lasofoxifene has been researched along with fluconazole in 1 studies
| Studies (lasofoxifene) | Trials (lasofoxifene) | Recent Studies (post-2010) (lasofoxifene) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 88 | 14 | 24 | 9,343 | 721 | 3,664 |
| Protein | Taxonomy | lasofoxifene (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bramson, C; Gardner, M; Milton, A; Ouellet, D; Randinitis, E; Remmers, AE; Roman, D | 1 |
1 trial(s) available for lasofoxifene and fluconazole
| Article | Year |
|---|---|
Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifene.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antifungal Agents; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Paroxetine; Postmenopause; Pyrrolidines; Tetrahydronaphthalenes | 2007 |