, K1
Cohen, GM; d'Arcy Doherty, M; Rodgers, A1
Hasegawa, M; Hashimoto, Y; Kamei, H; Koide, T; Kojima, T1
Comandini, O; Curreli, N; Massa, L; Rinaldi, A; Rinaldi, AC; Rufo, A; Sanjust, E; Sollai, F1
Avila, J; Hernández, F; Martín, CP; Moreno, FJ; Santa-María, I1
Karcz, W; Kot, M; Zaborska, W1
Ji, Q; Jin, R; Liu, G; Lv, H; Wang, J; Zhou, J1
Doong, RA; Lee, CC; Lien, CM1
Aravind, UK; Aravindakumar, CT; Belloni, J; Marignier, JL; Menachery, SP; Sreekanth, R1
Adam, V; Babula, P; Jampilek, J; Pekarek, T; Vaverkova, V; Vrana, O1
Kim, SY; Lee, TH; Moon, EY; Wahedi, HM1
Chinchilla, N; Durán, AG; Macías, FA; Molinillo, JM1
Anaissi-Afonso, L; Ayra-Plasencia, J; Estévez-Braun, A; Fernández-Pérez, L; García-Luis, J; Lorenzo-Castrillejo, I; Machín, F; Martín-Rodríguez, P; Oramas-Royo, S1
Margina, D; Mihai, DP; Nicorescu, IM; Nitulescu, G; Nitulescu, GM; Olaru, OT; Ungurianu, A; Zanfirescu, A1
de Carvalho da Silva, F; de Freitas, PP; Dos Santos Guimarães, I; Ferreira, VF; Gimba, ERP; Moreira, CS; Ribeiro, RCB; Rocha, DR1
Barnaś, K; Dziuba, J; Kapsiak, M; Nowicka, B; Suchoń, A; Walczak, J1
Benfodda, Z; Duvauchelle, V; Majdi, C; Meffre, P1

Reviews

1 review(s) available for lawsone and juglone

ArticleYear
An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Anti-Bacterial Agents; Bacteria; Coordination Complexes; Humans; Naphthoquinones

2023

Other Studies

25 other study(ies) available for lawsone and juglone

ArticleYear
Synthesis and antimalarial activity of 2-aziridinyl- and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Animals; Antimalarials; Aziridines; Chemical Phenomena; Chemistry; Naphthoquinones; Plasmodium falciparum; Structure-Activity Relationship

1991
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.
    Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15

    Topics: Cathepsin B; Cysteine; Cysteine Proteinase Inhibitors; Models, Molecular; Molecular Structure; Naphthoquinones; Pancreatic Elastase; Papain

2007
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Computer Simulation; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Mice, Knockout; Mice, Nude; Models, Molecular; Molecular Structure; Naphthoquinones; Pyrones; Stereoisomerism; Structure-Activity Relationship; Vitamin K 3

2008
Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
    Journal of agricultural and food chemistry, 2012, Dec-12, Volume: 60, Issue:49

    Topics: Agrochemicals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Drug Stability; Erwinia amylovora; Flowers; Germination; Hydrogen-Ion Concentration; Malus; Microbial Sensitivity Tests; Naphthoquinones; Plant Diseases; Quinones; Toxicity Tests

2012
Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives.
    Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Candida albicans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Drug Screening Assays, Antitumor; Fluconazole; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Structure-Activity Relationship

2014
Plumbagin, Juglone, and Boropinal as Novel TRPA1 Agonists.
    Journal of natural products, 2016, Apr-22, Volume: 79, Issue:4

    Topics: Animals; Ankyrins; Calcium; Coumarins; Female; Ganglia, Spinal; HEK293 Cells; Humans; Male; Mice; Molecular Structure; Naphthoquinones; Phenylpropionates; Sensory Receptor Cells; Transient Receptor Potential Channels; TRPA1 Cation Channel

2016
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
Synthesis, biological evaluation, and correlation of cytotoxicity versus redox potential of 1,4-naphthoquinone derivatives.
    Bioorganic & medicinal chemistry letters, 2021, 06-01, Volume: 41

    Topics: Antineoplastic Agents; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; KB Cells; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Structure-Activity Relationship; Topoisomerase I Inhibitors

2021
Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Animals; Binding Sites; Catalytic Domain; Cell Survival; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Evaluation, Preclinical; Humans; Hydrogen Bonding; Molecular Docking Simulation; Naphthoquinones; Protease Inhibitors; SARS-CoV-2; Structure-Activity Relationship; Vero Cells; Viral Matrix Proteins

2021
Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Survival; Dicumarol; Glutathione; Liver; Male; Methionine Sulfoximine; Mitochondria, Liver; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1991
Mechanisms of toxicity of 2- and 5-hydroxy-1,4-naphthoquinone; absence of a role for redox cycling in the toxicity of 2-hydroxy-1,4-naphthoquinone to isolated hepatocytes.
    Journal of applied toxicology : JAT, 1987, Volume: 7, Issue:2

    Topics: Animals; Antifungal Agents; Glutathione; In Vitro Techniques; Liver; Male; Microsomes, Liver; NADP; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1987
Inhibition of cell growth in culture by quinones.
    Cancer biotherapy & radiopharmaceuticals, 1998, Volume: 13, Issue:3

