lauric acid and clofibrate

lauric acid has been researched along with clofibrate in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's9 (47.37)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Knickle, LC; Renton, KW; Spencer, DF1
Freedman, R; Swinney, DC; Webb, AS1
Itoga, H; Okawa, S; Suga, T; Tamura, H; Watanabe, T1
Aoyama, T; Funae, Y; Gelboin, HV; Gonzalez, FJ; Hardwick, JP; Imaoka, S1
Bernhardt, R; Fujii-Kuriyama, Y; Gotoh, O; Kusunose, E; Kusunose, M; Sogawa, K; Yokotani, N1
Bonner, FW; Gibson, GG; Goldfarb, PS; Makowska, JM1
Levine, WG; Raza, H1
Parafita, MA; Pazo, JA1
André, JC; Caldwell, J; Fournel, S; Magdalou, J; Siest, G; Thomassin, J; Villoutreix, J1
Capdevila, J; Estabrook, RW; Falck, JR; Kim, YR; Manna, S; Martin-Wixtrom, C1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Bains, SK; Gibson, GG1
Gibson, GG; Orton, TC; Tamburini, PP1
Alterman, MA; Chaurasia, CS; Hanzlik, RP; Lu, P1
Hiratsuka, M; Matsuura, T; Sato, M; Suzuki, Y1
Hiratsuka, M; Matsuura, T; Sato, M; Suzuki, Y; Watanabe, E1
Alterman, MA; Bambal, RB; Chaurasia, CS; Hanzlik, RP; Lu, P1
Amichot, M; Bergé, JB; Cuany, A; de Sousa, G; Girard, JP; Lafaurie, M; Rahmani, R; Sabourault, C; Salaün, JP1

Reviews

1 review(s) available for lauric acid and clofibrate

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

18 other study(ies) available for lauric acid and clofibrate

ArticleYear
The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid.
    Biochemical pharmacology, 1992, Aug-04, Volume: 44, Issue:3

    Topics: Animals; Base Sequence; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation; Interferons; Lauric Acids; Male; Microsomes, Liver; Molecular Sequence Data; Poly I-C; Rats; Rats, Inbred Strains; RNA, Messenger

1992
A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase.
    Biochemical pharmacology, 1991, Nov-27, Volume: 42, Issue:12

    Topics: Animals; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Detergents; Enzyme Induction; Fatty Acids; Kinetics; Lauric Acids; Leukotriene B4; Male; Microsomes, Liver; Mixed Function Oxygenases; Naproxen; Oxidation-Reduction; Rats

1991
Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver.
    Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:5

    Topics: Animals; Clofibrate; Hydroxylation; In Vitro Techniques; Lauric Acids; Liver; Male; Microbodies; Microsomes, Liver; Nicardipine; Rats; Rats, Inbred Strains

1991
Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha.
    Journal of lipid research, 1990, Volume: 31, Issue:8

    Topics: Alprostadil; Animals; Blotting, Western; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dinoprost; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Gene Expression; Humans; Hydroxylation; Lauric Acids; Liver; Mixed Function Oxygenases; Palmitic Acid; Palmitic Acids; Rats; Sequence Homology, Nucleic Acid; Vaccinia virus

1990
Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Clofibrate; Cloning, Molecular; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; DNA; Gene Expression; Gene Library; Genes; Isoenzymes; Kidney; Lauric Acids; Male; Mixed Function Oxygenases; Molecular Sequence Data; Organ Specificity; Prostaglandins A; Rabbits; Restriction Mapping; Sequence Homology, Nucleic Acid

1989
Species differences in the hepatic response to a potent peroxisome proliferator.
    Biochemical Society transactions, 1989, Volume: 17, Issue:6

    Topics: Animals; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fibric Acids; Guinea Pigs; Hypolipidemic Agents; Lauric Acids; Liver; Male; Microbodies; Rats; Rats, Inbred Strains; RNA, Messenger; Species Specificity

1989
Clofibrate selectively induces azoreduction of dimethylaminoazobenzene (DAB) by rat liver microsomes.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Aerobiosis; Anaerobiosis; Animals; Biotransformation; Clofibrate; Hydroxylation; Kinetics; Lauric Acids; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains

1986
Synergism of ethanol and clofibrate in the lauric acid hydroxylation.
    Drug and alcohol dependence, 1988, Volume: 21, Issue:2

    Topics: Animals; Clofibrate; Drug Synergism; Ethanol; Hydroxylation; Lauric Acids; Liver; Male; Rats; Rats, Inbred Strains

1988
Structure-dependent induction of bilirubin glucuronidation and lauric acid 12-hydroxylation by arylcarboxylic acids chemically related to clofibrate.
    Biochimica et biophysica acta, 1985, Oct-17, Volume: 842, Issue:2-3

    Topics: Animals; Bilirubin; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Hydroxylation; Kinetics; Lauric Acids; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thermodynamics

1985
Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450.
    Archives of biochemistry and biophysics, 1985, Nov-15, Volume: 243, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Benzphetamine; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Fibric Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Lauric Acids; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains

1985
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Cytochrome P-450 isoenzymes involved in fatty acid metabolism.
    Biochemical Society transactions, 1985, Volume: 13, Issue:5

    Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Cytochromes; Fatty Acids; Hypolipidemic Agents; Isoenzymes; Lauric Acids; Lipids; Liver; Rats

1985
Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid).
    The Biochemical journal, 1982, Apr-01, Volume: 203, Issue:1

    Topics: Animals; Benzphetamine; Catalysis; Clofibrate; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Induction; Kinetics; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1982
Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation.
    Biochemical and biophysical research communications, 1995, Sep-25, Volume: 214, Issue:3

    Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Gas Chromatography-Mass Spectrometry; Hydroxylation; Isoenzymes; Lauric Acids; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Structure-Activity Relationship

1995
Effects of gonadectomy and sex hormones on the induction of hepatic CYP4A by clofibrate in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Electron Transport; Enzyme Induction; Female; Gonadal Steroid Hormones; Hydroxylation; Hypolipidemic Agents; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Orchiectomy; Ovariectomy; Rats; Rats, Wistar

1996
Sex differences in constitutive level of renal lauric acid hydroxylase activities and CYP4A-related proteins in mice.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Animals; Antibodies; Blotting, Western; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dexamethasone; Estradiol; Female; Kidney; Lauric Acids; Male; Mice; Mice, Inbred Strains; Microsomes; Mixed Function Oxygenases; Ovariectomy; Sex Factors; Testosterone

1996
Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation.
    Archives of biochemistry and biophysics, 1997, Jan-01, Volume: 337, Issue:1

    Topics: Animals; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Heme; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Structure-Activity Relationship

1997
Tissue-specific induction and inactivation of cytochrome P450 catalysing lauric acid hydroxylation in the sea bass, Dicentrarchus labrax.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1999, Volume: 122, Issue:2

    Topics: Animals; Bass; Biomarkers; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Fatty Acids, Unsaturated; Hydroxylation; Intestine, Small; Kidney; Kinetics; Lauric Acids; Liver; Microsomes; Organ Specificity; Peroxisome Proliferators; Substrate Specificity

1999