Page last updated: 2024-08-26

lavendamycin and streptonigrin

lavendamycin has been researched along with streptonigrin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's8 (50.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hibino, S; Ichikawa, M; Motoshima, A; Okazaki, M; Sato, K; Ueki, H1
Boger, DL; Drake, SD; Kitos, PA; Mitscher, LA; Thompson, SC; Yasuda, M1
Balitz, DM; Bradner, WT; Bush, JA; Doyle, TW; Nettleton, DE; O'Herron, FA1
Abe, N; Enoki, N; Munekata, M; Nakakita, Y; Nakamura, T; Takeo, S; Uchida, H1
Abe, N; Enoki, N; Munekata, M; Nakakita, Y; Nakamura, T; Uchida, H1
Abraham, RT; Behforouz, M; Cai, W; Fang, Y; Linardic, CM; Richardson, DA1
DeShong, P; McElroy, WT1
Behforouz, M; Behforouz, NC; Briere, D; Cai, W; Jung, JY; Katen, KS; Lucas, JS; Stocksdale, MG; Wang, A1
Behforouz, M; Cai, W; Chenault, DV; Erasga, NO; Knuckles, KA; Ragains, JR; Seradj, H1
Beall, HD; Behforouz, M; Cai, W; Ebrahimian, GR; Gerdes, JM; Hassani, M; Holley, DC; Lineswala, JP; Maharjan, BR; Marvin, CC; Mohammadi, F; Seradj, H; Stocksdale, MG1
Ahmadian, M; Al-Anzi, CH; Baty, DE; Behforouz, M; Behforouz, NC; Cai, W; Etling, MR; Gu, Z; Merriman, RL; Mohammadi, F; Stocksdale, MG; Swiftney, TM; Tanzer, LR1
Beall, HD; Behforouz, M; Cai, W; Gerdes, JM; Hassani, M; Holley, DC; Holloway, WG; Koelsch, KH; Lineswala, JP; Olang, F; Rose, AS1
England, DB; Padwa, A1
De Kimpe, N; Padwa, A; Verniest, G; Wang, X1
Beall, HD; Behforouz, M; Cai, W; Charkhzarrin, S; Eads, TJ; Hassani, M; Hermann, NG; Karki, R; Koelsch, KH; Lineswala, JP; Lucas, JS; Mirzaei, H; Olang, F; Rose, AS; Sedighi, M; Seradj, H; Walter, ED; York, JS1
Cong, FS; Lin, S; Xia, X; Xia, XX; Zhong, JJ1

Other Studies

16 other study(ies) available for lavendamycin and streptonigrin

ArticleYear
In vitro oxidation of the 8-hydroxyquinoline moiety with metabolic activation system to a mutagenic quinoloquinone compound of lavendamycin analogs.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:3

    Topics: Animals; Biotransformation; Hydroxyquinolines; Male; Mice; Mutagens; Oxidation-Reduction; Oxyquinoline; Streptonigrin

1986
Streptonigrin and lavendamycin partial structures. Probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry, Physical; Leukemia L1210; Melanoma; Mice; Microbial Sensitivity Tests; Quinolines; Streptonigrin; Structure-Activity Relationship

1987
Isolation of lavendamycin, a new antibiotic from Streptomyces lavendulae.
    The Journal of antibiotics, 1982, Volume: 35, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Bacteria; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Leukemia P388; Mice; Streptomyces; Streptonigrin

1982
Novel cytocidal compounds, oxopropalines from Streptomyces sp. G324 producing lavendamycin. I. Taxonomy of the producing organism, fermentation, isolation and biological activities.
    The Journal of antibiotics, 1993, Volume: 46, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Carbolines; Chromatography, High Pressure Liquid; Fermentation; Humans; Mice; Streptomyces; Streptonigrin; Tumor Cells, Cultured

1993
Novel cytocidal compounds, oxopropalines from Streptomyces sp. G324 producing lavendamycin. II. Physico-chemical properties and structure elucidations.
    The Journal of antibiotics, 1993, Volume: 46, Issue:11

