lariciresinol and conidendrin

lariciresinol has been researched along with conidendrin* in 1 studies

Other Studies

1 other study(ies) available for lariciresinol and conidendrin

Article	Year
Cytochrome P450 3A4 inhibitory constituents of the wood of Taxus yunnanensis. Journal of natural products, 2011, Jan-28, Volume: 74, Issue:1 From the aqueous extract of the wood of Taxus yunnanensis, which showed cytochrome P450 3A4 (CYP3A4) inhibition, a new isoflavan [(3S,4R)-4'-hydroxy-6,3'-dimethoxyisoflavan-4-ol (1)], a new degraded lignan [2,3-bis(hydroxymethyl)-7-hydroxy-6-methoxy-1-tetralone (2)], and a new lignan [(7R)-7-hydroxytaxiresinol (3)] were isolated, together with nine known lignans. Among the isolates obtained, α-conidendrin (12) showed strong CYP3A4 inhibition with an IC(50) value of 0.2 μM. Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Colletotrichum; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Screening Assays, Antitumor; Free Radical Scavengers; Furans; Hep G2 Cells; Humans; Isocoumarins; Isoflavones; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Taxus; Tetrahydronaphthalenes; Wood	2011

Article

Year

Cytochrome P450 3A4 inhibitory constituents of the wood of Taxus yunnanensis.

Journal of natural products, 2011, Jan-28, Volume: 74, Issue:1

From the aqueous extract of the wood of Taxus yunnanensis, which showed cytochrome P450 3A4 (CYP3A4) inhibition, a new isoflavan [(3S,4R)-4'-hydroxy-6,3'-dimethoxyisoflavan-4-ol (1)], a new degraded lignan [2,3-bis(hydroxymethyl)-7-hydroxy-6-methoxy-1-tetralone (2)], and a new lignan [(7R)-7-hydroxytaxiresinol (3)] were isolated, together with nine known lignans. Among the isolates obtained, α-conidendrin (12) showed strong CYP3A4 inhibition with an IC(50) value of 0.2 μM.

Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Colletotrichum; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Screening Assays, Antitumor; Free Radical Scavengers; Furans; Hep G2 Cells; Humans; Isocoumarins; Isoflavones; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Taxus; Tetrahydronaphthalenes; Wood

2011