Page last updated: 2024-09-05

lasofoxifene and ethinyl estradiol

lasofoxifene has been researched along with ethinyl estradiol in 2 studies

Compound Research Comparison

Studies
(lasofoxifene)
Trials
(lasofoxifene)
Recent Studies (post-2010)
(lasofoxifene)
Studies
(ethinyl estradiol)
Trials
(ethinyl estradiol)
Recent Studies (post-2010) (ethinyl estradiol)
8814249,0701,5661,732

Protein Interaction Comparison

ProteinTaxonomylasofoxifene (IC50)ethinyl estradiol (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.2
Bile salt export pumpHomo sapiens (human)10
Estrogen receptorHomo sapiens (human)0.0035
Glucocorticoid receptorHomo sapiens (human)1.71
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)1.71
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.959
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)5.678
Androgen receptorRattus norvegicus (Norway rat)4.8812
Glycine receptor subunit betaRattus norvegicus (Norway rat)1.71
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)1.71
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.959
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)1.71
Sodium-dependent serotonin transporterHomo sapiens (human)0.054
Sulfotransferase 1A1Homo sapiens (human)0.02
Sodium-dependent dopamine transporter Homo sapiens (human)0.559
Aldehyde oxidaseHomo sapiens (human)0.57
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)3
Estrogen receptor betaHomo sapiens (human)0.0129

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arriola, MW; Brown, TA; Cameron, KO; Cole, MJ; Crawford, DT; Da Silva Jardine, P; Ebbinghaus, CF; Elliott, NC; Gauthier, JW; Ke, HZ; Newhouse, BN; Nickerson, DF; Pan, LC; Pirie, CM; Qi, H; Reinhold, AR; Rosati, RL; Simmons, HA; Sweetnam, PM; Thompson, DD; Tjoa, CM; Tkalcevic, GT; Toler, SM1
Armamento-Villareal, R; Brodt, MD; Caruso, PL; Civelli, M; Civitelli, R; Galbiati, E; Halstead, LR; Mueller, C; Napoli, N; Nawaz, A; Sheikh, S; Silva, MJ1

Other Studies

2 other study(ies) available for lasofoxifene and ethinyl estradiol

ArticleYear
Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene.
    Journal of medicinal chemistry, 1998, Jul-30, Volume: 41, Issue:16

    Topics: Administration, Oral; Animals; Biological Availability; Bone Density; Breast Neoplasms; Cell Division; Cholesterol; Estrogen Antagonists; Ethinyl Estradiol; Female; Humans; Hypolipidemic Agents; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Pyrrolidines; Rats; Receptors, Estrogen; Tetrahydronaphthalenes; Tumor Cells, Cultured; Uterus

1998
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Benzopyrans; Biomechanical Phenomena; Blood; Body Composition; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Cholesterol; Compressive Strength; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Femur; Femur Neck; Lumbar Vertebrae; Organ Size; Osteoclasts; Osteogenesis; Ovariectomy; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Tibia; Tomography, X-Ray Computed; Triglycerides; Uterus; Weight-Bearing

2005