    Topics: Antibiotics, Antineoplastic; Carbolines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry; Streptomyces; Streptonigrin

1993
Characterization of the cytotoxic activities of novel analogues of the antitumor agent, lavendamycin.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Flow Cytometry; G2 Phase; Humans; Immunoblotting; Mitosis; Models, Chemical; Phosphorylation; Proto-Oncogene Proteins p21(ras); Streptonigrin; Time Factors; Tumor Suppressor Protein p53

2003
Siloxane-based cross-coupling of bromopyridine derivatives: studies for the synthesis of streptonigrin and lavendamycin.
    Organic letters, 2003, Dec-11, Volume: 5, Issue:25

    Topics: Antibiotics, Antineoplastic; Molecular Structure; Pyridines; Siloxanes; Streptonigrin

2003
Novel lavendamycin analogues as potent HIV-reverse transcriptase inhibitors: synthesis and evaluation of anti-reverse transcriptase activity of amide and ester analogues of lavendamycin.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Amides; Animals; Cells, Cultured; Dideoxynucleotides; Drug Synergism; Esters; HIV Reverse Transcriptase; Humans; Mice; Reverse Transcriptase Inhibitors; Streptonigrin; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine

2003
Total synthesis of novel 6-substituted lavendamycin antitumor agents.
    Organic letters, 2004, Feb-19, Volume: 6, Issue:4

    Topics: Antibiotics, Antineoplastic; Catalysis; Indicators and Reagents; Molecular Structure; Streptomyces; Streptonigrin; Structure-Activity Relationship

2004
Novel lavendamycin analogues as antitumor agents: synthesis, in vitro cytotoxicity, structure-metabolism, and computational molecular modeling studies with NAD(P)H:quinone oxidoreductase 1.
    Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Drug Screening Assays, Antitumor; Electrochemistry; Humans; Hydrogen Bonding; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Streptonigrin; Structure-Activity Relationship

2005
Synthesis and evaluation of antitumor activity of novel N-acyllavendamycin analogues and quinoline-5,8-diones.
    Bioorganic & medicinal chemistry, 2007, Jan-01, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Female; Mice; Mice, Inbred C57BL; Mice, Nude; Molecular Structure; Neoplasms; Quinolines; Rats; Stereoisomerism; Streptonigrin; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2007
Lavendamycin antitumor agents: structure-based design, synthesis, and NAD(P)H:quinone oxidoreductase 1 (NQO1) model validation with molecular docking and biological studies.
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cytochromes c; Drug Screening Assays, Antitumor; Humans; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Protein Binding; Streptonigrin; Structure-Activity Relationship

2008
Gold-catalyzed cycloisomerization of N-Propargylindole-2-carboxamides: application toward the synthesis of lavendamycin analogues.
    Organic letters, 2008, Aug-21, Volume: 10, Issue:16

    Topics: Alkynes; Carbolines; Catalysis; Cyclization; Gold Compounds; Indoles; Molecular Structure; Organometallic Compounds; Palladium; Stereoisomerism; Streptonigrin

2008
Heteroaryl cross-coupling as an entry toward the synthesis of lavendamycin analogues: a model study.
    The Journal of organic chemistry, 2010, Jan-15, Volume: 75, Issue:2

    Topics: Antibiotics, Antineoplastic; Catalysis; Cross-Linking Reagents; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Palladium; Quinolines; Stereoisomerism; Streptonigrin

2010
Synthesis, metabolism and in vitro cytotoxicity studies on novel lavendamycin antitumor agents.
    Bioorganic & medicinal chemistry, 2010, Mar-01, Volume: 18, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; NAD(P)H Dehydrogenase (Quinone); Recombinant Proteins; Streptonigrin; Structure-Activity Relationship

2010
Significance of agitation-induced shear stress on mycelium morphology and lavendamycin production by engineered Streptomyces flocculus.
    Applied microbiology and biotechnology, 2014, Volume: 98, Issue:10

    Topics: Antibiotics, Antineoplastic; Mechanical Phenomena; Oxygen; Streptomyces; Streptonigrin; Stress, Mechanical

2014