Compounds > lauric acid

lauric acid and heme

lauric acid has been researched along with heme in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (64.29)18.2507
2000's3 (21.43)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyle, JM; Gibson, CF; Lian, LY; Modi, S; Primrose, WU; Roberts, GC1
Bambal, RB; Hanzlik, RP1
Roberts, GC1
Feyereisen, R; Murataliev, MB1
Alterman, MA; Bambal, RB; Chaurasia, CS; Hanzlik, RP; Lu, P1
Alayrac, C; Durst, F; Helvig, C; Koop, D; Mioskowski, C; Poullain, D; Salaün, JP1
Macdonald, ID; Munro, AW; Smith, WE1
Fisher, MB; Fujii-Kuriyama, Y; Rettie, AE; Yokotani, N; Zheng, YM1
Chapman, SK; Chumanov, GD; Hanzlik, RP; Munro, AW; Noble, MA; Quaroni, L; Turner, KL1
Baer, BR; Henne, KR; Kneller, MB; Kunze, KL; Rettie, AE; Zheng, YM1
Baer, BR; Cheesman, MJ; Gillam, EM; Rettie, AE; Zheng, YM1
Feyereisen, R; Girvan, HM; Guzov, VM; Munro, AW; Murataliev, M; Noble, MA; Smith, SJ; Smith, WE1
Cheesman, MR; Fisher, K; Girvan, HM; Levy, CW; Leys, D; Munro, AW; Rigby, SE; Williams, P1
Chavez, G; Cheruzel, LE; Dao, T; Dwaraknath, S; Mahadevan, S; Mullen, S; Nguyen, A; Nguyen, D; Nguyen, TA; Tran, NH1

Reviews

1 review(s) available for lauric acid and heme

ArticleYear
The other kind of biological NMR--studies of enzyme-substrate interactions.
    Neurochemical research, 1996, Volume: 21, Issue:9

    Topics: beta-Lactamases; Binding Sites; Chloramphenicol O-Acetyltransferase; Cytochrome P-450 Enzyme System; Enzymes; Heme; Humans; Lauric Acids; Magnetic Resonance Spectroscopy; Models, Molecular

1996

Other Studies

13 other study(ies) available for lauric acid and heme

ArticleYear
NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam.
    Biochemistry, 1995, Jul-18, Volume: 34, Issue:28

    Topics: Bacillus megaterium; Bacterial Proteins; Binding Sites; Camphor 5-Monooxygenase; Cytochrome P-450 Enzyme System; Electrochemistry; Heme; Iron; Lauric Acids; Magnetic Resonance Spectroscopy; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Protein Conformation; Substrate Specificity

1995
Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane.
    Biochemical and biophysical research communications, 1996, Feb-15, Volume: 219, Issue:2

    Topics: Allosteric Regulation; Binding Sites; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dicarboxylic Acids; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Heme; Kinetics; Lauric Acids; Ligands; Mixed Function Oxygenases; Recombinant Fusion Proteins; Substrate Specificity

1996
Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain.
    Biochemistry, 1996, Nov-26, Volume: 35, Issue:47

    Topics: Bacterial Proteins; Carbon Monoxide; Catalysis; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Transport; Escherichia coli; Fatty Acids; Flavoproteins; Heme; Hydroxylation; Lauric Acids; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Spectrometry, Fluorescence

1996
Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation.
    Archives of biochemistry and biophysics, 1997, Jan-01, Volume: 337, Issue:1

    Topics: Animals; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Heme; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Structure-Activity Relationship

1997
Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase.
    The Journal of biological chemistry, 1997, Jan-03, Volume: 272, Issue:1

    Topics: Acetylene; Animals; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Heme; Lauric Acids; Microsomes; Mixed Function Oxygenases; Plant Proteins; Plants; Rabbits; Structure-Activity Relationship

1997
Fatty acid-induced alteration of the porphyrin macrocycle of cytochrome P450 BM3.
    Biophysical journal, 1998, Volume: 74, Issue:6

    Topics: Bacterial Proteins; Binding Sites; Cytochrome P-450 Enzyme System; Heme; Lauric Acids; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Palmitic Acid; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman

1998
Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.
    Biochemistry, 1998, Sep-15, Volume: 37, Issue:37

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Cytochrome P-450 Enzyme System; Heme; Humans; Hydroxylation; Insecta; Lauric Acids; Mutagenesis, Site-Directed; Proline; Rabbits; Rats; Serine; Steroid Hydroxylases; Testosterone

1998
Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3.
    Biochemistry, 1998, Nov-10, Volume: 37, Issue:45

    Topics: Arachidonic Acid; Bacterial Proteins; Binding Sites; Catalysis; Circular Dichroism; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids; Heme; Imidazoles; Kinetics; Lauric Acids; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Protein Structure, Tertiary; Spectrophotometry, Ultraviolet; Substrate Specificity

1998
Covalent heme binding to CYP4B1 via Glu310 and a carbocation porphyrin intermediate.
    Biochemistry, 2003, Apr-22, Volume: 42, Issue:15

    Topics: Aryl Hydrocarbon Hydroxylases; Dimerization; Glutamic Acid; Heme; Lauric Acids; Mutation; Oxygen; Porphyrins

2003
Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group.
    Archives of biochemistry and biophysics, 2003, Aug-01, Volume: 416, Issue:1

    Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Benzoflavones; Biochemistry; Cell Membrane; Enzyme Stability; Escherichia coli; Gene Expression; Heme; Lauric Acids; Ligands; Mass Spectrometry; Molecular Sequence Data; Protein Engineering; Protein Processing, Post-Translational; Rabbits; Recombinant Proteins

2003
Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.
    Drug metabolism reviews, 2007, Volume: 39, Issue:2-3

    Topics: Animals; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Cytochromes b5; Electron Transport; Flavin-Adenine Dinucleotide; Flavins; Heme; Houseflies; Kinetics; Lauric Acids; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Conformation; Spectrophotometry, Ultraviolet; Substrate Specificity

2007
Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
    The Biochemical journal, 2010, Apr-14, Volume: 427, Issue:3

    Topics: Arachidonic Acid; Bacterial Proteins; Crystallography; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Esters; Glutamic Acid; Heme; Kinetics; Lauric Acids; Mutagenesis, Site-Directed; Mutation; NADPH-Ferrihemoprotein Reductase; Potentiometry; Protein Structure, Tertiary; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Substrate Specificity

2010
An efficient light-driven P450 BM3 biocatalyst.
    Journal of the American Chemical Society, 2013, Oct-02, Volume: 135, Issue:39

    Topics: Bacillus megaterium; Bacterial Proteins; Coordination Complexes; Cytochrome P-450 Enzyme System; Enzyme Stability; Heme; Hydroxylation; Lauric Acids; Light; Models, Molecular; NADPH-Ferrihemoprotein Reductase; Photosensitizing Agents; Ruthenium

2013