Compounds > lapatinib
Page last updated: 2024-09-05

lapatinib and tyrphostin ag825

lapatinib has been researched along with tyrphostin ag825 in 3 studies

Compound Research Comparison

Studies
(lapatinib)		Trials
(lapatinib)		Recent Studies (post-2010)
(lapatinib)		Studies
(tyrphostin ag825)		Trials
(tyrphostin ag825)		Recent Studies (post-2010) (tyrphostin ag825)
1,9193051,44245016

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)tyrphostin ag825 (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.35
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.3484

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arteaga, CL; Boimel, PJ; Coniglio, SJ; Hynes, NE; Kedrin, D; Segall, JE; Wyckoff, J1
Ahmad, ZK; Brown, CM; Cueva, RA; Doherty, JK; Ryan, AF1
Bodiga, S; Bodiga, VL; Thokala, S; Vemuri, PK1

Other Studies

3 other study(ies) available for lapatinib and tyrphostin ag825

ArticleYear
ERBB1 and ERBB2 have distinct functions in tumor cell invasion and intravasation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11

    Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cell Movement; ErbB Receptors; Female; Gefitinib; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Quinazolines; Receptor, ErbB-2; Tyrphostins; Xenograft Model Antitumor Assays

2009
ErbB expression, activation, and inhibition with lapatinib and tyrphostin (AG825) in human vestibular schwannomas.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2011, Volume: 32, Issue:5

    Topics: Benzothiazoles; Cell Cycle; Cell Proliferation; Epidermal Growth Factor; Humans; Lapatinib; Neuroma, Acoustic; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Signal Transduction; Tumor Cells, Cultured; Tyrphostins

2011
Zinc pyrithione inhibits caspase-3 activity, promotes ErbB1-ErbB2 heterodimerization and suppresses ErbB2 downregulation in cardiomyocytes subjected to ischemia/reperfusion.
    Journal of inorganic biochemistry, 2015, Volume: 153

    Topics: Amino Acid Chloromethyl Ketones; Animals; Benzothiazoles; Cardiotonic Agents; Caspase 3; Caspase Inhibitors; Cell Hypoxia; Chlorides; Down-Regulation; ErbB Receptors; Lapatinib; Leupeptins; Myocytes, Cardiac; Organometallic Compounds; Phosphorylation; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Multimerization; Pyridines; Quinazolines; Rats; Receptor, ErbB-2; RNA, Messenger; Thiones; Tyrphostins; Zinc Compounds

2015