laulimalide and acetonitrile

laulimalide has been researched along with acetonitrile* in 1 studies

Other Studies

1 other study(ies) available for laulimalide and acetonitrile

Article	Year
Synthesis of Linear (Z)-α,β-Unsaturated Esters by Catalytic Cross-Metathesis. The Influence of Acetonitrile. Angewandte Chemie (International ed. in English), 2016, 10-10, Volume: 55, Issue:42 Kinetically controlled catalytic cross-metathesis reactions that generate (Z)-α,β-unsaturated esters selectively are disclosed. A key finding is that the presence of acetonitrile obviates the need for using excess amounts of a more valuable terminal alkene substrates. On the basis of X-ray structure and spectroscopic investigations a rationale for the positive impact of acetonitrile is provided. Transformations leading to various E,Z-dienoates are highly Z-selective as well. Utility is highlighted by application to stereoselective synthesis of the C1-C12 fragment of biologically active natural product (-)-laulimalide. Topics: Acetonitriles; Catalysis; Esters; Kinetics; Macrolides; Molecular Structure	2016

Article

Year

Synthesis of Linear (Z)-α,β-Unsaturated Esters by Catalytic Cross-Metathesis. The Influence of Acetonitrile.

Angewandte Chemie (International ed. in English), 2016, 10-10, Volume: 55, Issue:42

Kinetically controlled catalytic cross-metathesis reactions that generate (Z)-α,β-unsaturated esters selectively are disclosed. A key finding is that the presence of acetonitrile obviates the need for using excess amounts of a more valuable terminal alkene substrates. On the basis of X-ray structure and spectroscopic investigations a rationale for the positive impact of acetonitrile is provided. Transformations leading to various E,Z-dienoates are highly Z-selective as well. Utility is highlighted by application to stereoselective synthesis of the C1-C12 fragment of biologically active natural product (-)-laulimalide.

Topics: Acetonitriles; Catalysis; Esters; Kinetics; Macrolides; Molecular Structure

2016