    Topics: Anthraquinones; Antineoplastic Agents; Arbutin; Cell Division; Colonic Neoplasms; Humans; Naphthoquinones; Quinones; Tumor Cells, Cultured; Xanthenes; Xanthones

1998
Effects of plant-derived naphthoquinones on the growth of Pleurotus sajor-caju and degradation of the compounds by fungal cultures.
    Journal of basic microbiology, 2001, Volume: 41, Issue:5

    Topics: Biodegradation, Environmental; Culture Media; Microbial Sensitivity Tests; Naphthoquinones; Plants; Pleurotus

2001
Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers.
    Biochemistry, 2004, Mar-16, Volume: 43, Issue:10

    Topics: Amino Acid Motifs; Amino Acid Sequence; Benzoquinones; Cyclic AMP-Dependent Protein Kinases; Humans; Molecular Sequence Data; Naphthoquinones; Neurofibrillary Tangles; Peptide Fragments; Phosphorylation; Polymers; Protein Binding; Protein Processing, Post-Translational; Quinones; Recombinant Proteins; tau Proteins; Tubulin; Ubiquinone; Vitamin K 1; Vitamin K 3

2004
5-Hydroxy-1,4-naphthoquinone (juglone) and 2-hydroxy-1,4-naphthoquinone (lawsone) influence on jack bean urease activity: Elucidation of the difference in inhibition activity.
    Bioorganic chemistry, 2010, Volume: 38, Issue:3

    Topics: Canavalia; Catalase; Dithiothreitol; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Naphthoquinones; Urease

2010
Accelerated removal of Sudan dye by Shewanella oneidensis MR-1 in the presence of quinones and humic acids.
    World journal of microbiology & biotechnology, 2013, Volume: 29, Issue:9

    Topics: Aerobiosis; Anthraquinones; Coloring Agents; Humic Substances; Microscopy, Electron, Scanning; Naphthols; Naphthoquinones; Oxidation-Reduction; Shewanella; Solubility

2013
Enhanced dechlorination of carbon tetrachloride by Geobacter sulfurreducens in the presence of naturally occurring quinones and ferrihydrite.
    Chemosphere, 2014, Volume: 97

    Topics: Biodegradation, Environmental; Carbon Tetrachloride; Ferric Compounds; Ferrous Compounds; Geobacter; Hazardous Substances; Naphthoquinones; Oxidation-Reduction; Quinones; Solvents

2014
Oxidation reactions of hydroxy naphthoquinones: mechanistic investigation by LC-Q-TOF-MS analysis.
    International journal of radiation biology, 2014, Volume: 90, Issue:6

    Topics: Chromatography, Liquid; Hydroxyl Radical; Models, Chemical; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Pulse Radiolysis; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Ultraviolet Rays

2014
The study of naphthoquinones and their complexes with DNA by using Raman spectroscopy and surface enhanced Raman spectroscopy: new insight into interactions of DNA with plant secondary metabolites.
    BioMed research international, 2014, Volume: 2014

    Topics: DNA; DNA, B-Form; Naphthoquinones; Plants; Reactive Oxygen Species; Secondary Metabolism; Spectrum Analysis, Raman

2014
Juglone up-regulates sirt1 in skin cells under normal and UVB irradiated conditions.
    Journal of dermatological science, 2016, Volume: 81, Issue:3

    Topics: Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Keratinocytes; Naphthoquinones; NIMA-Interacting Peptidylprolyl Isomerase; Resveratrol; Signal Transduction; Sirtuin 1; Skin; Stilbenes; Ultraviolet Rays; Up-Regulation

2016
Influence of lipophilicity in O-acyl and O-alkyl derivatives of juglone and lawsone: a structure-activity relationship study in the search for natural herbicide models.
    Pest management science, 2018, Volume: 74, Issue:3

    Topics: Avena; Echinochloa; Herbicides; Lolium; Naphthoquinones; Plant Weeds; Structure-Activity Relationship

2018
Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity.
    ACS chemical biology, 2018, 08-17, Volume: 13, Issue:8

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Mitochondria; Molecular Structure; Naphthoquinones; Oxidative Stress; Saccharomyces cerevisiae; Staphylococcus aureus; Structure-Activity Relationship

2018
Discovery of natural naphthoquinones as sortase A inhibitors and potential anti-infective solutions against Staphylococcus aureus.
    Drug development research, 2019, Volume: 80, Issue:8

    Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Catalytic Domain; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enterococcus faecalis; Inhibitory Concentration 50; Models, Molecular; Molecular Docking Simulation; Naphthoquinones; Protein Binding; Staphylococcus aureus; Staphylococcus epidermidis

2019
(3,3'-Methylene)bis-2-hydroxy-1,4-naphthoquinones induce cytotoxicity against DU145 and PC3 cancer cells by inhibiting cell viability and promoting cell cycle arrest.
    Molecular biology reports, 2021, Volume: 48, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Male; Naphthoquinones; PC-3 Cells; Prostatic Neoplasms

2021
Impact of cytotoxic plant naphthoquinones, juglone, plumbagin, lawsone and 2-methoxy-1,4-naphthoquinone, on Chlamydomonas reinhardtii reveals the biochemical mechanism of juglone toxicity by rapid depletion of plastoquinol.
    Plant physiology and biochemistry : PPB, 2023, Volume: 197

    Topics: Antioxidants; Chlamydomonas reinhardtii; Naphthoquinones; Plants; Reactive Oxygen Species

2023