Page last updated: 2024-09-05

latrepirdine and methylene blue

latrepirdine has been researched along with methylene blue in 5 studies

Compound Research Comparison

Studies
(latrepirdine)
Trials
(latrepirdine)
Recent Studies (post-2010)
(latrepirdine)
Studies
(methylene blue)
Trials
(methylene blue)
Recent Studies (post-2010) (methylene blue)
12675911,0673944,258

Protein Interaction Comparison

ProteinTaxonomylatrepirdine (IC50)methylene blue (IC50)
Chain E, Fibrin beta chainHomo sapiens (human)9.253
integrase, partialHuman immunodeficiency virus 11.958
lens epithelium-derived growth factor p75Homo sapiens (human)1.958
Apoptotic peptidase activating factor 1Homo sapiens (human)15.5
neutrophil cytosol factor 1Homo sapiens (human)0.39
caspase-9 isoform alpha precursorHomo sapiens (human)17
caspase-3 isoform a preproproteinHomo sapiens (human)17
Glutathione reductasePlasmodium falciparum 3D76.4
Amyloid-beta precursor proteinHomo sapiens (human)0.5
Microtubule-associated protein tauHomo sapiens (human)2.2333
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.5
Amine oxidase [flavin-containing] AHomo sapiens (human)0.07
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.5
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ge, S; Guan, J; Lin, JP; Liu, XH; Wang, T; Wu, MB; Yang, LR1
Gura, T1
Akiyama, H; Arai, T; Bachurin, SO; Buchman, VL; Goedert, M; Hasegawa, M; Kametani, F; Ninkina, N; Nonaka, T; Yamashita, M1
Gravitz, L1

Reviews

1 review(s) available for latrepirdine and methylene blue

ArticleYear
Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, May-01, Volume: 169

    Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Drug Discovery; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents

2019

Other Studies

4 other study(ies) available for latrepirdine and methylene blue

ArticleYear
Hope in Alzheimer's fight emerges from unexpected places.
    Nature medicine, 2008, Volume: 14, Issue:9

    Topics: Alzheimer Disease; Cognition; Humans; Indoles; Methylene Blue; Research

2008
New treatments in the pipeline for Alzheimer's.
    The Johns Hopkins medical letter health after 50, 2009, Volume: 21, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Indoles; Methylene Blue

2009
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.
    FEBS letters, 2009, Jul-21, Volume: 583, Issue:14

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Cell Line; Dementia; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Inclusion Bodies; Indoles; Methylene Blue

2009
Drugs: a tangled web of targets.
    Nature, 2011, Jul-13, Volume: 475, Issue:7355

    Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azepines; Clinical Trials as Topic; Disease Progression; Genetic Therapy; Glycogen Synthase Kinase 3; Humans; Indoles; Memantine; Methylene Blue; Molecular Targeted Therapy; Nerve Growth Factor; Neurofibrillary Tangles; Phosphorylation; tau Proteins

2011