Page last updated: 2024-08-17

lawsone and 1,4-naphthoquinone

lawsone has been researched along with 1,4-naphthoquinone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Dunn, WJ; Hodnett, EM; Marrs, P; Wongwiechintana, C1
Cordingley, MG; Graham, PL; Reamer, RA; Singh, SB1
Douglas, KT; Guedes, RC; Iley, J; Jaffar, M; Moreira, R; Valente, C1
Carroll, PJ; DuHadaway, JB; Jaller, D; Kumar, S; LaLonde, JM; Malachowski, WP; Metz, R; Muller, AJ; Prendergast, GC1
Chou, CJ; Inks, ES; Josey, BJ; Wen, X1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Cui, J; Jia, J1
Brunmark, A; Ollinger, K1
Buffinton, G; Cadenas, E1
Clarke, DT; Jones, GR; Martin, MM1
Lingens, F; Rettenmaier, H; Wessendorf, J1
Karcz, W; Ludynia, M; Rudnicka, M1
Jekabsone, A; Kuseliauskyte, J; Majiene, D; Stimbirys, A1

Other Studies

13 other study(ies) available for lawsone and 1,4-naphthoquinone

ArticleYear
Substituted 1,4-naphthoquinones vs. the ascitic sarcoma 180 of mice.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:4

    Topics: Animals; Lethal Dose 50; Magnetic Resonance Spectroscopy; Mathematics; Mice; Naphthoquinones; Sarcoma 180; Structure-Activity Relationship

1983
Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.
    Bioorganic & medicinal chemistry letters, 2001, Dec-17, Volume: 11, Issue:24

    Topics: 3C Viral Proteases; Cysteine Endopeptidases; Naphthoquinones; Protease Inhibitors; Structure-Activity Relationship; Viral Proteins

2001
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.
    Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15

    Topics: Cathepsin B; Cysteine; Cysteine Proteinase Inhibitors; Models, Molecular; Molecular Structure; Naphthoquinones; Pancreatic Elastase; Papain

2007
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Computer Simulation; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Mice, Knockout; Mice, Nude; Models, Molecular; Molecular Structure; Naphthoquinones; Pyrones; Stereoisomerism; Structure-Activity Relationship; Vitamin K 3

2008
Structure-activity relationship study of vitamin k derivatives yields highly potent neuroprotective agents.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Base Sequence; Cell Line; DNA Primers; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neuroprotective Agents; Oxidative Stress; Real-Time Polymerase Chain Reaction; Structure-Activity Relationship; Vitamin K

2013
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Animals; Binding Sites; Catalytic Domain; Cell Survival; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Evaluation, Preclinical; Humans; Hydrogen Bonding; Molecular Docking Simulation; Naphthoquinones; Protease Inhibitors; SARS-CoV-2; Structure-Activity Relationship; Vero Cells; Viral Matrix Proteins

2021
Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Survival; Dicumarol; Glutathione; Liver; Male; Methionine Sulfoximine; Mitochondria, Liver; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1991
Reduction of ferrylmyoglobin to metmyoglobin by quinonoid compounds.
    Chemico-biological interactions, 1988, Volume: 66, Issue:3-4

    Topics: Benzoquinones; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Hemeproteins; Hydrogen Peroxide; Kinetics; Metmyoglobin; Naphthoquinones; Oxidation-Reduction; Quinones; Spectrophotometry

1988
The anti-sickling drug lawsone (2-OH-1,4-naphthoquinone) protects sickled cells against membrane damage.
    Biochemical and biophysical research communications, 1986, Sep-14, Volume: 139, Issue:2

    Topics: Erythrocyte Membrane; Hematoporphyrins; Hemolysis; Humans; Naphthoquinones; Photochemistry

1986
Degradation of lawsone by Pseudomonas putida L2.
    Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:10

    Topics: Biotransformation; Cell-Free System; Chromatography, Thin Layer; Mixed Function Oxygenases; Naphthoquinones; Pseudomonas; Spectrophotometry, Ultraviolet

1985
Effects of Naphthazarin (DHNQ) Combined with Lawsone (NQ-2-OH) or 1,4-Naphthoquinone (NQ) on the Auxin-Induced Growth of
    International journal of molecular sciences, 2019, Apr-11, Volume: 20, Issue:7

    Topics: Cotyledon; Indoleacetic Acids; Naphthoquinones; Oxidative Stress; Plant Growth Regulators; Zea mays

2019
Comparison of the Effect of Native 1,4-Naphthoquinones Plumbagin, Menadione, and Lawsone on Viability, Redox Status, and Mitochondrial Functions of C6 Glioblastoma Cells.
    Nutrients, 2019, Jun-07, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Glioblastoma; Mitochondria; Naphthoquinones; Oxidants; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Phytotherapy; Plant Extracts; Rats; Reactive Oxygen Species; Uncoupling Agents; Vitamin K 3

2019